Association of ADAMTS5 gene polymorphisms with osteoarthritis in Chinese Han population: A community-based case-control study

Rheumatology International

Volumn 33, Issue 11, 2013, Pages 2893-2897

  Gu, Jiaao ^a   Rong, Jiesheng ^a   Guan, Fulin ^a   Jiang, Liying ^a   Zhang, Ting ^a   Tao, Shuqing ^a   Guan, Guofa ^a   Xu, Liang ^a   Tao, Tianzun ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

ADAMTS5; Gene polymorphism; Osteoarthritis

Indexed keywords

ADULT; ARTICLE; CERVICAL SPONDYLOSIS; CHINESE; COMMUNITY CARE; EXON; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; HAND OSTEOARTHRITIS; HUMAN; KNEE OSTEOARTHRITIS; LUMBAR OSTEOARTHRITIS; MAJOR CLINICAL STUDY; MALE; OSTEOARTHRITIS; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADAM PROTEINS; ADULT; AGED; ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; CHINA; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HUMANS; MALE; MIDDLE AGED; OSTEOARTHRITIS; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84886721650     PISSN: 01728172     EISSN: 1437160X     Source Type: Journal    
DOI: 10.1007/s00296-012-2506-1     Document Type: Article

References (20)

1. Peyron JG (1979) Epidemiologic and etiologic approach of osteoarthritis. Semin Arthritis Rheum 8:288-306
2. Molloy ES, McCarthy GM (2005) Eicosanoids osteoarthritis, and crystal deposition diseases. Curr Opin Rheumatol 17:346-350
3. Reginato AM, Olsen BR (2002) The role of structural genes in the pathogenesis of osteoarthritic disorders. Arthritis Res 4:337-345
4. Yuan GH, Masuko-Hongo K, Kato T, Nishioka K (2003) Immunologic intervention in the pathogenesis of osteoarthritis. Arthritis Rheum 48:602-611
5. Aigner T, Dudhia J (2003) Genomics of osteoarthritis. Curr Opin Rheumatol 15:634-640
6. Valdes AM, Loughlin J, Timms KM, van Meurs JJ, Southam L, Wilson SG, Doherty S, Lories RJ, Luyten FP, Gutin A, Abkevich V, Ge D, Hofman A, Uitterlinden AG, Hart DJ, Zhang F, Zhai G, Egli RJ, Doherty M, Lanchbury J, Spector TD (2008) Genome-wide association scan identifies a prostaglandin- endoperoxide synthase 2 variant involved in risk of knee osteoarthritis. Am J Hum Genet 82:1231-1240
7. Maxis K, Delalandre A, Martel-Pelletier J, Pelletier JP, Duval N, Lajeunesse D (2006) The shunt from the cyclooxygenase to lipoxygenase pathway in human osteoarthritic subchondral osteoblasts is linked with a variable expression of the 5-lipoxygenase-activating protein. Arthritis Res Ther 8:R181
8. Nagase H, Kashiwagi M (2003) Aggrecanases and cartilage matrix degradation. Arthritis Res Ther 5:94-103
9. Lark MW, Bayne EK, Flanagan J, Harper CF, Hoerrner LA, Hutchinson NI, Singer II, Donatelli SA, Weidner JR, Williams HR, Mumford RA, Lohmander LS (1997) Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints. J Clin Invest 100:93-106
10. Gendron C, Kashiwagi M, Lim NH, Enghild JJ, Thøgersen IB, Hughes C, Caterson B, Nagase H (2007) Proteolytic activities of human ADAMTS-5 comparative studies with ADAMTS-4. J Biol Chem 282:18294-18306
11. Glasson SS, Askew R, Sheppard B, Carito B, Blanchet T, Ma HL, Flannery CR, Peluso D, Kanki K, Yang Z, Majumdar MK, Morris EA (2005) Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis. Nature (London) 434:644-648
12. Song RH, Tortorella MD, Malfait AM, Alston JT, Yang Z, Arner EC, Griggs DW (2007) Aggrecan degradation in human articular cartilage explants is mediated by both ADAMTS-4 and ADAMTS-5. Arthritis Rheum 56:575-585
13. Rodriguez-Lopez J, Mustafa Z, Pombo-Suarez M, Malizos KN, Rego I, Blanco FJ, Tsezou A, Loughlin J, Gomez-Reino JJ, Gonzalez A (2008) Genetic variation including nonsynonymous polymorphisms of a major aggrecanase, ADAMTS-5, in susceptibility to osteoarthritis. Arthritis Rheum 58:435-441
14. Kellgren JH, Lawrence JS (1957) Radiological assessment of osteo-arthrosis. Ann Rheum Dis 16:16494-16502
15. Holland BS, Copenhaver MD (1987) An improved sequentially rejective bonferroni test procedure. Biometrics 43:417-423
16. Felson DT (2004) An update on the pathogenesis and epidemiology of osteoarthritis. Radiol Clin North Am 42:1-9
17. Hollander AP, Pidoux I, Reiner A, Rorabeck C, Bourne R, Poole AR (1995) Damage to type II collagen in aging and osteoarthritis starts at the articular surface, originates around chondrocytes, and extends into the cartilage with progressive degeneration. J Clin Invest 96:2859-2869
18. Verma P, Dalal K (2011) ADAMTS-4 and ADAMTS-5: key enzymes in osteoarthritis. J Cell Biochem 112:3507-3514
19. Bondeson J, Wainwright S, Hughes C, Caterson B (2008) The regulation of the ADAMTS4 and ADAMTS5 aggrecanases in osteoarthritis: a review. Clin Exp Rheumatol 26:139-145
20. Prasadam I, Crawford R, Xiao Y (2012) Aggravation of ADAMTS and matrix metalloproteinase production and role of ERK1/2 pathway in the interaction of osteoarthritic subchondral bone osteoblasts and articular cartilage chondrocytes - possible pathogenic role in osteoarthritis. J Rheumatol 39:621-634