Cell-permeable stapled peptides based on HIV-1 integrase inhibitors derived from HIV-1 Gene products

ACS Chemical Biology

Volumn 8, Issue 10, 2013, Pages 2235-2244

  Nomura, Wataru ^a   Aikawa, Haruo ^a   Ohashi, Nami ^a   Urano, Emiko ^b   Métifiot, Mathieu ^c   Fujino, Masayuki ^b   Maddali, Kasthuraiah ^c   Ozaki, Taro ^a   Nozue, Ami ^a   Narumi, Tetsuo ^a   Hashimoto, Chie ^a   Tanaka, Tomohiro ^a   Pommier, Yves ^c   Yamamoto, Naoki ^d   Komano, Jun A ^b,e   Murakami, Tsutomu ^b   Tamamura, Hirokazu ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^c NATIONAL CANCER INSTITUTE   (United States)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^e OSAKA PREFECTURAL INSTITUTE OF PUBLIC HEALTH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; HYDROCARBON; INTEGRASE INHIBITOR; PEPTIDOMIMETIC AGENT; RUTHENIUM; STAPLED PEPTIDE; UNCLASSIFIED DRUG; VIRUS DNA; VPR PROTEIN; ZIDOVUDINE; INTEGRASE; P31 INTEGRASE PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; PEPTIDE; PROTEIN BINDING;

ALPHA HELIX; AMINO ACID SEQUENCE; ANTIVIRAL ACTIVITY; ARTICLE; BETA SHEET; BIOLOGICAL ACTIVITY; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; DRUG POTENCY; DRUG TARGETING; GENE PRODUCT; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; RING CLOSING METATHESIS; VIRUS CELL INTERACTION; VIRUS REPLICATION; CELL CULTURE; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; CIRCULAR DICHROISM; DRUG DELIVERY SYSTEM; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; IC50; METABOLISM; TUMOR CELL LINE;

HUMAN IMMUNODEFICIENCY VIRUS 1;

AMINO ACID SEQUENCE; CELL LINE, TUMOR; CELL SURVIVAL; CELLS, CULTURED; CIRCULAR DICHROISM; DRUG DELIVERY SYSTEMS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HIV INTEGRASE; HIV INTEGRASE INHIBITORS; HIV-1; HUMANS; INHIBITORY CONCENTRATION 50; MODELS, MOLECULAR; PEPTIDES; PEPTIDOMIMETICS; PROTEIN BINDING;

EID: 84886470520     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb400495h     Document Type: Article

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