-
1
-
-
0025871551
-
Calcium and cAMP activate different chloride channels in the apical membrane of normal and cystic fibrosis epithelia
-
Anderson MP & Welsh MJ (1991). Calcium and cAMP activate different chloride channels in the apical membrane of normal and cystic fibrosis epithelia. Proc Natl Acad Sci U S A 88, 6003-6007.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 6003-6007
-
-
Anderson, M.P.1
Welsh, M.J.2
-
3
-
-
38149091749
-
Calcium homeostasis is abnormal in cystic fibrosis airway epithelial cells but is normalized after rescue of F508del-CFTR
-
Antigny F, Norez C, Becq F & Vandebrouck C (2007). Calcium homeostasis is abnormal in cystic fibrosis airway epithelial cells but is normalized after rescue of F508del-CFTR. Cell Calcium 43, 175-183.
-
(2007)
Cell Calcium
, vol.43
, pp. 175-183
-
-
Antigny, F.1
Norez, C.2
Becq, F.3
Vandebrouck, C.4
-
4
-
-
82655171620
-
2+ entry by increasing plasma membrane insertion of Orai1
-
2+ entry by increasing plasma membrane insertion of Orai1. FASEB J 25, 4274-4291.
-
(2011)
FASEB J
, vol.25
, pp. 4274-4291
-
-
Balghi, H.1
Robert, R.2
Rappaz, B.3
Zhang, X.4
Wohlhuter-Haddad, A.5
Evagelidis, A.6
Luo, Y.7
Goepp, J.8
Ferraro, P.9
Roméo, P.10
Trebak, M.11
Wiseman, P.W.12
Thomas, D.Y.13
Hanrahan, J.W.14
-
5
-
-
14844303317
-
Phosphodiesterase 4D forms a cAMP diffusion barrier at the apical membrane of the airway epithelium
-
Barnes AP, Livera G, Huang P, Sun C, O'Neal WK, Conti M, Stutts MJ & Milgram SL (2005). Phosphodiesterase 4D forms a cAMP diffusion barrier at the apical membrane of the airway epithelium. J Biol Chem 280, 7997-8003.
-
(2005)
J Biol Chem
, vol.280
, pp. 7997-8003
-
-
Barnes, A.P.1
Livera, G.2
Huang, P.3
Sun, C.4
O'Neal, W.K.5
Conti, M.6
Stutts, M.J.7
Milgram, S.L.8
-
7
-
-
14944355539
-
Salivary secretion assay for drug efficacy for cystic fibrosis in mice
-
Best JA & Quinton PM (2005). Salivary secretion assay for drug efficacy for cystic fibrosis in mice. Exp Physiol 90, 189-193.
-
(2005)
Exp Physiol
, vol.90
, pp. 189-193
-
-
Best, J.A.1
Quinton, P.M.2
-
8
-
-
84881253530
-
Role of tyrosine phosphorylation in the muscarinic activation of the cystic fibrosis transmembrane conductance regulator (CFTR)
-
Billet A, Luo Y, Balghi H & Hanrahan JW (2013). Role of tyrosine phosphorylation in the muscarinic activation of the cystic fibrosis transmembrane conductance regulator (CFTR). J Biol Chem 288, 21815-21823.
-
(2013)
J Biol Chem
, vol.288
, pp. 21815-21823
-
-
Billet, A.1
Luo, Y.2
Balghi, H.3
Hanrahan, J.W.4
-
9
-
-
0026786471
-
Regulation of protein serine-threonine phosphatase type-2A by tyrosine phosphorylation
-
Chen J, Martin BL & Brautigan DL (1992). Regulation of protein serine-threonine phosphatase type-2A by tyrosine phosphorylation. Science 257, 1261-1264.
-
(1992)
Science
, vol.257
, pp. 1261-1264
-
-
Chen, J.1
Martin, B.L.2
Brautigan, D.L.3
-
11
-
-
0022558296
-
Calcium-dependent chloride currents in isolated cells from rat lacrimal glands
-
Evans MG & Marty A (1986). Calcium-dependent chloride currents in isolated cells from rat lacrimal glands. J Physiol 378, 437-460.
-
(1986)
J Physiol
, vol.378
, pp. 437-460
-
-
Evans, M.G.1
Marty, A.2
-
12
-
-
70450270621
-
Regulation of TMEM16A chloride channel properties by alternative splicing
-
Ferrera L, Caputo A, Ubby I, Bussani E, Zegarra-Moran O, Ravazzolo R, Pagani F & Galietta LJV (2009). Regulation of TMEM16A chloride channel properties by alternative splicing. J Biol Chem 284, 33360-33368.
-
(2009)
J Biol Chem
, vol.284
, pp. 33360-33368
-
-
Ferrera, L.1
Caputo, A.2
Ubby, I.3
Bussani, E.4
Zegarra-Moran, O.5
Ravazzolo, R.6
Pagani, F.7
Galietta, L.J.V.8
-
13
-
-
0029658263
-
The tyrosine kinase p60c-src regulates the fast gate of the cystic fibrosis transmembrane conductance regulator chloride channel
-
Fischer H & Machen TE (1996). The tyrosine kinase p60c-src regulates the fast gate of the cystic fibrosis transmembrane conductance regulator chloride channel. Biophys J 71, 3073-3082.
-
(1996)
Biophys J
, vol.71
, pp. 3073-3082
-
-
Fischer, H.1
Machen, T.E.2
-
14
-
-
84868126926
-
Physiology of chloride and fluid secretion
-
ed. Riordan JR, Boucher RC & Quinton PM. Cold Spring Harbor Press, Cold Spring, NY, USA
-
Frizzell RA & Hanrahan JW (2012). Physiology of chloride and fluid secretion. In Cystic Fibrosis: Molecular Basis, Physiological Changes, and Therapeutic Strategies, ed. Riordan JR, Boucher RC & Quinton PM. Cold Spring Harbor Press, Cold Spring, NY, USA.
-
(2012)
Cystic Fibrosis: Molecular Basis, Physiological Changes, and Therapeutic Strategies
-
-
Frizzell, R.A.1
Hanrahan, J.W.2
-
17
-
-
84886768934
-
Regulation of the gating of cardiac CFTR Cl channels by phosphorylation and ATP hydrolysis
-
Hwang T-C, Baukrowitz T, Nagel G, Horie M, Nairn AC & Gadsby DC (1994). Regulation of the gating of cardiac CFTR Cl channels by phosphorylation and ATP hydrolysis. J Gen Physiol 104, 34a.
-
(1994)
J Gen Physiol
, vol.104
-
-
Hwang, T.-C.1
Baukrowitz, T.2
Nagel, G.3
Horie, M.4
Nairn, A.C.5
Gadsby, D.C.6
-
18
-
-
64549101142
-
CFTR functions as a bicarbonate channel in pancreatic duct cells
-
Ishiguro H, Steward MC, Naruse S, Ko SB, Goto H, Case RM, Kondo T & Yamamoto A (2009). CFTR functions as a bicarbonate channel in pancreatic duct cells. J Gen Physiol 133, 315-326.
-
(2009)
J Gen Physiol
, vol.133
, pp. 315-326
-
-
Ishiguro, H.1
Steward, M.C.2
Naruse, S.3
Ko, S.B.4
Goto, H.5
Case, R.M.6
Kondo, T.7
Yamamoto, A.8
-
19
-
-
77956354814
-
Hyposecretion of fluid from tracheal submucosal glands of CFTR-deficient pigs
-
Joo NS, Cho H-J, Khansaheb M & Wine JJ (2010). Hyposecretion of fluid from tracheal submucosal glands of CFTR-deficient pigs. J Clin Invest 120, 3161-3166.
-
(2010)
J Clin Invest
, vol.120
, pp. 3161-3166
-
-
Joo, N.S.1
Cho, H.-J.2
Khansaheb, M.3
Wine, J.J.4
-
21
-
-
84864521244
-
- secretion
-
- secretion. Int J Biochem Cell Biol 44, 1897-1900.
-
(2012)
Int J Biochem Cell Biol
, vol.44
, pp. 1897-1900
-
-
Kunzelmann, K.1
Tian, Y.2
Martins, J.R.3
Faria, D.4
Kongsuphol, P.5
Ousingsawat, J.6
Wolf, L.7
Schreiber, R.8
-
22
-
-
79960203340
-
A novel role of protein tyrosine kinase2 in mediating chloride secretion in human airway epithelial cells
-
Liang L, Woodward OM, Chen Z, Cotter R & Guggino WB (2011). A novel role of protein tyrosine kinase2 in mediating chloride secretion in human airway epithelial cells. PloS One 6, e21991.
-
(2011)
PloS One
, vol.6
-
-
Liang, L.1
Woodward, O.M.2
Chen, Z.3
Cotter, R.4
Guggino, W.B.5
-
23
-
-
0031802827
-
Differential regulation of single CFTR channels by PP2C, PP2A, and other phosphatases
-
Luo J, Pato MD, Riordan JR & Hanrahan JW (1998). Differential regulation of single CFTR channels by PP2C, PP2A, and other phosphatases. Am J Physiol Cell Physiol 274, C1397-C1410.
-
(1998)
Am J Physiol Cell Physiol
, vol.274
-
-
Luo, J.1
Pato, M.D.2
Riordan, J.R.3
Hanrahan, J.W.4
-
24
-
-
67651039742
-
- channel functional regulation by phosphorylation of focal adhesion kinase at tyrosine 407 in osmosensitive ion transporting mitochondria rich cells of euryhaline killifish
-
- channel functional regulation by phosphorylation of focal adhesion kinase at tyrosine 407 in osmosensitive ion transporting mitochondria rich cells of euryhaline killifish. J Exp Biol 212, 2365-2377.
-
(2009)
J Exp Biol
, vol.212
, pp. 2365-2377
-
-
Marshall, W.S.1
Watters, K.D.2
Hovdestad, L.R.3
Cozzi, R.R.4
Katoh, F.5
-
25
-
-
80052869614
-
- conductance in cystic fibrosis
-
- conductance in cystic fibrosis. Biochim Biophys Acta 1812, 1385-1392.
-
(2011)
Biochim Biophys Acta
, vol.1812
, pp. 1385-1392
-
-
Martins, J.R.1
Kongsuphol, P.2
Sammels, E.3
Dahimene, S.4
Aldehni, F.5
Clarke, L.A.6
Schreiber, R.7
de Smedt, H.8
Amaral, M.D.9
Kunzelmann, K.10
-
26
-
-
84861362217
-
CFTR regulation in human airway epithelial cells requires integrity of the actin cytoskeleton and compartmentalized cAMP and PKA activity
-
Monterisi S, Favia M, Guerra L, Cardone RA, Marzulli D, Reshkin SJ, Casavola V & Zaccolo M (2012). CFTR regulation in human airway epithelial cells requires integrity of the actin cytoskeleton and compartmentalized cAMP and PKA activity. J Cell Sci 125, 1106-1117.
-
(2012)
J Cell Sci
, vol.125
, pp. 1106-1117
-
-
Monterisi, S.1
Favia, M.2
Guerra, L.3
Cardone, R.A.4
Marzulli, D.5
Reshkin, S.J.6
Casavola, V.7
Zaccolo, M.8
-
27
-
-
0037414638
-
- transport in pancreatic duct cells
-
- transport in pancreatic duct cells. J BiolChem 278, 200-207.
-
(2003)
J BiolChem
, vol.278
, pp. 200-207
-
-
Namkung, W.1
Lee, J.A.2
Ahn, W.3
Han, W.4
Kwan, S.W.5
Ahn, D.S.6
Kim, K.H.7
Lee, M.G.8
-
28
-
-
78751478642
-
TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells
-
Namkung W, Phuan P-W & Verkman AS (2011). TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells. J Biol Chem 286, 2365-2374.
-
(2011)
J Biol Chem
, vol.286
, pp. 2365-2374
-
-
Namkung, W.1
Phuan, P.-W.2
Verkman, A.S.3
-
29
-
-
84879492181
-
2+ and cAMP signaling pathways during epithelial transport in mice
-
2+ and cAMP signaling pathways during epithelial transport in mice. Gastroenterology 145, 232-241.
-
(2013)
Gastroenterology
, vol.145
, pp. 232-241
-
-
Park, S.1
Shcheynikov, N.2
Hong, J.H.3
Zheng, C.4
Suh, S.H.5
Kawaai, K.6
Ando, H.7
Mizutani, A.8
Abe, T.9
Kiyanari, H.10
Seki, G.11
Yule, D.12
Mikoshiba, K.13
Muallem, S.14
-
30
-
-
77949472038
-
Compartmentalized cyclic adenosine 3′,5′-monophosphate at the plasma membrane clusters PDE3A and cystic fibrosis transmembrane conductance regulator into microdomains
-
Penmatsu H, Zhang W, Yarlagadda S, Li C, Conoley VG, Yue J, Bahouth SW, Guddington RK, Zhang G, Nelson DJ, Sonecha MD, Manganiello V, Wine JJ & Naren AP (2010). Compartmentalized cyclic adenosine 3′, 5′-monophosphate at the plasma membrane clusters PDE3A and cystic fibrosis transmembrane conductance regulator into microdomains. Mol Biol Cell 21, 1097-1110.
-
(2010)
Mol Biol Cell
, vol.21
, pp. 1097-1110
-
-
Penmatsu, H.1
Zhang, W.2
Yarlagadda, S.3
Li, C.4
Conoley, V.G.5
Yue, J.6
Bahouth, S.W.7
Guddington, R.K.8
Zhang, G.9
Nelson, D.J.10
Sonecha, M.D.11
Manganiello, V.12
Wine, J.J.13
Naren, A.P.14
-
31
-
-
0021271891
-
Defective beta adrenergic response of cystic fibrosis sweat glands in vivo and in vitro
-
Sato K & Sato F (1984). Defective beta adrenergic response of cystic fibrosis sweat glands in vivo and in vitro. J Clin Invest 73, 1763-1771.
-
(1984)
J Clin Invest
, vol.73
, pp. 1763-1771
-
-
Sato, K.1
Sato, F.2
-
32
-
-
0020427480
-
Coexistence of classical transmitters and peptides in the central and peripheral nervous systems
-
Schultzberg M, Hökfelt T & Lundberg JM (1982). Coexistence of classical transmitters and peptides in the central and peripheral nervous systems. Br Med Bull 38, 309-313.
-
(1982)
Br Med Bull
, vol.38
, pp. 309-313
-
-
Schultzberg, M.1
Hökfelt, T.2
Lundberg, J.M.3
-
33
-
-
0032725782
-
Influence of phosphorylation by protein kinase A on CFTR at the cell surface and endoplasmic reticulum
-
Seibert FS, Chang X-B, Aleksandrov AA, Clarke DM, Hanrahan JW & Riordan JR (1999). Influence of phosphorylation by protein kinase A on CFTR at the cell surface and endoplasmic reticulum. Biochim Biophys Acta 1461, 275-283.
-
(1999)
Biochim Biophys Acta
, vol.1461
, pp. 275-283
-
-
Seibert, F.S.1
Chang, X.-B.2
Aleksandrov, A.A.3
Clarke, D.M.4
Hanrahan, J.W.5
Riordan, J.R.6
-
34
-
-
0031450718
-
- secretion
-
- secretion. J Physiol 505, 411-423.
-
(1997)
J Physiol
, vol.505
, pp. 411-423
-
-
Seidler, U.1
Blumenstein, I.2
Kretz, A.3
Viellard-Baron, D.4
Rossmann, H.5
Colledge, W.H.6
Evans, M.7
Ratcliff, R.8
Gregor, M.9
-
35
-
-
84868096271
-
Bicarbonate-dependent chloride transport drives fluid secretion by the human airway epithelial cell line Calu-3
-
Shan J, Liao J, Huang J, Robert R, Palmer ML, Fahrendrug SC, O'Grady SM & Hanrahan JW (2012). Bicarbonate-dependent chloride transport drives fluid secretion by the human airway epithelial cell line Calu-3. J Physiol 590, 5273-5297.
-
(2012)
J Physiol
, vol.590
, pp. 5273-5297
-
-
Shan, J.1
Liao, J.2
Huang, J.3
Robert, R.4
Palmer, M.L.5
Fahrendrug, S.C.6
O'Grady, S.M.7
Hanrahan, J.W.8
-
36
-
-
77956379893
-
Disease phenotype of a ferret CFTR-knockout model of cystic fibrosis
-
Sun X, Sui H, Fisher JT, Yan Z, Liu X, Cho HJ, Joo NS, Zhang Y, Zhou W, Yi Y, Kinyon JM, Lei-Butters DC, Griffin MA, Naumann P, Luo M, Ascher J, Wang K, Frana T, Wine JJ, Meyerholz DK & Engelhardt JF (2010). Disease phenotype of a ferret CFTR-knockout model of cystic fibrosis. J Clin Invest 120, 3149-3160.
-
(2010)
J Clin Invest
, vol.120
, pp. 3149-3160
-
-
Sun, X.1
Sui, H.2
Fisher, J.T.3
Yan, Z.4
Liu, X.5
Cho, H.J.6
Joo, N.S.7
Zhang, Y.8
Zhou, W.9
Yi, Y.10
Kinyon, J.M.11
Lei-Butters, D.C.12
Griffin, M.A.13
Naumann, P.14
Luo, M.15
Ascher, J.16
Wang, K.17
Frana, T.18
Wine, J.J.19
Meyerholz, D.K.20
Engelhardt, J.F.21
more..
-
37
-
-
29244437861
-
The cystic fibrosis transmembrane conductance regulator is regulated by a direct interaction with the protein phosphatase 2A
-
Thelin WR, Kesimer M, Tarran R, Kreda SM, Grubb BR, Sheehan JK, Stutts MJ & Milgram SL (2005). The cystic fibrosis transmembrane conductance regulator is regulated by a direct interaction with the protein phosphatase 2A. J Biol Chem 280, 41512-41520.
-
(2005)
J Biol Chem
, vol.280
, pp. 41512-41520
-
-
Thelin, W.R.1
Kesimer, M.2
Tarran, R.3
Kreda, S.M.4
Grubb, B.R.5
Sheehan, J.K.6
Stutts, M.J.7
Milgram, S.L.8
-
38
-
-
3843101723
-
A small-molecule CFTR inhibitor produces cystic fibrosis-like submucosal gland fluid secretions in normal airways
-
Thiagarajah JR, Song Y, Haggie PM & Verkman AS (2004). A small-molecule CFTR inhibitor produces cystic fibrosis-like submucosal gland fluid secretions in normal airways. FASEB J 18, 875-877.
-
(2004)
FASEB J
, vol.18
, pp. 875-877
-
-
Thiagarajah, J.R.1
Song, Y.2
Haggie, P.M.3
Verkman, A.S.4
-
39
-
-
84868255280
-
Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia
-
Veit G, Bossard F, Goepp J, Verkman AS, Galietta LJ, Hanrahan JW & Lukacs GL (2012). Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia. Mol Biol Cell 23, 4188-4202.
-
(2012)
Mol Biol Cell
, vol.23
, pp. 4188-4202
-
-
Veit, G.1
Bossard, F.2
Goepp, J.3
Verkman, A.S.4
Galietta, L.J.5
Hanrahan, J.W.6
Lukacs, G.L.7
|