CD8 expression up to the double-positive CD3low/intermediate stage of thymic differentiation is sufficient for development of peripheral functional cytotoxic T lymphocytes

Journal of Experimental Medicine

Volumn 194, Issue 5, 2001, Pages 685-693

  Zhang, X L ^a   Zhao, S ^a   Borenstein, S H ^a   Liu, Y ^a   Jayabalasingham, B ^a   Chamberlain, J W ^a  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

Author keywords

CD8; Gene expression; Stage specific regulation; Sublineage commitment; Thymic selection

Indexed keywords

CD8 ANTIGEN; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ARTICLE; CELL POPULATION; CYTOTOXIC T LYMPHOCYTE; KNOCKOUT MOUSE; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; THYMOCYTE; THYMUS; TISSUE DIFFERENTIATION;

ANIMALS; ANTIGENS, CD8; ANTIGENS, LY; CYTOTOXICITY, IMMUNOLOGIC; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, KNOCKOUT; MICE, TRANSGENIC; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SKIN TRANSPLANTATION; SPLEEN; T-LYMPHOCYTES; T-LYMPHOCYTES, CYTOTOXIC; THYMUS GLAND; TRANSCRIPTION, GENETIC;

EID: 0035801606     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.194.5.685     Document Type: Article

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