An oral malaria therapy: Curcumin-loaded lipid-based drug delivery systems combined with β-arteether

Journal of Controlled Release

Volumn 172, Issue 3, 2013, Pages 904-913

  Memvanga, Patrick B ^a,b   Coco, Régis ^a   Préat, Véronique ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b UNIVERSITY OF KINSHASA   (Congo)

Author keywords

arteether; Antimalarial efficacy; Caco 2 cells; Curcumin; Lipid based formulations; Oral delivery

Indexed keywords

ANTIMALARIAL EFFICACIES; CACO-2 CELLS; CURCUMIN; LIPID-BASED FORMULATIONS; ORAL DELIVERY;

BIOCHEMISTRY; DISEASES; SOLUBILITY;

DRUG DELIVERY;

ANTIMALARIAL AGENT; ARTEETHER; CURCUMIN; DIETHYLENE GLYCOL MONOETHYL ETHER; LABRASOL;

ANIMAL EXPERIMENT; ANTIMALARIAL ACTIVITY; ARTICLE; CELL VIABILITY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STABILITY; DRUG TRANSPORT; IC 50; IN VITRO STUDY; LIPID BASED DRUG DELIVERY SYSTEM; LIPOLYSIS; MICELLIZATION; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; SURVIVAL RATE; SURVIVAL TIME;

ANTIMALARIAL EFFICACY; CACO-2 CELLS; CURCUMIN; LIPID-BASED FORMULATIONS; ORAL DELIVERY; Β-ARTEETHER;

ANIMALS; ANTIMALARIALS; ARTEMISININS; CACO-2 CELLS; CURCUMIN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HUMANS; LIPIDS; MALARIA; MICE; PLASMODIUM BERGHEI;

EID: 84886864039     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.09.001     Document Type: Article

References (59)

1. Who Press World Malaria Report 2012
2. World Health Organization Guidelines for the Treatment of Malaria 2010
3. A. Codd, F. Teuscher, D. Kyle, Q. Cheng, and M. Gatton Artemisinin-induced parasite dormancy: a plausible mechanism for treatment failure Malar. J. 10 2011 56
4. B. Witkowski, J. Lelievre, M.J. Lopez Barragan, V. Laurent, X.Z. Su, A. Berry, and F. Benoit-Vical Increased tolerance to artemisinin in Plasmodium falciparum is mediated by a quiescence mechanism Antimicrob. Agents Chemother. 54 2010 1872 1877
5. K.R. Hughes, G.A. Biagini, and A.G. Craig Continued cytoadherence of Plasmodium falciparum infected red blood cells after antimalarial treatment Mol. Biochem. Parasitol. 169 2010 71 78
6. G. Padmanaban, V.A. Nagaraj, and P.N. Rangarajan Artemisinin-based combination with curcumin adds a new dimension to malaria therapy Curr. Sci. 102 2012 704 711
7. L. Cui, J. Miao, and L. Cui Cytotoxic effect of curcumin on malaria parasite Plasmodium falciparum: inhibition of histone acetylation and generation of reactive oxygen species Antimicrob. Agents Chemother. 51 2007 488 494
8. R.C. Reddy, P.G. Vatsala, V.G. Keshamouni, G. Padmanaban, and P.N. Rangarajan Curcumin for malaria therapy Biochem. Biophys. Res. Commun. 326 2005 472 474
9. A. Martinelli, L.A. Rodrigues, and P. Cravo Plasmodium chabaudi: efficacy of artemisinin + curcumin combination treatment on a clone selected for artemisinin resistance in mice Exp. Parasitol. 119 2008 304 307
10. D.N. Nandakumar, V.A. Nagaraj, P.G. Vathsala, P. Rangarajan, and G. Padmanaban Curcumin-artemisinin combination therapy for malaria Antimicrob. Agents Chemother. 50 2006 1859 1860
11. P.G. Vathsala, C. Dende, V.A. Nagaraj, D. Bhattacharya, G. Das, P.N. Rangarajan, and G. Padmanaban Curcumin-arteether combination therapy of Plasmodium berghei-infected mice prevents recrudescence through immunomodulation PLoS One 7 2012 e29442
12. N.P. Aditya, G. Chimote, K. Gunalan, R. Banerjee, S. Patankar, and B. Madhusudhan Curcuminoids-loaded liposomes in combination with arteether protects against Plasmodium berghei infection in mice Exp. Parasitol. 131 2012 292 299
13. F. Akhtar, M.M. Rizvi, and S.K. Kar Oral delivery of curcumin bound to chitosan nanoparticles cured Plasmodium yoelii infected mice Biotechnol. Adv. 30 2012 310 320
14. A.P. Nayak, W. Tiyaboonchai, S. Patankar, B. Madhusudhan, and E.B. Souto Curcuminoids-loaded lipid nanoparticles: novel approach towards malaria treatment Colloids Surf. B: Biointerfaces 81 2010 263 273
15. J.G. Bilmen, S.Z. Khan, M.H. Javed, and F. Michelangeli Inhibition of the SERCA Ca2 + pumps by curcumin. Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP Eur. J. Biochem. 268 2001 6318 6327
16. B.B. Aggarwal, C. Sundaram, N. Malani, and H. Ichikawa Curcumin: the Indian solid gold Adv. Exp. Med. Biol. 595 2007 1 75
17. P.N. Mimche, D. Taramelli, and L. Vivas The plant-based immunomodulator curcumin as a potential candidate for the development of an adjunctive therapy for cerebral malaria Malar. J. 10 Suppl. 1 2011 S10
18. R. Chakrabarti, P.S. Rawat, B.M. Cooke, R.L. Coppel, and S. Patankar Cellular effects of curcumin on Plasmodium falciparum include disruption of microtubules PLoS One 8 2013 e57302
19. P. Anand, A.B. Kunnumakkara, R.A. Newman, and B.B. Aggarwal Bioavailability of curcumin: problems and promises Mol. Pharm. 4 2007 807 818
20. J. Shaikh, D.D. Ankola, V. Beniwal, D. Singh, and M.N. Kumar Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer Eur. J. Pharm. Sci. 37 2009 223 230
21. K. Ahmed, Y. Li, D.J. McClements, and H. Xiao Nanoemulsion- and emulsion-based delivery systems for curcumin: encapsulation and release properties Food Chem. 132 2012 799 807
22. H. Yu, and Q. Huang Improving the oral bioavailability of curcumin using novel organogel-based nanoemulsions J. Agric. Food Chem. 60 2012 5373 5379
23. K. Desai, Curcumin cyclodextrin combination for preventing or treating various diseases. Patent US 2010/0779103.
24. K. Maiti, K. Mukherjee, A. Gantait, B.P. Saha, and P.K. Mukherjee Curcumin phospholipid complex: preparation, therapeutic evaluation and pharmacokinetic study in rats Int. J. Pharm. 330 2007 155 163
25. S.W. Seo, H.K. Han, M.K. Chun, and H.K. Choi Preparation and pharmacokinetic evaluation of curcumin solid dispersion using Solutol HS15 as a carrier Int. J. Pharm. 424 2012 18 25
26. M.M. Yallapu, M. Jaggi, and S.C. Chauhan Curcumin nanoformulations: a future nanomedicine for cancer Drug Discov. Today 17 2012 71 80
27. J. Cui, B. Yu, Y. Zhao, W. Zhu, H. Li, H. Lou, and G. Zhai Enhancement of oral absorption of curcumin by self-microemulsifying drug delivery systems Int. J. Pharm. 371 2009 148 155
28. S. Setthacheewakul, S. Mahattanadul, N. Phadoongsombut, W. Pichayakorn, and R. Wiwattanapatapee Development and evaluation of self-microemulsifying liquid and pellet formulations of curcumin, and absorption studies in rats Eur. J. Pharm. Biopharm. 76 2010 475 485
29. Y.D. Yan, J.A. Kim, M.K. Kwak, B.K. Yoo, C.S. Yong, and H.G. Choi Enhanced oral bioavailability of curcumin via a solid lipid-based self-emulsifying drug delivery system using a spray-drying technique Biol. Pharm. Bull. 34 2011 1179 1186
30. E. Jantratid, N. Janssen, C. Reppas, and J.B. Dressman Dissolution media simulating conditions in the proximal human gastrointestinal tract: an update Pharm. Res. 25 2008 1663 1676
31. C.J. Porter, and W.N. Charman In vitro assessment of oral lipid based formulations Adv. Drug Deliv. Rev. 50 Suppl. 1 2001 S127 S147
32. G. Krishna, K. Chen, C. Lin, and A.A. Nomeir Permeability of lipophilic compounds in drug discovery using in-vitro human absorption model, Caco-2 Int. J. Pharm. 222 2001 77 89
33. S. Yamashita, T. Furubayashi, M. Kataoka, T. Sakane, H. Sezaki, and H. Tokuda Optimized conditions for prediction of intestinal drug permeability using Caco-2 cells Eur. J. Pharm. Sci. 10 2000 195 204
34. J.F. Cuine, C.L. McEvoy, W.N. Charman, C.W. Pouton, G.A. Edwards, H. Benameur, and C.J. Porter Evaluation of the impact of surfactant digestion on the bioavailability of danazol after oral administration of lipidic self-emulsifying formulations to dogs J. Pharm. Sci. 97 2008 995 1012
35. P.B. Memvanga, and V. Préat Formulation design and in vivo antimalarial evaluation of lipid-based drug delivery systems for oral delivery of beta-arteether Eur. J. Pharm. Biopharm. 82 2012 112 119
36. P.B. Memvanga, P. Eloy, E.M. Gaigneaux, and V. Préat In vitro lipolysis and intestinal transport of beta-arteether-loaded lipid-based drug delivery systems Pharm. Res. 30 2013 2694 2705
37. P.J. Sassene, M.M. Knopp, J.Z. Hesselkilde, V. Koradia, A. Larsen, T. Rades, and A. Mullertz Precipitation of a poorly soluble model drug during in vitro lipolysis: characterization and dissolution of the precipitate J. Pharm. Sci. 99 2010 4982 4991
38. A. des Rieux, E.G. Ragnarsson, E. Gullberg, V. Préat, Y.J. Schneider, and P. Artursson Transport of nanoparticles across an in vitro model of the human intestinal follicle associated epithelium Eur. J. Pharm. Sci. 25 2005 455 465
39. A. des Rieux, V. Fievez, I. Theate, J. Mast, V. Préat, and Y.J. Schneider An improved in vitro model of human intestinal follicle-associated epithelium to study nanoparticle transport by M cells Eur. J. Pharm. Sci. 30 2007 380 391
40. R. Coco, L. Plapied, V. Pourcelle, C. Jerome, D.J. Brayden, Y.J. Schneider, and V. Preat Drug delivery to inflamed colon by nanoparticles: comparison of different strategies Int. J. Pharm. 440 2013 3 12
41. C.F. Chignell, P. Bilski, K.J. Reszka, A.G. Motten, R.H. Sik, and T.A. Dahl Spectral and photochemical properties of curcumin Photochem. Photobiol. 59 1994 295 302
42. G. Vandermeulen, L. Rouxhet, A. Arien, M.E. Brewster, and V. Préat Encapsulation of amphotericin B in poly(ethyleneglycol)-block-poly(É- caprolactone-co-trimethylenecarbonate) polymeric micelles Int. J. Pharm. 309 2006 234 240
43. J.F. Ryley, and W. Peters The antimalarial activity of some quinolone esters Ann. Trop. Med. Parasitol. 64 1970 209 222
44. D.A. Fidock, P.J. Rosenthal, S.L. Croft, R. Brun, and S. Nwaka Antimalarial drug discovery: efficacy models for compound screening Nat. Rev. Drug Discov. 3 2004 509 520
45. N.M. Carballeira New advances in fatty acids as antimalarial, antimycobacterial and antifungal agents Prog. Lipid Res. 47 2008 50 61
46. M. Krugliak, E. Deharo, G. Shalmiev, M. Sauvain, C. Moretti, and H. Ginsburg Antimalarial effects of C18 fatty acids on Plasmodium falciparum in culture and on Plasmodium vinckei petteri and Plasmodium yoelii nigeriensis in vivo Exp. Parasitol. 81 1995 97 105
47. L.M. Kumaratilake, B.S. Robinson, A. Ferrante, and A. Poulos Antimalarial properties of n-3 and n-6 polyunsaturated fatty acids: in vitro effects on Plasmodium falciparum and in vivo effects on P. berghei J. Clin. Invest. 89 1992 961 967
48. W. Li, S. Yi, Z. Wang, S. Chen, S. Xin, J. Xie, and C. Zhao Self-nanoemulsifying drug delivery system of persimmon leaf extract: optimization and bioavailability studies Int. J. Pharm. 420 2011 161 171
49. J.L. Delongeas, G.V. de Conchard, A. Beamonte, H. Bertheux, C. Spire, C. Maisonneuve, N. Becourt-Lhote, F. Goldfain-Blanc, and N. Claude Assessment of Labrasol/Labrafil/Transcutol (4/4/2, v/v/v) as a non-clinical vehicle for poorly water-soluble compounds after 4-week oral toxicity study in Wistar rats Regul. Toxicol. Pharmacol. 57 2010 284 290
50. B. Wahlang, Y.B. Pawar, and A.K. Bansal Identification of permeability-related hurdles in oral delivery of curcumin using the Caco-2 cell model Eur. J. Pharm. Biopharm. 77 2011 275 282
51. M.H. Leung, and T.W. Kee Effective stabilization of curcumin by association to plasma proteins: human serum albumin and fibrinogen Langmuir 25 2009 5773 5777
52. N. Thomas, R. Holm, A. Mullertz, and T. Rades In vitro and in vivo performance of novel supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS) J. Control. Release 160 2012 25 32
53. N. Thomas, R. Holm, M. Garmer, J.J. Karlsson, A. Mullertz, and T. Rades Supersaturated self-nanoemulsifying drug delivery systems (Super-SNEDDS) enhance the bioavailability of the poorly water-soluble drug simvastatin in dogs AAPS J. 15 2013 219 227
54. H. Yu, and Q. Huang Investigation of the absorption mechanism of solubilized curcumin using Caco-2 cell monolayers J. Agric. Food Chem. 59 2011 9120 9126
55. X.L. Hou, K. Takahashi, K. Tanaka, K. Tougou, F. Qiu, K. Komatsu, K. Takahashi, and J. Azuma Curcuma drugs and curcumin regulate the expression and function of P-gp in Caco-2 cells in completely opposite ways Int. J. Pharm. 358 2008 224 229
56. K.K. Chereddy, R. Coco, P.B. Memvanga, B. Ucakar, A. des Rieux, G. Vandermeulen, and V. Préat Combined effect of PLGA and curcumin on wound healing activity J. Control. Release 171 2013 208 215
57. M.B. Gangloff, R.P. Glahn, D.D. Miller, and D.R. Van Campen Assessment of iron availability using combined in vitro digestion and Caco-2 cell culture Nutr. Res. 16 1996 479 487
58. D.A. Garrett, M.L. Failla, and R.J. Sarama Development of an in vitro digestion method to assess carotenoid bioavailability from meals J. Agric. Food Chem. 47 1999 4301 4309
59. C. Carrillo, C.M. Del Mar, H. Roelofs, G. Wanten, and S.R. Alonso-Torre Activation of human neutrophils by oleic acid involves the production of reactive oxygen species and a rise in cytosolic calcium concentration: a comparison with N-6 polyunsaturated fatty acids Cell. Physiol. Biochem. 28 2011 329 338