The deviant ATP-binding site of the multidrug efflux pump Pdr5 plays an active role in the transport cycle

Journal of Biological Chemistry

Volumn 288, Issue 42, 2013, Pages 30420-30431

  Furman, Christopher ^a   Mehla, Jitender ^a   Ananthaswamy, Neeti ^a   Arya, Nidhi ^a   Kulesh, Bridget ^a   Kovach, Ildiko ^a   Ambudkar, Suresh V ^b   Golin, John ^a  

^a CATHOLIC UNIVERSITY OF AMERICA   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATP HYDROLYSIS; ATP-ASE ACTIVITY; ATP-BINDING SITE; CONSERVED RESIDUES; MULTIDRUG EFFLUX PUMPS; TRANSPORT ACTIVITY; TRANSPORT CYCLE;

BIOCHEMISTRY; BIOLOGY;

BINDING SITES;

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; ALANINE; PROTEIN PDR5; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CELL MEMBRANE; CONTROLLED STUDY; DNA EXTRACTION; DRUG RESISTANCE; ENZYME ACTIVITY; FUNGAL STRAIN; GEL ELECTROPHORESIS; HYDROLYSIS; MEMBRANE VESICLE; MUTANT; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN TRANSPORT; SITE DIRECTED MUTAGENESIS;

ABC TRANSPORTER; ATPASES; DRUG TRANSPORT; MEMBRANE PROTEINS; MULTIDRUG TRANSPORTERS;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SUBSTITUTION; ATP-BINDING CASSETTE TRANSPORTERS; BINDING SITES; BIOLOGICAL TRANSPORT, ACTIVE; DRUG RESISTANCE, MULTIPLE, FUNGAL; MUTATION, MISSENSE; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84886917035     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.494682     Document Type: Article

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