-
1
-
-
0024997547
-
Factor IX is activated in vivo by the tissue factor mechanism
-
Bauer KA, Kass BL, Ten Cate H, Hawiger JJ, Rosenberg RD. Factor IX is activated in vivo by the tissue factor mechanism. Blood 1990; 76: 731-6.
-
(1990)
Blood
, vol.76
, pp. 731-736
-
-
Bauer, K.A.1
Kass, B.L.2
Ten Cate, H.3
Hawiger, J.J.4
Rosenberg, R.D.5
-
2
-
-
0024444125
-
Detection of factor X activation in humans
-
Bauer KA, Kass BL, Ten Cate H, Bednarek MA, Hawiger JJ, Rosenberg RD. Detection of factor X activation in humans. Blood 1989; 74: 2007-15.
-
(1989)
Blood
, vol.74
, pp. 2007-2015
-
-
Bauer, K.A.1
Kass, B.L.2
Ten Cate, H.3
Bednarek, M.A.4
Hawiger, J.J.5
Rosenberg, R.D.6
-
3
-
-
0027302704
-
The activation of factor X and prothrombin by recombinant factor VIIa in vivo is mediated by tissue factor
-
Ten Cate H, Bauer K, Levi M, Edgington TS, Sublett RD, Barzegar S, Kass B, Rosenberg RD. The activation of factor X and prothrombin by recombinant factor VIIa in vivo is mediated by tissue factor. J Clin Invest 1993; 92: 1207-12.
-
(1993)
J Clin Invest
, vol.92
, pp. 1207-1212
-
-
Ten Cate, H.1
Bauer, K.2
Levi, M.3
Edgington, T.S.4
Sublett, R.D.5
Barzegar, S.6
Kass, B.7
Rosenberg, R.D.8
-
4
-
-
15944404600
-
Tissue factor activity in whole blood
-
Butenas S, Bouchard BA, Brummel-Ziedins KE, Parhami-Seren B, Mann KG. Tissue factor activity in whole blood. Blood 2005; 105: 2764-70.
-
(2005)
Blood
, vol.105
, pp. 2764-2770
-
-
Butenas, S.1
Bouchard, B.A.2
Brummel-Ziedins, K.E.3
Parhami-Seren, B.4
Mann, K.G.5
-
5
-
-
39649106357
-
Tissue factor and factor VIIa as therapeutic targets in disorders of hemostasis
-
Hedner U, Ezban M. Tissue factor and factor VIIa as therapeutic targets in disorders of hemostasis. Annu Rev Med 2008; 59: 29-41.
-
(2008)
Annu Rev Med
, vol.59
, pp. 29-41
-
-
Hedner, U.1
Ezban, M.2
-
6
-
-
0034758420
-
Effective prophylaxis with daily recombinant factor VIIa (rFVIIa-Novoseven) in a child with high titre inhibitors and a target joint
-
Saxon BR, Shanks D, Jory CB, Williams V. Effective prophylaxis with daily recombinant factor VIIa (rFVIIa-Novoseven) in a child with high titre inhibitors and a target joint. Thromb Haemost 2001; 86: 1126-7.
-
(2001)
Thromb Haemost
, vol.86
, pp. 1126-1127
-
-
Saxon, B.R.1
Shanks, D.2
Jory, C.B.3
Williams, V.4
-
7
-
-
19444375983
-
Prophylactic recombinant factor VIIa in haemophilia patients with inhibitors
-
Young G, McDaniel M, Nugent DJ. Prophylactic recombinant factor VIIa in haemophilia patients with inhibitors. Haemophilia 2005; 11: 203-7.
-
(2005)
Haemophilia
, vol.11
, pp. 203-207
-
-
Young, G.1
McDaniel, M.2
Nugent, D.J.3
-
8
-
-
51249100418
-
Prophylaxis with recombinant factor VIIa for the management of bleeding episodes during immune tolerance treatment in a boy with severe haemophilia A and high-response inhibitors
-
Blatny J, Kohlerova S, Zapletal O, Fiamoli V, Penka M, Smith O. Prophylaxis with recombinant factor VIIa for the management of bleeding episodes during immune tolerance treatment in a boy with severe haemophilia A and high-response inhibitors. Haemophilia 2008; 14: 1140-2.
-
(2008)
Haemophilia
, vol.14
, pp. 1140-1142
-
-
Blatny, J.1
Kohlerova, S.2
Zapletal, O.3
Fiamoli, V.4
Penka, M.5
Smith, O.6
-
9
-
-
34548301664
-
Prophylactic treatment of haemophilia patients with inhibitors: clinical experience with recombinant factor VIIa in European Haemophilia Centres
-
Morfini M, Auerswald G, Kobelt RA, Rivolta GF, Rodriguez-Martorell J, Scaraggi FA, Altisent C, Blatny J, Borel-Derlon A, Rossi V. Prophylactic treatment of haemophilia patients with inhibitors: clinical experience with recombinant factor VIIa in European Haemophilia Centres. Haemophilia 2007; 13: 502-7.
-
(2007)
Haemophilia
, vol.13
, pp. 502-507
-
-
Morfini, M.1
Auerswald, G.2
Kobelt, R.A.3
Rivolta, G.F.4
Rodriguez-Martorell, J.5
Scaraggi, F.A.6
Altisent, C.7
Blatny, J.8
Borel-Derlon, A.9
Rossi, V.10
-
10
-
-
2342649465
-
Recombinant factor VIIa prophylaxis in a patient with severe congenital factor VII deficiency
-
Tcheng WY, Donkin J, Konzal S, Wong WY. Recombinant factor VIIa prophylaxis in a patient with severe congenital factor VII deficiency. Haemophilia 2004; 10: 295-8.
-
(2004)
Haemophilia
, vol.10
, pp. 295-298
-
-
Tcheng, W.Y.1
Donkin, J.2
Konzal, S.3
Wong, W.Y.4
-
11
-
-
3142739015
-
Prophylactic effect of recombinant factor VIIa in factor VII deficient patients
-
Mathijssen NC, Masereeuw R, Verbeek K, Lavergne JM, Costa JM, van Heerde WL, Novakova IR. Prophylactic effect of recombinant factor VIIa in factor VII deficient patients. Br J Haematol 2004; 125: 494-9.
-
(2004)
Br J Haematol
, vol.125
, pp. 494-499
-
-
Mathijssen, N.C.1
Masereeuw, R.2
Verbeek, K.3
Lavergne, J.M.4
Costa, J.M.5
van Heerde, W.L.6
Novakova, I.R.7
-
12
-
-
34548096392
-
Randomized, prospective clinical trial of recombinant factor VIIa for secondary prophylaxis in hemophilia patients with inhibitors
-
Konkle BA, Ebbesen LS, Erhardtsen E, Bianco RP, Lissitchkov T, Rusen L, Serban MA. Randomized, prospective clinical trial of recombinant factor VIIa for secondary prophylaxis in hemophilia patients with inhibitors. J Thromb Haemost 2007; 5: 1904-13.
-
(2007)
J Thromb Haemost
, vol.5
, pp. 1904-1913
-
-
Konkle, B.A.1
Ebbesen, L.S.2
Erhardtsen, E.3
Bianco, R.P.4
Lissitchkov, T.5
Rusen, L.6
Serban, M.A.7
-
13
-
-
34249722192
-
Endothelial cell protein C receptor acts as a cellular receptor for factor VIIa on endothelium
-
Ghosh S, Pendurthi UR, Steinoe A, Esmon CT, Rao LV. Endothelial cell protein C receptor acts as a cellular receptor for factor VIIa on endothelium. J Biol Chem 2007; 282: 11849-57.
-
(2007)
J Biol Chem
, vol.282
, pp. 11849-11857
-
-
Ghosh, S.1
Pendurthi, U.R.2
Steinoe, A.3
Esmon, C.T.4
Rao, L.V.5
-
14
-
-
33749378618
-
Multifunctional specificity of the protein C/activated protein C Gla domain
-
Preston RJ, Ajzner E, Razzari C, Karageorgi S, Dua S, Dahlback B, Lane DA. Multifunctional specificity of the protein C/activated protein C Gla domain. J Biol Chem 2006; 281: 28850-7.
-
(2006)
J Biol Chem
, vol.281
, pp. 28850-28857
-
-
Preston, R.J.1
Ajzner, E.2
Razzari, C.3
Karageorgi, S.4
Dua, S.5
Dahlback, B.6
Lane, D.A.7
-
15
-
-
34548076281
-
Binding of factor VIIa to the endothelial cell protein C receptor reduces its coagulant activity
-
Lopez-Sagaseta J, Montes R, Puy C, Diez N, Fukudome K, Hermida J. Binding of factor VIIa to the endothelial cell protein C receptor reduces its coagulant activity. J Thromb Haemost 2007; 5: 1817-24.
-
(2007)
J Thromb Haemost
, vol.5
, pp. 1817-1824
-
-
Lopez-Sagaseta, J.1
Montes, R.2
Puy, C.3
Diez, N.4
Fukudome, K.5
Hermida, J.6
-
16
-
-
79953092222
-
Factor VIIa bound to endothelial cell protein C receptor activates protease activated receptor-1 and mediates cell signaling and barrier protection
-
Sen P, Gopalakrishnan R, Kothari H, Keshava S, Clark CA, Esmon CT, Pendurthi UR, Rao LV. Factor VIIa bound to endothelial cell protein C receptor activates protease activated receptor-1 and mediates cell signaling and barrier protection. Blood 2011; 117: 3199-208.
-
(2011)
Blood
, vol.117
, pp. 3199-3208
-
-
Sen, P.1
Gopalakrishnan, R.2
Kothari, H.3
Keshava, S.4
Clark, C.A.5
Esmon, C.T.6
Pendurthi, U.R.7
Rao, L.V.8
-
17
-
-
70349263943
-
Endothelial cell protein C receptor cellular localization and trafficking
-
Nayak RC, Sen P, Ghosh S, Gopalakrishnan R, Esmon CT, Pendurthi UR, Rao LVM. Endothelial cell protein C receptor cellular localization and trafficking. Blood 2009; 114: 1974-86.
-
(2009)
Blood
, vol.114
, pp. 1974-1986
-
-
Nayak, R.C.1
Sen, P.2
Ghosh, S.3
Gopalakrishnan, R.4
Esmon, C.T.5
Pendurthi, U.R.6
Rao, L.V.M.7
-
18
-
-
74749095228
-
Bio-distribution of pharmacologically administered rFVIIa
-
Gopalakrishnan R, Hedner U, Ghosh S, Nayak R, Allen TC, Pendurthi UR, Rao LV. Bio-distribution of pharmacologically administered rFVIIa. J Thromb Haemost 2010; 8: 301-10.
-
(2010)
J Thromb Haemost
, vol.8
, pp. 301-310
-
-
Gopalakrishnan, R.1
Hedner, U.2
Ghosh, S.3
Nayak, R.4
Allen, T.C.5
Pendurthi, U.R.6
Rao, L.V.7
-
19
-
-
84860449128
-
Factor VIIa binding to endothelial cell protien C receptor: differences between mouse and human systems
-
Sen P, Clark CA, Gopalakrishnan R, Hedner U, Esmon CT, Pendurthi UR, Rao LVM. Factor VIIa binding to endothelial cell protien C receptor: differences between mouse and human systems. Thromb Haemost 2012; 107: 951-61.
-
(2012)
Thromb Haemost
, vol.107
, pp. 951-961
-
-
Sen, P.1
Clark, C.A.2
Gopalakrishnan, R.3
Hedner, U.4
Esmon, C.T.5
Pendurthi, U.R.6
Rao, L.V.M.7
-
20
-
-
0034161458
-
Endotoxin and thrombin elevate rodent endothelial cell protein C receptor mRNA levels and increase receptor shedding in vivo
-
Gu JM, Katsuura Y, Ferrell GL, Grammas P, Esmon CT. Endotoxin and thrombin elevate rodent endothelial cell protein C receptor mRNA levels and increase receptor shedding in vivo. Blood 2000; 95: 1687-93.
-
(2000)
Blood
, vol.95
, pp. 1687-1693
-
-
Gu, J.M.1
Katsuura, Y.2
Ferrell, G.L.3
Grammas, P.4
Esmon, C.T.5
-
21
-
-
27144449028
-
Extraembryonic expression of EPCR is essential for embryonic viability
-
Li W, Zheng X, Gu JM, Ferrell GL, Brady M, Esmon NL, Esmon CT. Extraembryonic expression of EPCR is essential for embryonic viability. Blood 2005; 106: 2716-22.
-
(2005)
Blood
, vol.106
, pp. 2716-2722
-
-
Li, W.1
Zheng, X.2
Gu, J.M.3
Ferrell, G.L.4
Brady, M.5
Esmon, N.L.6
Esmon, C.T.7
-
22
-
-
25144462156
-
Overexpressing endothelial cell protein C receptor alters the hemostatic balance and protects mice from endotoxin
-
Li W, Zheng X, Gu J, Hunter J, Ferrell GL, Lupu F, Esmon NL, Esmon CT. Overexpressing endothelial cell protein C receptor alters the hemostatic balance and protects mice from endotoxin. J Thromb Haemost 2005; 3: 1351-9.
-
(2005)
J Thromb Haemost
, vol.3
, pp. 1351-1359
-
-
Li, W.1
Zheng, X.2
Gu, J.3
Hunter, J.4
Ferrell, G.L.5
Lupu, F.6
Esmon, N.L.7
Esmon, C.T.8
-
23
-
-
0027402655
-
Quantitation of activated factor VII levels in plasma using a tissue factor mutant selectively deficient in promoting factor VII activation
-
Morrissey JH, Macik BG, Neuenschwander PF, Comp PC. Quantitation of activated factor VII levels in plasma using a tissue factor mutant selectively deficient in promoting factor VII activation. Blood 1993; 81: 734-44.
-
(1993)
Blood
, vol.81
, pp. 734-744
-
-
Morrissey, J.H.1
Macik, B.G.2
Neuenschwander, P.F.3
Comp, P.C.4
-
24
-
-
66149175575
-
Plasma elimination kinetics for factor VII are independent of its activation to factor VIIa and complex formation with plasma inhibitors
-
Petersen LC, Elm T, Ezban M, Krogh TN, Karpf DM, Steino A, Olsen EH, Sorensen BB. Plasma elimination kinetics for factor VII are independent of its activation to factor VIIa and complex formation with plasma inhibitors. Thromb Haemost 2009; 101: 818-26.
-
(2009)
Thromb Haemost
, vol.101
, pp. 818-826
-
-
Petersen, L.C.1
Elm, T.2
Ezban, M.3
Krogh, T.N.4
Karpf, D.M.5
Steino, A.6
Olsen, E.H.7
Sorensen, B.B.8
-
25
-
-
84860425038
-
Influence of endothelial cell protein C receptor on plasma clearance of factor VIIa
-
Gopalakrishnan R, Pendurthi UR, Hedner U, Agerso H, Esmon CT, Rao LV. Influence of endothelial cell protein C receptor on plasma clearance of factor VIIa. J Thromb Haemost 2012; 10: 971-3.
-
(2012)
J Thromb Haemost
, vol.10
, pp. 971-973
-
-
Gopalakrishnan, R.1
Pendurthi, U.R.2
Hedner, U.3
Agerso, H.4
Esmon, C.T.5
Rao, L.V.6
-
26
-
-
0027393872
-
Regulation of factor VIIa/tissue factor functional activity in an umbilical vein model
-
Almus FE, Rao LVM, Rapaport SI. Regulation of factor VIIa/tissue factor functional activity in an umbilical vein model. Arterioscler Thromb 1993; 13: 105-11.
-
(1993)
Arterioscler Thromb
, vol.13
, pp. 105-111
-
-
Almus, F.E.1
Rao, L.V.M.2
Rapaport, S.I.3
-
27
-
-
0025369735
-
Properties of factor VIIa/tissue factor complexes in an umbilical vein model
-
Almus FE, Rao LVM, Fleck RA, Rapaport SI. Properties of factor VIIa/tissue factor complexes in an umbilical vein model. Blood 1990; 76: 354-60.
-
(1990)
Blood
, vol.76
, pp. 354-360
-
-
Almus, F.E.1
Rao, L.V.M.2
Fleck, R.A.3
Rapaport, S.I.4
-
28
-
-
34250716379
-
Tissue factor around dermal vessels has bound factor VII in the absence of injury
-
Hoffman M, Colina CM, McDonald AG, Arepally GM, Pedersen L, Monroe DM. Tissue factor around dermal vessels has bound factor VII in the absence of injury. J Thromb Haemost 2007; 5: 1403-8.
-
(2007)
J Thromb Haemost
, vol.5
, pp. 1403-1408
-
-
Hoffman, M.1
Colina, C.M.2
McDonald, A.G.3
Arepally, G.M.4
Pedersen, L.5
Monroe, D.M.6
-
29
-
-
84857064170
-
The endothelial cell protein C receptor: cell surface conductor of cytoprotective coagulation factor signaling
-
Gleeson EM, O'Donnell JS, Preston RJ. The endothelial cell protein C receptor: cell surface conductor of cytoprotective coagulation factor signaling. Cell Mol Life Sci 2012; 69: 717-26.
-
(2012)
Cell Mol Life Sci
, vol.69
, pp. 717-726
-
-
Gleeson, E.M.1
O'Donnell, J.S.2
Preston, R.J.3
-
30
-
-
77949267709
-
Factor VIIa interaction with endothelial cells and endothelial cell protein C receptor
-
Pendurthi UR, Rao LV. Factor VIIa interaction with endothelial cells and endothelial cell protein C receptor. Thromb Res 2010; 125(Suppl. 1): S19-22.
-
(2010)
Thromb Res
, vol.125
, Issue.SUPPL. 1
-
-
Pendurthi, U.R.1
Rao, L.V.2
-
32
-
-
77950249545
-
Effect of glycoPEGylation on factor VIIa binding and internalization
-
Sen P, Ghosh S, Ezban M, Pendurthi UR, Vijaya Mohan RL. Effect of glycoPEGylation on factor VIIa binding and internalization. Haemophilia 2010; 16: 339-48.
-
(2010)
Haemophilia
, vol.16
, pp. 339-348
-
-
Sen, P.1
Ghosh, S.2
Ezban, M.3
Pendurthi, U.R.4
Vijaya Mohan, R.L.5
-
33
-
-
79960392729
-
Prolonged half-life of glycoPEGylated rFVIIa variants compared to native rFVIIa
-
Karpf DM, Sorensen BB, Hermit MB, Holmberg HL, Tranholm M, Bysted BV, Groth AV, Bjorn SE, Stennicke HR. Prolonged half-life of glycoPEGylated rFVIIa variants compared to native rFVIIa. Thromb Res 2011; 128: 191-5.
-
(2011)
Thromb Res
, vol.128
, pp. 191-195
-
-
Karpf, D.M.1
Sorensen, B.B.2
Hermit, M.B.3
Holmberg, H.L.4
Tranholm, M.5
Bysted, B.V.6
Groth, A.V.7
Bjorn, S.E.8
Stennicke, H.R.9
|