-
1
-
-
80053588682
-
Integration-free iPS cells engineered using human artificial chromosome vectors
-
10.1371/journal.pone.0025961 10.1371/journal.pone.0025961 1:CAS:528:DC%2BC3MXhtlOit77L
-
Hiratsuka M, Uno N, Ueda K, Kurosaki H, Imaoka N, Kazuki K, Ueno E, Akakura Y, Katoh M, Osaki M, Kazuki Y, Nakagawa M, Yamanaka S, Oshimura M (2011) Integration-free iPS cells engineered using human artificial chromosome vectors. PLoS ONE 6:e25961. doi: 10.1371/journal.pone.0025961
-
(2011)
PLoS ONE
, vol.6
, pp. 25961
-
-
Hiratsuka, M.1
Uno, N.2
Ueda, K.3
Kurosaki, H.4
Imaoka, N.5
Kazuki, K.6
Ueno, E.7
Akakura, Y.8
Katoh, M.9
Osaki, M.10
Kazuki, Y.11
Nakagawa, M.12
Yamanaka, S.13
Oshimura, M.14
-
2
-
-
63649117317
-
A highly stable and nonintegrated human artificial chromosome (HAC) containing the 2.4 Mb entire human dystrophin gene
-
10.1038/mt.2008.253 10.1038/mt.2008.253 1:CAS:528:DC%2BD1cXhsVWrtLvN
-
Hoshiya H, Kazuki Y, Abe S, Takiguchi M, Kajitani N, Watanabe Y, Yoshino T, Shirayoshi Y, Higaki K, Messina G, Cossu G, Oshimura M (2009) A highly stable and nonintegrated human artificial chromosome (HAC) containing the 2.4 Mb entire human dystrophin gene. Mol Ther 17:309-317. doi: 10.1038/mt.2008.253
-
(2009)
Mol Ther
, vol.17
, pp. 309-317
-
-
Hoshiya, H.1
Kazuki, Y.2
Abe, S.3
Takiguchi, M.4
Kajitani, N.5
Watanabe, Y.6
Yoshino, T.7
Shirayoshi, Y.8
Higaki, K.9
Messina, G.10
Cossu, G.11
Oshimura, M.12
-
3
-
-
0027980680
-
Distribution of CENP-B boxes reflected in CREST centromere antigenic sites on long-range α-satellite DNA arrays of human chromosome 21
-
Ikeno M, Masumoto H, Okazaki T (1994) Distribution of CENP-B boxes reflected in crest centromere antigenic sites on long-range alpha-satellite DNA arrays of human-chromosome-21. Hum Mol Genet 3:1245-1257. doi: 10.1093/hmg/3.8.1245 (Pubitemid 24255455)
-
(1994)
Human Molecular Genetics
, vol.3
, Issue.8
, pp. 1245-1257
-
-
Ikeno, M.1
Masumoto, H.2
Okazaki, T.3
-
4
-
-
82355190093
-
A new chromosome 14-based human artificial chromosome (HAC) vector system for efficient transgene expression in human primary cells
-
10.1016/j.bbrc.2011.10.088 10.1016/j.bbrc.2011.10.088 1:CAS:528:DC%2BC3MXhsFeju7vP
-
Kakeda M, Nagata K, Osawa K, Matsuno H, Hiratsuka M, Sano A, Okazaki A, Shitara S, Nishikawa S, Masuya A, Hata T, Wako S, Osaki M, Kazuki Y, Oshimura M, Tomizuka K (2011) A new chromosome 14-based human artificial chromosome (HAC) vector system for efficient transgene expression in human primary cells. Biochem Biophys Res Commun 415:439-444. doi: 10.1016/j.bbrc.2011.10.088
-
(2011)
Biochem Biophys Res Commun
, vol.415
, pp. 439-444
-
-
Kakeda, M.1
Nagata, K.2
Osawa, K.3
Matsuno, H.4
Hiratsuka, M.5
Sano, A.6
Okazaki, A.7
Shitara, S.8
Nishikawa, S.9
Masuya, A.10
Hata, T.11
Wako, S.12
Osaki, M.13
Kazuki, Y.14
Oshimura, M.15
Tomizuka, K.16
-
5
-
-
77951797214
-
Exploitation of the interaction of measles virus fusogenic envelope proteins with the surface receptor CD46 on human cells for microcell-mediated chromosome transfer
-
10.1186/1472-6750-10-37 10.1186/1472-6750-10-37
-
Katoh M, Kazuki Y, Kazuki K, Kajitani N, Takiguchi M, Nakayama Y, Nakamura T, Oshimura M (2010) Exploitation of the interaction of measles virus fusogenic envelope proteins with the surface receptor CD46 on human cells for microcell-mediated chromosome transfer. BMC Biotechnol 10:37. doi: 10.1186/1472-6750-10-37
-
(2010)
BMC Biotechnol
, vol.10
, pp. 37
-
-
Katoh, M.1
Kazuki, Y.2
Kazuki, K.3
Kajitani, N.4
Takiguchi, M.5
Nakayama, Y.6
Nakamura, T.7
Oshimura, M.8
-
6
-
-
80052401275
-
Human artificial chromosomes for gene delivery and the development of animal models
-
10.1038/mt.2011.136 10.1038/mt.2011.136 1:CAS:528:DC%2BC3MXoslymsro%3D
-
Kazuki Y, Oshimura M (2011) Human artificial chromosomes for gene delivery and the development of animal models. Mol Ther 19:1591-1601. doi: 10.1038/mt.2011.136
-
(2011)
Mol Ther
, vol.19
, pp. 1591-1601
-
-
Kazuki, Y.1
Oshimura, M.2
-
7
-
-
76249112734
-
Complete genetic correction of iPS cells from duchenne muscular dystrophy
-
10.1038/mt.2009.274 10.1038/mt.2009.274 1:CAS:528:DC%2BD1MXhsFamsL7J
-
Kazuki Y, Hiratsuka M, Takiguchi M, Osaki M, Kajitani N, Hoshiya H, Hiramatsu K, Yoshino T, Kazuki K, Ishihara C, Takehara S, Higaki K, Nakagawa M, Takahashi K, Yamanaka S, Oshimura M (2010) Complete genetic correction of iPS cells from duchenne muscular dystrophy. Mol Ther 18:386-393. doi: 10.1038/mt.2009.274
-
(2010)
Mol Ther
, vol.18
, pp. 386-393
-
-
Kazuki, Y.1
Hiratsuka, M.2
Takiguchi, M.3
Osaki, M.4
Kajitani, N.5
Hoshiya, H.6
Hiramatsu, K.7
Yoshino, T.8
Kazuki, K.9
Ishihara, C.10
Takehara, S.11
Higaki, K.12
Nakagawa, M.13
Takahashi, K.14
Yamanaka, S.15
Oshimura, M.16
-
8
-
-
79953772886
-
Refined human artificial chromosome vectors for gene therapy and animal transgenesis
-
10.1038/gt.2010.147 10.1038/gt.2010.147 1:CAS:528:DC%2BC3cXhsVeis7vK
-
Kazuki Y, Hoshiya H, Takiguchi M, Abe S, Iida Y, Osaki M, Katoh M, Hiratsuka M, Shirayoshi Y, Hiramatsu K, Ueno E, Kajitani N, Yoshino T, Kazuki K, Ishihara C, Takehara S, Tsuji S, Ejima F, Toyoda A, Sakaki Y, Larionov V, Kouprina N, Oshimura M (2011) Refined human artificial chromosome vectors for gene therapy and animal transgenesis. Gene Ther 18:384-393. doi: 10.1038/gt.2010.147
-
(2011)
Gene Ther
, vol.18
, pp. 384-393
-
-
Kazuki, Y.1
Hoshiya, H.2
Takiguchi, M.3
Abe, S.4
Iida, Y.5
Osaki, M.6
Katoh, M.7
Hiratsuka, M.8
Shirayoshi, Y.9
Hiramatsu, K.10
Ueno, E.11
Kajitani, N.12
Yoshino, T.13
Kazuki, K.14
Ishihara, C.15
Takehara, S.16
Tsuji, S.17
Ejima, F.18
Toyoda, A.19
Sakaki, Y.20
Larionov, V.21
Kouprina, N.22
Oshimura, M.23
more..
-
9
-
-
84055200818
-
Human artificial chromosome (HAC) vector with a conditional centromere for correction of genetic deficiencies in human cells
-
10.1073/pnas.1114483108 10.1073/pnas.1114483108 1:CAS:528: DC%2BC3MXhs12gtbbP
-
Kim JH, Kononenko A, Erliandri I, Kim TA, Nakano M, Iida Y, Barrett JC, Oshimura M, Masumoto H, Earnshaw WC, Larionov V, Kouprina N (2011) Human artificial chromosome (HAC) vector with a conditional centromere for correction of genetic deficiencies in human cells. Proc Natl Acad Sci USA 108:20048-20053. doi: 10.1073/pnas.1114483108
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 20048-20053
-
-
Kim, J.H.1
Kononenko, A.2
Erliandri, I.3
Kim, T.A.4
Nakano, M.5
Iida, Y.6
Barrett, J.C.7
Oshimura, M.8
Masumoto, H.9
Earnshaw, W.C.10
Larionov, V.11
Kouprina, N.12
-
10
-
-
0024845617
-
Construction of mouse A9 clones containing a single human chromosome tagged with neomycin-resistance gene via microcell fusion
-
Koi M, Shimizu M, Morita H, Yamada H, Oshimura M (1989) Construction of mouse A9 clones containing a single human-chromosome tagged with neomycin-resistance gene via microcell fusion. Jpn J Cancer Res 80:413-418 (Pubitemid 20038129)
-
(1989)
Japanese Journal of Cancer Research
, vol.80
, Issue.5
, pp. 413-418
-
-
Koi, M.1
Shimizu, M.2
Morita, H.3
Yamada, H.4
Oshimura, M.5
-
11
-
-
84876675718
-
A new generation of human artificial chromosomes for functional genomics and gene therapy
-
Kouprina N, Earnshaw WC, Masumoto H, Larionov V (2013) A new generation of human artificial chromosomes for functional genomics and gene therapy. Cell Mol Life Sci 70:1135-1148
-
(2013)
Cell Mol Life Sci
, vol.70
, pp. 1135-1148
-
-
Kouprina, N.1
Earnshaw, W.C.2
Masumoto, H.3
Larionov, V.4
-
12
-
-
80155133626
-
Integration-free and stable expression of FVIII using a human artificial chromosome
-
10.1038/jhg.2011.88 10.1038/jhg.2011.88 1:CAS:528:DC%2BC3MXhtlKitL3O
-
Kurosaki H, Hiratsuka M, Imaoka N, Iida Y, Uno N, Kazuki Y, Ishihara C, Yakura Y, Mimuro J, Sakata Y, Takeya H, Oshimura M (2011) Integration-free and stable expression of FVIII using a human artificial chromosome. J Hum Genet 56:727-733. doi: 10.1038/jhg.2011.88
-
(2011)
J Hum Genet
, vol.56
, pp. 727-733
-
-
Kurosaki, H.1
Hiratsuka, M.2
Imaoka, N.3
Iida, Y.4
Uno, N.5
Kazuki, Y.6
Ishihara, C.7
Yakura, Y.8
Mimuro, J.9
Sakata, Y.10
Takeya, H.11
Oshimura, M.12
-
13
-
-
33645127443
-
Genetic medicines: Treatment strategies for hereditary disorders
-
10.1038/nrg1829 10.1038/nrg1829
-
O'Connor TP, Crystal RG (2006) Genetic medicines: treatment strategies for hereditary disorders. Nat Rev Genet 7:261-276. doi: 10.1038/nrg1829
-
(2006)
Nat Rev Genet
, vol.7
, pp. 261-276
-
-
O'Connor, T.P.1
Crystal, R.G.2
-
14
-
-
27944464729
-
A novel human artificial chromosome vector provides effective cell lineage-specific transgene expression in human mesenchymal stem cells
-
DOI 10.1634/stemcells.2005-0021
-
Ren X, Katoh M, Hoshiya H, Kurimasa A, Inoue T, Ayabe F, Shibata K, Toguchida J, Oshimura M (2005) A novel human artificial chromosome vector provides effective cell lineage-specific transgene expression in human mesenchymal stem cells. Stem Cells 23:1608-1616. doi: 10.1634/stemcells.2005- 0021 (Pubitemid 41741010)
-
(2005)
Stem Cells
, vol.23
, Issue.10
, pp. 1608-1616
-
-
Ren, X.1
Katoh, M.2
Hoshiya, H.3
Kurimasa, A.4
Inoue, T.5
Ayabe, F.6
Shibata, K.7
Toguchida, J.8
Oshimura, M.9
-
15
-
-
14344275376
-
Mice containing a human chromosome 21 model behavioral impairment and cardiac anomalies of Down's syndrome
-
Shinohara T, Tomizuka K, Miyabara S, Takehara S, Kazuki Y, Inoue J, Katoh M, Nakane H, Iino A, Ohguma A, Ikegami S, Inokuchi K, Ishida I, Reeves RH, Oshimura M (2001) Mice containing a human chromosome 21 model behavioral impairment and cardiac anomalies of Down's syndrome. Hum Mol Genet 10:1163-1175. doi: 10.1093/hmg/10.11.1163 (Pubitemid 32487539)
-
(2001)
Human Molecular Genetics
, vol.10
, Issue.11
, pp. 1163-1175
-
-
Shinohara, T.1
Tomizuka, K.2
Miyabara, S.3
Takehara, S.4
Kazuki, Y.5
Inoue, J.6
Katoh, M.7
Nakane, H.8
Iino, A.9
Ohguma, A.10
Ikegami, S.11
Inokuchi, K.12
Ishida, I.13
Reeves, R.H.14
Oshimura, M.15
-
16
-
-
0030965015
-
Functional expression and germline transmission of a human chromosome fragment in chimaeric mice
-
DOI 10.1038/ng0697-133
-
Tomizuka K, Yoshida H, Uejima H, Kugoh H, Sato K, Ohguma A, Hayasaka M, Hanaoka K, Oshimura M, Ishida I (1997) Functional expression and germline transmission of a human chromosome fragment in chimaeric mice. Nat Genet 16:133-143. doi: 10.1038/ng0697-133 (Pubitemid 27240611)
-
(1997)
Nature Genetics
, vol.16
, Issue.2
, pp. 133-143
-
-
Tomizuka, K.1
Yoshida, H.2
Uejima, H.3
Kugoh, H.4
Sato, K.5
Ohguma, A.6
Hayasaka, M.7
Hanaoka, K.8
Oshimura, M.9
Ishida, I.10
-
17
-
-
0034681121
-
Double trans-chromosomic mice: Maintenance of two individual human chromosome fragments containing Ig heavy and κ loci and expression of fully human antibodies
-
DOI 10.1073/pnas.97.2.722
-
Tomizuka K, Shinohara T, Yoshida H, Uejima H, Ohguma A, Tanaka S, Sato K, Oshimura M, Ishida I (2000) Double trans-chromosomic mice: maintenance of two individual human chromosome fragments containing Ig heavy and kappa loci and expression of fully human antibodies. Proc Natl Acad Sci USA 97:722-727. doi: 10.1073/pnas.97.2.722 (Pubitemid 30070376)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.2
, pp. 722-727
-
-
Tomizuka, K.1
Shinohara, T.2
Yoshida, H.3
Uejima, H.4
Ohguma, A.5
Tanaka, S.6
Sato, K.7
Oshimura, M.8
Ishida, I.9
-
18
-
-
79952085508
-
A method for producing transgenic cells using a multi-integrase system on a human artificial chromosome vector
-
10.1371/journal.pone.0017267 10.1371/journal.pone.0017267 1:CAS:528:DC%2BC3MXjtVSqu7c%3D
-
Yamaguchi S, Kazuki Y, Nakayama Y, Nanba E, Oshimura M, Ohbayashi T (2011) A method for producing transgenic cells using a multi-integrase system on a human artificial chromosome vector. PLoS ONE 6:e17267. doi: 10.1371/journal.pone.0017267
-
(2011)
PLoS ONE
, vol.6
, pp. 17267
-
-
Yamaguchi, S.1
Kazuki, Y.2
Nakayama, Y.3
Nanba, E.4
Oshimura, M.5
Ohbayashi, T.6
|