Quantitation of pyridylhydroxybutyl-DNA adducts in liver and lung of F-344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol

Chemical Research in Toxicology

Volumn 21, Issue 7, 2008, Pages 1468-1476

  Upadhyaya, Pramod ^a   Kalscheuer, Stephen ^a   Hochalter, J Bradley ^a   Villalta, Peter W ^a   Hecht, Stephen S ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANOL; 4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; CYTOCHROME P450; DRINKING WATER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CATALYST; DNA ADDUCT; ELECTROSPRAY MASS SPECTROMETRY; ENANTIOMER; HYDROXYLATION; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; LIVER; LUNG PARENCHYMA; NONHUMAN; RAT;

ANIMALS; CARCINOGENS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA; DNA ADDUCTS; LIVER; LUNG; MAGNETIC RESONANCE SPECTROSCOPY; MALE; NITROSAMINES; PYRIDINES; RATS; RATS, INBRED F344; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STEREOISOMERISM; TANDEM MASS SPECTROMETRY;

NICOTIANA TABACUM; RATTUS;

EID: 49049095293     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx8001109     Document Type: Article

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