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Volumn 12, Issue 19, 2013, Pages 3335-3342

Changing T-cell enigma: Cancer killing or cancer control?

Author keywords

Cancer therapy; Cell cycle control; Growth arrest; Immune therapy; Interferon ?; P16Ink4a; Senescence; Thelper 1 cells; Tumor dormancy; Tumor necrosis factor

Indexed keywords

CHEMOKINE; CYTOKINE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; PROGRAMMED DEATH 1 LIGAND 1; PROTEIN P53; TRANSFORMING GROWTH FACTOR BETA; TRASTUZUMAB EMTANSINE; TUMOR ANTIGEN; TUMOR NECROSIS FACTOR;

EID: 84886678117     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.26060     Document Type: Review
Times cited : (13)

References (59)
  • 2
    • 77953225810 scopus 로고    scopus 로고
    • Tumor cells disseminate early, but immunosurveillance limits metastatic outgrowth, in a mouse model of melanoma
    • PMID:20501944
    • Eyles J, Puaux AL, Wang X, Toh B, Prakash C, Hong M, Tan TG, Zheng L, Ong LC, Jin Y, et al. Tumor cells disseminate early, but immunosurveillance limits metastatic outgrowth, in a mouse model of melanoma. J Clin Invest 2010; 120:2030- 9; PMID:20501944; http://dx.doi.org/10.1172/JCI42002
    • (2010) J Clin Invest , vol.120 , pp. 2030-2039
    • Eyles, J.1    Puaux, A.L.2    Wang, X.3    Toh, B.4    Prakash, C.5    Hong, M.6    Tan, T.G.7    Zheng, L.8    Ong, L.C.9    Jin, Y.10
  • 3
    • 77953221417 scopus 로고    scopus 로고
    • Early tumor dissemination, but late metastasis: Insights into tumor dormancy
    • PMID:20501952
    • Röcken M. Early tumor dissemination, but late metastasis: insights into tumor dormancy. J Clin Invest 2010; 120:1800-3; PMID:20501952; http://dx.doi.org/10.1172/JCI43424
    • (2010) J Clin Invest , vol.120 , pp. 1800-1803
    • Röcken, M.1
  • 5
    • 0001777467 scopus 로고
    • I. The results of radical operations for the cure of carcinoma of the breast
    • PMID:17861990
    • Halsted WS. I. The Results of Radical Operations for the Cure of Carcinoma of the Breast. Ann Surg 1907; 46:1-19; PMID:17861990; http://dx.doi.org/10.1097/00000658-190707000-00001
    • (1907) Ann Surg , vol.46 , pp. 1-19
    • Halsted, W.S.1
  • 6
    • 0344858950 scopus 로고
    • An incision and method of wound closure for radical mastectomy
    • PMID:14819996
    • Orr TG Jr. An incision and method of wound closure for radical mastectomy. Ann Surg 1951; 133:565-6; PMID:14819996
    • (1951) Ann Surg , vol.133 , pp. 565-566
    • Orr Jr., T.G.1
  • 7
    • 0025866358 scopus 로고
    • Cancer of the breast: A study of 1520 consecutive patients operated on between 1960 and 1980
    • PMID:1888359
    • Péloquin A, Poljicak M, Falardeau M, Gravel D, Moïsescu R, Péloquin L. Cancer of the breast: a study of 1520 consecutive patients operated on between 1960 and 1980. Can J Surg 1991; 34:151-6; PMID:1888359
    • (1991) Can J Surg , vol.34 , pp. 151-156
    • Péloquin, A.1    Poljicak, M.2    Falardeau, M.3    Gravel, D.4    Moïsescu, R.5    Péloquin, L.6
  • 8
    • 0029870954 scopus 로고    scopus 로고
    • The war on cancer
    • DOI 10.1016/S0140-6736(96)91015-6
    • Sporn MB. The war on cancer. Lancet 1996; 347:1377-81; PMID:8637346; http://dx.doi.org/10.1016/S0140-6736(96)91015-6 (Pubitemid 26147937)
    • (1996) Lancet , vol.347 , Issue.9012 , pp. 1377-1381
    • Sporn, M.B.1
  • 9
    • 66449133323 scopus 로고    scopus 로고
    • A change of strategy in the war on cancer
    • PMID:19478766
    • Gatenby RA. A change of strategy in the war on cancer. Nature 2009; 459:508-9; PMID:19478766; http://dx.doi.org/10.1038/459508a
    • (2009) Nature , vol.459 , pp. 508-509
    • Gatenby, R.A.1
  • 10
    • 0029935682 scopus 로고    scopus 로고
    • Involvement of the CD95 (APO-1/Fas) receptor/ligand system in drug-induced apoptosis in leukemia cells
    • DOI 10.1038/nm0596-574
    • Friesen C, Herr I, Krammer PH, Debatin KM. Involvement of the CD95 (APO-1/FAS) receptor/ligand system in drug-induced apoptosis in leukemia cells. Nat Med 1996; 2:574-7; PMID:8616718; http://dx.doi.org/10.1038/nm0596-574 (Pubitemid 26150685)
    • (1996) Nature Medicine , vol.2 , Issue.5 , pp. 574-577
    • Friesen, C.1    Herr, I.2    Krammer, P.H.3    Debatin, K.-M.4
  • 11
    • 16244393359 scopus 로고    scopus 로고
    • Arsenic trioxide triggers a regulated form of caspase-independent necrotic cell death via the mitochondrial death pathway
    • DOI 10.1038/sj.onc.1208233
    • Scholz C, Wieder T, Stärck L, Essmann F, Schulze- Osthoff K, Dörken B, Daniel PT. Arsenic trioxide triggers a regulated form of caspase-independent necrotic cell death via the mitochondrial death pathway. Oncogene 2005; 24:1904-13; PMID:15674346; http://dx.doi.org/10.1038/sj.onc. 1208233 (Pubitemid 40462792)
    • (2005) Oncogene , vol.24 , Issue.11 , pp. 1904-1913
    • Scholz, C.1    Wieder, T.2    Starck, L.3    Essmann, F.4    Schulze-Osthoff, K.5    Dorken, B.6    Daniel, P.T.7
  • 12
    • 84858726313 scopus 로고    scopus 로고
    • Regulation of cell death and autophagy by IKK and NF-kB: Critical mechanisms in immune function and cancer
    • PMID:22435564
    • Baldwin AS. Regulation of cell death and autophagy by IKK and NF-kB: critical mechanisms in immune function and cancer. Immunol Rev 2012; 246:327-45; PMID:22435564; http://dx.doi.org/10.1111/j.1600-065X.2012.01095.x
    • (2012) Immunol Rev , vol.246 , pp. 327-345
    • Baldwin, A.S.1
  • 16
    • 0037143806 scopus 로고    scopus 로고
    • Extremely potent, rapid and costimulation-independent cytotoxic T-cell response against lymphoma cells catalyzed by a single-chain bispecific antibody
    • DOI 10.1002/ijc.10557
    • Dreier T, Lorenczewski G, Brandl C, Hoffmann P, Syring U, Hanakam F, Kufer P, Riethmuller G, Bargou R, Baeuerle PA. Extremely potent, rapid and costimulation-independent cytotoxic T-cell response against lymphoma cells catalyzed by a single-chain bispecific antibody. Int J Cancer 2002; 100:690- 7; PMID:12209608; http://dx.doi.org/10.1002/ijc.10557 (Pubitemid 34832980)
    • (2002) International Journal of Cancer , vol.100 , Issue.6 , pp. 690-697
    • Dreier, T.1    Lorenczewski, G.2    Brandl, C.3    Hoffmann, P.4    Syring, U.5    Hanakam, F.6    Kufer, P.7    Riethmuller, G.8    Bargou, R.9    Baeuerle, P.A.10
  • 18
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • PMID:21376230
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144:646-74; PMID:21376230; http://dx.doi.org/10.1016/j.cell.2011.02.013
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 23
    • 65149083820 scopus 로고    scopus 로고
    • EpCAM, a human tumor-associated antigen promotes Th2 development and tumor immune evasion
    • PMID:19188665
    • Ziegler A, Heidenreich R, Braumüller H, Wolburg H, Weidemann S, Mocikat R, Röcken M. EpCAM, a human tumor-associated antigen promotes Th2 development and tumor immune evasion. Blood 2009; 113:3494-502; PMID:19188665; http://dx.doi.org/10.1182/blood-2008-08-175109
    • (2009) Blood , vol.113 , pp. 3494-3502
    • Ziegler, A.1    Heidenreich, R.2    Braumüller, H.3    Wolburg, H.4    Weidemann, S.5    Mocikat, R.6    Röcken, M.7
  • 24
    • 0034653709 scopus 로고    scopus 로고
    • Eradication of disseminated lymphomas with CpG-DNA activated T helper type 1 cells from nontransgenic mice
    • Egeter O, Mocikat R, Ghoreschi K, Dieckmann A, Röcken M. Eradication of disseminated lymphomas with CpG-DNA activated T helper type 1 cells from nontransgenic mice. Cancer Res 2000; 60:1515-20; PMID:10749115 (Pubitemid 30183417)
    • (2000) Cancer Research , vol.60 , Issue.6 , pp. 1515-1520
    • Egeter, O.1    Mocikat, R.2    Ghoreschi, K.3    Dieckmann, A.4    Rocken, M.5
  • 25
    • 77949530108 scopus 로고    scopus 로고
    • Naive tumor-specific CD4(+) T cells differentiated in vivo eradicate established melanoma
    • PMID:20156973
    • Xie Y, Akpinarli A, Maris C, Hipkiss EL, Lane M, Kwon EK, Muranski P, Restifo NP, Antony PA. Naive tumor-specific CD4(+) T cells differentiated in vivo eradicate established melanoma. J Exp Med 2010; 207:651-67; PMID:20156973; http://dx.doi.org/10.1084/jem.20091921
    • (2010) J Exp Med , vol.207 , pp. 651-667
    • Xie, Y.1    Akpinarli, A.2    Maris, C.3    Hipkiss, E.L.4    Lane, M.5    Kwon, E.K.6    Muranski, P.7    Restifo, N.P.8    Antony, P.A.9
  • 26
    • 77949522803 scopus 로고    scopus 로고
    • Tumor-reactive CD4(+) T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts
    • PMID:20156971
    • Quezada SA, Simpson TR, Peggs KS, Merghoub T, Vider J, Fan X, Blasberg R, Yagita H, Muranski P, Antony PA, et al. Tumor-reactive CD4(+) T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts. J Exp Med 2010; 207:637-50; PMID:20156971; http://dx.doi.org/10.1084/jem.20091918
    • (2010) J Exp Med , vol.207 , pp. 637-650
    • Quezada, S.A.1    Simpson, T.R.2    Peggs, K.S.3    Merghoub, T.4    Vider, J.5    Fan, X.6    Blasberg, R.7    Yagita, H.8    Muranski, P.9    Antony, P.A.10
  • 30
    • 36849028692 scopus 로고    scopus 로고
    • AIF-mediated programmed necrosis: A highly regulated way to die
    • Boujrad H, Gubkina O, Robert N, Krantic S, Susin SA. AIF-mediated programmed necrosis: a highly regulated way to die. Cell Cycle 2007; 6:2612- 9; PMID:17912035; http://dx.doi.org/10.4161/cc.6.21.4842 (Pubitemid 350224042)
    • (2007) Cell Cycle , vol.6 , Issue.21 , pp. 2612-2619
    • Boujrad, H.1    Gubkina, O.2    Robert, N.3    Krantic, S.4    Susin, S.A.5
  • 31
    • 0035283079 scopus 로고    scopus 로고
    • Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3
    • DOI 10.1182/blood.V97.5.1378
    • Wieder T, Essmann F, Prokop A, Schmelz K, Schulze-Osthoff K, Beyaert R, Dörken B, Daniel PT. Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor- ligand interaction and occurs downstream of caspase- 3. Blood 2001; 97:1378-87; PMID:11222383; http://dx.doi.org/10.1182/blood.V97.5.1378 (Pubitemid 32183762)
    • (2001) Blood , vol.97 , Issue.5 , pp. 1378-1387
    • Wieder, T.1    Essmann, F.2    Prokop, A.3    Schmelz, K.4    Schulze-Osthoff, K.5    Beyaert, R.6    Dorken, B.7    Daniel, P.T.8
  • 32
    • 84876906830 scopus 로고    scopus 로고
    • TNF dually mediates resistance and susceptibility to mycobacteria via mitochondrial reactive oxygen species
    • PMID:23582643
    • Roca FJ, Ramakrishnan L. TNF dually mediates resistance and susceptibility to mycobacteria via mitochondrial reactive oxygen species. Cell 2013; 153:521-34; PMID:23582643; http://dx.doi.org/10.1016/j.cell.2013.03.022
    • (2013) Cell , vol.153 , pp. 521-534
    • Roca, F.J.1    Ramakrishnan, L.2
  • 34
    • 79953151458 scopus 로고    scopus 로고
    • Cancer immunoediting: Integrating immunity's roles in cancer suppression and promotion
    • PMID:21436444
    • Schreiber RD, Old LJ, Smyth MJ. Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. Science 2011; 331:1565- 70; PMID:21436444; http://dx.doi.org/10.1126/science.1203486
    • (2011) Science , vol.331 , pp. 1565-1570
    • Schreiber, R.D.1    Old, L.J.2    Smyth, M.J.3
  • 36
    • 45549092607 scopus 로고    scopus 로고
    • Cancer immunology
    • PMID:18565863
    • Finn OJ. Cancer immunology. N Engl J Med 2008; 358:2704-15; PMID:18565863; http://dx.doi.org/10.1056/NEJMra072739
    • (2008) N Engl J Med , vol.358 , pp. 2704-2715
    • Finn, O.J.1
  • 37
    • 0015380016 scopus 로고
    • Tumor dormancy in vivo by prevention of neovascularization
    • PMID:5043412
    • Gimbrone MA Jr., Leapman SB, Cotran RS, Folkman J. Tumor dormancy in vivo by prevention of neovascularization. J Exp Med 1972; 136:261- 76; PMID:5043412; http://dx.doi.org/10.1084/jem.136.2.261
    • (1972) J Exp Med , vol.136 , pp. 261-276
    • Gimbrone Jr., M.A.1    Leapman, S.B.2    Cotran, R.S.3    Folkman, J.4
  • 38
    • 0015804548 scopus 로고
    • Self-regulation of growth in three dimensions
    • PMID:4744009
    • Folkman J, Hochberg M. Self-regulation of growth in three dimensions. J Exp Med 1973; 138:745- 53; PMID:4744009; http://dx.doi.org/10.1084/jem.138.4.745
    • (1973) J Exp Med , vol.138 , pp. 745-753
    • Folkman, J.1    Hochberg, M.2
  • 39
    • 36849010167 scopus 로고    scopus 로고
    • Adaptive immunity maintains occult cancer in an equilibrium state
    • DOI 10.1038/nature06309, PII NATURE06309
    • Koebel CM, Vermi W, Swann JB, Zerafa N, Rodig SJ, Old LJ, Smyth MJ, Schreiber RD. Adaptive immunity maintains occult cancer in an equilibrium state. Nature 2007; 450:903-7; PMID:18026089; http://dx.doi.org/10.1038/nature06309 (Pubitemid 350231320)
    • (2007) Nature , vol.450 , Issue.7171 , pp. 903-907
    • Koebel, C.M.1    Vermi, W.2    Swann, J.B.3    Zerafa, N.4    Rodig, S.J.5    Old, L.J.6    Smyth, M.J.7    Schreiber, R.D.8
  • 40
    • 0344622606 scopus 로고
    • The serial cultivation of human diploid cell strains
    • PMID:13905658
    • Hayflick L, Moorhead PS. The serial cultivation of human diploid cell strains. Exp Cell Res 1961; 25:585-621; PMID:13905658; http://dx.doi.org/10. 1016/0014-4827(61)90192-6
    • (1961) Exp Cell Res , vol.25 , pp. 585-621
    • Hayflick, L.1    Moorhead, P.S.2
  • 41
    • 34447543913 scopus 로고    scopus 로고
    • Cellular Senescence in Cancer and Aging
    • DOI 10.1016/j.cell.2007.07.003, PII S0092867407008902
    • Collado M, Blasco MA, Serrano M. Cellular senescence in cancer and aging. Cell 2007; 130:223-33; PMID:17662938; http://dx.doi.org/10.1016/j.cell.2007.07. 003 (Pubitemid 47081143)
    • (2007) Cell , vol.130 , Issue.2 , pp. 223-233
    • Collado, M.1    Blasco, M.A.2    Serrano, M.3
  • 42
    • 38849168162 scopus 로고    scopus 로고
    • Oncogenic BRAF Induces Senescence and Apoptosis through Pathways Mediated by the Secreted Protein IGFBP7
    • DOI 10.1016/j.cell.2007.12.032, PII S0092867408000536
    • Wajapeyee N, Serra RW, Zhu X, Mahalingam M, Green MR. Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7. Cell 2008; 132:363-74; PMID:18267069; http://dx.doi.org/10.1016/ j.cell.2007.12.032 (Pubitemid 351191995)
    • (2008) Cell , vol.132 , Issue.3 , pp. 363-374
    • Wajapeyee, N.1    Serra, R.W.2    Zhu, X.3    Mahalingam, M.4    Green, M.R.5
  • 43
    • 66649117243 scopus 로고    scopus 로고
    • F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage
    • PMID:19412162
    • Santra MK, Wajapeyee N, Green MR. F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage. Nature 2009; 459:722- 5; PMID:19412162; http://dx.doi.org/10.1038/nature08011
    • (2009) Nature , vol.459 , pp. 722-725
    • Santra, M.K.1    Wajapeyee, N.2    Green, M.R.3
  • 44
    • 84871608812 scopus 로고    scopus 로고
    • ROS-generating oxidases Nox1 and Nox4 contribute to oncogenic Ras-induced premature senescence
    • PMID:23216904
    • Kodama R, Kato M, Furuta S, Ueno S, Zhang Y, Matsuno K, Yabe-Nishimura C, Tanaka E, Kamata T. ROS-generating oxidases Nox1 and Nox4 contribute to oncogenic Ras-induced premature senescence. Genes Cells 2013; 18:32-41; PMID:23216904; http://dx.doi.org/10.1111/gtc.12015
    • (2013) Genes Cells , vol.18 , pp. 32-41
    • Kodama, R.1    Kato, M.2    Furuta, S.3    Ueno, S.4    Zhang, Y.5    Matsuno, K.6    Yabe-Nishimura, C.7    Tanaka, E.8    Kamata, T.9
  • 45
    • 84857784512 scopus 로고    scopus 로고
    • Senescence is an endogenous trigger for microRNAdirected transcriptional gene silencing in human cells
    • PMID:22366686
    • Benhamed M, Herbig U, Ye T, Dejean A, Bischof O. Senescence is an endogenous trigger for microRNAdirected transcriptional gene silencing in human cells. Nat Cell Biol 2012; 14:266-75; PMID:22366686; http://dx.doi.org/10.1038/ ncb2443
    • (2012) Nat Cell Biol , vol.14 , pp. 266-275
    • Benhamed, M.1    Herbig, U.2    Ye, T.3    Dejean, A.4    Bischof, O.5
  • 48
    • 84862891914 scopus 로고    scopus 로고
    • Cell cycle arrest is not yet senescence, which is not just cell cycle arrest: Terminology for TOR-driven aging
    • PMID:22394614
    • Blagosklonny MV. Cell cycle arrest is not yet senescence, which is not just cell cycle arrest: terminology for TOR-driven aging. Aging (Albany NY) 2012; 4:159-65; PMID:22394614
    • (2012) Aging (Albany NY) , vol.4 , pp. 159-165
    • Blagosklonny, M.V.1
  • 49
    • 79959637828 scopus 로고    scopus 로고
    • Pro-senescence therapy for cancer treatment
    • PMID:21701512
    • Nardella C, Clohessy JG, Alimonti A, Pandolfi PP. Pro-senescence therapy for cancer treatment. Nat Rev Cancer 2011; 11:503-11; PMID:21701512; http://dx.doi.org/10.1038/nrc3057
    • (2011) Nat Rev Cancer , vol.11 , pp. 503-511
    • Nardella, C.1    Clohessy, J.G.2    Alimonti, A.3    Pandolfi, P.P.4
  • 51
    • 79952392467 scopus 로고    scopus 로고
    • Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression
    • PMID:21383745
    • Bissell MJ, Hines WC. Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression. Nat Med 2011; 17:320- 9; PMID:21383745; http://dx.doi.org/10.1038/nm.2328
    • (2011) Nat Med , vol.17 , pp. 320-329
    • Bissell, M.J.1    Hines, W.C.2
  • 52
    • 78249257291 scopus 로고    scopus 로고
    • CD4(+) T cells contribute to the remodeling of the microenvironment required for sustained tumor regression upon oncogene inactivation
    • PMID:21035406
    • Rakhra K, Bachireddy P, Zabuawala T, Zeiser R, Xu L, Kopelman A, Fan AC, Yang Q, Braunstein L, Crosby E, et al. CD4(+) T cells contribute to the remodeling of the microenvironment required for sustained tumor regression upon oncogene inactivation. Cancer Cell 2010; 18:485-98; PMID:21035406; http://dx.doi.org/10.1016/j.ccr.2010.10.002
    • (2010) Cancer Cell , vol.18 , pp. 485-498
    • Rakhra, K.1    Bachireddy, P.2    Zabuawala, T.3    Zeiser, R.4    Xu, L.5    Kopelman, A.6    Fan, A.C.7    Yang, Q.8    Braunstein, L.9    Crosby, E.10
  • 54
    • 84872370561 scopus 로고    scopus 로고
    • Loss of p53 in enterocytes generates an inflammatory microenvironment enabling invasion and lymph node metastasis of carcinogen-induced colorectal tumors
    • PMID:23273920
    • Schwitalla S, Ziegler PK, Horst D, Becker V, Kerle I, Begus-Nahrmann Y, Lechel A, Rudolph KL, Langer R, Slotta-Huspenina J, et al. Loss of p53 in enterocytes generates an inflammatory microenvironment enabling invasion and lymph node metastasis of carcinogen-induced colorectal tumors. Cancer Cell 2013; 23:93-106; PMID:23273920; http://dx.doi.org/10.1016/j.ccr.2012.11.014
    • (2013) Cancer Cell , vol.23 , pp. 93-106
    • Schwitalla, S.1    Ziegler, P.K.2    Horst, D.3    Becker, V.4    Kerle, I.5    Begus-Nahrmann, Y.6    Lechel, A.7    Rudolph, K.L.8    Langer, R.9    Slotta-Huspenina, J.10
  • 55
    • 79951815749 scopus 로고    scopus 로고
    • Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer
    • PMID:21303976
    • Tosolini M, Kirilovsky A, Mlecnik B, Fredriksen T, Mauger S, Bindea G, Berger A, Bruneval P, Fridman WH, Pagès F, et al. Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer. Cancer Res 2011; 71:1263-71; PMID:21303976; http://dx.doi.org/10.1158/0008-5472.CAN-10-2907
    • (2011) Cancer Res , vol.71 , pp. 1263-1271
    • Tosolini, M.1    Kirilovsky, A.2    Mlecnik, B.3    Fredriksen, T.4    Mauger, S.5    Bindea, G.6    Berger, A.7    Bruneval, P.8    Fridman, W.H.9    Pagès, F.10
  • 58
    • 0022377333 scopus 로고
    • Characterization of receptors for human tumour necrosis factor and their regulation by γ-interferon
    • DOI 10.1038/318665a0
    • Aggarwal BB, Eessalu TE, Hass PE. Characterization of receptors for human tumour necrosis factor and their regulation by gamma-interferon. Nature 1985; 318:665-7; PMID:3001529; http://dx.doi.org/10.1038/318665a0 (Pubitemid 16172416)
    • (1985) Nature , vol.318 , Issue.6047 , pp. 665-667
    • Aggarwal, B.B.1    Eessalu, T.E.2    Hass, P.E.3
  • 59
    • 84859871183 scopus 로고    scopus 로고
    • Analyzing the pivotal trial that compared sunitinib and IFN-A in renal cell carcinoma, using a method that assesses tumor regression and growth
    • PMID:22344231
    • Stein WD, Wilkerson J, Kim ST, Huang X, Motzer RJ, Fojo AT, Bates SE. Analyzing the pivotal trial that compared sunitinib and IFN-a in renal cell carcinoma, using a method that assesses tumor regression and growth. Clin Cancer Res 2012; 18:2374-81; PMID:22344231; http://dx.doi.org/10.1158/1078- 0432.CCR-11-2275
    • (2012) Clin Cancer Res , vol.18 , pp. 2374-2381
    • Stein, W.D.1    Wilkerson, J.2    Kim, S.T.3    Huang, X.4    Motzer, R.J.5    Fojo, A.T.6    Bates, S.E.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.