Knee loading reduces MMP13 activity in the mouse cartilage

BMC Musculoskeletal Disorders

Volumn 14, Issue , 2013, Pages

  Hamamura, Kazunori ^a   Zhang, Ping ^a,b   Zhao, Liming ^a   Shim, Joon W ^a   Chen, Andy ^a   Dodge, Todd R ^a   Wan, Qiaoqiao ^a   Shih, Han ^a   Na, Sungsoo ^a   Lin, Chien Chi ^a   Sun, Hui Bin ^c   Yokota, Hiroki ^a,d  

^a Indiana University Purdue University Indianapolis   (United States)

^b TIANJIN MEDICAL UNIVERSITY   (China)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^d INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cartilage; Chondrocyte; Knee loading; MMP13; Osteoarthritis; Rac1

Indexed keywords

COLLAGENASE 3; GUANOSINE TRIPHOSPHATASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; RAC1 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DENSITY; BONE MINERAL; CARTILAGE; CARTILAGE CELL; CARTILAGE DEGENERATION; CONTROLLED STUDY; FEMALE; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; KNEE; LOADING TEST; MOLECULAR IMAGING; MOUSE; NONHUMAN; OSTEOARTHRITIS; PROTEIN PHOSPHORYLATION; SHAM PROCEDURE; SHEAR STRESS;

ANIMALS; CARTILAGE, ARTICULAR; CELL LINE; CHONDROCYTES; COLLAGENASES; DOWN-REGULATION; FEMALE; GELATINASES; HUMANS; KNEE JOINT; MATRIX METALLOPROTEINASE 13; MICE; MICE, INBRED C57BL; NF-KAPPA B; OSTEOARTHRITIS, KNEE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RAC1 GTP-BINDING PROTEIN; RNA, SMALL INTERFERING; STRESS, MECHANICAL; WEIGHT-BEARING;

EID: 84886731639     PISSN: None     EISSN: 14712474     Source Type: Journal    
DOI: 10.1186/1471-2474-14-312     Document Type: Article

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