Integration-free and stable expression of FVIII using a human artificial chromosome

Journal of Human Genetics

Volumn 56, Issue 10, 2011, Pages 727-733

  Kurosaki, Hajime ^a,b   Hiratsuka, Masaharu ^b   Imaoka, Natsuko ^a,b   Iida, Yuichi ^a,b   Uno, Narumi ^a,b   Kazuki, Yasuhiro ^a,b   Ishihara, Chie ^a,b,c   Yakura, Yuwna ^c   Mimuro, Jun ^d   Sakata, Youichi ^d   Takeya, Hiroyuki ^c   Oshimura, Mitsuo ^a,b  

^a TOTTORI UNIVERSITY   (Japan)

^b TOTTORI UNIVERSITY   (Japan)

^c TOTTORI UNIVERSITY   (Japan)

^d JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

factor VIII; hemophilia A; human artificial chromosome; microcell mediated chromosome transfer

Indexed keywords

BETA ACTIN; BLOOD CLOTTING FACTOR 8; COMPLEMENTARY DNA; GENE PRODUCT; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE;

ANIMAL CELL; ARTICLE; ARTIFICIAL CHROMOSOME; CELL IMMORTALIZATION; CHO CELL; CONTROLLED STUDY; DNA CONTENT; EPISOME; FVIII GENE; GENE; GENE EXPRESSION; GENE INSERTION; GENE MUTATION; GENE SILENCING; GENE THERAPY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; NONHUMAN; PLASMID; TRANSGENE;

ANIMALS; CELL LINE; CHO CELLS; CHROMOSOMES, ARTIFICIAL, HUMAN; CRICETINAE; CRICETULUS; FACTOR VIII; GENE DOSAGE; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; MESENCHYMAL STEM CELLS; TRANSGENES;

CRICETULUS GRISEUS;

EID: 80155133626     PISSN: 14345161     EISSN: 1435232X     Source Type: Journal    
DOI: 10.1038/jhg.2011.88     Document Type: Article

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