PIF-pocket as a target for C. albicans Pkh selective inhibitors

ACS Chemical Biology

Volumn 8, Issue 10, 2013, Pages 2283-2292

  Pastor Flores, Daniel ^a   Schulze, Jörg O ^a   Bahí, Anna ^b   Giacometti, Romina ^c   Ferrer Dalmau, Jofre ^b   Passeron, Susana ^c   Engel, Matthias ^d   Süß, Evelyn ^a   Casamayor, Antonio ^b   Biondi, Ricardo M ^a  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^c UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^d SAARLAND UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

2 [3 (4 CHLOROPHENYL) 1 [2 (4 CHLOROPHENYLTHIO)PHENYL] 3 OXOPROPYLTHIO]ACETIC ACID; ANTIFUNGAL AGENT; FUNGAL PROTEIN; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PKH1 PROTEIN; PKH2 PROTEIN; PROTEIN INHIBITOR; PS 77; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; 2-(3-(4-CHLOROPHENYL)-1-(2-(4-CHLOROPHENYLTHIO)PHENYL)-3-OXOPROPYLTHIO)ACETIC ACID; CHALCONE DERIVATIVE; NEUROTRANSMITTER RECEPTOR; PROLACTIN-INHIBITORY FACTOR RECEPTOR; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; THIOGLYCOLIC ACID DERIVATIVE;

ALLOSTERISM; APOPTOSIS; ARTICLE; CANDIDA ALBICANS; CONTROLLED STUDY; DOUBLE STRANDED DNA BREAK; DRUG MECHANISM; DRUG TARGETING; ENDOCYTOSIS; ENZYME PHOSPHORYLATION; FUNGAL CELL WALL; FUNGAL GENE; FUNGAL STRAIN; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DOMAIN; YEAST CELL; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DELIVERY SYSTEM; DRUG EFFECTS; ENZYME ACTIVATION; ENZYMOLOGY; HUMAN; METABOLISM;

CANDIDA; CANDIDA ALBICANS; SACCHAROMYCETALES;

ALLOSTERIC REGULATION; ANTIFUNGAL AGENTS; BINDING SITES; CANDIDA ALBICANS; CHALCONES; DRUG DELIVERY SYSTEMS; ENZYME ACTIVATION; HUMANS; MODELS, MOLECULAR; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; REACTIVE OXYGEN SPECIES; RECEPTORS, NEUROTRANSMITTER; THIOGLYCOLATES;

EID: 84886481656     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb400452z     Document Type: Article

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