The combined effects of size and surface chemistry on the accumulation of boronic acid-rich protein nanoparticles in tumors

Biomaterials

Volumn 35, Issue 2, 2014, Pages 866-878

  Wang, Jing ^a   Wu, Wei ^a   Zhang, Yajun ^a   Wang, Xin ^a   Qian, Hanqing ^a   Liu, Baorui ^b   Jiang, Xiqun ^a  

^a NANJING UNIVERSITY   (China)

^b MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

Author keywords

Antitumor activity; Boronic acid; Drug delivery; Polymer nanoparticles

Indexed keywords

ACID-RICH PROTEINS; ANTI-TUMOR ACTIVITIES; BORONIC ACID; BOVINE SERUM ALBUMINS; DRUG DELIVERY SYSTEM; PARTICLE RESIDENCE TIME; POLYMER NANOPARTICLES; RECOGNITION ABILITIES;

BODY FLUIDS; CELL DEATH; DRUG DELIVERY; MAMMALS; NANOPARTICLES; SURFACE CHEMISTRY;

TUMORS;

BORONIC ACID DERIVATIVE; BOVINE SERUM ALBUMIN; BOVINE SERUM ALBUMIN POLY(N 3 ACRYLAMIDOPHENYLBORONIC ACID); COPOLYMER; DOXORUBICIN; MACROGOL; NANOPARTICLE; POLYETHYLENEIMINE; POLYSIALIC ACID; SIALIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER THERAPY; CELL PROLIFERATION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACCUMULATION; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG RELEASE; DRUG UPTAKE; HUMAN; HUMAN CELL; HYDRODYNAMICS; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PARTICLE SIZE; POLYMERIZATION; PRIORITY JOURNAL; SURFACE PROPERTY; TISSUE DISTRIBUTION; TRANSMISSION ELECTRON MICROSCOPY; TUMOR GROWTH; TUMOR VOLUME; ZETA POTENTIAL;

BOVINAE;

ANTITUMOR ACTIVITY; BORONIC ACID; DRUG DELIVERY; POLYMER NANOPARTICLES;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BORONIC ACIDS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; DRUG DELIVERY SYSTEMS; HEP G2 CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; PARTICLE SIZE; PEPTIDES, CYCLIC; POLYETHYLENE GLYCOLS; POLYETHYLENEIMINE; POLYMERS; PROTEIN CONFORMATION; SERUM ALBUMIN, BOVINE; SIALIC ACIDS; SPECTROSCOPY, NEAR-INFRARED;

EID: 84886752329     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.10.028     Document Type: Article

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