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Volumn 13, Issue 1, 2014, Pages 64-69

The new era for the treatment of psoriasis and psoriatic arthritis: Perspectives and validated strategies

Author keywords

IL 17; IL 23; Psoriasis; Psoriatic arthritis; Th17 cells; Therapeutic targets

Indexed keywords

ABT 122; BRIAKINUMAB; BRODALUMAB; CHEMOKINE RECEPTOR CCR6; CXCL1 CHEMOKINE; CXCL3 CHEMOKINE; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 12; INTERLEUKIN 12P40; INTERLEUKIN 17; INTERLEUKIN 17 RECEPTOR; INTERLEUKIN 17F; INTERLEUKIN 22; INTERLEUKIN 23; INTERLEUKIN 23 RECEPTOR; INTERLEUKIN 23P19; IXEKIZUMAB; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MESSENGER RNA; OSTEOCLAST DIFFERENTIATION FACTOR; PERAKIZUMAB; PLACEBO; RETINOID RELATED ORPHAN RECEPTOR GAMMA; SCH 900117; SECUKINUMAB; STAT3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; USTEKINUMAB;

EID: 84886951567     PISSN: 15689972     EISSN: 18730183     Source Type: Journal    
DOI: 10.1016/j.autrev.2013.08.006     Document Type: Review
Times cited : (46)

References (79)
  • 1
    • 84875258297 scopus 로고    scopus 로고
    • Immunomodulation in psoriatic arthritis: focus on cellular and molecular pathways
    • [Pii: S1568-9972(12)00260]
    • Chimenti M.S., Ballanti E., Perricone C., Cipriani P., Giacomelli R., Perricone R. Immunomodulation in psoriatic arthritis: focus on cellular and molecular pathways. Autoimmun Rev March 2013, 12(5):599-506. [Pii: S1568-9972(12)00260].
    • (2013) Autoimmun Rev , vol.12 , Issue.5 , pp. 599-506
    • Chimenti, M.S.1    Ballanti, E.2    Perricone, C.3    Cipriani, P.4    Giacomelli, R.5    Perricone, R.6
  • 2
    • 84875251601 scopus 로고    scopus 로고
    • Cartilage as a target of autoimmunity: a thin layer
    • Frisenda S., Perricone C., Valesini G. Cartilage as a target of autoimmunity: a thin layer. Autoimmun Rev Mar 2013, 12(5):591-598.
    • (2013) Autoimmun Rev , vol.12 , Issue.5 , pp. 591-598
    • Frisenda, S.1    Perricone, C.2    Valesini, G.3
  • 3
    • 0345099477 scopus 로고    scopus 로고
    • A prospective, clinical and radiological study of early psoriatic arthritis: an early synovitis clinic experience
    • Kane D., Stafford L., Bresnihan B., FitzGerald O. A prospective, clinical and radiological study of early psoriatic arthritis: an early synovitis clinic experience. Rheumatology (Oxford) Dec 2003, 42(12):1460-1468.
    • (2003) Rheumatology (Oxford) , vol.42 , Issue.12 , pp. 1460-1468
    • Kane, D.1    Stafford, L.2    Bresnihan, B.3    FitzGerald, O.4
  • 4
    • 85027944224 scopus 로고    scopus 로고
    • Synovitis in psoriatic arthritis: immunohistochemistry, comparisons with rheumatoid arthritis, and effects of therapy
    • van Kuijk A.W., Tak P.P. Synovitis in psoriatic arthritis: immunohistochemistry, comparisons with rheumatoid arthritis, and effects of therapy. Curr Rheumatol Rep Aug 2011, 13(4):353-359.
    • (2011) Curr Rheumatol Rep , vol.13 , Issue.4 , pp. 353-359
    • van Kuijk, A.W.1    Tak, P.P.2
  • 5
    • 0033039293 scopus 로고    scopus 로고
    • Psoriatic arthritis: a unified concept twenty years on
    • McGonagle D., Conaghan P.G., Emery P. Psoriatic arthritis: a unified concept twenty years on. Arthritis Rheum Jun 1999, 42(6):1080-1086.
    • (1999) Arthritis Rheum , vol.42 , Issue.6 , pp. 1080-1086
    • McGonagle, D.1    Conaghan, P.G.2    Emery, P.3
  • 6
    • 70349564251 scopus 로고    scopus 로고
    • The enthesis organ concept and its relevance to the spondyloarthropathies
    • Benjamin M., McGonagle D. The enthesis organ concept and its relevance to the spondyloarthropathies. Adv Exp Med Biol 2009, 649:57-70.
    • (2009) Adv Exp Med Biol , vol.649 , pp. 57-70
    • Benjamin, M.1    McGonagle, D.2
  • 8
    • 80051671636 scopus 로고    scopus 로고
    • Emerging role for NK cells in the pathogenesis of inflammatory arthropathies
    • Conigliaro P., Scrivo R., Valesini G., Perricone R. Emerging role for NK cells in the pathogenesis of inflammatory arthropathies. Autoimmun Rev Aug 2011, 10(10):577-581.
    • (2011) Autoimmun Rev , vol.10 , Issue.10 , pp. 577-581
    • Conigliaro, P.1    Scrivo, R.2    Valesini, G.3    Perricone, R.4
  • 9
    • 84863462355 scopus 로고    scopus 로고
    • New insights of T cells in the pathogenesis of psoriasis
    • Cai Y., Fleming C., Yan J. New insights of T cells in the pathogenesis of psoriasis. Cell Mol Immunol Jul 2012, 9(4):302-309.
    • (2012) Cell Mol Immunol , vol.9 , Issue.4 , pp. 302-309
    • Cai, Y.1    Fleming, C.2    Yan, J.3
  • 10
    • 0026501836 scopus 로고
    • The role of streptococcal infection in the initiation of guttate psoriasis
    • Telfer N.R., Chalmers R.J., Whale K., Colman G. The role of streptococcal infection in the initiation of guttate psoriasis. Arch Dermatol Jan 1992, 128(1):39-42.
    • (1992) Arch Dermatol , vol.128 , Issue.1 , pp. 39-42
    • Telfer, N.R.1    Chalmers, R.J.2    Whale, K.3    Colman, G.4
  • 11
    • 0034790695 scopus 로고    scopus 로고
    • A comparison of cyclosporine, sulfasalazine, and symptomatic therapy in the treatment of psoriatic arthritis
    • Salvarani C., Macchioni P., Olivieri I., Marchesoni A., Cutolo M., Ferraccioli G., et al. A comparison of cyclosporine, sulfasalazine, and symptomatic therapy in the treatment of psoriatic arthritis. J Rheumatol Oct 2001, 28(10):2274-2282.
    • (2001) J Rheumatol , vol.28 , Issue.10 , pp. 2274-2282
    • Salvarani, C.1    Macchioni, P.2    Olivieri, I.3    Marchesoni, A.4    Cutolo, M.5    Ferraccioli, G.6
  • 13
    • 84863752634 scopus 로고    scopus 로고
    • Complement system in psoriatic arthritis: a useful marker in response prediction and monitoring of anti-TNF treatment
    • Chimenti M.S., Perricone C., Graceffa D., Di Muzio G., Ballanti E., Guarino M.D., et al. Complement system in psoriatic arthritis: a useful marker in response prediction and monitoring of anti-TNF treatment. Clin Exp Rheumatol Jan 2012, 30(1):23-30.
    • (2012) Clin Exp Rheumatol , vol.30 , Issue.1 , pp. 23-30
    • Chimenti, M.S.1    Perricone, C.2    Graceffa, D.3    Di Muzio, G.4    Ballanti, E.5    Guarino, M.D.6
  • 14
    • 84871426949 scopus 로고    scopus 로고
    • T-helper 17 cells: thedriving force of psoriasis and psoriatic arthritis
    • Yoo I.S., Lee J.H., Song S.T., Kim J.H., Lee H.J., Kang S.W. T-helper 17 cells: thedriving force of psoriasis and psoriatic arthritis. Int J Rheum Dis Dec 2012, 15(6):531-537.
    • (2012) Int J Rheum Dis , vol.15 , Issue.6 , pp. 531-537
    • Yoo, I.S.1    Lee, J.H.2    Song, S.T.3    Kim, J.H.4    Lee, H.J.5    Kang, S.W.6
  • 16
    • 80051670470 scopus 로고    scopus 로고
    • Anti-TNFα discontinuation in rheumatoid and psoriatic arthritis: is it possible after disease remission?
    • Chimenti M.S., Graceffa D., Perricone R. Anti-TNFα discontinuation in rheumatoid and psoriatic arthritis: is it possible after disease remission?. Autoimmun Rev Aug 2011, 10(10):636-640.
    • (2011) Autoimmun Rev , vol.10 , Issue.10 , pp. 636-640
    • Chimenti, M.S.1    Graceffa, D.2    Perricone, R.3
  • 17
    • 78649445740 scopus 로고    scopus 로고
    • Psoriatic skin lesions induced by tumor necrosis factor antagonist therapy: clinical features and possible immunopathogenesis
    • Collamer A.N., Battafarano D.F. Psoriatic skin lesions induced by tumor necrosis factor antagonist therapy: clinical features and possible immunopathogenesis. Semin Arthritis Rheum Dec 2010, 40(3):233-240.
    • (2010) Semin Arthritis Rheum , vol.40 , Issue.3 , pp. 233-240
    • Collamer, A.N.1    Battafarano, D.F.2
  • 18
    • 75749129902 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha blockade exacerbates murine psoriasis-like disease by enhancing Th17 function and decreasing expansion of Treg cells
    • Ma H.L., Napierata L., Stedman N., Benoit S., Collins M., Nickerson-Nutter C., et al. Tumor necrosis factor alpha blockade exacerbates murine psoriasis-like disease by enhancing Th17 function and decreasing expansion of Treg cells. Arthritis Rheum Feb 2010, 62(2):430-440.
    • (2010) Arthritis Rheum , vol.62 , Issue.2 , pp. 430-440
    • Ma, H.L.1    Napierata, L.2    Stedman, N.3    Benoit, S.4    Collins, M.5    Nickerson-Nutter, C.6
  • 19
    • 58149166804 scopus 로고    scopus 로고
    • Blockade of tumor necrosis factor in collagen induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells
    • Notley C.A., Inglis J.J., Alzabin S., McCann F.E., McNamee K.E., Williams R.O. Blockade of tumor necrosis factor in collagen induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells. J Exp Med 2008, 205:2491-2497.
    • (2008) J Exp Med , vol.205 , pp. 2491-2497
    • Notley, C.A.1    Inglis, J.J.2    Alzabin, S.3    McCann, F.E.4    McNamee, K.E.5    Williams, R.O.6
  • 20
    • 0036885067 scopus 로고    scopus 로고
    • The lineage decisions of helper T cells
    • Murphy K.M., Reiner S.L. The lineage decisions of helper T cells. Nat Rev Immunol Dec 2002, 2(12):933-944.
    • (2002) Nat Rev Immunol , vol.2 , Issue.12 , pp. 933-944
    • Murphy, K.M.1    Reiner, S.L.2
  • 21
    • 9744265704 scopus 로고    scopus 로고
    • A phase I study evaluating the safety, pharmacokinetics, and clinical response of a human IL-12 p40 antibody in subjects with plaque psoriasis
    • Kauffman C.L., Aria N., Toichi E., McCormick T.S., Cooper K.D., Gottlieb A.B., et al. A phase I study evaluating the safety, pharmacokinetics, and clinical response of a human IL-12 p40 antibody in subjects with plaque psoriasis. J Invest Dermatol Dec 2004, 123(6):1037-1044.
    • (2004) J Invest Dermatol , vol.123 , Issue.6 , pp. 1037-1044
    • Kauffman, C.L.1    Aria, N.2    Toichi, E.3    McCormick, T.S.4    Cooper, K.D.5    Gottlieb, A.B.6
  • 22
    • 36049052516 scopus 로고    scopus 로고
    • Interleukin-12, interleukin-23, and psoriasis: current prospects
    • [Epub 2007 Aug 15]
    • Torti D.C., Feldman S.R. Interleukin-12, interleukin-23, and psoriasis: current prospects. J Am Acad Dermatol Dec 2007, 57(6):1059-1068. [Epub 2007 Aug 15].
    • (2007) J Am Acad Dermatol , vol.57 , Issue.6 , pp. 1059-1068
    • Torti, D.C.1    Feldman, S.R.2
  • 23
    • 23944493698 scopus 로고    scopus 로고
    • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. 1986
    • J 1
    • Mosmann T.R., Cherwinski H., Bond M.W., Giedlin M.A., Coffman R.L. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. 1986. J Immunol Jul 1 2005, 175(1):5-14.
    • (2005) J Immunol , vol.175 , Issue.1 , pp. 5-14
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 24
    • 27544490377 scopus 로고    scopus 로고
    • Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    • Harrington L.E., Hatton R.D., Mangan P.R., Turner H., Murphy T.L., Murphy K.M., et al. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol Nov 2005, 6(11):1123-1132.
    • (2005) Nat Immunol , vol.6 , Issue.11 , pp. 1123-1132
    • Harrington, L.E.1    Hatton, R.D.2    Mangan, P.R.3    Turner, H.4    Murphy, T.L.5    Murphy, K.M.6
  • 25
    • 27544465354 scopus 로고    scopus 로고
    • A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
    • Park H., Li Z., Yang X.O., Chang S.H., Nurieva R., Wang Y.H., et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol Nov 2005, 6(11):1133-1141.
    • (2005) Nat Immunol , vol.6 , Issue.11 , pp. 1133-1141
    • Park, H.1    Li, Z.2    Yang, X.O.3    Chang, S.H.4    Nurieva, R.5    Wang, Y.H.6
  • 26
    • 84879503193 scopus 로고    scopus 로고
    • Role of IL-17 in psoriasis and psoriatic arthritis
    • Raychaudhuri S.P. Role of IL-17 in psoriasis and psoriatic arthritis. Clin Rev Allergy Immunol Apr 2013, 44(2):183-193.
    • (2013) Clin Rev Allergy Immunol , vol.44 , Issue.2 , pp. 183-193
    • Raychaudhuri, S.P.1
  • 28
    • 34249079176 scopus 로고    scopus 로고
    • Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells
    • [Epub 2007 May 7]
    • Acosta-Rodriguez E.V., Rivino L., Geginat J., Jarrossay D., Gattorno M., Lanzavecchia A., et al. Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells. Nat Immunol Jun 2007, 8(6):639-646. [Epub 2007 May 7].
    • (2007) Nat Immunol , vol.8 , Issue.6 , pp. 639-646
    • Acosta-Rodriguez, E.V.1    Rivino, L.2    Geginat, J.3    Jarrossay, D.4    Gattorno, M.5    Lanzavecchia, A.6
  • 29
    • 34848821989 scopus 로고    scopus 로고
    • Distinct regulation of interleukin-17 in human T helper lymphocytes
    • Chen Z., Tato C.M., Muul L., Laurence A., O'Shea J.J. Distinct regulation of interleukin-17 in human T helper lymphocytes. Arthritis Rheum Sep 2007, 56(9):2936-2946.
    • (2007) Arthritis Rheum , vol.56 , Issue.9 , pp. 2936-2946
    • Chen, Z.1    Tato, C.M.2    Muul, L.3    Laurence, A.4    O'Shea, J.J.5
  • 30
    • 36749081557 scopus 로고    scopus 로고
    • Optimal induction of T helper 17 cells in humans requires T cell receptor ligation in the context of Toll-like receptor-activated monocytes
    • Evans H.G., Suddason T., Jackson I., Taams L.S., Lord G.M. Optimal induction of T helper 17 cells in humans requires T cell receptor ligation in the context of Toll-like receptor-activated monocytes. Proc Natl Acad Sci U S A 2007, 104:17034-17039.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 17034-17039
    • Evans, H.G.1    Suddason, T.2    Jackson, I.3    Taams, L.S.4    Lord, G.M.5
  • 31
    • 34548125305 scopus 로고    scopus 로고
    • Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells
    • Acosta-Rodriguez E.V., Napolitani G., Lanzavecchia A., Sallusto F. Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells. Nat Immunol 2007, 8:942-949.
    • (2007) Nat Immunol , vol.8 , pp. 942-949
    • Acosta-Rodriguez, E.V.1    Napolitani, G.2    Lanzavecchia, A.3    Sallusto, F.4
  • 32
    • 34548133583 scopus 로고    scopus 로고
    • Development, cytokine profile and function of human interleukin 17-producing helper T cells
    • Wilson N.J., et al. Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat Immunol 2007, 8:950-957.
    • (2007) Nat Immunol , vol.8 , pp. 950-957
    • Wilson, N.J.1
  • 33
    • 35348948374 scopus 로고    scopus 로고
    • Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells
    • van Beelen A.J., et al. Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells. Immunity 2007, 27:660-669.
    • (2007) Immunity , vol.27 , pp. 660-669
    • van Beelen, A.J.1
  • 34
    • 44049104564 scopus 로고    scopus 로고
    • The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγT
    • [Author manuscript; available in PMC]
    • Manel Nicolas, Unutmaz Derya, Littman Dan R. The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγT. Nat Immunol June 2008, 9(6):641-649. [Author manuscript; available in PMC].
    • (2008) Nat Immunol , vol.9 , Issue.6 , pp. 641-649
    • Manel, N.1    Unutmaz, D.2    Littman, D.R.3
  • 35
    • 51349111163 scopus 로고    scopus 로고
    • An overview of IL-17 function and signaling
    • [Epub 2008 Aug 12]
    • Gaffen S.L. An overview of IL-17 function and signaling. Cytokine Sep 2008, 43(3):402-407. [Epub 2008 Aug 12]. 10.1016/j.cyto.2008.07.017.
    • (2008) Cytokine , vol.43 , Issue.3 , pp. 402-407
    • Gaffen, S.L.1
  • 36
    • 84866564036 scopus 로고    scopus 로고
    • Functional niche of inflamed synovium for Th17-cell expansion and activation in rheumatoid arthritis: implication to clinical therapeutics
    • Dong W., Zhu P. Functional niche of inflamed synovium for Th17-cell expansion and activation in rheumatoid arthritis: implication to clinical therapeutics. Autoimmun Rev Oct 2012, 11(12):844-851.
    • (2012) Autoimmun Rev , vol.11 , Issue.12 , pp. 844-851
    • Dong, W.1    Zhu, P.2
  • 37
    • 38449094307 scopus 로고    scopus 로고
    • Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F
    • O 15
    • Kuestner R.E., Taft D.W., Haran A., Brandt C.S., Brender T., Lum K., et al. Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F. J Immunol Oct 15 2007, 179(8):5462-5473.
    • (2007) J Immunol , vol.179 , Issue.8 , pp. 5462-5473
    • Kuestner, R.E.1    Taft, D.W.2    Haran, A.3    Brandt, C.S.4    Brender, T.5    Lum, K.6
  • 38
    • 30944452780 scopus 로고    scopus 로고
    • Therapeutic efficacy of IL-17 neutralization in murine experimental autoimmune encephalomyelitis
    • [Epub 2005 Dec 28]
    • Hofstetter H.H., Ibrahim S.M., Koczan D., Kruse N., Weishaupt A., Toyka K.V., et al. Therapeutic efficacy of IL-17 neutralization in murine experimental autoimmune encephalomyelitis. Cell Immunol Oct 2005, 237(2):123-130. [Epub 2005 Dec 28].
    • (2005) Cell Immunol , vol.237 , Issue.2 , pp. 123-130
    • Hofstetter, H.H.1    Ibrahim, S.M.2    Koczan, D.3    Kruse, N.4    Weishaupt, A.5    Toyka, K.V.6
  • 39
    • 84870235857 scopus 로고    scopus 로고
    • Th17 and regulatory T lymphocytes in primary biliary cirrhosis and systemic sclerosis as models of autoimmune fibrotic diseases
    • Fenoglio D., Bernuzzi F., Battaglia F., Parodi A., Kalli F., Negrini S., et al. Th17 and regulatory T lymphocytes in primary biliary cirrhosis and systemic sclerosis as models of autoimmune fibrotic diseases. Autoimmun Rev Dec 2012, 12(2):300-304.
    • (2012) Autoimmun Rev , vol.12 , Issue.2 , pp. 300-304
    • Fenoglio, D.1    Bernuzzi, F.2    Battaglia, F.3    Parodi, A.4    Kalli, F.5    Negrini, S.6
  • 40
    • 80054684397 scopus 로고    scopus 로고
    • The dysregulation of cytokine networks in systemic lupus erythematosus
    • [Epub 2011 Aug 30]
    • Apostolidis S.A., Lieberman L.A., Kis-Toth K., Crispín J.C., Tsokos G.C. The dysregulation of cytokine networks in systemic lupus erythematosus. J Interferon Cytokine Res 2011 Oct, 31(10):769-779. [Epub 2011 Aug 30]. 10.1089/jir.2011.0029.
    • (2011) J Interferon Cytokine Res , vol.31 , Issue.10 , pp. 769-779
    • Apostolidis, S.A.1    Lieberman, L.A.2    Kis-Toth, K.3    Crispín, J.C.4    Tsokos, G.C.5
  • 41
    • 84865704333 scopus 로고    scopus 로고
    • IL-17: a new actor in IFN-driven systemic autoimmune diseases
    • Ambrosi A., Espinosa A., Wahren-Herlenius M. IL-17: a new actor in IFN-driven systemic autoimmune diseases. Eur J Immunol Sep 2012, 42(9):2274-2284.
    • (2012) Eur J Immunol , vol.42 , Issue.9 , pp. 2274-2284
    • Ambrosi, A.1    Espinosa, A.2    Wahren-Herlenius, M.3
  • 42
    • 0344585384 scopus 로고    scopus 로고
    • Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice
    • D 1
    • Nakae S., Nambu A., Sudo K., Iwakura Y. Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J Immunol Dec 1 2003, 171(11):6173-6177.
    • (2003) J Immunol , vol.171 , Issue.11 , pp. 6173-6177
    • Nakae, S.1    Nambu, A.2    Sudo, K.3    Iwakura, Y.4
  • 43
    • 0036188478 scopus 로고    scopus 로고
    • Reduction of joint inflammation and bone erosion in rat adjuvant arthritis by treatment with interleukin-17 receptor IgG1 Fc fusion protein
    • Bush K.A., Farmer K.M., Walker J.S., Kirkham B.W. Reduction of joint inflammation and bone erosion in rat adjuvant arthritis by treatment with interleukin-17 receptor IgG1 Fc fusion protein. Arthritis Rheum Mar 2002, 46(3):802-805.
    • (2002) Arthritis Rheum , vol.46 , Issue.3 , pp. 802-805
    • Bush, K.A.1    Farmer, K.M.2    Walker, J.S.3    Kirkham, B.W.4
  • 44
    • 0033926254 scopus 로고    scopus 로고
    • Contribution of interleukin 17 to synovium matrix destruction in rheumatoid arthritis
    • Chabaud M., Garnero P., Dayer J.M., Guerne P.A., Fossiez F., Miossec P. Contribution of interleukin 17 to synovium matrix destruction in rheumatoid arthritis. Cytokine Jul 2000, 12(7):1092-1099.
    • (2000) Cytokine , vol.12 , Issue.7 , pp. 1092-1099
    • Chabaud, M.1    Garnero, P.2    Dayer, J.M.3    Guerne, P.A.4    Fossiez, F.5    Miossec, P.6
  • 45
    • 0035990279 scopus 로고    scopus 로고
    • Interleukin 17 (IL-17) induces collagenase-3 production in human osteoarthritic chondrocytes via AP-1 dependent activation: differential activation of AP-1 members by IL-17 and IL-1beta
    • Benderdour M., Tardif G., Pelletier J.P., Di Battista J.A., Reboul P., Ranger P., et al. Interleukin 17 (IL-17) induces collagenase-3 production in human osteoarthritic chondrocytes via AP-1 dependent activation: differential activation of AP-1 members by IL-17 and IL-1beta. J Rheumatol Jun 2002, 29(6):1262-1272.
    • (2002) J Rheumatol , vol.29 , Issue.6 , pp. 1262-1272
    • Benderdour, M.1    Tardif, G.2    Pelletier, J.P.3    Di Battista, J.A.4    Reboul, P.5    Ranger, P.6
  • 46
    • 0035997484 scopus 로고    scopus 로고
    • Interleukin 17 induces cartilage collagen breakdown: novel synergistic effects in combination with proinflammatory cytokines
    • Koshy P.J., Henderson N., Logan C., Life P.F., Cawston T.E., Rowan A.D. Interleukin 17 induces cartilage collagen breakdown: novel synergistic effects in combination with proinflammatory cytokines. Ann Rheum Dis Aug 2002, 61(8):704-713.
    • (2002) Ann Rheum Dis , vol.61 , Issue.8 , pp. 704-713
    • Koshy, P.J.1    Henderson, N.2    Logan, C.3    Life, P.F.4    Cawston, T.E.5    Rowan, A.D.6
  • 47
    • 34248589191 scopus 로고    scopus 로고
    • Alteration of antigen-independent immunological synapse formation between dendritic cells and CD4+ T cells, in HLA-B27 trnagenic rat: selective impairement of costimulatory molecules engagement, by mature HLA-B27
    • Hacquard-Bouder C., Chimente M.S., Giquel B., Donnadieu E., Fert I., Schmitt A., et al. Alteration of antigen-independent immunological synapse formation between dendritic cells and CD4+ T cells, in HLA-B27 trnagenic rat: selective impairement of costimulatory molecules engagement, by mature HLA-B27. Arthritis and Rheumatism May 2007, 56(5):1478-1489.
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.5 , pp. 1478-1489
    • Hacquard-Bouder, C.1    Chimente, M.S.2    Giquel, B.3    Donnadieu, E.4    Fert, I.5    Schmitt, A.6
  • 48
    • 0032953514 scopus 로고    scopus 로고
    • Predominance of CD8+ T lymphocytes in psoriatic arthritis
    • Costello P., Bresnihan B., O'Farrelly C., FitzGerald O. Predominance of CD8+ T lymphocytes in psoriatic arthritis. J Rheumatol May 1999, 26(5):1117.
    • (1999) J Rheumatol , vol.26 , Issue.5 , pp. 1117
    • Costello, P.1    Bresnihan, B.2    O'Farrelly, C.3    FitzGerald, O.4
  • 49
    • 0033134608 scopus 로고    scopus 로고
    • IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis
    • Kotake S., Udagawa N., Takahashi N., Matsuzaki K., Itoh K., Ishiyama S., et al. IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J Clin Invest May 1999, 103(9):1345-1352.
    • (1999) J Clin Invest , vol.103 , Issue.9 , pp. 1345-1352
    • Kotake, S.1    Udagawa, N.2    Takahashi, N.3    Matsuzaki, K.4    Itoh, K.5    Ishiyama, S.6
  • 50
    • 34249026701 scopus 로고    scopus 로고
    • Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17
    • [Epub 2007 Apr 22]
    • LeibundGut-Landmann S., Gross O., Robinson M.J., Osorio F., Slack E.C., Tsoni S.V., et al. Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17. Nat Immunol Jun 2007, 8(6):630-638. [Epub 2007 Apr 22].
    • (2007) Nat Immunol , vol.8 , Issue.6 , pp. 630-638
    • LeibundGut-Landmann, S.1    Gross, O.2    Robinson, M.J.3    Osorio, F.4    Slack, E.C.5    Tsoni, S.V.6
  • 51
    • 84863697312 scopus 로고    scopus 로고
    • IL-23 induces spondyloarthropathy by acting on ROR-γt+CD3+CD4-CD8-entheseal resident T cells
    • J 1
    • Sherlock J.P., et al. IL-23 induces spondyloarthropathy by acting on ROR-γt+CD3+CD4-CD8-entheseal resident T cells. Nat Med Jul 1 2012, 18(7):1069-1076.
    • (2012) Nat Med , vol.18 , Issue.7 , pp. 1069-1076
    • Sherlock, J.P.1
  • 53
    • 33751546237 scopus 로고    scopus 로고
    • IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis
    • N 27 [Epub 2006 Oct 30]
    • Chan J.R., et al. IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis. J Exp Med Nov 27 2006, 203(12):2577-2587. [Epub 2006 Oct 30].
    • (2006) J Exp Med , vol.203 , Issue.12 , pp. 2577-2587
    • Chan, J.R.1
  • 54
    • 79951512605 scopus 로고    scopus 로고
    • Integrative responses to IL-17 and TNF-α in human keratinocytes account for key inflammatory pathogenic circuits in psoriasis
    • Chiricozzi A., Guttman-Yassky E., Suárez-Fariñas M., Nograles K.E., Tian S., Cardinale I., et al. Integrative responses to IL-17 and TNF-α in human keratinocytes account for key inflammatory pathogenic circuits in psoriasis. J Invest Dermatol Mar 2011, 131(3):677-687.
    • (2011) J Invest Dermatol , vol.131 , Issue.3 , pp. 677-687
    • Chiricozzi, A.1    Guttman-Yassky, E.2    Suárez-Fariñas, M.3    Nograles, K.E.4    Tian, S.5    Cardinale, I.6
  • 55
    • 79952828120 scopus 로고    scopus 로고
    • Development of the IL-12/23 antagonist ustekinumab in psoriasis: past, present, and future perspectives
    • Yeilding N., et al. Development of the IL-12/23 antagonist ustekinumab in psoriasis: past, present, and future perspectives. Ann N Y Acad Sci Mar 2011, 1222:30-39.
    • (2011) Ann N Y Acad Sci , vol.1222 , pp. 30-39
    • Yeilding, N.1
  • 56
    • 43449094043 scopus 로고    scopus 로고
    • Ustekinumab for chronic plaque psoriasis
    • M 17
    • Bartlett B.L., Tyring S.K. Ustekinumab for chronic plaque psoriasis. Lancet May 17 2008, 371(9625):1639-1640.
    • (2008) Lancet , vol.371 , Issue.9625 , pp. 1639-1640
    • Bartlett, B.L.1    Tyring, S.K.2
  • 57
    • 77951605086 scopus 로고    scopus 로고
    • Anti-p40 antibodies ustekinumab and briakinumab: blockade of interleukin-12 and interleukin-23 in the treatment of psoriasis
    • Gandhi M., Alwawi E., Gordon K.B. Anti-p40 antibodies ustekinumab and briakinumab: blockade of interleukin-12 and interleukin-23 in the treatment of psoriasis. Semin Cutan Med Surg Mar 2010, 29(1):48-52.
    • (2010) Semin Cutan Med Surg , vol.29 , Issue.1 , pp. 48-52
    • Gandhi, M.1    Alwawi, E.2    Gordon, K.B.3
  • 58
    • 34648836878 scopus 로고    scopus 로고
    • Modulation of CLA, IL-12R, CD40L, and IL-2Ralpha expression and inhibition of IL-12- and IL-23-induced cytokine secretion by CNTO 1275
    • [Epub 2007 Aug 29]
    • Reddy M., Davis C., Wong J., Marsters P., Pendley C., Prabhakar U. Modulation of CLA, IL-12R, CD40L, and IL-2Ralpha expression and inhibition of IL-12- and IL-23-induced cytokine secretion by CNTO 1275. Cell Immunol May 2007, 247(1):1-11. [Epub 2007 Aug 29].
    • (2007) Cell Immunol , vol.247 , Issue.1 , pp. 1-11
    • Reddy, M.1    Davis, C.2    Wong, J.3    Marsters, P.4    Pendley, C.5    Prabhakar, U.6
  • 59
    • 43449111187 scopus 로고    scopus 로고
    • Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)
    • M 17
    • Leonardi C.L., et al. Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1). Lancet May 17 2008, 371(9625):1665-1674.
    • (2008) Lancet , vol.371 , Issue.9625 , pp. 1665-1674
    • Leonardi, C.L.1
  • 60
    • 33846889522 scopus 로고    scopus 로고
    • A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis
    • F 8
    • Krueger G.G., et al. A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis. N Engl J Med Feb 8 2007, 356(6):580-592.
    • (2007) N Engl J Med , vol.356 , Issue.6 , pp. 580-592
    • Krueger, G.G.1
  • 61
    • 43449139402 scopus 로고    scopus 로고
    • Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)
    • M 17
    • Papp K.A., et al. Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2). Lancet May 17 2008, 371(9625):1675-1684.
    • (2008) Lancet , vol.371 , Issue.9625 , pp. 1675-1684
    • Papp, K.A.1
  • 62
    • 60249084148 scopus 로고    scopus 로고
    • Ustekinumab, a human interleukin 12/23 monoclonal antibody, for psoriatic arthritis: randomised, double-blind, placebo-controlled, crossover trial
    • F 21
    • Gottlieb A., et al. Ustekinumab, a human interleukin 12/23 monoclonal antibody, for psoriatic arthritis: randomised, double-blind, placebo-controlled, crossover trial. Lancet Feb 21 2009, 373(9664):633-640.
    • (2009) Lancet , vol.373 , Issue.9664 , pp. 633-640
    • Gottlieb, A.1
  • 63
    • 84883134297 scopus 로고    scopus 로고
    • Efficacy and safety of ustekinumab in patients with active psoriatic arthritis: 1year results of the phase 3, multicentre, double-blind, placebo-controlled PSUMMIT 1 trial
    • [Pii: S0140-6736(13)60594-2]
    • McInnes I.B., Kavanaugh A. Efficacy and safety of ustekinumab in patients with active psoriatic arthritis: 1year results of the phase 3, multicentre, double-blind, placebo-controlled PSUMMIT 1 trial. Lancet Aug 2013, 328(9894):780-789. [Pii: S0140-6736(13)60594-2].
    • (2013) Lancet , vol.328 , Issue.9894 , pp. 780-789
    • McInnes, I.B.1    Kavanaugh, A.2
  • 64
    • 39649108216 scopus 로고    scopus 로고
    • Safety and efficacy of ABT-874, a fully human interleukin 12/23 monoclonal antibody, in the treatment of moderate to severe chronic plaque psoriasis: results of a randomized, placebo-controlled, phase 2 trial
    • Kimball A.B., et al. Safety and efficacy of ABT-874, a fully human interleukin 12/23 monoclonal antibody, in the treatment of moderate to severe chronic plaque psoriasis: results of a randomized, placebo-controlled, phase 2 trial. Arch Dermatol Feb 2008, 144(2):200-207.
    • (2008) Arch Dermatol , vol.144 , Issue.2 , pp. 200-207
    • Kimball, A.B.1
  • 65
    • 78751580638 scopus 로고    scopus 로고
    • Efficacy and safety of ABT-874, a monoclonal anti-interleukin 12/23 antibody, for the treatment of chronic plaque psoriasis: 36-week observation/retreatment and 60-week open-label extension phases of a randomized phase II trial
    • Kimball A.B., et al. Efficacy and safety of ABT-874, a monoclonal anti-interleukin 12/23 antibody, for the treatment of chronic plaque psoriasis: 36-week observation/retreatment and 60-week open-label extension phases of a randomized phase II trial. J Am Acad Dermatol Feb 2011, 64(2):263-274.
    • (2011) J Am Acad Dermatol , vol.64 , Issue.2 , pp. 263-274
    • Kimball, A.B.1
  • 66
    • 84900485940 scopus 로고    scopus 로고
    • Effects of briakinumab treatment for moderate to severe psoriasis on health-related quality of life and work productivity and activity impairment: results from a randomized phase III study
    • M 17 [Epub ahead of print]
    • Papp K.A. Effects of briakinumab treatment for moderate to severe psoriasis on health-related quality of life and work productivity and activity impairment: results from a randomized phase III study. J Eur Acad Dermatol Venereol May 17 2013, [Epub ahead of print]. 10.1111/jdv.12177.
    • (2013) J Eur Acad Dermatol Venereol
    • Papp, K.A.1
  • 67
    • 80053231181 scopus 로고    scopus 로고
    • Comparison of different IVIg preparations on IL-17 production by human Th17 cells
    • Maddur M.S., Kaveri S.V., Bayry J. Comparison of different IVIg preparations on IL-17 production by human Th17 cells. Autoimmun Rev Oct 2011, 10(12):809-810.
    • (2011) Autoimmun Rev , vol.10 , Issue.12 , pp. 809-810
    • Maddur, M.S.1    Kaveri, S.V.2    Bayry, J.3
  • 68
    • 79960217450 scopus 로고    scopus 로고
    • Psoriasis: from bed to bench and back
    • J 11
    • Garber K. Psoriasis: from bed to bench and back. Nat Biotechnol Jul 11 2011, 29(7):563-566.
    • (2011) Nat Biotechnol , vol.29 , Issue.7 , pp. 563-566
    • Garber, K.1
  • 69
    • 77958072084 scopus 로고    scopus 로고
    • Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis
    • O 6
    • Hueber W., et al. Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis. Sci Transl Med Oct 6 2010, 2(52):52ra72.
    • (2010) Sci Transl Med , vol.2 , Issue.52
    • Hueber, W.1
  • 70
    • 84877603562 scopus 로고    scopus 로고
    • Efficacy and safety of secukinumab in patients with rheumatoid arthritis: a phase II, dose-finding, double-blind, randomised, placebo controlled study
    • J
    • Genovese M.C., et al. Efficacy and safety of secukinumab in patients with rheumatoid arthritis: a phase II, dose-finding, double-blind, randomised, placebo controlled study. Ann Rheum Dis Jun 2013, 72(6):863-869.
    • (2013) Ann Rheum Dis , vol.72 , Issue.6 , pp. 863-869
    • Genovese, M.C.1
  • 71
    • 84868680312 scopus 로고    scopus 로고
    • Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial
    • D
    • Hueber W., et al. Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial. Gut Dec 2012, 61(12):1693-1700.
    • (2012) Gut , vol.61 , Issue.12 , pp. 1693-1700
    • Hueber, W.1
  • 72
    • 84873124241 scopus 로고    scopus 로고
    • Efficacy and safety of secukinumab in the treatment of moderate-to-severe plaque psoriasis: a randomized, double-blind, placebo-controlled phase II dose-ranging study
    • F
    • Papp K.A., et al. Efficacy and safety of secukinumab in the treatment of moderate-to-severe plaque psoriasis: a randomized, double-blind, placebo-controlled phase II dose-ranging study. Br J Dermatol Feb 2013, 168(2):412-421.
    • (2013) Br J Dermatol , vol.168 , Issue.2 , pp. 412-421
    • Papp, K.A.1
  • 73
    • 84873168729 scopus 로고    scopus 로고
    • Secukinumab induction and maintenance therapy in moderate-to-severe plaque psoriasis: a randomized, double-blind, placebo-controlled, phase II regimen-finding study
    • Rich P., et al. Secukinumab induction and maintenance therapy in moderate-to-severe plaque psoriasis: a randomized, double-blind, placebo-controlled, phase II regimen-finding study. Br J Dermatol Feb 2013, 168(2):402-411.
    • (2013) Br J Dermatol , vol.168 , Issue.2 , pp. 402-411
    • Rich, P.1
  • 74
    • 84866391313 scopus 로고    scopus 로고
    • Anti-IL-17 receptor antibody AMG 827 leads to rapid clinical response in subjects with moderate to severe psoriasis: results from a phase I, randomized, placebo-controlled trial
    • Papp K.A., et al. Anti-IL-17 receptor antibody AMG 827 leads to rapid clinical response in subjects with moderate to severe psoriasis: results from a phase I, randomized, placebo-controlled trial. J Invest Dermatol Oct 2012, 132(10):2466-2469.
    • (2012) J Invest Dermatol , vol.132 , Issue.10 , pp. 2466-2469
    • Papp, K.A.1
  • 75
    • 84891745207 scopus 로고    scopus 로고
    • Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: a 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial
    • J 29 [Epub ahead of print]
    • McInnes I.B., et al. Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: a 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial. Ann Rheum Dis Jan 29 2013, [Epub ahead of print].
    • (2013) Ann Rheum Dis
    • McInnes, I.B.1
  • 76
    • 84859073115 scopus 로고    scopus 로고
    • Anti-interleukin-17 monoclonal antibody ixekizumab in chronic plaque psoriasis
    • M 29
    • Leonardi C., Matheson R., Zachariae C., Cameron G., Li L., Edson-Heredia E., et al. Anti-interleukin-17 monoclonal antibody ixekizumab in chronic plaque psoriasis. N Engl J Med Mar 29 2012, 366(13):1190-1199.
    • (2012) N Engl J Med , vol.366 , Issue.13 , pp. 1190-1199
    • Leonardi, C.1    Matheson, R.2    Zachariae, C.3    Cameron, G.4    Li, L.5    Edson-Heredia, E.6
  • 77
    • 77950535421 scopus 로고    scopus 로고
    • LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study
    • A
    • Genovese M.C., et al. LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study. Arthritis Rheum Apr 2010, 62(4):929-939.
    • (2010) Arthritis Rheum , vol.62 , Issue.4 , pp. 929-939
    • Genovese, M.C.1
  • 78
  • 79
    • 60649092609 scopus 로고    scopus 로고
    • New biologics for psoriasis and psoriatic arthritis
    • Rozenblit M., et al. New biologics for psoriasis and psoriatic arthritis. Dermatol Ther Jan-Feb 2009, 22(1):56-60.
    • Dermatol Ther
    • Rozenblit, M.1


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