Nanoparticle-delivered suicide gene therapy effectively reduces ovarian tumor burden in mice

Cancer Research

Volumn 69, Issue 15, 2009, Pages 6184-6191

  Huang, Yu Hung ^a   Zugates, Gregory T ^b   Peng, Weidan ^a   Holtz, David ^a   Dunton, Charles ^a   Green, Jordan J ^b   Hossain, Naushad ^b   Chernick, Michael R ^a   Padera Jr , Robert F ^d   Langer, Robert ^b,c   Anderson, Daniel G ^b   Sawicki, Janet A ^a,e,f  

^a LANKENAU INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c Massachusetts Institute of Technology Cambridge   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e THOMAS JEFFERSON UNIVERSITY   (United States)

^f THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; DIPHTHERIA TOXIN; DNA; NANOPARTICLE; PACLITAXEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INCIDENCE; CANCER SURVIVAL; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; GENE THERAPY; HUMAN; HUMAN CELL; LIFESPAN; METASTASIS; MOUSE; NONHUMAN; OVARY CANCER; PRIORITY JOURNAL; PROMOTER REGION; SUICIDE GENE; TUMOR XENOGRAFT;

ANIMALS; DNA; EPIDIDYMAL SECRETORY PROTEINS; FEMALE; GENE THERAPY; GENETIC VECTORS; HUMANS; MEMBRANE GLYCOPROTEINS; MICE; NANOPARTICLES; OVARIAN NEOPLASMS; POLYMERS; PROMOTER REGIONS, GENETIC; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 68049117233     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-0061     Document Type: Article

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