-
2
-
-
17144395975
-
The activation of Akt/PKB signaling pathway and cell survival
-
Song G, Ouyang G and Bao S: The activation of Akt/PKB signaling pathway and cell survival. J Cell Mol Med 9: 59-71, 2005.
-
(2005)
J Cell Mol Med
, vol.9
, pp. 59-71
-
-
Song, G.1
Ouyang, G.2
Bao, S.3
-
3
-
-
19944411156
-
Inhibiton of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activation, induces apoptosis and delays tumor growth
-
Edward LA, Thiesen B, Dragowska WH, et al: Inhibiton of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activation, induces apoptosis and delays tumor growth. Oncogene 24: 3596-3605, 2005.
-
(2005)
Oncogene
, vol.24
, pp. 3596-3605
-
-
Edward, L.A.1
Thiesen, B.2
Dragowska, W.H.3
-
4
-
-
84874180366
-
EGFR and downstream genetic alterations in KRAS/BRAF and PI3K/AKT pathways in colorectal cancer: Implications for targeted therapy
-
Berg M and Soreide K: EGFR and downstream genetic alterations in KRAS/BRAF and PI3K/AKT pathways in colorectal cancer: implications for targeted therapy. Discov Med 14: 207-214, 2012.
-
(2012)
Discov Med
, vol.14
, pp. 207-214
-
-
Berg, M.1
Soreide, K.2
-
5
-
-
13844273087
-
PI3K-Akt pathway: Its functions and alteration in human cancer
-
Osaki M, Oshimura M and Ito H: PI3K-Akt pathway: its functions and alteration in human cancer. Apoptosis 9: 667-676, 2004.
-
(2004)
Apoptosis
, vol.9
, pp. 667-676
-
-
Osaki, M.1
Oshimura, M.2
Ito, H.3
-
6
-
-
0031172791
-
Characterization of the human gene encoding the type I alpha and type I beta cGMP-dependent protein kinase (PRKG1)
-
Orstavik S, Natarajan V, Taskén K, et al: Characterization of the human gene encoding the type I alpha and type I beta cGMP-dependent protein kinase (PRKG1). Genomics 42: 311-318, 1997.
-
(1997)
Genomics
, vol.42
, pp. 311-318
-
-
Orstavik, S.1
Natarajan, V.2
Taskén, K.3
-
7
-
-
0029893239
-
Molecular cloning, cDNA structure and chromosomal localization of the human type II cGMP-dependent protein kinase
-
Orstavik S, Solberg R, Taskén K, et al: Molecular cloning, cDNA structure and chromosomal localization of the human type II cGMP-dependent protein kinase. Biochem Biophys Res Commun 220: 759-765, 1996.
-
(1996)
Biochem Biophys Res Commun
, vol.220
, pp. 759-765
-
-
Orstavik, S.1
Solberg, R.2
Taskén, K.3
-
8
-
-
41049095471
-
Protein kinase G as a therapeutic target for the treatment of metastatic colorectal cancer
-
Browing DD: Protein kinase G as a therapeutic target for the treatment of metastatic colorectal cancer. Expert Opin Ther Targets 12: 367-376, 2008.
-
(2008)
Expert Opin Ther Targets
, vol.12
, pp. 367-376
-
-
Browing, D.D.1
-
9
-
-
77950800608
-
Expression of cGMP dependent protein kinase II in cancer cell lines was obviously decreased
-
(Medicine Edition)
-
Yang SQ, Chen YC, Wang Y, et al: Expression of cGMP dependent protein kinase II in cancer cell lines was obviously decreased. J Jiangsu Univ (Medicine Edition) 18: 1-5, 2008.
-
(2008)
J Jiangsu Univ
, vol.18
, pp. 1-5
-
-
Yang, S.Q.1
Chen, Y.C.2
Wang, Y.3
-
10
-
-
77950845594
-
Type II cGMP-dependent protein kinase inhibits proliferation of the gastric cancer cell line BGC-823
-
Chen YC, Ren F, Sang JR, et al: Type II cGMP-dependent protein kinase inhibits proliferation of the gastric cancer cell line BGC-823. Mol Med Rep 3: 361-366, 2010.
-
(2010)
Mol Med Rep
, vol.3
, pp. 361-366
-
-
Chen, Y.C.1
Ren, F.2
Sang, J.R.3
-
11
-
-
84862907707
-
Type II cGMP-dependent protein kinase inhibits EGF-triggered signal transduction of the MAPK/ERK-mediated pathway in gastric cancer cells
-
Wu Y, Chen Y, Qu R, et al: Type II cGMP-dependent protein kinase inhibits EGF-triggered signal transduction of the MAPK/ERK-mediated pathway in gastric cancer cells. Oncol Rep 27: 553-558, 2012.
-
(2012)
Oncol Rep
, vol.27
, pp. 553-558
-
-
Wu, Y.1
Chen, Y.2
Qu, R.3
-
12
-
-
84860785586
-
Type II cGMP-dependent protein kinase inhibits EGF-induced MAPK/JNK signal transduction in breast cancer cells
-
Lan T, Chen Y, Sang J, et al: Type II cGMP-dependent protein kinase inhibits EGF-induced MAPK/JNK signal transduction in breast cancer cells. Oncol Rep 27: 2039-2044, 2012.
-
(2012)
Oncol Rep
, vol.27
, pp. 2039-2044
-
-
Lan, T.1
Chen, Y.2
Sang, J.3
-
13
-
-
71049146802
-
Elevated expression of p53 gain-of-function mutation R175H in endometrial cancer cells can increase the invasive phenotypes by activation of the EGFR/PI3K/AKT pathway
-
Dong P, Xu Z, Jia N, et al: Elevated expression of p53 gain-of-function mutation R175H in endometrial cancer cells can increase the invasive phenotypes by activation of the EGFR/PI3K/AKT pathway. Mol Cancer 8: 103, 2009.
-
(2009)
Mol Cancer
, vol.8
, pp. 103
-
-
Dong, P.1
Xu, Z.2
Jia, N.3
-
15
-
-
12844256402
-
The biology of cyclic GMP-dependent protein kinases
-
Hofmann F: The biology of cyclic GMP-dependent protein kinases. J Biol Chem 280: 1-4, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 1-4
-
-
Hofmann, F.1
-
16
-
-
66549111819
-
Regulation of epithelial sodium channels by cGMP/PKGII
-
Nie HG, Chen L, Han DY, et al: Regulation of epithelial sodium channels by cGMP/PKGII. J Physiol 587: 2663-2676, 2009.
-
(2009)
J Physiol
, vol.587
, pp. 2663-2676
-
-
Nie, H.G.1
Chen, L.2
Han, D.Y.3
-
17
-
-
67649379048
-
Type II cGMP-dependent protein kinase mediates osteoblast mechanotransduction
-
Rangaswami H, Marathe N, Zhuang S, et al: Type II cGMP-dependent protein kinase mediates osteoblast mechanotransduction. J Biol Chem 284: 14796-14808, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 14796-14808
-
-
Rangaswami, H.1
Marathe, N.2
Zhuang, S.3
-
18
-
-
78650674716
-
Cyclic GMP and protein kinase G control a Src-containing mechanosome in osteoblasts
-
Rangaswami H, Schwappacher R, Marathe N, et al: Cyclic GMP and protein kinase G control a Src-containing mechanosome in osteoblasts. Sci Signal 3: ra91, 2010.
-
(2010)
Sci Signal
, vol.3
-
-
Rangaswami, H.1
Schwappacher, R.2
Marathe, N.3
-
19
-
-
0344014113
-
Protein kinase G II-mediated proliferative effects in human cultured prostatic stromal cells
-
Cook AL and Haynes JM: Protein kinase G II-mediated proliferative effects in human cultured prostatic stromal cells. Cell Signal 16: 253-261, 2004.
-
(2004)
Cell Signal
, vol.16
, pp. 253-261
-
-
Cook, A.L.1
Haynes, J.M.2
-
20
-
-
69849089410
-
Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines
-
Swartling FJ, Ferletta M, Kastemar M, et al: Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines. Oncogene 28: 3121-3131, 2009.
-
(2009)
Oncogene
, vol.28
, pp. 3121-3131
-
-
Swartling, F.J.1
Ferletta, M.2
Kastemar, M.3
-
21
-
-
80052441173
-
Cyclic GMP induced apoptosis via protein kinase G in oestrogen receptor-positive and-negative breast cancer cell lines
-
Fallahian F, Karami-Tehrani F, Salami S and Aghaei M: Cyclic GMP induced apoptosis via protein kinase G in oestrogen receptor-positive and-negative breast cancer cell lines. FEBS J 278: 3360-3369, 2011.
-
(2011)
FEBS J
, vol.278
, pp. 3360-3369
-
-
Fallahian, F.1
Karami-Tehrani, F.2
Salami, S.3
Aghaei, M.4
-
22
-
-
77956173049
-
Critical role for the catalytic activity of phospholipase C-γ1 in epidermal growth factor-induced cell migration
-
Xie Z, Peng J, Pennypacker SD and Chen Y: Critical role for the catalytic activity of phospholipase C-γ1 in epidermal growth factor-induced cell migration. Biochem Biophys Res Commun 399: 425-428, 2010.
-
(2010)
Biochem Biophys Res Commun
, vol.399
, pp. 425-428
-
-
Xie, Z.1
Peng, J.2
Pennypacker, S.D.3
Chen, Y.4
-
23
-
-
51449095342
-
Targeting the PI3K-AKT-mTOR pathway: Progress, pitfalls, and promises
-
Yap TA, Garrett MD, Walton MI, et al: Targeting the PI3K-AKT-mTOR pathway: progress, pitfalls, and promises. Curr Opin Pharmacol 8: 393-412, 2008.
-
(2008)
Curr Opin Pharmacol
, vol.8
, pp. 393-412
-
-
Yap, T.A.1
Garrett, M.D.2
Walton, M.I.3
-
24
-
-
1642421130
-
Target-based agents against ErbB receptors and their ligands: A novel approach to cancer treatment
-
Normanno N, Bianco C, De Luca A, et al: Target-based agents against ErbB receptors and their ligands: a novel approach to cancer treatment. Endocr Relat Cancer 10: 1-21, 2003.
-
(2003)
Endocr Relat Cancer
, vol.10
, pp. 1-21
-
-
Normanno, N.1
Bianco, C.2
De Luca, A.3
-
26
-
-
63749086305
-
ErbB receptors and signaling pathways in cancer
-
Hynes NE and MacDonald G: ErbB receptors and signaling pathways in cancer. Curr Opin Cell Biol 21: 177-184, 2009.
-
(2009)
Curr Opin Cell Biol
, vol.21
, pp. 177-184
-
-
Hynes, N.E.1
McDonald, G.2
-
27
-
-
79954988228
-
EGFR tyrosine kinases inhibitors in cancer treatment: In vitro and in vivo evidence
-
Quatrale AE, Porcelli L, Silvestris N, et al: EGFR tyrosine kinases inhibitors in cancer treatment: in vitro and in vivo evidence. Front Biosci 16: 1962-1972, 2011.
-
(2011)
Front Biosci
, vol.16
, pp. 1962-1972
-
-
Quatrale, A.E.1
Porcelli, L.2
Silvestris, N.3
|