F508del-CFTR increases intracellular Ca 2+ signaling that causes enhanced calcium-dependent Cl - conductance in cystic fibrosis

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1812, Issue 11, 2011, Pages 1385-1392

  Martins, Joana Raquel ^a,b   Kongsuphol, Patthara ^a   Sammels, Eva ^d   Dahimène, Shehrazade ^b   AlDehni, Fadi ^a   Clarke, Luka Alexander ^b   Schreiber, Rainer ^a   De Smedt, Humbert ^d   Amaral, Margarida D ^b,c   Kunzelmann, Karl ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b UNIVERSITY OF LISBON   (Portugal)

^c NATIONAL INSTITUTE OF HEALTH DR RICARDO JORGE   (Portugal)

^d UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Bestrophin 1; Ca 2+ activated Cl current; CF inflammation; Cl channel; Purinergic receptor; TMEM16A

Indexed keywords

CALCIUM CHANNEL; CALCIUM ION; CHLORIDE; INOSITOL 1,4,5 TRISPHOSPHATASE; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; SCAVENGER; TRANSMEMBRANE CONDUCTANCE REGULATOR; URIDINE TRIPHOSPHATE;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL LINE; CHLORIDE CONDUCTANCE; CONTROLLED STUDY; CYSTIC FIBROSIS; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; ION CURRENT; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; XENOPUS;

ADENOSYLHOMOCYSTEINASE; ANIMALS; BLOTTING, WESTERN; CALCIUM; CALCIUM SIGNALING; CELLS, CULTURED; CHLORIDE CHANNELS; CHLORIDES; CRICETINAE; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; ENDOPLASMIC RETICULUM; EPITHELIAL CELLS; EYE PROTEINS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOPRECIPITATION; KIDNEY; MEMBRANE PROTEINS; NASAL MUCOSA; NEOPLASM PROTEINS; OOCYTES; SEQUENCE DELETION; XENOPUS LAEVIS;

EID: 80052869614     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2011.08.008     Document Type: Article

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