PDIP38 associates with proteins constituting the mitochondrial DNA nucleoid

Journal of Biochemistry

Volumn 138, Issue 6, 2005, Pages 673-678

  Cheng, Xiaoli ^a,b   Kanki, Tomotake ^a   Fukuoh, Atsushi ^a   Ohgaki, Kippei ^a   Takeya, Ryu ^c   Aoki, Yoshimasa ^a   Hamasaki, Naotaka ^a   Kang, Dongchon ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b ZHENGZHOU UNIVERSITY   (China)

^c KYUSHU UNIVERSITY   (Japan)

Author keywords

Mitochondria; Mitochondrial DNA; Mitochondrial transcription factor A (TFAM); Nucleoid; Proteomics

Indexed keywords

BINDING PROTEIN; DNA DIRECTED DNA POLYMERASE DELTA; ENDOPEPTIDASE LA; FORMALDEHYDE; HEAT SHOCK PROTEIN; MITOCHONDRIAL DNA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; PROTEIN PDIP38; RECOMBINANT PROTEIN; SINGLE STRANDED DNA; TRANSCRIPTION FACTOR; TRITON X 100; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CELL FRACTIONATION; CONTROLLED STUDY; CROSS LINKING; HELA CELL; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MITOCHONDRION; PROTEOMICS;

EID: 32944481373     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/jb/mvi169     Document Type: Article

References (18)

1. Falkenberg, M., Gaspari, M., Rantanen, A., Trifunovic, A., Larsson, N.G., and Gustafsson, C.M. (2002) Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA. Nat. Genet. 31, 289-294
2. Ohno, T., Umeda, S., Hamasaki, N., and Kang, D. (2000) Binding of human mitochondrial transcription factor A, an HMG box protein, to a four-way DNA junction. Biochem. Biophys. Res. Commun. 271, 492-498
3. Miyakawa, I., Sando, N., Kawano, S., Nakamura, S., and Kuroiwa, T. (1987) Isolation of morphologically intact mitochondrial nucleoids from the yeast, Saccharomyces cerevisiae. J. Cell Sci. 88, 431-439
4. Kaufman, B.A., Kolesar, J.E., Perlman, P.S., and Butow, R.A. (2003) A function for the mitochondrial chaperonin Hsp60 in the structure and transmission of mitochondrial DNA nucleoids in Saccharomyces cerevisiae. J. Cell Biol. 163, 457-461
5. Bogenhagen, D.F., Wang, Y., Shen, E.L., and Kobayashi, R. (2003) Protein components of mitochondrial DNA nucleoids in higher eukaryotes. Mol. Cell. Proteomics 2, 1205-1216
6. Zelenaya-Troitskaya, O., Newman, S.M., Okamoto, K., Perlman, P.S., and Butow, R.A. (1998) Functions of the high mobility group protein, Abf2p, in mitochondrial DNA segregation, recombination and copy number in Saccharomyces cerevisiae. Genetics 148, 1763-1776
7. Alam, T.I., Kanki, T., Muta, T., Ukaji, K., Abe, Y., Nakayama, H., Takio, K., Hamasaki, N., and Kang, D. (2003) Human mitochondrial DNA is packaged with TFAM. Nucleic Acids Res 31, 1640-1645
8. Kanki, T., Nakayama, H., Sasaki, N., Takio, K., Alam, T.I., Hamasaki, N., and Kang, D. (2004) Mitochondrial nucleoid and transcription factor A. Ann. N.Y. Acad. Sci. 1011, 61-68
9. Spelbrink, J.N., Li, F.Y., Tiranti, V., Nikali, K., Yuan, Q.P., Tariq, M., Wanrooij, S., Garrido, N., Comi, G., Morandi, L., Santoro, L., Toscane, A., Fabrizi, G.M., Somer, H., Croxen, R., Beeson, D., Poulton, J., Suomalainen, A., Jacobs, H.T., Zeviani, M., and Larsson, C. (2001) Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene 4-like protein localized in mitochondria. Nat. Genet. 28, 223-231
10. Takamatsu, C., Umeda, S., Ohsato, T., Ohno, T., Abe, Y., Fukuoh, A., Shinagawa, H., Hamasaki, N., and Kang, D. (2002) Regulation of mitochondrial D-loops by transcription factor A and single-stranded DNA-binding protein. EMBO Rep. 3, 451-456
11. Kanki, T., Ohgaki, K., Gaspari, M., Gustafsson, C.M., Fukuoh, A., Sasaki, N., Hamasaki, N., and Kang, D. (2004) Architectural role of TFAM in maintenance of human mitochondrial DNA. Mol. Cell. Biol. 24, 9823-9834
12. Parisi, M.A., Xu, B., and Clayton, D.A. (1993) A human mitochondrial transcriptional activator can functionally replace a yeast mitochondrial HMG-box protein both in vivo and in vitro. Mol. Cell. Biol. 13, 1951-1961
13. Liu, L., Rodriguez-Belmonte, E.M., Mazloum, N., Xie, B., and Lee, M.Y. (2003) Identification of a novel protein, PDIP38, that interacts with the p50 subunit of DNA polymerase delta and proliferating cell nuclear antigen. J. Biol. Chem. 278, 10041-10047
14. Miyako, K., Irie, T., Muta, T., Umeda, S., Kai, Y., Fujiwara, T., Takeshige, K., and Kang, D. (1999) 1-Methyl-4-phenylpyridinium ion (MPP+) selectively inhibits the replication of mitochondrial DNA. Eur. J. Biochem. 259, 412-118
15. Ohsato, T., Ishihara, N., Muta, T., Umeda, S., Dceda, S., Mihara, K., Hamasaki, N., and Kang, D. (2002) Mammalian mitochondrial endonuclease G: digestion of R-loops and localization m intermembrane space. Eur. J. Biochem. 269, 5675-5770
16. Claros, M.G. and Vincens, P. (1996) Computational method to predict mitochondrially imported proteins and their targeting sequences. Eur. J. Biochem. 241, 779-786
17. Xie, B., Li, H., Wang, Q., Xie, S., Rahmeh, A., Dai, W., and Lee, M.Y. (2005) Further characterization of human DNA polymerase delta interacting protein 38. J. Biol. Chem. 280, 22375-22384
18. Liu, T., Lu, B., Lee, I., Ondrovicova, G., Kutejova, E., and Suzuki, C.K. (2004) DNA and RNA binding by the mitochondrial Ion protease is regulated by nucleotide and protein substrate. J. Biol. Chem. 279, 13902-13910