Development of a continuous-flow polymerase chain reaction device utilizing a polymer disk with a spiral microchannel of gradually varying width

Sensors and Actuators, B: Chemical

Volumn 191, Issue , 2014, Pages 75-85

  Chung, Kwang Hyo ^a   Choi, Yo Han ^a   Park, Seho ^b  

^a Electronics and Telecommunications Research Institute (ETRI)   (South Korea)

^b Gwangju Institute of Science and Technology (GIST)   (South Korea)

Author keywords

CFD simulation; Continuous flow PCR; Disposable polymer disk; Sandwiched heaters; Spiral microchannel

Indexed keywords

CFD SIMULATIONS; CONSTANT FLOW RATES; CONSTANT TEMPERATURE; CONTINUOUS FLOWS; DEPLOYMENT PROBLEMS; POLYMER DISKS; SANDWICHED HEATERS; SERPENTINE MICROCHANNELS;

COMPUTATIONAL FLUID DYNAMICS; MICROCHANNELS; POLYMERS; SERPENTINE;

POLYMERASE CHAIN REACTION;

EID: 84886575122     PISSN: 09254005     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.snb.2013.09.081     Document Type: Article

References (34)

1. L.J. Kricka, and P. Wilding Microchip PCR Analytical and Bioanalytical Chemistry 377 2003 820 825 (Pubitemid 40877847)
2. P.-A. Auroux, Y. Koc, A. deMello, A. Manz, and P.J.R. Day Miniaturized nucleic acid analysis Lab on a Chip 4 2004 534 546
3. M.G. Roper, C.J. Easley, and J.P. Landers Advances in polymerase chain reaction on microfluidic chips Analytical Chemistry 77 2005 3887 3894
4. C. Zhang, J. Xu, W. Ma, and W. Zheng PCR microfluidic devices for DNA amplification Biotechnology Advances 24 2006 243 284
5. I. Schneega, beta, and J.M. Köhler Flow-through polymerase chain reactions in chip thermocyclers Reviews in Molecular Biotechnology 82 2001 101 121 (Pubitemid 34179609)
6. H. Nakano, K. Matsuda, M. Yohda, T. Nagamune, I. Endo, and T. Yamane High speed polymerase chain reaction in constant flow Bioscience, Biotechnology, and Biochemistry 58 2 1994 349 352 (Pubitemid 2066934)
7. M. Curcio, and J. Roeraade Continuous segmented-flow polymerase chain reaction for high-throughput miniaturized DNA amplification Analytical Chemistry 75 2003 1 7 (Pubitemid 36090071)
8. K.C. Reed Capillary flow PCR: high throughput genetic analysis Australasian Biotechnology 69 1996 280 281 (Pubitemid 27024845)
9. N. Park, S. Kim, and J.H. Hahn Cylindrical compact thermal-cycling device for continuous-flow polymerase chain reaction Analytical Chemistry 75 2003 6029 6033 (Pubitemid 37356488)
10. K.D. Dorfman, M. Chabert, J.-H. Codarbox, G. Rousseau, P. de Cremoux, and J.-L. Viovy Contamination-free continuous flow microfluidic polymerase chain reaction for quantitative and clinical applications Analytical Chemistry 77 2005 3700 3704 (Pubitemid 40799864)
11. N.A. Friedman, and D.R. Meldrum Capillary tube resistive thermal cycling Analytical Chemistry 70 1998 2997 3002
12. J. Chiou, P. Matsudaira, A. Sonin, and D. Ehrlich A closed-cycle capillary polymerase chain reaction machine Analytical Chemistry 73 2001 2018 2021 (Pubitemid 32862408)
13. M.U. Kopp, A.J. de Mello, and A. Manz Chemical amplification: continuous-flow PCR on a chip Science 280 1998 1046 1048 (Pubitemid 28234939)
14. I. Schneega, beta, R. Bräutigam, and J.M. Köhler Miniaturized flow-through PCR with different template types in a silicon chip thermocycler Lab on a Chip 1 2001 42 49
15. K. Sun, A. Yamaguchi, Y. Ishida, S. Mastsuo, and H. Misawa A heater-integrated transparent microchannel chip for continuous-flow PCR Sensors and Actuators B: Chemical 84 2002 283 289 (Pubitemid 34704180)
16. P.J. Obeid, T.K. Christopoulos, H.J. Crabtree, and C.J. Backhouse Microfabricated device for DNA and RNA amplification by continuous-flow polymerase chain reaction and reverse transcription-polymerase chain reaction with cycle number selection Analtical Chemistry 75 2003 288 295 (Pubitemid 36119775)
17. Q.Q. Cao, M.-C. Kim, and C.M. Klapperich Plastic microfluidic chip for continuous-flow polymerase chain reaction: simulations and experiments Biotechnology Journal 6 2011 177 184
18. J. Liu, M. Enzelberger, and S. Quake A nanoliter rotary device for polymerase chain reaction Electrophoresis 23 2002 1531 1536 (Pubitemid 34649584)
19. M. Hashimoto, P.-C. Chen, M.W. Mitchell, D.E. Nikitopoulos, S.A. Soper, and M.C. Murphy Rapid PCR in a continuous flow device Lab on a Chip 4 2004 638 645 (Pubitemid 39657919)
20. W. Wu, K.T.L. Trinh, and N.Y. Lee Hand-held syringe as a portable plastic pump for on-chip continuous-flow PCR: miniaturization of sample injection device Analyst 137 2012 983 990
21. W. Wu, and N.Y. Lee Two-layer microdevice for parallel flow-through PCRs employing plastic syringes for semi-automated sample injection and a single heater for amplification: Toward process simplification and system miniaturization Sensors and Actuators B: Chemical 181 2013 756 765
22. D.M. Grant, M. Blum, A. Demierre, and U.A. Meyer Nucleotide sequence of an intronless gene for a human arylamine N-acetyltransferase related to polymorphic drug acetylation Nucleic Acids Research 17 1989 3978 (Pubitemid 19153383)
23. I. Cascorbi, N. Drakoulis, J. Brockmöller, A. Maurer, K. Sperling, and I. Roots Arylamine N-acetyltransferase (NAT2) mutations and their allelic linkage in unrelated Caucasian individuals: correlation with phenotypic activity American Journal of Human Genetics 57 1995 581 592
24. J.E. Coligan, B.E. Bierer, D.H. Margulies, E.M. Shevach, and W. Strober Short Protocols in Immunology 2005 John Wiley & Sons, Inc. Hoboken, NJ
25. J. Sambrook, and D.W. Russell Molecular Cloning 3rd ed. 2001 Cold Spring Harbor Laboratory Press Cold Spring Harbor, NY
26. N. Chiem, and D.J. Harrison Microchip-based capillary electrophoresis for immunoassay: analysis of monoclonal antibodies and theophylline Analytical Chemistry 69 1997 373 378
27. P.S. Nunes, P.D. Ohlsson, O. Ordeig, and J.P. Kutter Cyclic olefin polymers: emerging materials for lab-on-a-chip applications Microfluidics and Nanofluidics 9 2010 145 161
28. J.M. Li, C. Liu, H.C. Qiao, L.Y. Zhu, G. Chen, and X.D. Dai Hot embossing/bonding of a poly(ethylene terephthalate) (PET) microfluidic chip Journal of Micromechanics and Microengineering 18 2008 1 10
29. W.L. Olbricht, and D.M. Kung The deformation and breakup of liquid drops in low Reynolds number flow through a capillary Physics of Fluids A 4 1992 1347 1354
30. F.M. White Fluid Mechanics 2nd ed. 1986 McGraw-Hill Book Company
31. A. Bejan Convection Heat Transfer 2nd ed. 1995 John Wiley & Sons, Inc.
32. Q. Zhang, W. Wang, H. Zhang, and Y. Wang Temperature analysis of continuous-flow micro-PCR based on FEA Sensors and Actuators B: Chemical 82 2002 75 81 (Pubitemid 34065052)
33. M.W. Mitchell, X. Liu, Y. Bejat, D.E. Nikitopoulos, S.A. Soper, and M.C. Murphy Modeling and validation of a molded polycarbonate continuous flow polymerase chain reaction device Proceedings of SPIE 4982 2003 83 98
34. C.F. Chou, R. Changrani, P. Roberts, D. Sadler, J. Burdon, F. Zenhausern, S. Lin, A. Mulholland, N. Swami, and R. Terbrueggen A miniaturized cyclic PCR device-modelling and experiments Microelectronic Engineering 61 2002 921 925 (Pubitemid 34613465)