Plastic microfluidic chip for continuous-flow polymerase chain reaction: Simulations and experiments

Biotechnology Journal

Volumn 6, Issue 2, 2011, Pages 177-184

  Cao, QingQing ^a   Kim, Min Cheol ^a   Klapperich, Catherine ^a  

^a Boston University   (United States)

Author keywords

Analytical biotechnology; Micro total analysis; Microfluidics; PCR; Thermofluidic modeling

Indexed keywords

ACTUAL CHIPS; ANALYTICAL BIOTECHNOLOGY; ASSAY DEVELOPMENT; COMBINED SIMULATION; CONTINUOUS FLOWS; CONTINUOUS-FLOW; CYCLE TIME; DNA MOLECULES; DNA-TEMPLATE; EXPERIMENTAL DEVELOPMENT; FLUIDIC CHANNELS; GLOBAL HEALTH; MASS PRODUCTION; MICRO TOTAL ANALYSIS; NEW DEVICES; PCR; PCR ASSAY; PCR CHIPS; PLASTIC MICROFLUIDIC CHIPS; RESIDENCE TIME; SMALL SAMPLES; SPATIAL TEMPERATURE VARIATION; STRINGENT REQUIREMENT; TEMPERATURE GRADIENT; TEMPERATURE ZONE; THERMOFLUIDIC MODELING; THERMOPLASTIC MOLDING; THREE CHANNEL;

BIOTECHNOLOGY; COMPUTER SIMULATION; DESIGN; EXPERIMENTS; FLUIDIC DEVICES; MICROFLUIDICS; NUCLEIC ACIDS; POLYMERIZATION; POLYMERS;

POLYMERASE CHAIN REACTION;

DNA; NUCLEIC ACID;

ARTICLE; CONTINUOUS FLOW POLYMERASE CHAIN REACTION; CONTROLLED STUDY; DENATURATION; DNA TEMPLATE; GEL ELECTROPHORESIS; MEAN RESIDENCE TIME; MICROFLUIDIC ANALYSIS; NANOCHIP; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SIMULATION; TEMPERATURE;

BIOTECHNOLOGY; MICROFLUIDICS; POLYMERASE CHAIN REACTION;

EID: 79551646467     PISSN: 18606768     EISSN: 18607314     Source Type: Journal    
DOI: 10.1002/biot.201000100     Document Type: Article

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