Endothelial nitric oxide synthase phosphorylation at threonine 495 and mitochondrial reactive oxygen species formation in response to a high H 2O2 concentration

Journal of Vascular Research

Volumn 50, Issue 5, 2013, Pages 410-420

  Guterbaum, T J ^a,b   Braunstein, T H ^a,b   Fossum, A ^c   Holstein Rathlou, N H ^a,b   Torp Pedersen, C T ^a,b,d   Dominguez H ^a,b,d  

^a DANISH NATIONAL RESEARCH FOUNDATION   (Denmark)

^b Faculty of Health Sciences   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Endothelial cells; Endothelial nitric oxide synthase; ERK; Hydrogen peroxide; Oxidative stress; Reactive oxygen species; ROCK

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE C; PROTEIN KINASE C BETA INHIBITOR; PROTEIN KINASE C INHIBITOR; REACTIVE OXYGEN METABOLITE; RUBOXISTAURIN; THREONINE; ACETYLCYSTEINE; PROTEIN KINASE; ROCK KINASE; UNCLASSIFIED DRUG;

ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MITOCHONDRION; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM; WESTERN BLOTTING; BIOSYNTHESIS; CONCENTRATION (PARAMETERS); OXIDATIVE STRESS; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL;

ACETYLCYSTEINE; BUTADIENES; CELLS, CULTURED; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYDROGEN PEROXIDE; INDOLES; MALEIMIDES; MAP KINASE KINASE KINASES; MITOCHONDRIA; NITRIC OXIDE SYNTHASE TYPE III; NITRILES; PHOSPHORYLATION; PROTEIN KINASE C; REACTIVE OXYGEN SPECIES; RHO-ASSOCIATED KINASES; THREONINE;

EID: 84886802713     PISSN: 10181172     EISSN: 14230135     Source Type: Journal    
DOI: 10.1159/000354225     Document Type: Article

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