Quantitation of pyridyloxobutyl-DNA adducts in tissues of rats treated chronically with (R)- or (S)-N′-nitrosonornicotine (NNN) in a carcinogenicity study

Chemical Research in Toxicology

Volumn 26, Issue 10, 2013, Pages 1526-1535

  Zhao, Lijiao ^a   Balbo, Silvia ^b   Wang, Mingyao ^b   Upadhyaya, Pramod ^b   Khariwala, Samir S ^b   Villalta, Peter W ^b   Hecht, Stephen S ^b  

^a BEIJING UNIVERSITY OF TECHNOLOGY   (China)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; DNA; NITROSONORNICOTINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CHEMICAL CARCINOGENESIS; CHEMICAL STRUCTURE; CHRONIC TOXICITY; CONTROLLED STUDY; DNA ADDUCT; DNA REPAIR; ELECTROSPRAY MASS SPECTROMETRY; ESOPHAGUS CANCER; ESOPHAGUS MUCOSA; HYDROXYLATION; LIQUID CHROMATOGRAPHY; LIVER; LONG TERM EXPOSURE; LUNG; MOUTH CANCER; MOUTH MUCOSA; NONHUMAN; NOSE MUCOSA; OLFACTORY EPITHELIUM; QUANTITATIVE ANALYSIS; RAT; TANDEM MASS SPECTROMETRY; TOBACCO;

NICOTIANA TABACUM; RATTUS;

ANIMALS; CARCINOGENS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGUANOSINE; DNA ADDUCTS; DRINKING WATER; INTESTINAL MUCOSA; LIVER; LUNG; MALE; MOUTH MUCOSA; NITROSAMINES; PYRIDINES; RATS; RATS, INBRED F344; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STEREOISOMERISM; THYMIDINE; TIME FACTORS;

EID: 84886694758     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx400235x     Document Type: Article

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