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Volumn 8, Issue 24, 2013, Pages 2249-2255

Degenerative alterations in noradrenergic neurons of the locus coeruleus in Alzheimer's disease

Author keywords

Alzheimer's disease; Grants supported paper; Locus coeruleus; Neural regeneration; Neuroregeneration; Noradrenergic neuron; Presenilin 1; Senile plaques; Tyrosine hydroxylase; amyloid

Indexed keywords

AMYLOID PRECURSOR PROTEIN; PRESENILIN 1; TYROSINE 3 MONOOXYGENASE; AMYLOID BETA PROTEIN;

EID: 84886698711     PISSN: 16735374     EISSN: 18767958     Source Type: Journal    
DOI: 10.3969/j.issn.1673-5374.2013.24.004     Document Type: Article
Times cited : (23)

References (33)
  • 1
    • 59449084228 scopus 로고    scopus 로고
    • Drug enhancement of memory consolidation: Historical perspective and neurobiological implications
    • McGaugh JL, Roozendaal B. Drug enhancement of memory consolidation: historical perspective and neurobiological implications. Psychopharmacology (Berl). 2009; 202(1-3):3-14.
    • (2009) Psychopharmacology (Berl) , vol.202 , Issue.1-3 , pp. 3-14
    • McGaugh, J.L.1    Roozendaal, B.2
  • 2
    • 80054871710 scopus 로고    scopus 로고
    • Proteomic identification of specifically carbonylated brain proteins in APP(NLh)/APP(NLh) × PS-1(P264L)/PS-1(P264L) human double mutant knockin mice model of Alzheimer disease as a function of age
    • Sultana R, Robinson RA, Di Domenico F, et al. Proteomic identification of specifically carbonylated brain proteins in APP(NLh)/APP(NLh) × PS-1(P264L)/PS-1(P264L) human double mutant knockin mice model of Alzheimer disease as a function of age. J Proteomics. 2011;74(11):2430-2440.
    • (2011) J Proteomics , vol.74 , Issue.11 , pp. 2430-2440
    • Sultana, R.1    Robinson, R.A.2    Di Domenico, F.3
  • 3
    • 0030293676 scopus 로고    scopus 로고
    • Familial Alzheimer's diseaselinked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo
    • Borchelt DR, Thinakaran G, Eckman CB, et al. Familial Alzheimer's diseaselinked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo. Neuron. 1996; 17(5):1005-1013.
    • (1996) Neuron , vol.17 , Issue.5 , pp. 1005-1013
    • Borchelt, D.R.1    Thinakaran, G.2    Eckman, C.B.3
  • 4
    • 0034531646 scopus 로고    scopus 로고
    • The value of transgenic models for the study of Neurodegenerative disease
    • Price DL, Wong PC, Markowska AL, et al. The value of transgenic models for the study of Neurodegenerative disease. Ann N Y Acad Sci. 2000;920:179-191.
    • (2000) Ann N Y Acad Sci , vol.920 , pp. 179-191
    • Price, D.L.1    Wong, P.C.2    Markowska, A.L.3
  • 5
    • 84861755926 scopus 로고    scopus 로고
    • Sensorimotor gating and memory deficits in an APP/PS1 double transgenic mouse model of Alzheimer's disease
    • Wang H, He J, Zhang R, et al. Sensorimotor gating and memory deficits in an APP/PS1 double transgenic mouse model of Alzheimer's disease. Behav Brain Res. 2012;233(1):237-243.
    • (2012) Behav Brain Res , vol.233 , Issue.1 , pp. 237-243
    • Wang, H.1    He, J.2    Zhang, R.3
  • 6
    • 84861477007 scopus 로고    scopus 로고
    • Expression of ErbB4 in the neurons of Alzheimer's disease brain and APP/PS1 mice, a model of Alzheimer's disease
    • Woo RS, Lee JH, Yu HN, et al. Expression of ErbB4 in the neurons of Alzheimer's disease brain and APP/PS1 mice, a model of Alzheimer's disease. Anat Cell Biol. 2011;44(2):116-127.
    • (2011) Anat Cell Biol , vol.44 , Issue.2 , pp. 116-127
    • Woo, R.S.1    Lee, J.H.2    Yu, H.N.3
  • 8
    • 84860275678 scopus 로고    scopus 로고
    • Identification and characterization of an aβ oligomer precipitating peptide that may be useful to explore gene therapeutic approaches to Alzheimer disease
    • Funke SA, Liu H, Sehl T, et al. Identification and characterization of an aβ oligomer precipitating peptide that may be useful to explore gene therapeutic approaches to Alzheimer disease. Rejuvenation Res. 2012;15(2):144-157.
    • (2012) Rejuvenation Res , vol.15 , Issue.2 , pp. 144-157
    • Funke, S.A.1    Liu, H.2    Sehl, T.3
  • 9
    • 84863337843 scopus 로고    scopus 로고
    • Alzheimer mechanisms and therapeutic strategies
    • Huang Y, Mucke L. Alzheimer mechanisms and therapeutic strategies. Cell. 2012;148(6):1204-1222.
    • (2012) Cell , vol.148 , Issue.6 , pp. 1204-1222
    • Huang, Y.1    Mucke, L.2
  • 10
    • 84857558439 scopus 로고    scopus 로고
    • Immunotherapy for Alzheimer's disease: From anti-β-amyloid to taubased immunization strategies
    • Panza F, Frisardi V, Solfrizzi V, et al. Immunotherapy for Alzheimer's disease: from anti-β-amyloid to taubased immunization strategies. Immunotherapy. 2012;4(2): 213-238.
    • (2012) Immunotherapy , vol.4 , Issue.2 , pp. 213-238
    • Panza, F.1    Frisardi, V.2    Solfrizzi, V.3
  • 11
    • 0021077736 scopus 로고
    • The locus coeruleus and its possible role in ageing and degenerative disease of the human central nervous system
    • Mann D. The locus coeruleus and its possible role in ageing and degenerative disease of the human central nervous system. Mech Ageing Dev. 1983;23(1):73-94.
    • (1983) Mech Ageing Dev , vol.23 , Issue.1 , pp. 73-94
    • Mann, D.1
  • 12
    • 0026492005 scopus 로고
    • Disease specific patterns of locus coeruleus cell loss
    • German DC, Manaye KF, White III CL, et al. Disease specific patterns of locus coeruleus cell loss. Ann Neurol. 1992;(32):667-676.
    • (1992) Ann Neurol , Issue.32 , pp. 667-676
    • German, D.C.1    Manaye, K.F.2    White III, C.L.3
  • 13
    • 0035993240 scopus 로고    scopus 로고
    • Noradrenergic regulation of inflammatory gene expression in brain
    • Feinstein DL, Heneka MT, Gavrilyuk V, et al. Noradrenergic regulation of inflammatory gene expression in brain. Neurochem Int. 2002;41(5):357-365.
    • (2002) Neurochem Int , vol.41 , Issue.5 , pp. 357-365
    • Feinstein, D.L.1    Heneka, M.T.2    Gavrilyuk, V.3
  • 14
    • 32544449785 scopus 로고    scopus 로고
    • Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice
    • Heneka MT, Ramanathan M, Jacobs AH, et al. Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice. J Neurosci. 2006;26(5):1343-1354.
    • (2006) J Neurosci , vol.26 , Issue.5 , pp. 1343-1354
    • Heneka, M.T.1    Ramanathan, M.2    Jacobs, A.H.3
  • 15
    • 26944438305 scopus 로고    scopus 로고
    • Network reset: A simplified overarching theory of locus coeruleus noradrenaline function
    • Bouret S, Sara SJ. Network reset: a simplified overarching theory of locus coeruleus noradrenaline function. Trends Neurosci. 2005;28(11):574-582.
    • (2005) Trends Neurosci , vol.28 , Issue.11 , pp. 574-582
    • Bouret, S.1    Sara, S.J.2
  • 16
    • 27644444245 scopus 로고    scopus 로고
    • The PDAPP mouse model of Alzheimer's disease: Locus coeruleus neuronal shrinkage
    • German DC, Nelson O, Liang F, et al. The PDAPP mouse model of Alzheimer's disease: locus coeruleus neuronal shrinkage. J Comp Neurol. 2005;492(4):469-476.
    • (2005) J Comp Neurol , vol.492 , Issue.4 , pp. 469-476
    • German, D.C.1    Nelson, O.2    Liang, F.3
  • 17
    • 0030820317 scopus 로고    scopus 로고
    • Spatial, temporal and numeric analysis of Alzheimer changes in the nucleus coeruleus
    • Busch C, Bohl J, Ohm TG, et al. Spatial, temporal and numeric analysis of Alzheimer changes in the nucleus coeruleus. Neurobiol Aging. 1997;18(4):401-406.
    • (1997) Neurobiol Aging , vol.18 , Issue.4 , pp. 401-406
    • Busch, C.1    Bohl, J.2    Ohm, T.G.3
  • 18
    • 0037151046 scopus 로고    scopus 로고
    • Accelerated plaque accumulation, associative learning deficits, and upregulation of alpha 7 nicotinic receptor protein in transgenic mice coexpressing mutant human presenilin 1 and amyloid precursor proteins
    • Dineley KT, Xia X, Bui D, et al& Accelerated plaque accumulation, associative learning deficits, and upregulation of alpha 7 nicotinic receptor protein in transgenic mice coexpressing mutant human presenilin 1 and amyloid precursor proteins. J Biol Chem. 2002; 277(25):22768-22780.
    • (2002) J Biol Chem , vol.277 , Issue.25 , pp. 22768-22780
    • Dineley, K.T.1    Xia, X.2    Bui, D.3
  • 19
    • 84861805073 scopus 로고    scopus 로고
    • Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer's disease
    • Dhawan G, Combs CK. Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer's disease. J Neuroinflammation. 2012; 9:117.
    • (2012) J Neuroinflammation , vol.9 , pp. 117
    • Dhawan, G.1    Combs, C.K.2
  • 20
    • 84861844315 scopus 로고    scopus 로고
    • Critical role of soluble amyloid-β for early hippocampal hyperactivity in a mouse model of Alzheimer's disease
    • Busche MA, Chen X, Henning HA, et al. Critical role of soluble amyloid-β for early hippocampal hyperactivity in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A. 2012;109(22):8740-8745.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , Issue.22 , pp. 8740-8745
    • Busche, M.A.1    Chen, X.2    Henning, H.A.3
  • 21
    • 84861142911 scopus 로고    scopus 로고
    • Alzheimer's disease amyloid β-protein mutations and deletions that define neuronal binding/internalization as early stage nonfibrillar/fibrillar aggregates and late stage fibrils
    • Poduslo JF, Howell KG, Olson NC, et al. Alzheimer's disease amyloid β-protein mutations and deletions that define neuronal binding/internalization as early stage nonfibrillar/fibrillar aggregates and late stage fibrils. Biochemistry. 2012;51(19):3993-4003.
    • (2012) Biochemistry , vol.51 , Issue.19 , pp. 3993-4003
    • Poduslo, J.F.1    Howell, K.G.2    Olson, N.C.3
  • 22
    • 33644516288 scopus 로고    scopus 로고
    • Contribution of inflammatory processes to Alzheimer's disease: Molecular mechanisms
    • Sastre M, Klockgether T, Heneka MT. Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms. Int J Dev Neurosci. 2006;24(2-3):167-176.
    • (2006) Int J Dev Neurosci , vol.24 , Issue.2-3 , pp. 167-176
    • Sastre, M.1    Klockgether, T.2    Heneka, M.T.3
  • 23
    • 79851509868 scopus 로고    scopus 로고
    • Distinct adrenergic system changes and neuroinflammation in response to induced locus ceruleus degeneration in APP/PS1 transgenic mice
    • Jardanhazi-Kurutz D, Kummer MP, Terwel D, et al. Distinct adrenergic system changes and neuroinflammation in response to induced locus ceruleus degeneration in APP/PS1 transgenic mice. Neuroscience. 2011;176:396-407.
    • (2011) Neuroscience , vol.176 , pp. 396-407
    • Jardanhazi-Kurutz, D.1    Kummer, M.P.2    Terwel, D.3
  • 24
    • 0036546148 scopus 로고    scopus 로고
    • Noradrenergic depletion potentiates beta-amyloid-induced cortical inflammation: Implications for Alzheimer's disease
    • Heneka MT, Galea E, Gavriluyk V, et al. Noradrenergic depletion potentiates betaamyloid-induced cortical inflammation: implications for Alzheimer's disease. J Neurosci. 2002;22(7):2434-2442.
    • (2002) J Neurosci , vol.22 , Issue.7 , pp. 2434-2442
    • Heneka, M.T.1    Galea, E.2    Gavriluyk, V.3
  • 25
    • 77956225289 scopus 로고    scopus 로고
    • Induced LC degeneration in APP/PS1 transgenic mice accelerates early cerebral amyloidosis and cognitive deficits
    • Jardanhazi-Kurutz D, Kummer MP, Terwel D, et al. Induced LC degeneration in APP/PS1 transgenic mice accelerates early cerebral amyloidosis and cognitive deficits. Neurochem Int. 2010;57(4):375-382.
    • (2010) Neurochem Int , vol.57 , Issue.4 , pp. 375-382
    • Jardanhazi-Kurutz, D.1    Kummer, M.P.2    Terwel, D.3
  • 26
    • 41749124775 scopus 로고    scopus 로고
    • Microglia-neuron interaction in inflammatory and degenerative diseases: Role of cholinergic and noradrenergic systems
    • Carnevale D, De Simone R, Minghetti L. Microglia-neuron interaction in inflammatory and degenerative diseases: role of cholinergic and noradrenergic systems. CNS Neurol Disord Drug Targets. 2007;6(6):388-397.
    • (2007) CNS Neurol Disord Drug Targets , vol.6 , Issue.6 , pp. 388-397
    • Carnevale, D.1    de Simone, R.2    Minghetti, L.3
  • 27
    • 65249147834 scopus 로고    scopus 로고
    • Relevance of transgenic mouse models to human Alzheimer disease
    • Morrissette DA, Parachikova A, Green KN, et al. Relevance of transgenic mouse models to human Alzheimer disease. J Biol Chem. 2009;284(10):6033-6037.
    • (2009) J Biol Chem , vol.284 , Issue.10 , pp. 6033-6037
    • Morrissette, D.A.1    Parachikova, A.2    Green, K.N.3
  • 28
    • 80051750907 scopus 로고    scopus 로고
    • Hippocampal synaptic plasticity in Alzheimer's disease: What have we learned so far from transgenic models
    • Marchetti C, Marie H. Hippocampal synaptic plasticity in Alzheimer's disease: what have we learned so far from transgenic models. Rev Neurosci. 2011;22(4):373-402.
    • (2011) Rev Neurosci , vol.22 , Issue.4 , pp. 373-402
    • Marchetti, C.1    Marie, H.2
  • 29
    • 85173358131 scopus 로고    scopus 로고
    • The Ministry of Science and Technology of the People's Republic of China. Guidance Suggestions for the Care and Use of Laboratory Animals. 2006-09-30
    • The Ministry of Science and Technology of the People's Republic of China. Guidance Suggestions for the Care and Use of Laboratory Animals. 2006-09-30.
  • 30
    • 34548287931 scopus 로고    scopus 로고
    • Catecholaminergic neuronal loss in locus coeruleus of aged female dtg APP/PS1 mice
    • O'Neil JN, Mouton PR, Tizabi Y, et al. Catecholaminergic neuronal loss in locus coeruleus of aged female dtg APP/PS1 mice. J Chem Neuroanat. 2007;34(3-4):102-107.
    • (2007) J Chem Neuroanat , vol.34 , Issue.3-4 , pp. 102-107
    • O'Neil, J.N.1    Mouton, P.R.2    Tizabi, Y.3
  • 31
    • 0032424914 scopus 로고    scopus 로고
    • Stereological analysis of astrocyte and microglia in aging mouse hippocampus
    • Long JM, Kalehua AN, Muth NJ, et al. Stereological analysis of astrocyte and microglia in aging mouse hippocampus. Neurobiol Aging. 1998;19(5):497-503.
    • (1998) Neurobiol Aging , vol.19 , Issue.5 , pp. 497-503
    • Long, J.M.1    Kalehua, A.N.2    Muth, N.J.3
  • 32
    • 79960800565 scopus 로고    scopus 로고
    • Effect of neocortical and hippocampal amyloid deposition upon galaninergic and cholinergic neurites in AβPPswe/PS1ΔE9 mice
    • Kelley CM, Perez SE, Overk CR, et al. Effect of neocortical and hippocampal amyloid deposition upon galaninergic and cholinergic neurites in AβPPswe/PS1ΔE9 mice. J Alzheimers Dis. 2011;25(3):491-504.
    • (2011) J Alzheimers Dis , vol.25 , Issue.3 , pp. 491-504
    • Kelley, C.M.1    Perez, S.E.2    Overk, C.R.3
  • 33
    • 79951672948 scopus 로고    scopus 로고
    • Stereological estimation of the total number of myelinated callosal fibers in human subjects
    • Riise J, Pakkenberg B. Stereological estimation of the total number of myelinated callosal fibers in human subjects. J Anat. 2011;218(3):277-284.
    • (2011) J Anat , vol.218 , Issue.3 , pp. 277-284
    • Riise, J.1    Pakkenberg, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.