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Volumn 6, Issue 6, 2013, Pages 1723-1728

Type II cGMP-dependent protein kinase inhibits epidermal growth factor-induced phosphatidylinositol-3-kinase/Akt signal transduction in gastric cancer cells

Author keywords

Apoptosis; Gastric cancer cells; Phosphatidylinositol 3 kinase Akt mediated signal transduction; Type II cGMP dependent protein kinase

Indexed keywords

CASPASE 9; CYCLIC GMP DEPENDENT PROTEIN KINASE 2; EPIDERMAL GROWTH FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B;

EID: 84886801328     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2013.1630     Document Type: Article
Times cited : (17)

References (27)
  • 2
    • 17144395975 scopus 로고    scopus 로고
    • The activation of Akt/PKB signaling pathway and cell survival
    • Song G, Ouyang G and Bao S: The activation of Akt/PKB signaling pathway and cell survival. J Cell Mol Med 9: 59-71, 2005.
    • (2005) J Cell Mol Med , vol.9 , pp. 59-71
    • Song, G.1    Ouyang, G.2    Bao, S.3
  • 3
    • 19944411156 scopus 로고    scopus 로고
    • Inhibiton of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activation, induces apoptosis and delays tumor growth
    • Edward LA, Thiesen B, Dragowska WH, et al: Inhibiton of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activation, induces apoptosis and delays tumor growth. Oncogene 24: 3596-3605, 2005.
    • (2005) Oncogene , vol.24 , pp. 3596-3605
    • Edward, L.A.1    Thiesen, B.2    Dragowska, W.H.3
  • 4
    • 84874180366 scopus 로고    scopus 로고
    • EGFR and downstream genetic alterations in KRAS/BRAF and PI3K/AKT pathways in colorectal cancer: Implications for targeted therapy
    • Berg M and Soreide K: EGFR and downstream genetic alterations in KRAS/BRAF and PI3K/AKT pathways in colorectal cancer: implications for targeted therapy. Discov Med 14: 207-214, 2012.
    • (2012) Discov Med , vol.14 , pp. 207-214
    • Berg, M.1    Soreide, K.2
  • 5
    • 13844273087 scopus 로고    scopus 로고
    • PI3K-Akt pathway: Its functions and alteration in human cancer
    • Osaki M, Oshimura M and Ito H: PI3K-Akt pathway: its functions and alteration in human cancer. Apoptosis 9: 667-676, 2004.
    • (2004) Apoptosis , vol.9 , pp. 667-676
    • Osaki, M.1    Oshimura, M.2    Ito, H.3
  • 6
    • 0031172791 scopus 로고    scopus 로고
    • Characterization of the human gene encoding the type I alpha and type I beta cGMP-dependent protein kinase (PRKG1)
    • Orstavik S, Natarajan V, Taskén K, et al: Characterization of the human gene encoding the type I alpha and type I beta cGMP-dependent protein kinase (PRKG1). Genomics 42: 311-318, 1997.
    • (1997) Genomics , vol.42 , pp. 311-318
    • Orstavik, S.1    Natarajan, V.2    Taskén, K.3
  • 7
    • 0029893239 scopus 로고    scopus 로고
    • Molecular cloning, cDNA structure and chromosomal localization of the human type II cGMP-dependent protein kinase
    • Orstavik S, Solberg R, Taskén K, et al: Molecular cloning, cDNA structure and chromosomal localization of the human type II cGMP-dependent protein kinase. Biochem Biophys Res Commun 220: 759-765, 1996.
    • (1996) Biochem Biophys Res Commun , vol.220 , pp. 759-765
    • Orstavik, S.1    Solberg, R.2    Taskén, K.3
  • 8
    • 41049095471 scopus 로고    scopus 로고
    • Protein kinase G as a therapeutic target for the treatment of metastatic colorectal cancer
    • Browing DD: Protein kinase G as a therapeutic target for the treatment of metastatic colorectal cancer. Expert Opin Ther Targets 12: 367-376, 2008.
    • (2008) Expert Opin Ther Targets , vol.12 , pp. 367-376
    • Browing, D.D.1
  • 9
    • 77950800608 scopus 로고    scopus 로고
    • Expression of cGMP dependent protein kinase II in cancer cell lines was obviously decreased
    • (Medicine Edition)
    • Yang SQ, Chen YC, Wang Y, et al: Expression of cGMP dependent protein kinase II in cancer cell lines was obviously decreased. J Jiangsu Univ (Medicine Edition) 18: 1-5, 2008.
    • (2008) J Jiangsu Univ , vol.18 , pp. 1-5
    • Yang, S.Q.1    Chen, Y.C.2    Wang, Y.3
  • 10
    • 77950845594 scopus 로고    scopus 로고
    • Type II cGMP-dependent protein kinase inhibits proliferation of the gastric cancer cell line BGC-823
    • Chen YC, Ren F, Sang JR, et al: Type II cGMP-dependent protein kinase inhibits proliferation of the gastric cancer cell line BGC-823. Mol Med Rep 3: 361-366, 2010.
    • (2010) Mol Med Rep , vol.3 , pp. 361-366
    • Chen, Y.C.1    Ren, F.2    Sang, J.R.3
  • 11
    • 84862907707 scopus 로고    scopus 로고
    • Type II cGMP-dependent protein kinase inhibits EGF-triggered signal transduction of the MAPK/ERK-mediated pathway in gastric cancer cells
    • Wu Y, Chen Y, Qu R, et al: Type II cGMP-dependent protein kinase inhibits EGF-triggered signal transduction of the MAPK/ERK-mediated pathway in gastric cancer cells. Oncol Rep 27: 553-558, 2012.
    • (2012) Oncol Rep , vol.27 , pp. 553-558
    • Wu, Y.1    Chen, Y.2    Qu, R.3
  • 12
    • 84860785586 scopus 로고    scopus 로고
    • Type II cGMP-dependent protein kinase inhibits EGF-induced MAPK/JNK signal transduction in breast cancer cells
    • Lan T, Chen Y, Sang J, et al: Type II cGMP-dependent protein kinase inhibits EGF-induced MAPK/JNK signal transduction in breast cancer cells. Oncol Rep 27: 2039-2044, 2012.
    • (2012) Oncol Rep , vol.27 , pp. 2039-2044
    • Lan, T.1    Chen, Y.2    Sang, J.3
  • 13
    • 71049146802 scopus 로고    scopus 로고
    • Elevated expression of p53 gain-of-function mutation R175H in endometrial cancer cells can increase the invasive phenotypes by activation of the EGFR/PI3K/AKT pathway
    • Dong P, Xu Z, Jia N, et al: Elevated expression of p53 gain-of-function mutation R175H in endometrial cancer cells can increase the invasive phenotypes by activation of the EGFR/PI3K/AKT pathway. Mol Cancer 8: 103, 2009.
    • (2009) Mol Cancer , vol.8 , pp. 103
    • Dong, P.1    Xu, Z.2    Jia, N.3
  • 15
    • 12844256402 scopus 로고    scopus 로고
    • The biology of cyclic GMP-dependent protein kinases
    • Hofmann F: The biology of cyclic GMP-dependent protein kinases. J Biol Chem 280: 1-4, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 1-4
    • Hofmann, F.1
  • 16
    • 66549111819 scopus 로고    scopus 로고
    • Regulation of epithelial sodium channels by cGMP/PKGII
    • Nie HG, Chen L, Han DY, et al: Regulation of epithelial sodium channels by cGMP/PKGII. J Physiol 587: 2663-2676, 2009.
    • (2009) J Physiol , vol.587 , pp. 2663-2676
    • Nie, H.G.1    Chen, L.2    Han, D.Y.3
  • 17
    • 67649379048 scopus 로고    scopus 로고
    • Type II cGMP-dependent protein kinase mediates osteoblast mechanotransduction
    • Rangaswami H, Marathe N, Zhuang S, et al: Type II cGMP-dependent protein kinase mediates osteoblast mechanotransduction. J Biol Chem 284: 14796-14808, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 14796-14808
    • Rangaswami, H.1    Marathe, N.2    Zhuang, S.3
  • 18
    • 78650674716 scopus 로고    scopus 로고
    • Cyclic GMP and protein kinase G control a Src-containing mechanosome in osteoblasts
    • Rangaswami H, Schwappacher R, Marathe N, et al: Cyclic GMP and protein kinase G control a Src-containing mechanosome in osteoblasts. Sci Signal 3: ra91, 2010.
    • (2010) Sci Signal , vol.3
    • Rangaswami, H.1    Schwappacher, R.2    Marathe, N.3
  • 19
    • 0344014113 scopus 로고    scopus 로고
    • Protein kinase G II-mediated proliferative effects in human cultured prostatic stromal cells
    • Cook AL and Haynes JM: Protein kinase G II-mediated proliferative effects in human cultured prostatic stromal cells. Cell Signal 16: 253-261, 2004.
    • (2004) Cell Signal , vol.16 , pp. 253-261
    • Cook, A.L.1    Haynes, J.M.2
  • 20
    • 69849089410 scopus 로고    scopus 로고
    • Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines
    • Swartling FJ, Ferletta M, Kastemar M, et al: Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines. Oncogene 28: 3121-3131, 2009.
    • (2009) Oncogene , vol.28 , pp. 3121-3131
    • Swartling, F.J.1    Ferletta, M.2    Kastemar, M.3
  • 21
    • 80052441173 scopus 로고    scopus 로고
    • Cyclic GMP induced apoptosis via protein kinase G in oestrogen receptor-positive and-negative breast cancer cell lines
    • Fallahian F, Karami-Tehrani F, Salami S and Aghaei M: Cyclic GMP induced apoptosis via protein kinase G in oestrogen receptor-positive and-negative breast cancer cell lines. FEBS J 278: 3360-3369, 2011.
    • (2011) FEBS J , vol.278 , pp. 3360-3369
    • Fallahian, F.1    Karami-Tehrani, F.2    Salami, S.3    Aghaei, M.4
  • 22
    • 77956173049 scopus 로고    scopus 로고
    • Critical role for the catalytic activity of phospholipase C-γ1 in epidermal growth factor-induced cell migration
    • Xie Z, Peng J, Pennypacker SD and Chen Y: Critical role for the catalytic activity of phospholipase C-γ1 in epidermal growth factor-induced cell migration. Biochem Biophys Res Commun 399: 425-428, 2010.
    • (2010) Biochem Biophys Res Commun , vol.399 , pp. 425-428
    • Xie, Z.1    Peng, J.2    Pennypacker, S.D.3    Chen, Y.4
  • 23
    • 51449095342 scopus 로고    scopus 로고
    • Targeting the PI3K-AKT-mTOR pathway: Progress, pitfalls, and promises
    • Yap TA, Garrett MD, Walton MI, et al: Targeting the PI3K-AKT-mTOR pathway: progress, pitfalls, and promises. Curr Opin Pharmacol 8: 393-412, 2008.
    • (2008) Curr Opin Pharmacol , vol.8 , pp. 393-412
    • Yap, T.A.1    Garrett, M.D.2    Walton, M.I.3
  • 24
    • 1642421130 scopus 로고    scopus 로고
    • Target-based agents against ErbB receptors and their ligands: A novel approach to cancer treatment
    • Normanno N, Bianco C, De Luca A, et al: Target-based agents against ErbB receptors and their ligands: a novel approach to cancer treatment. Endocr Relat Cancer 10: 1-21, 2003.
    • (2003) Endocr Relat Cancer , vol.10 , pp. 1-21
    • Normanno, N.1    Bianco, C.2    De Luca, A.3
  • 25
  • 26
    • 63749086305 scopus 로고    scopus 로고
    • ErbB receptors and signaling pathways in cancer
    • Hynes NE and MacDonald G: ErbB receptors and signaling pathways in cancer. Curr Opin Cell Biol 21: 177-184, 2009.
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 177-184
    • Hynes, N.E.1    McDonald, G.2
  • 27
    • 79954988228 scopus 로고    scopus 로고
    • EGFR tyrosine kinases inhibitors in cancer treatment: In vitro and in vivo evidence
    • Quatrale AE, Porcelli L, Silvestris N, et al: EGFR tyrosine kinases inhibitors in cancer treatment: in vitro and in vivo evidence. Front Biosci 16: 1962-1972, 2011.
    • (2011) Front Biosci , vol.16 , pp. 1962-1972
    • Quatrale, A.E.1    Porcelli, L.2    Silvestris, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.