Binding mechanism and synergetic effects of xanthone derivatives as noncompetitive α-glucosidase inhibitors: A theoretical and experimental study

Journal of Physical Chemistry B

Volumn 117, Issue 43, 2013, Pages 13464-13471

  Liu, Yan ^a   Ma, Lin ^a   Chen, Wen Hua ^b   Park, Hwangseo ^c   Ke, Zhuofeng ^a   Wang, Bo ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

^c Sejong University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING MECHANISMS; DOCKING SIMULATIONS; GLUCOSIDASE INHIBITORS; INHIBITORY ACTIVITY; SECONDARY STRUCTURES; STACKING INTERACTION; SYNERGETIC EFFECT; THEORETICAL STUDY;

PHYSICAL CHEMISTRY; PHYSICS;

BINDING ENERGY;

ALPHA GLUCOSIDASE; ENZYME INHIBITOR; XANTHONE DERIVATIVE;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; ENZYMOLOGY; KINETICS; METABOLISM; SACCHAROMYCES CEREVISIAE; STRUCTURE ACTIVITY RELATION;

ALPHA-GLUCOSIDASES; BINDING SITES; DRUG SYNERGISM; ENZYME INHIBITORS; KINETICS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; SACCHAROMYCES CEREVISIAE; STRUCTURE-ACTIVITY RELATIONSHIP; XANTHONES;

EID: 84887100322     PISSN: 15206106     EISSN: 15205207     Source Type: Journal    
DOI: 10.1021/jp4067235     Document Type: Article

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