Process cost and facility considerations in the selection of primary cell culture clarification technology

Biotechnology Progress

Volumn 29, Issue 5, 2013, Pages 1239-1245

  Felo, Michael ^a   Christensen, Brandon ^b   Higgins, John ^c  

^a MILLIPORE CORPORATION   (United States)

^b MEDIMMUNE   (United States)

^c NOVAVAX INC   (United States)

Author keywords

Centrifugation; Clarification; Cost analysis; Depth filtration; Monoclonal antibody

Indexed keywords

COST ANALYSIS; DEPTH FILTRATION; MONOCLONAL ANTIBODY PRODUCTION; PRIMARY CELL CULTURES; PROTEIN PURIFICATION; SEPARATION TECHNIQUES; TECHNOLOGY SELECTION; THERAPEUTIC PROTEIN;

BIOCONVERSION; BIOREACTORS; CELL CULTURE; CENTRIFUGATION; CLARIFIERS; COST BENEFIT ANALYSIS; COSTS; MONOCLONAL ANTIBODIES; PROTEINS; STAGES; TECHNOLOGY;

CLARIFICATION;

MONOCLONAL ANTIBODY;

AFFINITY CHROMATOGRAPHY; ANIMAL; BIOREACTOR; CENTRIFUGATION; CHO CELL LINE; COMPUTER PROGRAM; COMPUTER SIMULATION; COST; CRICETULUS; ECONOMICS; FILTRATION; METABOLISM; PRIMARY CELL CULTURE; PROCEDURES; THEORETICAL MODEL;

ANIMALS; ANTIBODIES, MONOCLONAL; BIOREACTORS; CENTRIFUGATION; CHO CELLS; CHROMATOGRAPHY, AFFINITY; COMPUTER SIMULATION; COSTS AND COST ANALYSIS; CRICETULUS; FILTRATION; MODELS, THEORETICAL; PRIMARY CELL CULTURE; SOFTWARE;

EID: 84886736376     PISSN: 87567938     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.1776     Document Type: Article

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