-
2
-
-
0032571148
-
Cyclin-dependent kinase-5 is associated with lipofuscin in motor neurons in amyotrophic lateral sclerosis
-
Bajaj N.P.S., Al-Sarraj S.T., Anderson V., Kibble M., Leigh N., and Miller C.C.J. Cyclin-dependent kinase-5 is associated with lipofuscin in motor neurons in amyotrophic lateral sclerosis. Neurosci. Lett. 245 (1998) 45-48
-
(1998)
Neurosci. Lett.
, vol.245
, pp. 45-48
-
-
Bajaj, N.P.S.1
Al-Sarraj, S.T.2
Anderson, V.3
Kibble, M.4
Leigh, N.5
Miller, C.C.J.6
-
3
-
-
0031916984
-
The free radical theory of aging matures
-
Beckman K.B., and Ames B.N. The free radical theory of aging matures. Physiol. Rev. 78 (1998) 547-581
-
(1998)
Physiol. Rev.
, vol.78
, pp. 547-581
-
-
Beckman, K.B.1
Ames, B.N.2
-
4
-
-
0029845397
-
Cytosolic proteolysis of t by cathepsin D in hippocampus following suppression of cathepsin B and L
-
Bendarski E., and Lynch G. Cytosolic proteolysis of t by cathepsin D in hippocampus following suppression of cathepsin B and L. J. Neurochem. 67 (1996) 1846-1855
-
(1996)
J. Neurochem.
, vol.67
, pp. 1846-1855
-
-
Bendarski, E.1
Lynch, G.2
-
5
-
-
0036710928
-
Lipofuscin: mechanisms of age-related accumulation and influence on cell function
-
Brunk U.T., and Terman A. Lipofuscin: mechanisms of age-related accumulation and influence on cell function. Free Radical Biol. Med. 33 (2002) 611-619
-
(2002)
Free Radical Biol. Med.
, vol.33
, pp. 611-619
-
-
Brunk, U.T.1
Terman, A.2
-
6
-
-
7044262166
-
Clinical and neuropathologic variation in neuronal intermediate filament inclusion disease (NIFID)
-
Cairns N.J., Grossman M., Arnold S.E., Burn D.J., Jaros E., Perry R.H., Duyckaerts C., Stankoff B., Pillon B., Skullerud K., Cruz-Sanchez F.F., Bigio E.H., Mackenzie I.R., Gearing M., Juncos J.L., Glass J.D., Yokoo H., Nakazato Y., Mosaheb S., Thorpe J.R., Uryu K., Lee V.M., and Trojanowski J.Q. Clinical and neuropathologic variation in neuronal intermediate filament inclusion disease (NIFID). Neurology 63 (2004) 1376-1384
-
(2004)
Neurology
, vol.63
, pp. 1376-1384
-
-
Cairns, N.J.1
Grossman, M.2
Arnold, S.E.3
Burn, D.J.4
Jaros, E.5
Perry, R.H.6
Duyckaerts, C.7
Stankoff, B.8
Pillon, B.9
Skullerud, K.10
Cruz-Sanchez, F.F.11
Bigio, E.H.12
Mackenzie, I.R.13
Gearing, M.14
Juncos, J.L.15
Glass, J.D.16
Yokoo, H.17
Nakazato, Y.18
Mosaheb, S.19
Thorpe, J.R.20
Uryu, K.21
Lee, V.M.22
Trojanowski, J.Q.23
more..
-
7
-
-
0037441739
-
Neuronal endosomal/lysosomal membrane destabilization activates caspases and induces abnormal accumulation of the lipid secondary messenger ceramide
-
Ditaranto-Desimone K., Saito M., Tekirian T.L., Saito M., Berg M., Dubowchik G., Soreghan B., Thomas S., Marks N., and Yang A.J. Neuronal endosomal/lysosomal membrane destabilization activates caspases and induces abnormal accumulation of the lipid secondary messenger ceramide. Brain Res. Bull. 59 (2003) 523-531
-
(2003)
Brain Res. Bull.
, vol.59
, pp. 523-531
-
-
Ditaranto-Desimone, K.1
Saito, M.2
Tekirian, T.L.3
Saito, M.4
Berg, M.5
Dubowchik, G.6
Soreghan, B.7
Thomas, S.8
Marks, N.9
Yang, A.J.10
-
8
-
-
0020082425
-
Neuronal liposuscin accumulation in aging and Alzheimer's dementia: a pathogenetic mechanism?
-
Dowson J.H. Neuronal liposuscin accumulation in aging and Alzheimer's dementia: a pathogenetic mechanism?. Br. J. Psychiatry 140 (1982) 142-148
-
(1982)
Br. J. Psychiatry
, vol.140
, pp. 142-148
-
-
Dowson, J.H.1
-
9
-
-
0028022588
-
The lipofuscin content of nerve cells of the inferior olivary nucleus in Alzheimer's disease
-
Drach L.M., Bohl J., and Geobel H.-H. The lipofuscin content of nerve cells of the inferior olivary nucleus in Alzheimer's disease. Dementia 5 (1994) 234-239
-
(1994)
Dementia
, vol.5
, pp. 234-239
-
-
Drach, L.M.1
Bohl, J.2
Geobel, H.-H.3
-
10
-
-
0034843039
-
Sequence of neurofibrillary changes in aging and Alzheimer's disease: a confocal study with phospho-tau antibody, AD2
-
Galvan M., David J.P., Delacourte A., Luna J., and Mena R. Sequence of neurofibrillary changes in aging and Alzheimer's disease: a confocal study with phospho-tau antibody, AD2. J. Alzheimer's Dis. 3 (2001) 417-425
-
(2001)
J. Alzheimer's Dis.
, vol.3
, pp. 417-425
-
-
Galvan, M.1
David, J.P.2
Delacourte, A.3
Luna, J.4
Mena, R.5
-
11
-
-
23944467652
-
Lipofuscin and aging: a matter of toxic waste
-
10.1126/sageke.2005.5.re1
-
Gray D.A., and Woulfe J. Lipofuscin and aging: a matter of toxic waste. Sci. Aging Knowledge Environ. 5 (2005) re1 10.1126/sageke.2005.5.re1
-
(2005)
Sci. Aging Knowledge Environ.
, vol.5
-
-
Gray, D.A.1
Woulfe, J.2
-
12
-
-
0036926421
-
Pin1-A therapeutic target in Alzheimer neurodegeneration
-
Hamdane M., Smet C., Sambo A.V., Leroy A., Wieruszeski J.M., Delobel P., Maurage C.A., Ghestem A., Wintjens R., Begard S., Sergeant N., Delacourte A., Horvath D., Landrieu I., Lippens G., and Buee L. Pin1-A therapeutic target in Alzheimer neurodegeneration. J. Mol. Neurosci. 19 (2002) 275-287
-
(2002)
J. Mol. Neurosci.
, vol.19
, pp. 275-287
-
-
Hamdane, M.1
Smet, C.2
Sambo, A.V.3
Leroy, A.4
Wieruszeski, J.M.5
Delobel, P.6
Maurage, C.A.7
Ghestem, A.8
Wintjens, R.9
Begard, S.10
Sergeant, N.11
Delacourte, A.12
Horvath, D.13
Landrieu, I.14
Lippens, G.15
Buee, L.16
-
13
-
-
0025074187
-
Lipofuscin and ceroid formation: the cellular recycling system
-
Harman D. Lipofuscin and ceroid formation: the cellular recycling system. Adv. Exp. Med. Biol. 266 (1989) 3-15
-
(1989)
Adv. Exp. Med. Biol.
, vol.266
, pp. 3-15
-
-
Harman, D.1
-
14
-
-
0036938198
-
Inverse association of Pin1 and tau accumulation in Alzheimer's disease hippocampus
-
Holzer M., Gartner U., Stobe A., Hartig W., Gruschka H., Bruckner M.K., and Arendt T. Inverse association of Pin1 and tau accumulation in Alzheimer's disease hippocampus. Acta Neuropathol. 104 (2002) 471-481
-
(2002)
Acta Neuropathol.
, vol.104
, pp. 471-481
-
-
Holzer, M.1
Gartner, U.2
Stobe, A.3
Hartig, W.4
Gruschka, H.5
Bruckner, M.K.6
Arendt, T.7
-
15
-
-
0032545149
-
Alz-50/Gallyas-positive lysosome-like intraneuronal granules in Alzheimer's disease and control brains
-
Ikeda K., Akiyama H., Araj T., Kondo H., Haga C., Iritani S., and Kuniaki T. Alz-50/Gallyas-positive lysosome-like intraneuronal granules in Alzheimer's disease and control brains. Neurosci. Lett. 258 (1998) 113-116
-
(1998)
Neurosci. Lett.
, vol.258
, pp. 113-116
-
-
Ikeda, K.1
Akiyama, H.2
Araj, T.3
Kondo, H.4
Haga, C.5
Iritani, S.6
Kuniaki, T.7
-
16
-
-
0035008658
-
Evidence that malondialdehyde-derived aminoenimine is not a fluorescent age pigment
-
Itakura K., and Uchida K. Evidence that malondialdehyde-derived aminoenimine is not a fluorescent age pigment. Chem. Res. Toxicol. 14 (2001) 473-475
-
(2001)
Chem. Res. Toxicol.
, vol.14
, pp. 473-475
-
-
Itakura, K.1
Uchida, K.2
-
17
-
-
0034640337
-
Detection of lipofuscin like fluorophore in oxidized human low-density lipoprotein, 4-hydroxy-2-nonenal as a potential source of fluorescent chromophore
-
Itakura K., Oya-Ito T., Osawa T., Yamada S., Toyokuni S., Shibata N., Kobayashi M., and Uchida K. Detection of lipofuscin like fluorophore in oxidized human low-density lipoprotein, 4-hydroxy-2-nonenal as a potential source of fluorescent chromophore. FEBS Lett. 473 (2000) 249-253
-
(2000)
FEBS Lett.
, vol.473
, pp. 249-253
-
-
Itakura, K.1
Oya-Ito, T.2
Osawa, T.3
Yamada, S.4
Toyokuni, S.5
Shibata, N.6
Kobayashi, M.7
Uchida, K.8
-
18
-
-
0043069764
-
Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration
-
Liou Y.-C., Sun A., Ryo A., Zhou X.Z., Yu Z.-X., Huang H.-K., Uchida T., Bronson R., Bing G., Li X., Hunter T., and Lu K.P. Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration. Nature 424 (2003) 556-561
-
(2003)
Nature
, vol.424
, pp. 556-561
-
-
Liou, Y.-C.1
Sun, A.2
Ryo, A.3
Zhou, X.Z.4
Yu, Z.-X.5
Huang, H.-K.6
Uchida, T.7
Bronson, R.8
Bing, G.9
Li, X.10
Hunter, T.11
Lu, K.P.12
-
19
-
-
1842763560
-
Pinning down cell signalling, cancer and Alzheimer's disease
-
Lu K.P. Pinning down cell signalling, cancer and Alzheimer's disease. Trends Biochem. Sci. 29 (2004) 200-209
-
(2004)
Trends Biochem. Sci.
, vol.29
, pp. 200-209
-
-
Lu, K.P.1
-
20
-
-
0029916122
-
A human peptidyl-prolyl isomerase essential for regulation of mitosis
-
Lu K.P., Hanes S.D., and Hunter T. A human peptidyl-prolyl isomerase essential for regulation of mitosis. Nature 380 (1996) 544-547
-
(1996)
Nature
, vol.380
, pp. 544-547
-
-
Lu, K.P.1
Hanes, S.D.2
Hunter, T.3
-
21
-
-
0033600242
-
The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein
-
Lu P.-J., Wulf G., Zhou X.Z., Davies P., and Lu K.P. The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein. Nature 399 (1999) 784-788
-
(1999)
Nature
, vol.399
, pp. 784-788
-
-
Lu, P.-J.1
Wulf, G.2
Zhou, X.Z.3
Davies, P.4
Lu, K.P.5
-
22
-
-
0036535975
-
Pinning down proline-directed phosphorylation signaling
-
Lu K.P., Liou Y.C., and Zhou X.Z. Pinning down proline-directed phosphorylation signaling. Trends Cell Biol. 12 (2002) 164-172
-
(2002)
Trends Cell Biol.
, vol.12
, pp. 164-172
-
-
Lu, K.P.1
Liou, Y.C.2
Zhou, X.Z.3
-
23
-
-
0018139415
-
The quantitative assessment of lipofuscin pigment, cytoplasmic RNA and nucleolar volume in senile dementia
-
Mann D.M.A., and Sinclair K.G.A. The quantitative assessment of lipofuscin pigment, cytoplasmic RNA and nucleolar volume in senile dementia. Neuropathol. Appl. Neurobiol. 4 (1978) 129-135
-
(1978)
Neuropathol. Appl. Neurobiol.
, vol.4
, pp. 129-135
-
-
Mann, D.M.A.1
Sinclair, K.G.A.2
-
24
-
-
27944473999
-
Neuronal intranuclear inclusions are ultrastructurally and immunologically distinct from cytoplasmic inclusions of neuronal intermediate filament inclusion disease (NIFID)
-
Mosaheb S., Thorpe J.R., Hashemzadeh-Bonehi L., Bigio E.H., Gearing M., and Cairns N.J. Neuronal intranuclear inclusions are ultrastructurally and immunologically distinct from cytoplasmic inclusions of neuronal intermediate filament inclusion disease (NIFID). Acta Neuropathol. 110 (2005) 360-368
-
(2005)
Acta Neuropathol.
, vol.110
, pp. 360-368
-
-
Mosaheb, S.1
Thorpe, J.R.2
Hashemzadeh-Bonehi, L.3
Bigio, E.H.4
Gearing, M.5
Cairns, N.J.6
-
25
-
-
0031022255
-
Increased expression of cathepsin E and D in neurons of the aged rat brain and their colocalization with lipofuscin and carboxy-terminal fragments of Alzheimer amyloid precursor protein
-
Nakanishi H., Amano T., Sastradipura D.F., Yoshimine Y., Tsukuba T., Tanabe K., Hirostu I., Ohono T., and Yamamoto K. Increased expression of cathepsin E and D in neurons of the aged rat brain and their colocalization with lipofuscin and carboxy-terminal fragments of Alzheimer amyloid precursor protein. J. Neurochem. 68 (1997) 739-749
-
(1997)
J. Neurochem.
, vol.68
, pp. 739-749
-
-
Nakanishi, H.1
Amano, T.2
Sastradipura, D.F.3
Yoshimine, Y.4
Tsukuba, T.5
Tanabe, K.6
Hirostu, I.7
Ohono, T.8
Yamamoto, K.9
-
26
-
-
0034304390
-
The endosomal-lysosomal system of neurons in Alzheimer's disease pathogenesis: a review
-
Nixon R.A., Cataldo A.M., and Mathews P.M. The endosomal-lysosomal system of neurons in Alzheimer's disease pathogenesis: a review. Neurochem. Res. 25 (2000) 1161-1172
-
(2000)
Neurochem. Res.
, vol.25
, pp. 1161-1172
-
-
Nixon, R.A.1
Cataldo, A.M.2
Mathews, P.M.3
-
28
-
-
0025862009
-
Advances in age pigment research
-
Porta E.A. Advances in age pigment research. Arch. Gerontol. Geriatr. 12 (1991) 303-320
-
(1991)
Arch. Gerontol. Geriatr.
, vol.12
, pp. 303-320
-
-
Porta, E.A.1
-
29
-
-
0036241090
-
Pigments in aging: an overview
-
Porta E.A. Pigments in aging: an overview. Ann. N. Y. Acad. Sci. 959 (2002) 57-65
-
(2002)
Ann. N. Y. Acad. Sci.
, vol.959
, pp. 57-65
-
-
Porta, E.A.1
-
30
-
-
0142157635
-
Pin1 colocalization with phosphorylated tau in Alzheimer's disease and other tauopathies
-
Ramakrishnan P., Dickson D.W., and Davies P. Pin1 colocalization with phosphorylated tau in Alzheimer's disease and other tauopathies. Neurobiol. Dis. 14 (2003) 251-264
-
(2003)
Neurobiol. Dis.
, vol.14
, pp. 251-264
-
-
Ramakrishnan, P.1
Dickson, D.W.2
Davies, P.3
-
31
-
-
0033583925
-
Colocalization of VIP with AVP in neurons of the human paraventricular, supraoptic and suprachiasmatic nucleus
-
Romijn H.J., van Uum J.F.M., Emmering J., Goncharuk V., and Buijs R.M. Colocalization of VIP with AVP in neurons of the human paraventricular, supraoptic and suprachiasmatic nucleus. Brain Res. 832 (1999) 47-53
-
(1999)
Brain Res.
, vol.832
, pp. 47-53
-
-
Romijn, H.J.1
van Uum, J.F.M.2
Emmering, J.3
Goncharuk, V.4
Buijs, R.M.5
-
32
-
-
0033870001
-
Proteosome inhibition by lipofuscin/ceroid during postmitotic aging of fibroblasts
-
Sitte N., Huber M., Grune T., Ladhoff A., Doecke W.D., Von Zglinicki T., and Davies K.J. Proteosome inhibition by lipofuscin/ceroid during postmitotic aging of fibroblasts. FASEB J. 14 (2000) 1490-1498
-
(2000)
FASEB J.
, vol.14
, pp. 1490-1498
-
-
Sitte, N.1
Huber, M.2
Grune, T.3
Ladhoff, A.4
Doecke, W.D.5
Von Zglinicki, T.6
Davies, K.J.7
-
33
-
-
1242307774
-
The peptidyl prolyl cis/trans-isomerase Pin1 recognizes the Phospho-Thr212-Pro213 site on tau
-
Smet C., Sambo A.-V., Wieruszeski J.-M., Leroy A., and Landrieu I. The peptidyl prolyl cis/trans-isomerase Pin1 recognizes the Phospho-Thr212-Pro213 site on tau. Biochemistry-US 43 (2004) 2032-2040
-
(2004)
Biochemistry-US
, vol.43
, pp. 2032-2040
-
-
Smet, C.1
Sambo, A.-V.2
Wieruszeski, J.-M.3
Leroy, A.4
Landrieu, I.5
-
34
-
-
0028037679
-
Quantitative analysis of lipofuscin and neurofibrillary tangles in the hippocampal neurons Alzheimer's disease brains
-
Stojanovic A., Roher A.E., and Ball M.J. Quantitative analysis of lipofuscin and neurofibrillary tangles in the hippocampal neurons Alzheimer's disease brains. Dementia 5 (1994) 229-233
-
(1994)
Dementia
, vol.5
, pp. 229-233
-
-
Stojanovic, A.1
Roher, A.E.2
Ball, M.J.3
-
35
-
-
33745273903
-
-
Sultana, R., Boyd-Kimball, D., Poon, H.F., Cai, J., Pierce, W.M., Klein, J.B., Markesbery, W.R., Zhou, X.Z., Lu, K.P., Butterfield, D.A., in press. Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: a redox proteomics analysis. Neurobiol. Aging.
-
-
-
-
36
-
-
0031889998
-
Lipofuscin: mechanisms of formation and increase with age
-
Terman A., and Brunk U.T. Lipofuscin: mechanisms of formation and increase with age. AMPIS 106 (1998) 265-276
-
(1998)
AMPIS
, vol.106
, pp. 265-276
-
-
Terman, A.1
Brunk, U.T.2
-
37
-
-
0036961940
-
Protease inhibition enhances lipofuscin formation
-
(Part IV; Signal Transduction Stress Response, and Aging)
-
Terman A., and Sandberg S. Protease inhibition enhances lipofuscin formation. Ann. N. Y. Acad. Sci. 973 (2002) 309-312 (Part IV; Signal Transduction Stress Response, and Aging)
-
(2002)
Ann. N. Y. Acad. Sci.
, vol.973
, pp. 309-312
-
-
Terman, A.1
Sandberg, S.2
-
38
-
-
0032610303
-
The application of LR gold resin for immunogold labelling
-
Electron Microscopy Methods and Protocols. Hajibagheri M.A. (Ed), Humana Press Inc., USA
-
Thorpe J.R. The application of LR gold resin for immunogold labelling. In: Hajibagheri M.A. (Ed). Electron Microscopy Methods and Protocols. Methods Mol. Biol. Series vol. 117 (1999), Humana Press Inc., USA 99-110
-
(1999)
Methods Mol. Biol. Series
, vol.117
, pp. 99-110
-
-
Thorpe, J.R.1
-
39
-
-
0032714688
-
The binding of a putative and a known chaperone protein revealed by immunogold labelling transmission electron microscopy: a suggested use of chaperones as probes for the distribution of their target proteins
-
Thorpe J.R., Rulten S.L., and Kay J.E. The binding of a putative and a known chaperone protein revealed by immunogold labelling transmission electron microscopy: a suggested use of chaperones as probes for the distribution of their target proteins. J. Histochem. Cytochem. 47 (1999) 1633-1640
-
(1999)
J. Histochem. Cytochem.
, vol.47
, pp. 1633-1640
-
-
Thorpe, J.R.1
Rulten, S.L.2
Kay, J.E.3
-
40
-
-
0035177565
-
Utilising the peptidyl-prolyl cis-trans isomerase Pin1 as a probe of its phosphorylated target proteins: examples of binding to nuclear proteins in a human kidney cell line and to tau in Alzheimer's diseased brain
-
Thorpe J.R., Morley S.J., and Rulten S.L. Utilising the peptidyl-prolyl cis-trans isomerase Pin1 as a probe of its phosphorylated target proteins: examples of binding to nuclear proteins in a human kidney cell line and to tau in Alzheimer's diseased brain. J. Histochem. Cytochem. 49 (2001) 97-108
-
(2001)
J. Histochem. Cytochem.
, vol.49
, pp. 97-108
-
-
Thorpe, J.R.1
Morley, S.J.2
Rulten, S.L.3
-
41
-
-
5144224351
-
Shortfalls in the peptidyl-prolyl cis-trans isomerase protein Pin1 in neurons are associated with frontotemporal dementias
-
Thorpe J.R., Mosaheb S., Hashemzadeh-Bonehi L., Cairns N.J., Kay K.E., Morley S.J., and Rulten S.L. Shortfalls in the peptidyl-prolyl cis-trans isomerase protein Pin1 in neurons are associated with frontotemporal dementias. Neurobiol. Dis. 17 (2004) 237-249
-
(2004)
Neurobiol. Dis.
, vol.17
, pp. 237-249
-
-
Thorpe, J.R.1
Mosaheb, S.2
Hashemzadeh-Bonehi, L.3
Cairns, N.J.4
Kay, K.E.5
Morley, S.J.6
Rulten, S.L.7
-
42
-
-
0033638180
-
Pin1-dependent prolyl isomerisation regulates dephosphorylation of Cdc25C and tau proteins
-
Zhou X.Z., Kops O., Werner A., Lu P.J., Shen M., Stoller G., Kullertz G., Stark M., Fischer G., and Lu K.P. Pin1-dependent prolyl isomerisation regulates dephosphorylation of Cdc25C and tau proteins. Mol. Cell 6 (2000) 873-883
-
(2000)
Mol. Cell
, vol.6
, pp. 873-883
-
-
Zhou, X.Z.1
Kops, O.2
Werner, A.3
Lu, P.J.4
Shen, M.5
Stoller, G.6
Kullertz, G.7
Stark, M.8
Fischer, G.9
Lu, K.P.10
|