The effect of hydrophilic chain length and iRGD on drug delivery from poly(ε-caprolactone)-poly(N-vinylpyrrolidone) nanoparticles

Biomaterials

Volumn 32, Issue 35, 2011, Pages 9525-9535

  Zhu, Zhenshu ^a   Xie, Chen ^a   Liu, Qin ^b   Zhen, Xu ^a   Zheng, Xianchuang ^a   Wu, Wei ^a   Li, Rutian ^b   Ding, Yin ^a   Jiang, Xiqun ^a   Liu, Baorui ^b  

^a NANJING UNIVERSITY   (China)

^b MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

Author keywords

Antitumor; IRGD; Poly(N vinyl pyrrolidone); Tumor penetration

Indexed keywords

ANTI-TUMOR ACTIVITIES; ANTI-TUMORS; BIODISTRIBUTIONS; BLOCK LENGTHS; CAPROLACTONE; CHAIN TRANSFER AGENTS; CIRCULATION TIME; DRUG LOADING; ENCAPSULATION EFFICIENCY; FLUORESCENT DYES; FUNCTIONAL MOIETIES; FUNCTIONALIZED; HOMING PEPTIDE; IN-VITRO; IRGD; LIFE-TIMES; N-VINYL PYRROLIDONE; NANOPARTICLE SURFACE; REVERSE ADDITION; TRANSFER POLYMERIZATION; TUMOR GROWTH; TUMOR PENETRATION; TUMOR SITE; TUMOR TISSUES;

ADSORPTION; ALDEHYDES; COPOLYMERS; DRUG DELIVERY; ENCAPSULATION; FUNCTIONAL POLYMERS; HYDROGELS; TUMORS;

NANOPARTICLES;

ALDEHYDE; ARGINYLGLYCYLASPARTIC ACID; COPOLYMER; FLUORESCENT DYE; HYDROXYL GROUP; IRGD PEPTIDE; NANOPARTICLE; PACLITAXEL; POLY(EPSILON CAPROLACTONE)B(POLY N VINYLPYRROLIDONE); POLYCAPROLACTONE; POVIDONE; UNCLASSIFIED DRUG; XANTHIC ACID DERIVATIVE;

ADSORPTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONJUGATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; HYDROPHILICITY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NANOENCAPSULATION; NONHUMAN; PRIORITY JOURNAL; TUMOR GROWTH;

ADSORPTION; ALPHA-GLOBULINS; ANIMALS; CELL DEATH; CELL LINE; DRUG DELIVERY SYSTEMS; FLUORESCENT ANTIBODY TECHNIQUE; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MALE; MICE; MICE, INBRED ICR; NANOPARTICLES; OLIGOPEPTIDES; PEPTIDES; POLYESTERS; POVIDONE; SERUM ALBUMIN, BOVINE; SPECTROMETRY, FLUORESCENCE; TISSUE DISTRIBUTION; TREATMENT OUTCOME;

MUS;

EID: 80053609371     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.08.072     Document Type: Article

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