-
1
-
-
0019644298
-
The aging process
-
6947277 10.1073/pnas.78.11.7124 1:CAS:528:DyaL38XktFGk
-
Harman D (1981) The aging process. Proc Natl Acad Sci USA 78:7124-7128
-
(1981)
Proc Natl Acad Sci USA
, vol.78
, pp. 7124-7128
-
-
Harman, D.1
-
2
-
-
0030038103
-
Oxidative stress, caloric restriction, and aging
-
8658196 10.1126/science.273.5271.59 1:STN:280:DyaK283nsFGruw%3D%3D
-
Sohal RS, Weindruch R (1996) Oxidative stress, caloric restriction, and aging. Science 273:59-63
-
(1996)
Science
, vol.273
, pp. 59-63
-
-
Sohal, R.S.1
Weindruch, R.2
-
3
-
-
0021654713
-
Genomic plasticity in aging human cells
-
6443554 1:STN:280:DyaL28%2FltV2lsg%3D%3D
-
Goldstein S, Shmookler RJ (1984) Genomic plasticity in aging human cells. Annu Rev Gerontol Geriatr 4:33-57
-
(1984)
Annu Rev Gerontol Geriatr
, vol.4
, pp. 33-57
-
-
Goldstein, S.1
Shmookler, R.J.2
-
4
-
-
0021675169
-
Urate and ascorbate: Their possible roles as antioxidants in determining longevity of mammalian species
-
10.1016/0167-4943(84)90033-5
-
Culter RG (1984) Urate and ascorbate: their possible roles as antioxidants in determining longevity of mammalian species. Arch Gerontol Geriatr 3:321-348
-
(1984)
Arch Gerontol Geriatr
, vol.3
, pp. 321-348
-
-
Culter, R.G.1
-
5
-
-
0026663037
-
A novel hypothesis of lipofuscinogenesis and cellular aging based on interactions between oxidative stress and autophagocytosis
-
1383780 10.1016/0921-8734(92)90042-N 1:CAS:528:DyaK38XmsV2iurg%3D
-
Brunk UT, Jones CB, Sohal RS (1992) A novel hypothesis of lipofuscinogenesis and cellular aging based on interactions between oxidative stress and autophagocytosis. Mutat Res 275:395-403
-
(1992)
Mutat Res
, vol.275
, pp. 395-403
-
-
Brunk, U.T.1
Jones, C.B.2
Sohal, R.S.3
-
6
-
-
0022414005
-
Fine structural analysis of lipofuscin in various tissues of rats of different ages
-
4079478 10.1016/0047-6374(85)90110-1 1:CAS:528:DyaL28Xms1Gntw%3D%3D
-
Ikeda H, Tauchi H, Sato T (1985) Fine structural analysis of lipofuscin in various tissues of rats of different ages. Mech Ageing Dev 33:77-93
-
(1985)
Mech Ageing Dev
, vol.33
, pp. 77-93
-
-
Ikeda, H.1
Tauchi, H.2
Sato, T.3
-
7
-
-
33745275797
-
Pin1 protein associates with neuronal lipofuscin: Potential consequences in age-related neurodegeneration
-
16480979 10.1016/j.expneurol.2005.12.030 1:CAS:528:DC%2BD28XmtlGmtrw%3D
-
Hashemzadeh-Bonehi L, Phillips RG, Cairns NJ, Mosaheb S, Thorpe JR (2006) Pin1 protein associates with neuronal lipofuscin: potential consequences in age-related neurodegeneration. Exp Neurol 199:328-338
-
(2006)
Exp Neurol
, vol.199
, pp. 328-338
-
-
Hashemzadeh-Bonehi, L.1
Phillips, R.G.2
Cairns, N.J.3
Mosaheb, S.4
Thorpe, J.R.5
-
8
-
-
84861189161
-
Age-related changes in the mesial temporal lobe: The parahippocampal white matter region
-
Stoub T, Barnes CA, Shah RC, Stebbins GT, Ferrari C, Detoledo-Morrell L (2012) Age-related changes in the mesial temporal lobe: the parahippocampal white matter region. Neurobiol Aging 33:1168-1176
-
(2012)
Neurobiol Aging
, vol.33
, pp. 1168-1176
-
-
Stoub, T.1
Barnes, C.A.2
Shah, R.C.3
Stebbins, G.T.4
Ferrari, C.5
Detoledo-Morrell, L.6
-
9
-
-
67650505038
-
Neurobiological changes in the hippocampus during normative aging
-
19597084 10.1001/archneurol.2009.125
-
Lister JP, Barnes CA (2009) Neurobiological changes in the hippocampus during normative aging. Arch Neurol 66:829-833
-
(2009)
Arch Neurol
, vol.66
, pp. 829-833
-
-
Lister, J.P.1
Barnes, C.A.2
-
10
-
-
0021335871
-
Senescent microstructural changes in rat cerebellum
-
6199084 10.1016/0006-8993(84)90886-2 1:STN:280:DyaL2c7ivFCqtw%3D%3D
-
Rogers J, Zornetzer SF, Bloom FE, Mervis RE (1984) Senescent microstructural changes in rat cerebellum. Brain Res 292:23-32
-
(1984)
Brain Res
, vol.292
, pp. 23-32
-
-
Rogers, J.1
Zornetzer, S.F.2
Bloom, F.E.3
Mervis, R.E.4
-
11
-
-
0018638769
-
Loss of synapses in the cerebellar cortex of the senescent rat
-
512301 10.1093/geronj/34.6.818 1:STN:280:DyaL3c%2FntlWhuw%3D%3D
-
Glick R, Bondareff W (1979) Loss of synapses in the cerebellar cortex of the senescent rat. J Gerontol 34:818-822
-
(1979)
J Gerontol
, vol.34
, pp. 818-822
-
-
Glick, R.1
Bondareff, W.2
-
12
-
-
0033523489
-
Age-related changes in the cerebellum: Parallel fibers
-
10517962 10.1016/S0006-8993(99)01707-2 1:CAS:528:DyaK1MXmtlGqtrk%3D
-
Huang CM, Brown N, Huang RH (1999) Age-related changes in the cerebellum: parallel fibers. Brain Res 840:148-152
-
(1999)
Brain Res
, vol.840
, pp. 148-152
-
-
Huang, C.M.1
Brown, N.2
Huang, R.H.3
-
13
-
-
69049091784
-
The electrotonic structure of pyramidal neurons contributing to prefrontal cortical circuits in macaque monkeys is significantly altered in aging
-
19150923 10.1093/cercor/bhn242
-
Kabaso D, Coskren PJ, Henry BI, Hof PR, Wearne SL (2009) The electrotonic structure of pyramidal neurons contributing to prefrontal cortical circuits in macaque monkeys is significantly altered in aging. Cereb Cortex 19:2248-2268
-
(2009)
Cereb Cortex
, vol.19
, pp. 2248-2268
-
-
Kabaso, D.1
Coskren, P.J.2
Henry, B.I.3
Hof, P.R.4
Wearne, S.L.5
-
14
-
-
34249025187
-
Changes in the structural complexity of the aged brain
-
17465981 10.1111/j.1474-9726.2007.00289.x 1:CAS:528:DC%2BD2sXntVKqu7o%3D
-
Dickstein DL, Kabaso D, Rocher AB, Luebke JI, Wearne SL, Hof PR (2007) Changes in the structural complexity of the aged brain. Aging Cell 6:275-284
-
(2007)
Aging Cell
, vol.6
, pp. 275-284
-
-
Dickstein, D.L.1
Kabaso, D.2
Rocher, A.B.3
Luebke, J.I.4
Wearne, S.L.5
Hof, P.R.6
-
15
-
-
77950229880
-
Neural mechanisms of ageing and cognitive decline
-
20336135 10.1038/nature08983 1:CAS:528:DC%2BC3cXjvVGlu7o%3D
-
Bishop NA, Lu T, Yankner BA (2010) Neural mechanisms of ageing and cognitive decline. Nature 464:529-535
-
(2010)
Nature
, vol.464
, pp. 529-535
-
-
Bishop, N.A.1
Lu, T.2
Yankner, B.A.3
-
17
-
-
0030738721
-
Apoptosis in dopaminergic neurons of the human substantia nigra during normal aging
-
9225140 1:CAS:528:DyaK2sXls1WlsLg%3D
-
Anglade P, Vyas S, Hirsch EC, Agid Y (1997) Apoptosis in dopaminergic neurons of the human substantia nigra during normal aging. Histol Histopathol 12:603-610
-
(1997)
Histol Histopathol
, vol.12
, pp. 603-610
-
-
Anglade, P.1
Vyas, S.2
Hirsch, E.C.3
Agid, Y.4
-
18
-
-
0031738297
-
Normal and pathological aging-findings of positron-emission-tomography
-
9869321 10.1007/s007020050097 1:STN:280:DyaK1M%2FosVKltA%3D%3D
-
Mielke R, Kessler J, Szelies B, Herholz K, Wienhard K, Heiss WD (1998) Normal and pathological aging-findings of positron-emission-tomography. J Neural Transm 105:821-837
-
(1998)
J Neural Transm
, vol.105
, pp. 821-837
-
-
Mielke, R.1
Kessler, J.2
Szelies, B.3
Herholz, K.4
Wienhard, K.5
Heiss, W.D.6
-
19
-
-
0030773657
-
Normal human aging: Factors contributing to cerebral atrophy
-
9395125 10.1016/S0022-510X(97)00141-X
-
Akiyama H, Meyer JS, Mortel KF, Terayama Y, Thornby JI, Konno S (1997) Normal human aging: factors contributing to cerebral atrophy. J Neurol Sci 152:39-49
-
(1997)
J Neurol Sci
, vol.152
, pp. 39-49
-
-
Akiyama, H.1
Meyer, J.S.2
Mortel, K.F.3
Terayama, Y.4
Thornby, J.I.5
Konno, S.6
-
20
-
-
36248934296
-
Clinical neurophysiology of aging brain: From normal aging to neurodegeneration
-
17870229 10.1016/j.pneurobio.2007.07.010 1:CAS:528:DC%2BD2sXhtlGjsL3J
-
Rossini PM, Rossi S, Babiloni C, Polich J (2007) Clinical neurophysiology of aging brain: from normal aging to neurodegeneration. Prog Neurobiol 83:375-400
-
(2007)
Prog Neurobiol
, vol.83
, pp. 375-400
-
-
Rossini, P.M.1
Rossi, S.2
Babiloni, C.3
Polich, J.4
-
21
-
-
78149367335
-
Biology of aging brain
-
21045377 10.4103/0377-4929.71995 1:STN:280:DC%2BC3cbktlShsQ%3D%3D
-
Shankar SK (2010) Biology of aging brain. Indian J Pathol Microbiol 53:595-604
-
(2010)
Indian J Pathol Microbiol
, vol.53
, pp. 595-604
-
-
Shankar, S.K.1
-
22
-
-
14944356256
-
2+ and mitochondria as substrates for deficits in synaptic plasticity in normal brain ageing
-
15256066 10.1111/j.1582-4934.2004.tb00273.x 1:CAS:528: DC%2BD2MXlt1Kqt7c%3D
-
2+ and mitochondria as substrates for deficits in synaptic plasticity in normal brain ageing. J Cell Mol Med 8:181-190
-
(2004)
J Cell Mol Med
, vol.8
, pp. 181-190
-
-
Toescu, E.C.1
Verkhratsky, A.2
-
23
-
-
20144371478
-
Age-related calcium changes, oxyradical damage, caspase activation and nuclear condensation in hippocampal neurons in response to glutamate and beta-amyloid
-
15919595 10.1016/j.exger.2005.03.007 1:CAS:528:DC%2BD2MXks1Wgurc%3D
-
Brewer GJ, Lim A, Capps NG, Torricelli JR (2005) Age-related calcium changes, oxyradical damage, caspase activation and nuclear condensation in hippocampal neurons in response to glutamate and beta-amyloid. Exp Gerontol 40:426-437
-
(2005)
Exp Gerontol
, vol.40
, pp. 426-437
-
-
Brewer, G.J.1
Lim, A.2
Capps, N.G.3
Torricelli, J.R.4
-
24
-
-
0029862743
-
Reduction in the number of NADPH-diaphorase-positive cells in the cerebral cortex and striatum in aged rats
-
8861109 10.1016/0168-0102(95)01020-3 1:CAS:528:DyaK28XjtV2nsL4%3D
-
Yamada K, Noda Y, Komori Y, Sugihara H, Hasegawa T, Nabeshima T (1996) Reduction in the number of NADPH-diaphorase-positive cells in the cerebral cortex and striatum in aged rats. Neurosci Res 24:393-402
-
(1996)
Neurosci Res
, vol.24
, pp. 393-402
-
-
Yamada, K.1
Noda, Y.2
Komori, Y.3
Sugihara, H.4
Hasegawa, T.5
Nabeshima, T.6
-
25
-
-
0038198881
-
Neurons, glia, and plasticity in normal brain aging
-
10.1016/S0197-4580(03)00051-4
-
Finch CE (2003) Neurons, glia, and plasticity in normal brain aging. Neurobiol Aging 24:123-127
-
(2003)
Neurobiol Aging
, vol.24
, pp. 123-127
-
-
Finch, C.E.1
-
26
-
-
0035317868
-
Eyeblink classical conditioning differentiates normal aging from Alzheimer's disease
-
11666044 10.1007/BF02734044 1:STN:280:DC%2BD3MrmsVShuw%3D%3D
-
Woodruff-Pak DS (2001) Eyeblink classical conditioning differentiates normal aging from Alzheimer's disease. Integr Physiol Behav Sci 36:87-108
-
(2001)
Integr Physiol Behav Sci
, vol.36
, pp. 87-108
-
-
Woodruff-Pak, D.S.1
-
27
-
-
77049308856
-
Aging: A theory based on free radical and radiation chemistry
-
13332224 10.1093/geronj/11.3.298 1:STN:280:DyaG28%2FosVygsw%3D%3D
-
Harman D (1956) Aging: a theory based on free radical and radiation chemistry. J Gerontol 11:298-300
-
(1956)
J Gerontol
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
28
-
-
0020644952
-
Superoxide radical: An endogenous toxicant
-
6307121 10.1146/annurev.pa.23.040183.001323 1:CAS:528:DyaL3sXktFOmsbw%3D
-
Fridovich I (1983) Superoxide radical: an endogenous toxicant. Annu Rev Pharmacol Toxicol 23:239-257
-
(1983)
Annu Rev Pharmacol Toxicol
, vol.23
, pp. 239-257
-
-
Fridovich, I.1
-
29
-
-
0027502430
-
Sources and role of iron in lipid peroxidation
-
8477003 10.1021/tx00032a001 1:CAS:528:DyaK3sXht1Wru7c%3D
-
Minotti G (1993) Sources and role of iron in lipid peroxidation. Chem Res Toxicol 6:134-146
-
(1993)
Chem Res Toxicol
, vol.6
, pp. 134-146
-
-
Minotti, G.1
-
30
-
-
0026795635
-
Protein oxidation and aging
-
1355616 10.1126/science.1355616 1:CAS:528:DyaK38Xls1yitrk%3D
-
Stadtman ER (1992) Protein oxidation and aging. Science 257:1220-1224
-
(1992)
Science
, vol.257
, pp. 1220-1224
-
-
Stadtman, E.R.1
-
31
-
-
1642410790
-
Activation of apoptosis signal-regulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation
-
14688258 10.1074/jbc.M311129200 1:CAS:528:DC%2BD2cXhvFChs78%3D
-
Goldman EH, Chen L, Fu H (2004) Activation of apoptosis signal-regulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation. J Biol Chem 279:10442-10449
-
(2004)
J Biol Chem
, vol.279
, pp. 10442-10449
-
-
Goldman, E.H.1
Chen, L.2
Fu, H.3
-
32
-
-
0027171266
-
Oxidants, antioxidants, and the degenerative diseases of aging
-
8367443 10.1073/pnas.90.17.7915 1:CAS:528:DyaK3sXmtVSksL4%3D
-
Ames BN, Shigenaga MK, Hagen TM (1993) Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci USA 90:7915-7922
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 7915-7922
-
-
Ames, B.N.1
Shigenaga, M.K.2
Hagen, T.M.3
-
33
-
-
13244292394
-
Time-course of mitochondrial gene expressions in mice brains: Implications for mitochondrial dysfunction, oxidative damage, and cytochrom c in aging
-
15659220 10.1111/j.1471-4159.2004.02884.x 1:CAS:528:DC%2BD2MXht12ms7c%3D
-
Manczak M, Jung Y, Park BS, Partovi D, Reddy PH (2005) Time-course of mitochondrial gene expressions in mice brains: implications for mitochondrial dysfunction, oxidative damage, and cytochrom c in aging. J Neurochem 92:494-504
-
(2005)
J Neurochem
, vol.92
, pp. 494-504
-
-
Manczak, M.1
Jung, Y.2
Park, B.S.3
Partovi, D.4
Reddy, P.H.5
-
34
-
-
33646708957
-
Proteomics analysis provides insight into caloric restriction mediated oxidation and expression of brain proteins associated with age-related impaired cellular processes: Mitochondrial dysfunction, glutamate dysregulation and impaired protein synthesis
-
15996793 10.1016/j.neurobiolaging.2005.05.014 1:CAS:528: DC%2BD28XkvVOnsbw%3D
-
Poon HF, Shepherd HM, Reed TT et al (2006) Proteomics analysis provides insight into caloric restriction mediated oxidation and expression of brain proteins associated with age-related impaired cellular processes: mitochondrial dysfunction, glutamate dysregulation and impaired protein synthesis. Neurobiol Aging 27:1020-1034
-
(2006)
Neurobiol Aging
, vol.27
, pp. 1020-1034
-
-
Poon, H.F.1
Shepherd, H.M.2
Reed, T.T.3
-
35
-
-
0015319592
-
The biologic clock: The mitochondria?
-
5016631 1:STN:280:DyaE387lsVCmug%3D%3D
-
Harman D (1972) The biologic clock: the mitochondria? J Am Geriatr Soc 20:145-147
-
(1972)
J Am Geriatr Soc
, vol.20
, pp. 145-147
-
-
Harman, D.1
-
36
-
-
74449091894
-
Reactive oxygen species (ROS) in the human neocortex: Role of aging and cognition
-
19854245 10.1016/j.brainresbull.2009.10.011 1:CAS:528: DC%2BC3cXhtVGltLs%3D
-
Brawek B, Loffler M, Wagner K et al (2010) Reactive oxygen species (ROS) in the human neocortex: role of aging and cognition. Brain Res Bull 81:484-490
-
(2010)
Brain Res Bull
, vol.81
, pp. 484-490
-
-
Brawek, B.1
Loffler, M.2
Wagner, K.3
-
37
-
-
0037085019
-
Control of oxidative phosphorylation by Complex i in rat liver mitochondria: Implications for aging
-
11997134 10.1016/S0005-2728(01)00246-8 1:CAS:528:DC%2BD38XktVKns78%3D
-
Ventura B, Genova ML, Bovina C, Formiggini G, Lenaz G (2002) Control of oxidative phosphorylation by Complex I in rat liver mitochondria: implications for aging. Biochim Biophys Acta 1553:249-260
-
(2002)
Biochim Biophys Acta
, vol.1553
, pp. 249-260
-
-
Ventura, B.1
Genova, M.L.2
Bovina, C.3
Formiggini, G.4
Lenaz, G.5
-
38
-
-
77249155512
-
Age-related changes in mitochondrial respiration and oxidative damage in the cerebral cortex of the Fischer 344 rat
-
20080122 10.1016/j.mad.2009.12.011 1:CAS:528:DC%2BC3cXitVKjtrY%3D
-
Gilmer LK, Ansari MA, Roberts KN, Scheff SW (2010) Age-related changes in mitochondrial respiration and oxidative damage in the cerebral cortex of the Fischer 344 rat. Mech Ageing Dev 131:133-143
-
(2010)
Mech Ageing Dev
, vol.131
, pp. 133-143
-
-
Gilmer, L.K.1
Ansari, M.A.2
Roberts, K.N.3
Scheff, S.W.4
-
39
-
-
30544442097
-
Acetylcarnitine and cellular stress response: Roles in nutritional redox homeostasis and regulation of longevity genes
-
16413418 10.1016/j.jnutbio.2005.03.027 1:CAS:528:DC%2BD28XksVaksA%3D%3D
-
Calabrese V, Giuffrida Stella AM, Calvani M, Butterfield DA (2006) Acetylcarnitine and cellular stress response: roles in nutritional redox homeostasis and regulation of longevity genes. J Nutr Biochem 17:73-88
-
(2006)
J Nutr Biochem
, vol.17
, pp. 73-88
-
-
Calabrese, V.1
Giuffrida Stella, A.M.2
Calvani, M.3
Butterfield, D.A.4
-
40
-
-
1042302135
-
The cardiolipin-cytochrome c interaction and the mitochondrial regulation of apoptosis
-
14989263 10.1016/j.abb.2003.12.002 1:CAS:528:DC%2BD2cXhtV2hsrk%3D
-
Iverson SL, Orrenius S (2004) The cardiolipin-cytochrome c interaction and the mitochondrial regulation of apoptosis. Arch Biochem Biophys 423:37-46
-
(2004)
Arch Biochem Biophys
, vol.423
, pp. 37-46
-
-
Iverson, S.L.1
Orrenius, S.2
-
41
-
-
77955086827
-
Repeats, longevity and the sources of mtDNA deletions: Evidence from 'deletional spectra'
-
20591530 10.1016/j.tig.2010.05.006
-
Guo X, Popadin KY, Markuzon N et al (2010) Repeats, longevity and the sources of mtDNA deletions: evidence from 'deletional spectra'. Trends Genet 26:340-343
-
(2010)
Trends Genet
, vol.26
, pp. 340-343
-
-
Guo, X.1
Popadin, K.Y.2
Markuzon, N.3
-
42
-
-
78649981260
-
Functional genomics of brain aging and Alzheimer's disease: Focus on selective neuronal vulnerability
-
21629439 10.2174/138920210793360943
-
Wang X, Michaelis ML, Michaelis EK (2010) Functional genomics of brain aging and Alzheimer's disease: focus on selective neuronal vulnerability. Curr Genomics 11:618-633
-
(2010)
Curr Genomics
, vol.11
, pp. 618-633
-
-
Wang, X.1
Michaelis, M.L.2
Michaelis, E.K.3
-
43
-
-
0025149002
-
Quantitative determination of deleted mitochondrial DNA relative to normal DNA in parkinsonian striatum by a kinetic PCR analysis
-
2241948 10.1016/0006-291X(90)90698-M 1:CAS:528:DyaK3MXktlek
-
Ozawa T, Tanaka M, Ikebe S, Ohno K, Kondo T, Mizuno Y (1990) Quantitative determination of deleted mitochondrial DNA relative to normal DNA in parkinsonian striatum by a kinetic PCR analysis. Biochem Biophys Res Commun 172:483-489
-
(1990)
Biochem Biophys Res Commun
, vol.172
, pp. 483-489
-
-
Ozawa, T.1
Tanaka, M.2
Ikebe, S.3
Ohno, K.4
Kondo, T.5
Mizuno, Y.6
-
44
-
-
0027949202
-
Oxidative damage and mitochondrial decay in aging
-
7971961 10.1073/pnas.91.23.10771 1:CAS:528:DyaK2cXmvFyjtL4%3D
-
Shigenaga MK, Hagen MT, Ames BN (1994) Oxidative damage and mitochondrial decay in aging. Proc Natl Acad Sci USA 91:10771-10778
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 10771-10778
-
-
Shigenaga, M.K.1
Hagen, M.T.2
Ames, B.N.3
-
45
-
-
0033945846
-
Mitochondrial oxidative stress plays a key role in aging and apoptosis
-
10902575 10.1080/152165400410281 1:CAS:528:DC%2BD3cXks12htrk%3D
-
Sastre J, Pallardo FV, Vina J (2000) Mitochondrial oxidative stress plays a key role in aging and apoptosis. IUBMB Life 49:427-435
-
(2000)
IUBMB Life
, vol.49
, pp. 427-435
-
-
Sastre, J.1
Pallardo, F.V.2
Vina, J.3
-
46
-
-
0027278557
-
Instability and decay of the primary structure of DNA
-
8469282 10.1038/362709a0 1:CAS:528:DyaK3sXktVeitbo%3D
-
Lindahl T (1993) Instability and decay of the primary structure of DNA. Nature 362:709-715
-
(1993)
Nature
, vol.362
, pp. 709-715
-
-
Lindahl, T.1
-
47
-
-
1642602686
-
Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks
-
14755273 10.1038/ncb1095 1:CAS:528:DC%2BD2cXosFShtA%3D%3D
-
Sedelnikova OA, Horikawa I, Zimonjic DB, Popescu NC, Bonner WM, Barrett JC (2004) Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks. Nat Cell Biol 6:168-170
-
(2004)
Nat Cell Biol
, vol.6
, pp. 168-170
-
-
Sedelnikova, O.A.1
Horikawa, I.2
Zimonjic, D.B.3
Popescu, N.C.4
Bonner, W.M.5
Barrett, J.C.6
-
48
-
-
0028953024
-
Identification of neuronal programmed cell death in situ in the striatum of normal adult rat brain and its relationship to neuronal death during aging
-
7606465 10.1016/0006-8993(95)00197-X 1:CAS:528:DyaK2MXltlyqsr0%3D
-
Zhang L, Kokkonen G, Roth GS (1995) Identification of neuronal programmed cell death in situ in the striatum of normal adult rat brain and its relationship to neuronal death during aging. Brain Res 677:177-179
-
(1995)
Brain Res
, vol.677
, pp. 177-179
-
-
Zhang, L.1
Kokkonen, G.2
Roth, G.S.3
-
49
-
-
1442286547
-
Apoptotic proteins in the course of aging of central nervous system in the rat
-
15122998 10.1016/j.resp.2003.10.009 1:CAS:528:DC%2BD2cXhslequrg%3D
-
Dorszewska J, Adamczewska-Goncerzewicz Z, Szczech J (2004) Apoptotic proteins in the course of aging of central nervous system in the rat. Respir Physiol Neurobiol 139:145-155
-
(2004)
Respir Physiol Neurobiol
, vol.139
, pp. 145-155
-
-
Dorszewska, J.1
Adamczewska-Goncerzewicz, Z.2
Szczech, J.3
-
50
-
-
0036751954
-
Oxidative stress in brain aging. Implications for therapeutics of neurodegenerative diseases
-
12392783 10.1016/S0197-4580(02)00019-2 1:CAS:528:DC%2BD38XotVCiurk%3D
-
Floyd RA, Hensley K (2002) Oxidative stress in brain aging. Implications for therapeutics of neurodegenerative diseases. Neurobiol Aging 23:795-807
-
(2002)
Neurobiol Aging
, vol.23
, pp. 795-807
-
-
Floyd, R.A.1
Hensley, K.2
-
51
-
-
0027527023
-
Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain
-
8215249 10.1002/ana.410340416 1:CAS:528:DyaK2cXitFCgsbk%3D
-
Mecocci P, MacGarvey U, Kaufman AE et al (1993) Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain. Ann Neurol 34:609-616
-
(1993)
Ann Neurol
, vol.34
, pp. 609-616
-
-
Mecocci, P.1
Macgarvey, U.2
Kaufman, A.E.3
-
52
-
-
0026698066
-
An update on the mitochondrial-DNA mutation hypothesis of cell aging
-
1383762 10.1016/0921-8734(92)90024-J 1:CAS:528:DyaK38XmsVyqtr8%3D
-
Miquel J (1992) An update on the mitochondrial-DNA mutation hypothesis of cell aging. Mutat Res 275:209-216
-
(1992)
Mutat Res
, vol.275
, pp. 209-216
-
-
Miquel, J.1
-
53
-
-
0025902273
-
Endogenous mutagens and the causes of aging and cancer
-
1944345 10.1016/0027-5107(91)90157-J 1:CAS:528:DyaK38Xhsl2n
-
Ames BN, Gold LS (1991) Endogenous mutagens and the causes of aging and cancer. Mutat Res 250:3-16
-
(1991)
Mutat Res
, vol.250
, pp. 3-16
-
-
Ames, B.N.1
Gold, L.S.2
-
54
-
-
1642317053
-
Oxidative damage to DNA, p53 gene expression and p53 protein level in the process of aging in rat brain
-
15122989 10.1016/j.resp.2003.10.005 1:CAS:528:DC%2BD2cXisVSkt7w%3D
-
Dorszewska J, Adamczewska-Goncerzewicz Z (2004) Oxidative damage to DNA, p53 gene expression and p53 protein level in the process of aging in rat brain. Respir Physiol Neurobiol 139:227-236
-
(2004)
Respir Physiol Neurobiol
, vol.139
, pp. 227-236
-
-
Dorszewska, J.1
Adamczewska-Goncerzewicz, Z.2
-
55
-
-
0018092182
-
Local cerebral glucose utilization in the normal conscious macaque monkey
-
103488 10.1002/ana.410040402 1:CAS:528:DyaE1MXhvFOqug%3D%3D
-
Kennedy C, Sakurada O, Shinohara M, Jehle J, Sokoloff L (1978) Local cerebral glucose utilization in the normal conscious macaque monkey. Ann Neurol 4:293-301
-
(1978)
Ann Neurol
, vol.4
, pp. 293-301
-
-
Kennedy, C.1
Sakurada, O.2
Shinohara, M.3
Jehle, J.4
Sokoloff, L.5
-
56
-
-
70349084193
-
Age-dependent down-regulation of mitochondrial 8-oxoguanine DNA glycosylase in SAM-P/8 mouse brain and its effect on brain aging
-
19594329 10.1089/rej.2009.0849 1:CAS:528:DC%2BD1MXos1Sktbo%3D
-
Tian F, Tong TJ, Zhang ZY, McNutt MA, Liu XW (2009) Age-dependent down-regulation of mitochondrial 8-oxoguanine DNA glycosylase in SAM-P/8 mouse brain and its effect on brain aging. Rejuvenation Res 12:209-215
-
(2009)
Rejuvenation Res
, vol.12
, pp. 209-215
-
-
Tian, F.1
Tong, T.J.2
Zhang, Z.Y.3
McNutt, M.A.4
Liu, X.W.5
-
57
-
-
0034708226
-
Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA
-
10706276 10.1038/35002510 1:CAS:528:DC%2BD3cXhs1Olsr8%3D
-
Bruner SD, Norman DP, Verdine GL (2000) Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA. Nature 403:859-866
-
(2000)
Nature
, vol.403
, pp. 859-866
-
-
Bruner, S.D.1
Norman, D.P.2
Verdine, G.L.3
-
58
-
-
0026772501
-
Redox ribonucleosides. Isolation and characterization of 5-hydroxyuridine, 8-hydroxyguanosine and 8-hydroxyadenosine from Torula yeast RNA
-
Yanagawa H, Ogawa Y, Ueno N (1992) Redox ribonucleosides. Isolation and characterization of 5-hydroxyuridine, 8-hydroxyguanosine and 8-hydroxyadenosine from Torula yeast RNA. J Biol Chem 19:13320-13326
-
(1992)
J Biol Chem
, vol.19
, pp. 13320-13326
-
-
Yanagawa, H.1
Ogawa, Y.2
Ueno, N.3
-
59
-
-
0029919634
-
Somatic point mutations in the p53 gene of human tumors and cell lines: Updated compilation
-
8594564 10.1093/nar/24.1.141 1:CAS:528:DyaK28XnsV2qtw%3D%3D
-
Hollstein M, Shomer B, Greenblatt M et al (1996) Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation. Nucleic Acids Res 24:141-146
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 141-146
-
-
Hollstein, M.1
Shomer, B.2
Greenblatt, M.3
-
60
-
-
0026592966
-
8-Hydroxyguanine, an abundant from of oxidative DNA damage, causes G-T and A-C substitutions
-
1730583 1:CAS:528:DyaK38XjvFWlug%3D%3D
-
Cheng KC, Cahill DS, Kasai H, Nishimura S, Loeb LA (1992) 8-Hydroxyguanine, an abundant from of oxidative DNA damage, causes G-T and A-C substitutions. J Biol Chem 267:166-172
-
(1992)
J Biol Chem
, vol.267
, pp. 166-172
-
-
Cheng, K.C.1
Cahill, D.S.2
Kasai, H.3
Nishimura, S.4
Loeb, L.A.5
-
61
-
-
0025777672
-
Reduced synthesis of mtRNA in isolated mitochondria of senescent rat brain
-
1709016 10.1016/S0006-291X(05)80233-5 1:CAS:528:DyaK3MXisVCqt7s%3D
-
Fernandez-Silva P, Petruzzella V, Fracasso F, Gadaleta MN, Cantatore P (1991) Reduced synthesis of mtRNA in isolated mitochondria of senescent rat brain. Biochem Biophys Res Commun 176:645-653
-
(1991)
Biochem Biophys Res Commun
, vol.176
, pp. 645-653
-
-
Fernandez-Silva, P.1
Petruzzella, V.2
Fracasso, F.3
Gadaleta, M.N.4
Cantatore, P.5
-
62
-
-
0026071518
-
Cellular senescence: A reflection of normal growth control, differentiation, or aging?
-
2055943 10.1002/jcb.240450205 1:CAS:528:DyaK3MXhtFyqtLc%3D
-
Peacocke M, Campisi J (1991) Cellular senescence: a reflection of normal growth control, differentiation, or aging? J Cell Biochem 45:147-155
-
(1991)
J Cell Biochem
, vol.45
, pp. 147-155
-
-
Peacocke, M.1
Campisi, J.2
-
63
-
-
0034564124
-
Immunocytochemical study on the distribution of p53 in the hippocampus and cerebellum of the aged rat
-
11121541 10.1016/S0006-8993(00)02979-6 1:CAS:528:DC%2BD3cXot1yis7Y%3D
-
Chung YH, Shin C, Kim JM, Lee B, Park KH, Cha CI (2000) Immunocytochemical study on the distribution of p53 in the hippocampus and cerebellum of the aged rat. Brain Res 885:137-141
-
(2000)
Brain Res
, vol.885
, pp. 137-141
-
-
Chung, Y.H.1
Shin, C.2
Kim, J.M.3
Lee, B.4
Park, K.H.5
Cha, C.I.6
-
64
-
-
0026656848
-
Regional cerebral oxygen consumption, blood flow and blood volume in healthy human aging
-
10.1001/archneur.1992.00530340029014
-
Marchal G, Rioux P, Petit-Taboue MC et al (1992) Regional cerebral oxygen consumption, blood flow and blood volume in healthy human aging. Arch Neurol 42:1013-1020
-
(1992)
Arch Neurol
, vol.42
, pp. 1013-1020
-
-
Marchal, G.1
Rioux, P.2
Petit-Taboue, M.C.3
-
66
-
-
0035930899
-
Differential expression of rat brain caspase family proteins during development and aging
-
11741299 10.1006/bbrc.2001.6108 1:CAS:528:DC%2BD3MXptVWju7s%3D
-
Shimohama S, Tanino H, Fujimoto S (2001) Differential expression of rat brain caspase family proteins during development and aging. Biochem Biophys Res Commun 289:1063-1066
-
(2001)
Biochem Biophys Res Commun
, vol.289
, pp. 1063-1066
-
-
Shimohama, S.1
Tanino, H.2
Fujimoto, S.3
-
67
-
-
0033107840
-
Aging splenocyte and thymocyte apoptosis is associated with enhanced expression of p53, bax and caspase-3
-
10329482 10.1006/mcbr.1999.0106 1:CAS:528:DyaK1MXksFelu7k%3D
-
Kapasi AA, Singhal PC (1999) Aging splenocyte and thymocyte apoptosis is associated with enhanced expression of p53, bax and caspase-3. Mol Cell Biol Res Commun 1:78-81
-
(1999)
Mol Cell Biol Res Commun
, vol.1
, pp. 78-81
-
-
Kapasi, A.A.1
Singhal, P.C.2
-
68
-
-
1042288472
-
The many roles of apoptosis in immunity as modified by aging and nutritional status
-
14730368 1:CAS:528:DC%2BD2cXlvVelsb4%3D
-
Fraker PJ, Lill-Elghanian DA (2004) The many roles of apoptosis in immunity as modified by aging and nutritional status. J Nutr Health Aging 8:56-63
-
(2004)
J Nutr Health Aging
, vol.8
, pp. 56-63
-
-
Fraker, P.J.1
Lill-Elghanian, D.A.2
-
69
-
-
78751704301
-
Cytokines and neuronal channels: A molecular basis for age-related decline of neuronal function?
-
20869430 10.1016/j.exger.2010.09.008 1:CAS:528:DC%2BC3MXpvV2nsg%3D%3D
-
Viviani B, Boraso M (2011) Cytokines and neuronal channels: a molecular basis for age-related decline of neuronal function? Exp Gerontol 46:199-206
-
(2011)
Exp Gerontol
, vol.46
, pp. 199-206
-
-
Viviani, B.1
Boraso, M.2
-
70
-
-
0029023626
-
Senescent human fibroblasts resist programmed cell death, and failure to suppress bcl-2 is involved
-
7757977 1:CAS:528:DyaK2MXlvFeru7k%3D
-
Wang E (1995) Senescent human fibroblasts resist programmed cell death, and failure to suppress bcl-2 is involved. Cancer Res 55:2284-2292
-
(1995)
Cancer Res
, vol.55
, pp. 2284-2292
-
-
Wang, E.1
-
71
-
-
0032519426
-
Increased apoptosis of T cell subsets in aging humans: Altered expression of Fas (CD95), Fas ligand, Bcl-2 and Bax
-
9469419 1:CAS:528:DyaK1cXhtVymtL8%3D
-
Aggarwal S, Gupta S (1998) Increased apoptosis of T cell subsets in aging humans: altered expression of Fas (CD95), Fas ligand, Bcl-2 and Bax. J Immunol 160:1627-1637
-
(1998)
J Immunol
, vol.160
, pp. 1627-1637
-
-
Aggarwal, S.1
Gupta, S.2
-
72
-
-
0028169004
-
Bcl-2 protein expression in aged brain and neurodegenerative diseases
-
7841373 10.1097/00001756-199410000-00016 1:STN:280:DyaK2M7ktlClsg%3D%3D
-
Migheli A, Cavalla P, Piva R, Giordana MT, Schiffer D (1994) bcl-2 protein expression in aged brain and neurodegenerative diseases. NeuroReport 5:1906-1908
-
(1994)
NeuroReport
, vol.5
, pp. 1906-1908
-
-
Migheli, A.1
Cavalla, P.2
Piva, R.3
Giordana, M.T.4
Schiffer, D.5
-
73
-
-
0035113356
-
Oxidative-stress-dependent up-regulation of Bcl-2 expression in the central nervous system of aged Fisher-344 rats
-
11181830 10.1046/j.1471-4159.2001.00118.x 1:CAS:528:DC%2BD3MXhs12gu70%3D
-
Kaufmann JA, Bickford PC, Taglialatela G (2001) Oxidative-stress- dependent up-regulation of Bcl-2 expression in the central nervous system of aged Fisher-344 rats. J Neurochem 76:1099-1108
-
(2001)
J Neurochem
, vol.76
, pp. 1099-1108
-
-
Kaufmann, J.A.1
Bickford, P.C.2
Taglialatela, G.3
-
74
-
-
0033985183
-
Apoptosis and the nervous system
-
10617101 10.1046/j.1471-4159.2000.0740001.x 1:CAS:528:DC%2BD3cXlt1Kq
-
Sastry PS, Rao KS (2000) Apoptosis and the nervous system. J Neurochem 74:1-20
-
(2000)
J Neurochem
, vol.74
, pp. 1-20
-
-
Sastry, P.S.1
Rao, K.S.2
-
75
-
-
0013784893
-
Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats
-
5861717 10.1002/cne.901240303 1:STN:280:DyaF28%2Fpt1Cmuw%3D%3D
-
Altman J, Das GD (1965) Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats. J Comp Neurol 124:319-335
-
(1965)
J Comp Neurol
, vol.124
, pp. 319-335
-
-
Altman, J.1
Das, G.D.2
-
76
-
-
0034712047
-
Mammalian neural stem cells
-
10688783 10.1126/science.287.5457.1433 1:CAS:528:DC%2BD3cXhsV2qtrg%3D
-
Gage FH (2000) Mammalian neural stem cells. Science 287:1433-1438
-
(2000)
Science
, vol.287
, pp. 1433-1438
-
-
Gage, F.H.1
-
77
-
-
0036469897
-
Neurogenesis in embryos and adult neural stem cells
-
11826093 1:CAS:528:DC%2BD38XhtFygtb4%3D
-
Kintner C (2002) Neurogenesis in embryos and adult neural stem cells. J Neurosci 22:639-643
-
(2002)
J Neurosci
, vol.22
, pp. 639-643
-
-
Kintner, C.1
-
78
-
-
38149116895
-
Adult neurogenesis is functionally associated with AD-like neurodegeneration
-
17980611 10.1016/j.nbd.2007.09.005 1:CAS:528:DC%2BD1cXptlSntQ%3D%3D
-
Chen Q, Nakajima A, Choi SH, Xiong X, Sisodia SS, Tang YP (2008) Adult neurogenesis is functionally associated with AD-like neurodegeneration. Neurobiol Dis 29:316-326
-
(2008)
Neurobiol Dis
, vol.29
, pp. 316-326
-
-
Chen, Q.1
Nakajima, A.2
Choi, S.H.3
Xiong, X.4
Sisodia, S.S.5
Tang, Y.P.6
-
79
-
-
8444227821
-
Reactive oxygen species and synaptic plasticity in the aging hippocampus
-
15541710 10.1016/j.arr.2004.05.002 1:CAS:528:DC%2BD2MXktlWhuw%3D%3D
-
Serrano F, Klann E (2004) Reactive oxygen species and synaptic plasticity in the aging hippocampus. Ageing Res Rev 3:431-443
-
(2004)
Ageing Res Rev
, vol.3
, pp. 431-443
-
-
Serrano, F.1
Klann, E.2
-
80
-
-
13844271818
-
Neural stem cells as therapeutic agents for age-related brain repair
-
15569351 10.1111/j.1474-9728.2004.00132.x 1:CAS:528:DC%2BD2cXhtFSgsrnO
-
Bernal GM, Peterson DA (2004) Neural stem cells as therapeutic agents for age-related brain repair. Aging Cell 3:345-351
-
(2004)
Aging Cell
, vol.3
, pp. 345-351
-
-
Bernal, G.M.1
Peterson, D.A.2
-
81
-
-
78149470437
-
When neurogenesis encounters aging and disease
-
20961627 10.1016/j.tins.2010.09.003 1:CAS:528:DC%2BC3cXhsVagurnO
-
Lazarov O, Mattson MP, Peterson DA, Pimplikar SW, van Praag H (2010) When neurogenesis encounters aging and disease. Trends Neurosci 33:569-579
-
(2010)
Trends Neurosci
, vol.33
, pp. 569-579
-
-
Lazarov, O.1
Mattson, M.P.2
Peterson, D.A.3
Pimplikar, S.W.4
Van Praag, H.5
-
82
-
-
69349090064
-
Age effects on the regulation of adult hippocampal neurogenesis by physical activity and environmental enrichment in the APP23 mouse model of Alzheimer disease
-
19219917 10.1002/hipo.20560 1:CAS:528:DC%2BD1MXhtlyqtr7I
-
Mirochnic S, Wolf S, Staufenbiel M, Kempermann G (2009) Age effects on the regulation of adult hippocampal neurogenesis by physical activity and environmental enrichment in the APP23 mouse model of Alzheimer disease. Hippocampus 19:1008-1018
-
(2009)
Hippocampus
, vol.19
, pp. 1008-1018
-
-
Mirochnic, S.1
Wolf, S.2
Staufenbiel, M.3
Kempermann, G.4
-
83
-
-
0036488190
-
Dietary restriction enhance neurotrophin expression and neurogenesis in the hippocampus of adult mice
-
11905999 10.1046/j.0022-3042.2001.00747.x 1:CAS:528:DC%2BD38Xht1Ohurs%3D
-
Lee J, Seroogy KB, Mattson MP (2002) Dietary restriction enhance neurotrophin expression and neurogenesis in the hippocampus of adult mice. J Neurochem 80:539-547
-
(2002)
J Neurochem
, vol.80
, pp. 539-547
-
-
Lee, J.1
Seroogy, K.B.2
Mattson, M.P.3
-
84
-
-
0038301570
-
Short-term and long-term survival of new neurons in the rat dentate gyrus
-
12717714 10.1002/cne.10675
-
Dayer AG, Ford AA, Cleaver KM, Yassaee M, Cameron HA (2003) Short-term and long-term survival of new neurons in the rat dentate gyrus. J Comp Neurol 460:563-572
-
(2003)
J Comp Neurol
, vol.460
, pp. 563-572
-
-
Dayer, A.G.1
Ford, A.A.2
Cleaver, K.M.3
Yassaee, M.4
Cameron, H.A.5
-
85
-
-
33947544224
-
Less neurogenesis and inflammation in the immature than in the juvenile brain after cerebral hypoxia-ischemia
-
16926844 1:CAS:528:DC%2BD2sXkvFyntb4%3D
-
Qiu L, Zhu C, Wang X et al (2007) Less neurogenesis and inflammation in the immature than in the juvenile brain after cerebral hypoxia-ischemia. J Cereb Blood Flow Metab 27:785-794
-
(2007)
J Cereb Blood Flow Metab
, vol.27
, pp. 785-794
-
-
Qiu, L.1
Zhu, C.2
Wang, X.3
-
86
-
-
34548142245
-
Adult hippocampal neurogenesis and aging
-
17401726 10.1007/s00406-007-0731-5
-
Klempin F, Kempermann G (2007) Adult hippocampal neurogenesis and aging. Eur Arch Psychiatry Clin Neurosci 257:271-280
-
(2007)
Eur Arch Psychiatry Clin Neurosci
, vol.257
, pp. 271-280
-
-
Klempin, F.1
Kempermann, G.2
-
87
-
-
78651412528
-
Immune modulation of learning, memory, neural plasticity and neurogenesis
-
20970492 10.1016/j.bbi.2010.10.015 1:CAS:528:DC%2BC3MXhtVSru7w%3D
-
Yirmiya R, Goshen I (2011) Immune modulation of learning, memory, neural plasticity and neurogenesis. Brain Behav Immun 25:181-213
-
(2011)
Brain Behav Immun
, vol.25
, pp. 181-213
-
-
Yirmiya, R.1
Goshen, I.2
-
88
-
-
79960555700
-
Possible implications in insulin resistance and glucose metabolism in Alzheimer's disease pathogenesis
-
21435176 10.1111/j.1582-4934.2011.01318.x 1:CAS:528:DC%2BC3MXht1ejt7jF
-
Bosco D, Fava A, Plastino M, Montalcini T, Pujia A (2011) Possible implications in insulin resistance and glucose metabolism in Alzheimer's disease pathogenesis. J Cell Mol Med 15:1807-1821
-
(2011)
J Cell Mol Med
, vol.15
, pp. 1807-1821
-
-
Bosco, D.1
Fava, A.2
Plastino, M.3
Montalcini, T.4
Pujia, A.5
-
89
-
-
78751702337
-
IGF-I and the aging mammalian brain
-
20863877 10.1016/j.exger.2010.08.022 1:CAS:528:DC%2BC3MXpvV2nsA%3D%3D
-
Piriz J, Muller A, Trejo JL, Torres-Aleman I (2011) IGF-I and the aging mammalian brain. Exp Gerontol 46:96-99
-
(2011)
Exp Gerontol
, vol.46
, pp. 96-99
-
-
Piriz, J.1
Muller, A.2
Trejo, J.L.3
Torres-Aleman, I.4
-
90
-
-
36549062949
-
Central actions of liver-derived insulin-like growth factor i underlying its pro-cognitive effects
-
17848918 10.1038/sj.mp.4002076 1:CAS:528:DC%2BD2sXhtlKmtLjJ
-
Trejo JL, Piriz J, Llorens-Martin MV et al (2007) Central actions of liver-derived insulin-like growth factor I underlying its pro-cognitive effects. Mol Psychiatry 12:1118-1128
-
(2007)
Mol Psychiatry
, vol.12
, pp. 1118-1128
-
-
Trejo, J.L.1
Piriz, J.2
Llorens-Martin, M.V.3
-
91
-
-
84155163218
-
Reduced brain insulin-like growth factor i function during aging
-
Muller AP, Fernandez AM, Haas C, Zimmer E, Portela LV, Torres-Aleman I (2012) Reduced brain insulin-like growth factor I function during aging. Mol Cell Neurosci 49:9-12
-
(2012)
Mol Cell Neurosci
, vol.49
, pp. 9-12
-
-
Muller, A.P.1
Fernandez, A.M.2
Haas, C.3
Zimmer, E.4
Portela, L.V.5
Torres-Aleman, I.6
-
92
-
-
24144460032
-
Stem/progenitor cell proliferation factors FGF-2, IGF-1, and VEGF exhibit early decline during the course of aging in the hippocampus: Role of astrocytes
-
15800930 10.1002/glia.20187
-
Shetty AK, Hattiangady B, Shetty GA (2005) Stem/progenitor cell proliferation factors FGF-2, IGF-1, and VEGF exhibit early decline during the course of aging in the hippocampus: role of astrocytes. Glia 51:173-186
-
(2005)
Glia
, vol.51
, pp. 173-186
-
-
Shetty, A.K.1
Hattiangady, B.2
Shetty, G.A.3
-
93
-
-
79952611543
-
Exercise training increases size of hippocampus and improves memory
-
21282661 10.1073/pnas.1015950108 1:CAS:528:DC%2BC3MXisVSjsbk%3D
-
Erickson KI, Voss MW, Prakash RS et al (2011) Exercise training increases size of hippocampus and improves memory. Proc Natl Acad Sci USA 108:3017-3022
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 3017-3022
-
-
Erickson, K.I.1
Voss, M.W.2
Prakash, R.S.3
-
94
-
-
84865755929
-
Exercise-induced cognitive plasticity, implications for mild cognitive impairment and Alzheimer's disease
-
21602910 10.3389/fneur.2011.00028 1:CAS:528:DC%2BC3MXos12gtrg%3D
-
Foster PP, Rosenblatt KP, Kuljis RO (2011) Exercise-induced cognitive plasticity, implications for mild cognitive impairment and Alzheimer's disease. Front Neurol 2:28
-
(2011)
Front Neurol
, vol.2
, pp. 28
-
-
Foster, P.P.1
Rosenblatt, K.P.2
Kuljis, R.O.3
-
95
-
-
0027476024
-
A synaptic model of memory: Long-term potentiation in the hippocampus
-
8421494 10.1038/361031a0 1:CAS:528:DyaK3sXntlOntw%3D%3D
-
Bliss TV, Collingridge GL (1993) A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361:31-39
-
(1993)
Nature
, vol.361
, pp. 31-39
-
-
Bliss, T.V.1
Collingridge, G.L.2
-
96
-
-
0015799240
-
Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path
-
4727084 1:STN:280:DyaE3s3ktlersw%3D%3D
-
Bliss TV, Lomo T (1973) Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. J Physiol 232:331-356
-
(1973)
J Physiol
, vol.232
, pp. 331-356
-
-
Bliss, T.V.1
Lomo, T.2
-
97
-
-
0018170559
-
Synaptic enhancement in fascia dentata: Cooperativity among coactive afferents
-
719524 10.1016/0006-8993(78)90030-6 1:STN:280:DyaE1M%2Fmtlemuw%3D%3D
-
McNaughton BL, Douglas RM, Goddard GV (1978) Synaptic enhancement in fascia dentata: cooperativity among coactive afferents. Brain Res 157:277-293
-
(1978)
Brain Res
, vol.157
, pp. 277-293
-
-
McNaughton, B.L.1
Douglas, R.M.2
Goddard, G.V.3
-
98
-
-
0033033642
-
Loss of proteins regulating synaptic plasticity in normal aging of the human brain and in Alzheimer disease
-
10374754 10.1097/00005072-199906000-00008 1:CAS:528:DyaK1MXktVaqt7c%3D
-
Hatanpaa K, Isaacs KR, Shirao T, Brady DR, Rapoport SI (1999) Loss of proteins regulating synaptic plasticity in normal aging of the human brain and in Alzheimer disease. J Neuropathol Exp Neurol 58:637-643
-
(1999)
J Neuropathol Exp Neurol
, vol.58
, pp. 637-643
-
-
Hatanpaa, K.1
Isaacs, K.R.2
Shirao, T.3
Brady, D.R.4
Rapoport, S.I.5
-
99
-
-
0031009292
-
Modulation of actin filament behavior by GAP-43 (neuromodulin) is dependent on the phosphorylation status of serine 41, the protein kinase C site
-
9133376 1:CAS:528:DyaK2sXjt1Wlu7o%3D
-
He Q, Dent EW, Meiri KF (1997) Modulation of actin filament behavior by GAP-43 (neuromodulin) is dependent on the phosphorylation status of serine 41, the protein kinase C site. J Neurosci 17:3515-3524
-
(1997)
J Neurosci
, vol.17
, pp. 3515-3524
-
-
He, Q.1
Dent, E.W.2
Meiri, K.F.3
-
100
-
-
0034279244
-
Circuit-specific alterations in hippocampal synaptophysin immunoreactivity predict spatial learning impairment in aged rats
-
10964964 1:CAS:528:DC%2BD3cXmsVygsrk%3D
-
Smith TD, Adams MM, Gallagher M, Morrison JH, Rapp PR (2000) Circuit-specific alterations in hippocampal synaptophysin immunoreactivity predict spatial learning impairment in aged rats. J Neurosci 20:6587-6593
-
(2000)
J Neurosci
, vol.20
, pp. 6587-6593
-
-
Smith, T.D.1
Adams, M.M.2
Gallagher, M.3
Morrison, J.H.4
Rapp, P.R.5
-
101
-
-
0029808685
-
Phosphorylation of type III beta-tubulin PC12 cell neurites during NGF-induced process outgrowth
-
8951104 10.1002/(SICI)1097-4695(199612)31:4<461: AID-NEU6>3.0.CO;2- 7 1:CAS:528:DyaK2sXisVSrsQ%3D%3D
-
Aletta JM (1996) Phosphorylation of type III beta-tubulin PC12 cell neurites during NGF-induced process outgrowth. J Neurobiol 31:461-475
-
(1996)
J Neurobiol
, vol.31
, pp. 461-475
-
-
Aletta, J.M.1
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