PDIP38 is translocated to the spliceosomes/nuclear speckles in response to UV-induced DNA damage and is required for UV-induced alternative splicing of MDM2

Cell Cycle

Volumn 12, Issue 19, 2013, Pages 3373-3382

  Wong, Agnes ^a   Zhang, Sufang ^a   Mordue, Dana ^a   Wu, Joseph M ^a   Zhang, Zhongtao ^a   Darzynkiewicz, Zbigniew ^a   Lee, Ernest Y C ^a   Lee, Marietta Y W T ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

Alternative splicing; DNA damage; DNA polymerase ; MDM2; Nuclear speckles; PDIP38; Poldip2; Spliceosomes

Indexed keywords

ALPHA AMANITIN; DNA BINDING PROTEIN; POLYMERASE DELTA INTERACTING PROTEIN 38; PROTEIN MDM2; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; DNA DAMAGE; FEMALE; GENE TARGETING; GENE TRANSLOCATION; GENETIC TRANSCRIPTION; HELA CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLICEOSOME; ULTRAVIOLET RADIATION;

ALTERNATIVE SPLICING; DNA DAMAGE; DNA POLYMERASE Δ; MDM2; NUCLEAR SPECKLES; PDIP38; POLDIP2; SPLICEOSOMES;

ALTERNATIVE SPLICING; CELL LINE, TUMOR; CELL NUCLEUS; DACTINOMYCIN; DNA DAMAGE; HELA CELLS; HUMANS; NUCLEAR PROTEINS; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTO-ONCOGENE PROTEINS C-MDM2; RNA INTERFERENCE; RNA, SMALL INTERFERING; SPLICEOSOMES; ULTRAVIOLET RAYS;

EID: 84886694887     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.26221     Document Type: Article

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