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Volumn 19, Issue 6, 2013, Pages 926-932

Progressive improvement in wound healing with increased therapy in haemophilia B mice

Author keywords

Bleeding; Factor IX; Factor VIIa; Haemophilia; Mouse models; Wound healing

Indexed keywords

BLOOD CLOTTING FACTOR 7A; BLOOD CLOTTING FACTOR 9; IRON;

EID: 84886641038     PISSN: 13518216     EISSN: 13652516     Source Type: Journal    
DOI: 10.1111/hae.12220     Document Type: Article
Times cited : (8)

References (43)
  • 1
    • 0031009081 scopus 로고    scopus 로고
    • General principles of wound healing
    • Witte MB, Barbul A. General principles of wound healing. Surg Clin North Am 1997; 77: 509-28.
    • (1997) Surg Clin North Am , vol.77 , pp. 509-528
    • Witte, M.B.1    Barbul, A.2
  • 2
    • 0033517356 scopus 로고    scopus 로고
    • Cutaneous wound healing
    • Singer AJ, Clark RA. Cutaneous wound healing. N Engl J Med 1999; 341: 738-46.
    • (1999) N Engl J Med , vol.341 , pp. 738-746
    • Singer, A.J.1    Clark, R.A.2
  • 4
    • 0030007064 scopus 로고    scopus 로고
    • Impaired wound healing in mice with a disrupted plasminogen gene
    • Romer J, Bugge TH, Pyke C et al. Impaired wound healing in mice with a disrupted plasminogen gene. Nat Med 1996; 2: 287-92.
    • (1996) Nat Med , vol.2 , pp. 287-292
    • Romer, J.1    Bugge, T.H.2    Pyke, C.3
  • 5
    • 23744456948 scopus 로고    scopus 로고
    • Impaired wound healing in factor XIII deficient mice
    • Inbal A, Lubetsky A, Krapp T et al. Impaired wound healing in factor XIII deficient mice. Thromb Haemost 2005; 94: 432-7.
    • (2005) Thromb Haemost , vol.94 , pp. 432-437
    • Inbal, A.1    Lubetsky, A.2    Krapp, T.3
  • 7
    • 0027240440 scopus 로고
    • Thrombin stimulates fibroblast chemotaxis and replication
    • Dawes KE, Gray AJ, Laurent GJ. Thrombin stimulates fibroblast chemotaxis and replication. Eur J Cell Biol 1993; 61: 126-30.
    • (1993) Eur J Cell Biol , vol.61 , pp. 126-130
    • Dawes, K.E.1    Gray, A.J.2    Laurent, G.J.3
  • 8
    • 3042773692 scopus 로고    scopus 로고
    • Behavior of human dermal fibroblasts in three-dimensional fibrin clots: dependence on fibrinogen and thrombin concentration
    • Cox S, Cole M, Tawil B. Behavior of human dermal fibroblasts in three-dimensional fibrin clots: dependence on fibrinogen and thrombin concentration. Tissue Eng 2004; 10: 942-54.
    • (2004) Tissue Eng , vol.10 , pp. 942-954
    • Cox, S.1    Cole, M.2    Tawil, B.3
  • 9
    • 0026035523 scopus 로고
    • Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
    • Vu TK, Hung DT, Wheaton VI, Coughlin SR. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 1991; 64: 1057-68.
    • (1991) Cell , vol.64 , pp. 1057-1068
    • Vu, T.K.1    Hung, D.T.2    Wheaton, V.I.3    Coughlin, S.R.4
  • 10
    • 0034581330 scopus 로고    scopus 로고
    • Thrombin peptide, TP508, stimulates angiogenic responses in animal models of dermal wound healing, in chick chorioallantoic membranes, and in cultured human aortic and microvascular endothelial cells
    • Norfleet AM, Bergmann JS, Carney DH. Thrombin peptide, TP508, stimulates angiogenic responses in animal models of dermal wound healing, in chick chorioallantoic membranes, and in cultured human aortic and microvascular endothelial cells. Gen Pharmacol 2000; 35: 249-54.
    • (2000) Gen Pharmacol , vol.35 , pp. 249-254
    • Norfleet, A.M.1    Bergmann, J.S.2    Carney, D.H.3
  • 11
    • 0034779690 scopus 로고    scopus 로고
    • Immobilized thrombin receptor agonist peptide accelerates wound healing in mice
    • Strukova SM, Dugina TN, Chistov IV et al. Immobilized thrombin receptor agonist peptide accelerates wound healing in mice. Clin Appl Thromb Hemost 2001; 7: 325-9.
    • (2001) Clin Appl Thromb Hemost , vol.7 , pp. 325-329
    • Strukova, S.M.1    Dugina, T.N.2    Chistov, I.V.3
  • 12
    • 33846541231 scopus 로고    scopus 로고
    • Protease activated receptors: clinical relevance to hemostasis and inflammation
    • Landis RC. Protease activated receptors: clinical relevance to hemostasis and inflammation. Hematol Oncol Clin North Am 2007; 21: 103-13.
    • (2007) Hematol Oncol Clin North Am , vol.21 , pp. 103-113
    • Landis, R.C.1
  • 13
    • 0021683480 scopus 로고
    • The haemostatic plug in haemophilia A: a morphological study of haemostatic plug formation in bleeding time skin wounds of patients with severe haemophilia A
    • Sixma JJ, van den Berg A. The haemostatic plug in haemophilia A: a morphological study of haemostatic plug formation in bleeding time skin wounds of patients with severe haemophilia A. Br J Haematol 1984; 58: 741-53.
    • (1984) Br J Haematol , vol.58 , pp. 741-753
    • Sixma, J.J.1    van den Berg, A.2
  • 14
    • 84863549752 scopus 로고    scopus 로고
    • The clotting system - a major player in wound healing
    • Monroe DM, Hoffman M. The clotting system - a major player in wound healing. Haemophilia 2012; 18(Suppl 5): 11-6.
    • (2012) Haemophilia , vol.18 , Issue.SUPPL. 5 , pp. 11-16
    • Monroe, D.M.1    Hoffman, M.2
  • 18
    • 33750209018 scopus 로고    scopus 로고
    • Altered fibrin architecture is associated with hypofibrinolysis and premature coronary atherothrombosis
    • Collet JP, Allali Y, Lesty C et al. Altered fibrin architecture is associated with hypofibrinolysis and premature coronary atherothrombosis. Arterioscler Thromb Vasc Biol 2006; 26: 2567-73.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 2567-2573
    • Collet, J.P.1    Allali, Y.2    Lesty, C.3
  • 19
    • 77952084799 scopus 로고    scopus 로고
    • The direct thrombin inhibitors (argatroban, bivalirudin and lepirudin) and the indirect Xa-inhibitor (danaparoid) increase fibrin network porosity and thus facilitate fibrinolysis
    • He S, Blombäck M, Bark N, Johnsson H, Wallén NH. The direct thrombin inhibitors (argatroban, bivalirudin and lepirudin) and the indirect Xa-inhibitor (danaparoid) increase fibrin network porosity and thus facilitate fibrinolysis. Thromb Haemost 2010; 103: 1076-84.
    • (2010) Thromb Haemost , vol.103 , pp. 1076-1084
    • He, S.1    Blombäck, M.2    Bark, N.3    Johnsson, H.4    Wallén, N.H.5
  • 20
    • 34047229067 scopus 로고    scopus 로고
    • Thrombin generation and fibrin clot structure
    • Wolberg AS. Thrombin generation and fibrin clot structure. Blood Rev 2007; 21: 131-42.
    • (2007) Blood Rev , vol.21 , pp. 131-142
    • Wolberg, A.S.1
  • 21
    • 34447648526 scopus 로고    scopus 로고
    • Restoring hemostatic thrombin generation at the time of cutaneous wounding does not normalize healing in hemophilia B
    • McDonald A, Hoffman M, Hedner U, Roberts HR, Monroe DM. Restoring hemostatic thrombin generation at the time of cutaneous wounding does not normalize healing in hemophilia B. J Thromb Haemost 2007; 5: 1577-83.
    • (2007) J Thromb Haemost , vol.5 , pp. 1577-1583
    • McDonald, A.1    Hoffman, M.2    Hedner, U.3    Roberts, H.R.4    Monroe, D.M.5
  • 22
    • 0015138090 scopus 로고
    • Clinical experience with a Swedish factor IX concentrate
    • Nilsson IM, Ahlberg A, Björlin G. Clinical experience with a Swedish factor IX concentrate. Acta Med Scand 1971; 190: 257-66.
    • (1971) Acta Med Scand , vol.190 , pp. 257-266
    • Nilsson, I.M.1    Ahlberg, A.2    Björlin, G.3
  • 23
    • 84863190270 scopus 로고    scopus 로고
    • Surgical wound healing in bleeding disorders
    • Rodriguez-Merchan EC. Surgical wound healing in bleeding disorders. Haemophilia 2012; 18: 487-90.
    • (2012) Haemophilia , vol.18 , pp. 487-490
    • Rodriguez-Merchan, E.C.1
  • 24
    • 0019962385 scopus 로고
    • Management of fractures in hemophilia
    • Wolff LJ, Lovrien EW. Management of fractures in hemophilia. Pediatrics 1982; 70: 431-6.
    • (1982) Pediatrics , vol.70 , pp. 431-436
    • Wolff, L.J.1    Lovrien, E.W.2
  • 25
    • 0036489646 scopus 로고    scopus 로고
    • Bone fractures in the haemophilic patient
    • Rodriguez-Merchan EC. Bone fractures in the haemophilic patient. Haemophilia 2002; 8: 104-11.
    • (2002) Haemophilia , vol.8 , pp. 104-111
    • Rodriguez-Merchan, E.C.1
  • 26
    • 0030817391 scopus 로고    scopus 로고
    • A coagulation factor IX-deficient mouse model for human hemophilia B
    • Lin HF, Maeda N, Smithies O, Straight DL, Stafford DW. A coagulation factor IX-deficient mouse model for human hemophilia B. Blood 1997; 90: 3962-6.
    • (1997) Blood , vol.90 , pp. 3962-3966
    • Lin, H.F.1    Maeda, N.2    Smithies, O.3    Straight, D.L.4    Stafford, D.W.5
  • 27
    • 0242494903 scopus 로고    scopus 로고
    • Improved hemostasis with superactive analogs of factor VIIa in a mouse model of hemophilia A
    • Tranholm M, Kristensen K, Kristensen AT, Pyke C, Røjkjaer R, Persson E. Improved hemostasis with superactive analogs of factor VIIa in a mouse model of hemophilia A. Blood 2003; 102: 3615-20.
    • (2003) Blood , vol.102 , pp. 3615-3620
    • Tranholm, M.1    Kristensen, K.2    Kristensen, A.T.3    Pyke, C.4    Røjkjaer, R.5    Persson, E.6
  • 28
    • 0036660414 scopus 로고    scopus 로고
    • Circulating and binding characteristics of wild-type factor IX and certain Gla domain mutants in vivo
    • Gui T, Lin H-F, Jin D-Y et al. Circulating and binding characteristics of wild-type factor IX and certain Gla domain mutants in vivo. Blood 2002; 100: 153-8.
    • (2002) Blood , vol.100 , pp. 153-158
    • Gui, T.1    Lin, H.-F.2    Jin, D.-Y.3
  • 29
    • 1442350295 scopus 로고    scopus 로고
    • Potential role of recombinant factor VIIa as a hemostatic agent
    • Hedner U, Erhardtsen E. Potential role of recombinant factor VIIa as a hemostatic agent. Clin Adv Hematol Oncol 2003; 1: 112-9.
    • (2003) Clin Adv Hematol Oncol , vol.1 , pp. 112-119
    • Hedner, U.1    Erhardtsen, E.2
  • 30
    • 84868159252 scopus 로고    scopus 로고
    • Endothelial cell protein C receptor-mediated redistribution and tissue-level accumulation of factor VIIa
    • Clark CA, Vatsyayan R, Hedner U, Esmon CT, Pendurthi UR, Rao LVM. Endothelial cell protein C receptor-mediated redistribution and tissue-level accumulation of factor VIIa. J Thromb Haemost 2012; 10: 2383-91.
    • (2012) J Thromb Haemost , vol.10 , pp. 2383-2391
    • Clark, C.A.1    Vatsyayan, R.2    Hedner, U.3    Esmon, C.T.4    Pendurthi, U.R.5    Rao, L.V.M.6
  • 31
    • 0000642942 scopus 로고
    • Some Methods for Strengthening the Common χ2 Tests
    • Cochran WG. Some Methods for Strengthening the Common χ2 Tests. Biometrics 1954; 10: 417-51.
    • (1954) Biometrics , vol.10 , pp. 417-451
    • Cochran, W.G.1
  • 32
    • 0000937686 scopus 로고
    • Tests for Linear Trends in Proportions and Frequencies
    • Armitage P. Tests for Linear Trends in Proportions and Frequencies. Biometrics 1955; 11: 375-86.
    • (1955) Biometrics , vol.11 , pp. 375-386
    • Armitage, P.1
  • 33
    • 0032005213 scopus 로고    scopus 로고
    • Human factor IX corrects the bleeding diathesis of mice with hemophilia B
    • Kung SH, Hagstrom JN, Cass D et al. Human factor IX corrects the bleeding diathesis of mice with hemophilia B. Blood 1998; 91: 784-90.
    • (1998) Blood , vol.91 , pp. 784-790
    • Kung, S.H.1    Hagstrom, J.N.2    Cass, D.3
  • 34
    • 17444416465 scopus 로고    scopus 로고
    • Characterization of recombinant murine factor VIIa and recombinant murine tissue factor: a human-murine species compatibility study
    • Petersen LC, Nørby PL, Branner S et al. Characterization of recombinant murine factor VIIa and recombinant murine tissue factor: a human-murine species compatibility study. Thromb Res 2005; 116: 75-85.
    • (2005) Thromb Res , vol.116 , pp. 75-85
    • Petersen, L.C.1    Nørby, P.L.2    Branner, S.3
  • 35
    • 0036359416 scopus 로고    scopus 로고
    • Factor VIIa/tissue factor-induced signaling: a link between clotting and disease
    • Pendurthi UR, Rao LVM. Factor VIIa/tissue factor-induced signaling: a link between clotting and disease. Vitam Horm 2002; 64: 323-55.
    • (2002) Vitam Horm , vol.64 , pp. 323-355
    • Pendurthi, U.R.1    Rao, L.V.M.2
  • 36
    • 0141498162 scopus 로고    scopus 로고
    • Specificity of coagulation factor signaling
    • Ruf W, Dorfleutner A, Riewald M. Specificity of coagulation factor signaling. J Thromb Haemost 2003; 1: 1495-503.
    • (2003) J Thromb Haemost , vol.1 , pp. 1495-1503
    • Ruf, W.1    Dorfleutner, A.2    Riewald, M.3
  • 38
    • 74749095228 scopus 로고    scopus 로고
    • Bio-distribution of pharmacologically administered recombinant factor VIIa (rFVIIa)
    • Gopalakrishnan R, Hedner U, Ghosh S et al. Bio-distribution of pharmacologically administered recombinant factor VIIa (rFVIIa). J Thromb Haemost 2010; 8: 301-10.
    • (2010) J Thromb Haemost , vol.8 , pp. 301-310
    • Gopalakrishnan, R.1    Hedner, U.2    Ghosh, S.3
  • 39
    • 1842474888 scopus 로고    scopus 로고
    • Tissue factor-factor VIIa-specific up-regulation of IL-8 expression in MDA-MB-231 cells is mediated by PAR-2 and results in increased cell migration
    • Hjortoe GM, Petersen LC, Albrektsen T et al. Tissue factor-factor VIIa-specific up-regulation of IL-8 expression in MDA-MB-231 cells is mediated by PAR-2 and results in increased cell migration. Blood 2004; 103: 3029-37.
    • (2004) Blood , vol.103 , pp. 3029-3037
    • Hjortoe, G.M.1    Petersen, L.C.2    Albrektsen, T.3
  • 40
    • 65449158359 scopus 로고    scopus 로고
    • Single-dose (270 microg kg(-1)) recombinant activated factor VII for the treatment and prevention of bleeds in haemophilia A patients with inhibitors: experience from seven European haemophilia centres
    • Pan-Petesch B, Laguna P, Mital A et al. Single-dose (270 microg kg(-1)) recombinant activated factor VII for the treatment and prevention of bleeds in haemophilia A patients with inhibitors: experience from seven European haemophilia centres. Haemophilia 2009; 15: 760-5.
    • (2009) Haemophilia , vol.15 , pp. 760-765
    • Pan-Petesch, B.1    Laguna, P.2    Mital, A.3
  • 41
    • 0036090268 scopus 로고    scopus 로고
    • Inhibition of fibrinolysis by recombinant factor VIIa in plasma from patients with severe hemophilia A
    • Lisman T, Mosnier LO, Lambert T et al. Inhibition of fibrinolysis by recombinant factor VIIa in plasma from patients with severe hemophilia A. Blood 2002; 99: 175-9.
    • (2002) Blood , vol.99 , pp. 175-179
    • Lisman, T.1    Mosnier, L.O.2    Lambert, T.3
  • 42
    • 36348983304 scopus 로고    scopus 로고
    • Tranexamic acid combined with recombinant factor VIII increases clot resistance to accelerated fibrinolysis in severe hemophilia A
    • Hvas A-M, Sørensen HT, Norengaard L, Christiansen K, Ingerslev J, Sørensen B. Tranexamic acid combined with recombinant factor VIII increases clot resistance to accelerated fibrinolysis in severe hemophilia A. J Thromb Haemost 2007; 5: 2408-14.
    • (2007) J Thromb Haemost , vol.5 , pp. 2408-2414
    • Hvas, A.-M.1    Sørensen, H.T.2    Norengaard, L.3    Christiansen, K.4    Ingerslev, J.5    Sørensen, B.6
  • 43
    • 0036185991 scopus 로고    scopus 로고
    • Nitric oxide drives skin repair: novel functions of an established mediator
    • Frank S, Kämpfer H, Wetzler C, Pfeilschifter J. Nitric oxide drives skin repair: novel functions of an established mediator. Kidney Int 2002; 61: 882-8.
    • (2002) Kidney Int , vol.61 , pp. 882-888
    • Frank, S.1    Kämpfer, H.2    Wetzler, C.3    Pfeilschifter, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.