Restoring hemostatic thrombin generation at the time of cutaneous wounding does not normalize healing in hemophilia B

Journal of Thrombosis and Haemostasis

Volumn 5, Issue 8, 2007, Pages 1577-1583

  McDonald, A ^a   Hoffman, Maureane ^a,c   Hedner, U ^a,b   Roberts, H R ^a   Monroe, D M ^a  

^a DUKE UNIVERSITY   (United States)

^b NOVO NORDISK A S   (Denmark)

^c DURHAM VA MEDICAL CENTER   (United States)

Author keywords

Angiogenesis; Hemophilia; Hemorrhage; Thrombin; Wound healing

Indexed keywords

BLOOD CLOTTING FACTOR 9 CONCENTRATE; RECOMBINANT BLOOD CLOTTING FACTOR 7A; THROMBIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; FIBRIN CLOT; HEMATOMA; HEMOPHILIA B; HEMOSTASIS; HYPOTHESIS; MOUSE; NONHUMAN; PRIMARY PREVENTION; PRIORITY JOURNAL; SINGLE DRUG DOSE; SKIN BLEEDING; SKIN INJURY; WILD TYPE; WOUND CLOSURE; WOUND HEALING IMPAIRMENT;

ANIMALS; FACTOR IX; FACTOR VIIA; HEMOPHILIA A; HEMOPHILIA B; HEMORRHAGE; HEMOSTASIS; HUMANS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEOVASCULARIZATION, PHYSIOLOGIC; SKIN; THROMBIN; WOUND HEALING;

EID: 34447648526     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2007.02647.x     Document Type: Article

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