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Volumn 110, Issue 43, 2013, Pages 17570-17575

HIF isoforms in the skin differentially regulate systemic arterial pressure

Author keywords

Arginase; HIF alpha; Vascular tone

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; NITRIC OXIDE;

EID: 84886414629     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1306942110     Document Type: Article
Times cited : (58)

References (43)
  • 1
    • 0018816744 scopus 로고
    • Local control of microvascular function: Role in tissue oxygen supply
    • Duling BR, Klitzman B (1980) Local control of microvascular function: Role in tissue oxygen supply. Annu Rev Physiol 42:373-382.
    • (1980) Annu Rev Physiol , vol.42 , pp. 373-382
    • Duling, B.R.1    Klitzman, B.2
  • 2
    • 9344221687 scopus 로고    scopus 로고
    • Noninvasive interrogation of microvasculature for signs of endothelial dysfunction in patients with chronic renal failure
    • Stewart J, et al. (2004) Noninvasive interrogation of microvasculature for signs of endothelial dysfunction in patients with chronic renal failure. Am J Physiol Heart Circ Physiol 287(6):H2687-H2696.
    • (2004) Am J Physiol Heart Circ Physiol , vol.287 , Issue.6
    • Stewart, J.1
  • 3
    • 0033428752 scopus 로고    scopus 로고
    • Lipid-lowering and skin vascular responses in patients with hypercholesterolaemia and peripheral arterial obstructive disease
    • Khan F, Litchfield SJ, Stonebridge PA, Belch JJ (1999) Lipid-lowering and skin vascular responses in patients with hypercholesterolaemia and peripheral arterial obstructive disease. Vasc Med 4(4):233-238.
    • (1999) Vasc Med , vol.4 , Issue.4 , pp. 233-238
    • Khan, F.1    Litchfield, S.J.2    Stonebridge, P.A.3    Belch, J.J.4
  • 4
    • 5344221559 scopus 로고    scopus 로고
    • Skin microcirculation in peripheral arterial obliterative disease
    • RossiM, Carpi A (2004) Skin microcirculation in peripheral arterial obliterative disease. Biomed Pharmacother 58(8):427-431.
    • (2004) Biomed Pharmacother , vol.58 , Issue.8 , pp. 427-431
    • Rossi, M.1    Carpi, A.2
  • 5
    • 30744460616 scopus 로고    scopus 로고
    • Impaired skin blood flow response to environmental heating in chronic heart failure
    • Green DJ, et al. (2006) Impaired skin blood flow response to environmental heating in chronic heart failure. Eur Heart J 27(3):338-343.
    • (2006) Eur Heart J , vol.27 , Issue.3 , pp. 338-343
    • Green, D.J.1
  • 6
    • 34547419604 scopus 로고    scopus 로고
    • Structural alterations of subcutaneous small-resistance arteries may predict major cardiovascular events in patients with hypertension
    • De Ciuceis C, et al. (2007) Structural alterations of subcutaneous small-resistance arteries may predict major cardiovascular events in patients with hypertension. Am J Hypertens 20(8):846-852.
    • (2007) Am J Hypertens , vol.20 , Issue.8 , pp. 846-852
    • De Ciuceis, C.1
  • 7
    • 0030949484 scopus 로고    scopus 로고
    • Impaired microvascular dilatation and capillary rarefaction in young adults with a predisposition to high blood pressure
    • Noon JP, et al. (1997) Impaired microvascular dilatation and capillary rarefaction in young adults with a predisposition to high blood pressure. J Clin Invest 99(8): 1873-1879.
    • (1997) J Clin Invest , vol.99 , Issue.8 , pp. 1873-1879
    • Noon, J.P.1
  • 8
    • 34347227058 scopus 로고    scopus 로고
    • Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1
    • Semenza GL (2007) Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1. Biochem J 405(1):1-9.
    • (2007) Biochem J , vol.405 , Issue.1 , pp. 1-9
    • Semenza, G.L.1
  • 9
    • 33745303045 scopus 로고    scopus 로고
    • Hypoxia signalling in cancer and approaches to enforce tumour regression
    • Pouysségur J, Dayan F, Mazure NM (2006) Hypoxia signalling in cancer and approaches to enforce tumour regression. Nature 441(7092):437-443.
    • (2006) Nature , vol.441 , Issue.7092 , pp. 437-443
    • Pouysségur, J.1    Dayan, F.2    Mazure, N.M.3
  • 10
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza GL (2003) Targeting HIF-1 for cancer therapy. Nat Rev Cancer 3(10):721-732.
    • (2003) Nat Rev Cancer , vol.3 , Issue.10 , pp. 721-732
    • Semenza, G.L.1
  • 11
    • 34047156190 scopus 로고    scopus 로고
    • HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity
    • Gordan JD, Bertout JA, Hu CJ, Diehl JA, Simon MC (2007) HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity. Cancer Cell 11(4): 335-347.
    • (2007) Cancer Cell , vol.11 , Issue.4 , pp. 335-347
    • Gordan, J.D.1    Bertout, J.A.2    Hu, C.J.3    Diehl, J.A.4    Simon, M.C.5
  • 12
    • 41949108403 scopus 로고    scopus 로고
    • Epidermal sensing of oxygen is essential for systemic hypoxic response
    • Boutin AT, et al. (2008) Epidermal sensing of oxygen is essential for systemic hypoxic response. Cell 133(2):223-234.
    • (2008) Cell , vol.133 , Issue.2 , pp. 223-234
    • Boutin, A.T.1
  • 13
    • 37549032776 scopus 로고    scopus 로고
    • The interplay between MYC and HIF in cancer
    • Dang CV, Kim JW, Gao P, Yustein J (2008) The interplay between MYC and HIF in cancer. Nat Rev Cancer 8(1):51-56.
    • (2008) Nat Rev Cancer , vol.8 , Issue.1 , pp. 51-56
    • Dang, C.V.1    Kim, J.W.2    Gao, P.3    Yustein, J.4
  • 14
    • 0033954247 scopus 로고    scopus 로고
    • Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha
    • Ravi R, et al. (2000) Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha. Genes Dev 14(1):34-44.
    • (2000) Genes Dev , vol.14 , Issue.1 , pp. 34-44
    • Ravi, R.1
  • 15
    • 70149106164 scopus 로고    scopus 로고
    • HIF2alpha inhibition promotes p53 pathway activity, tumor cell death, and radiation responses
    • Bertout JA, et al. (2009) HIF2alpha inhibition promotes p53 pathway activity, tumor cell death, and radiation responses. Proc Natl Acad Sci USA 106(34):14391-14396.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.34 , pp. 14391-14396
    • Bertout, J.A.1
  • 16
    • 71549151624 scopus 로고    scopus 로고
    • Suppression of hypoxia-inducible factor 2alpha restores p53 activity via Hdm2 and reverses chemoresistance of renal carcinoma cells
    • Roberts AM, et al. (2009) Suppression of hypoxia-inducible factor 2alpha restores p53 activity via Hdm2 and reverses chemoresistance of renal carcinoma cells. Cancer Res 69(23):9056-9064.
    • (2009) Cancer Res , vol.69 , Issue.23 , pp. 9056-9064
    • Roberts, A.M.1
  • 17
    • 10044276783 scopus 로고    scopus 로고
    • Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex
    • Brugarolas J, et al. (2004) Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex. Genes Dev 18(23):2893-2904.
    • (2004) Genes Dev , vol.18 , Issue.23 , pp. 2893-2904
    • Brugarolas, J.1
  • 18
    • 0037154262 scopus 로고    scopus 로고
    • Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1 alpha
    • Kline DD, Peng YJ, Manalo DJ, Semenza GL, Prabhakar NR (2002) Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1 alpha. Proc Natl Acad Sci USA 99(2):821-826.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.2 , pp. 821-826
    • Kline, D.D.1    Peng, Y.J.2    Manalo, D.J.3    Semenza, G.L.4    Prabhakar, N.R.5
  • 19
    • 79952609061 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension
    • Peng YJ, et al. (2011) Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension. Proc Natl Acad Sci USA 108(7):3065-3070.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.7 , pp. 3065-3070
    • Peng, Y.J.1
  • 20
    • 59049086571 scopus 로고    scopus 로고
    • Intermittent hypoxia degrades HIF-2alpha via calpains resulting in oxidative stress: Implications for recurrent apnea-induced morbidities
    • Nanduri J, et al. (2009) Intermittent hypoxia degrades HIF-2alpha via calpains resulting in oxidative stress: Implications for recurrent apnea-induced morbidities. Proc Natl Acad Sci USA 106(4):1199-1204.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.4 , pp. 1199-1204
    • Nanduri, J.1
  • 21
    • 84877347155 scopus 로고    scopus 로고
    • Mutual antagonism between hypoxia-inducible factors 1α and 2α regulates oxygen sensing and cardio-respiratory homeostasis
    • Yuan G, et al. (2013) Mutual antagonism between hypoxia-inducible factors 1α and 2α regulates oxygen sensing and cardio-respiratory homeostasis. Proc Natl Acad Sci USA 110(19):E1788-E1796.
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.19
    • Yuan, G.1
  • 22
    • 77649177217 scopus 로고    scopus 로고
    • Differential activation and antagonistic function of HIF-alpha isoforms in macrophages are essential for NO homeostasis
    • Takeda N, et al. (2010) Differential activation and antagonistic function of HIF-alpha isoforms in macrophages are essential for NO homeostasis. Genes Dev 24(5):491-501.
    • (2010) Genes Dev , vol.24 , Issue.5 , pp. 491-501
    • Takeda, N.1
  • 23
    • 77954340266 scopus 로고    scopus 로고
    • Endothelium-dependent control of vascular tone during early postnatal and juvenile growth
    • Boegehold MA (2010) Endothelium-dependent control of vascular tone during early postnatal and juvenile growth. Microcirculation 17(5):394-406.
    • (2010) Microcirculation , vol.17 , Issue.5 , pp. 394-406
    • Boegehold, M.A.1
  • 24
    • 0031939735 scopus 로고    scopus 로고
    • Evolution of chronic nitric oxide inhibition hypertension: Relationship to renal function
    • Qiu C, Muchant D, Beierwaltes WH, Racusen L, Baylis C (1998) Evolution of chronic nitric oxide inhibition hypertension: Relationship to renal function. Hypertension 31(1):21-26.
    • (1998) Hypertension , vol.31 , Issue.1 , pp. 21-26
    • Qiu, C.1    Muchant, D.2    Beierwaltes, W.H.3    Racusen, L.4    Baylis, C.5
  • 25
    • 83455209997 scopus 로고    scopus 로고
    • Role of blood cell-associated angiotensin II type 1 receptors in the cerebral microvascular response to ischemic stroke during angiotensin-induced hypertension
    • Nagai M, et al. (2011) Role of blood cell-associated angiotensin II type 1 receptors in the cerebral microvascular response to ischemic stroke during angiotensin-induced hypertension. Exp Transl Stroke Med 3:15.
    • (2011) Exp Transl Stroke Med , vol.3 , pp. 15
    • Nagai, M.1
  • 26
    • 0032102990 scopus 로고    scopus 로고
    • Alternative metabolic states in murine macrophages reflected by the nitric oxide synthase/arginase balance: Competitive regulation by CD4+ T cells correlates with Th1/Th2 phenotype
    • Munder M, Eichmann K, Modolell M (1998) Alternative metabolic states in murine macrophages reflected by the nitric oxide synthase/arginase balance: Competitive regulation by CD4+ T cells correlates with Th1/Th2 phenotype. J Immunol 160(11): 5347-5354.
    • (1998) J Immunol , vol.160 , Issue.11 , pp. 5347-5354
    • Munder, M.1    Eichmann, K.2    Modolell, M.3
  • 27
    • 0028786601 scopus 로고
    • A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter
    • Melillo G, et al. (1995) A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter. J Exp Med 182(6):1683-1693.
    • (1995) J Exp Med , vol.182 , Issue.6 , pp. 1683-1693
    • Melillo, G.1
  • 28
    • 1842835747 scopus 로고    scopus 로고
    • Effects of mode of exercise recovery on thermoregulatory and cardiovascular responses
    • Carter R, 3rd, Wilson TE, Watenpaugh DE, Smith ML, Crandall CG (2002) Effects of mode of exercise recovery on thermoregulatory and cardiovascular responses. J Appl Physiol 93(6):1918-1924.
    • (2002) J Appl Physiol , vol.93 , Issue.6 , pp. 1918-1924
    • Carter III, R.1    Wilson, T.E.2    Watenpaugh, D.E.3    Smith, M.L.4    Crandall, C.G.5
  • 29
    • 77955475952 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide gene expression differences in onset and maintenance phases of genetic hypertension
    • Marques FZ, Campain AE, Yang YH, Morris BJ (2010) Meta-analysis of genome-wide gene expression differences in onset and maintenance phases of genetic hypertension. Hypertension 56(2):319-324.
    • (2010) Hypertension , vol.56 , Issue.2 , pp. 319-324
    • Marques, F.Z.1    Campain, A.E.2    Yang, Y.H.3    Morris, B.J.4
  • 30
    • 0346156049 scopus 로고    scopus 로고
    • Cosegregation analysis of natriuretic peptide genes and blood pressure in the spontaneously hypertensive rat
    • Ye P, West MJ (2003) Cosegregation analysis of natriuretic peptide genes and blood pressure in the spontaneously hypertensive rat. Clin Exp Pharmacol Physiol 30(12): 930-936.
    • (2003) Clin Exp Pharmacol Physiol , vol.30 , Issue.12 , pp. 930-936
    • Ye, P.1    West, M.J.2
  • 31
    • 78149255616 scopus 로고    scopus 로고
    • Mechanisms underlying the cerebral microvascular responses to angiotensin II-induced hypertension
    • Vital SA, Terao S, Nagai M, Granger DN (2010) Mechanisms underlying the cerebral microvascular responses to angiotensin II-induced hypertension. Microcirculation 17(8):641-649.
    • (2010) Microcirculation , vol.17 , Issue.8 , pp. 641-649
    • Vital, S.A.1    Terao, S.2    Nagai, M.3    Granger, D.N.4
  • 32
    • 24144469144 scopus 로고    scopus 로고
    • Angiotensin II regulates vascular endothelial growth factor via hypoxia-inducible factor-1alpha induction and redox mechanisms in the kidney
    • Sanchez-Lopez E, et al. (2005) Angiotensin II regulates vascular endothelial growth factor via hypoxia-inducible factor-1alpha induction and redox mechanisms in the kidney. Antioxidants & redox signaling 7(9-10):1275-1284.
    • (2005) Antioxidants & Redox Signaling , vol.7 , Issue.9-10 , pp. 1275-1284
    • Sanchez-Lopez, E.1
  • 33
    • 33745825575 scopus 로고    scopus 로고
    • Characterization of NO and cytokine production in immuneactivated microglia and peritoneal macrophages derived from a mouse model expressing the human NOS2 gene on a mouse NOS2 knockout background
    • Vitek MP, et al. (2006) Characterization of NO and cytokine production in immuneactivated microglia and peritoneal macrophages derived from a mouse model expressing the human NOS2 gene on a mouse NOS2 knockout background. Antioxidants & redox signaling 8(5-6):893-901.
    • (2006) Antioxidants & Redox Signaling , vol.8 , Issue.5-6 , pp. 893-901
    • Vitek, M.P.1
  • 34
    • 70449725149 scopus 로고    scopus 로고
    • Pressure-induced vascular oxidative stress is mediated through activation of integrin-linked kinase 1/betaPIX/Rac-1 pathway
    • Vecchione C, et al. (2009) Pressure-induced vascular oxidative stress is mediated through activation of integrin-linked kinase 1/betaPIX/Rac-1 pathway. Hypertension 54(5):1028-1034.
    • (2009) Hypertension , vol.54 , Issue.5 , pp. 1028-1034
    • Vecchione, C.1
  • 35
    • 0028945027 scopus 로고
    • Renal effects of acute amino acid infusion in hypertension induced by chronic nitric oxide blockade
    • Qiu C, Engels K, Samsell L, Baylis C (1995) Renal effects of acute amino acid infusion in hypertension induced by chronic nitric oxide blockade. Hypertension 25(1):61-66.
    • (1995) Hypertension , vol.25 , Issue.1 , pp. 61-66
    • Qiu, C.1    Engels, K.2    Samsell, L.3    Baylis, C.4
  • 36
    • 20944433770 scopus 로고    scopus 로고
    • Protection from angiotensin II-mediated vasculotoxic and hypertensive response in mice lacking PI3Kgamma
    • Vecchione C, et al. (2005) Protection from angiotensin II-mediated vasculotoxic and hypertensive response in mice lacking PI3Kgamma. J Exp Med 201(8):1217-1228.
    • (2005) J Exp Med , vol.201 , Issue.8 , pp. 1217-1228
    • Vecchione, C.1
  • 37
    • 70350566223 scopus 로고    scopus 로고
    • Loss of arterial and renal nitric oxide bioavailability in hypertensive rats with diabetes: Effect of beta-blockers
    • Mason RP, et al. (2009) Loss of arterial and renal nitric oxide bioavailability in hypertensive rats with diabetes: Effect of beta-blockers. Am J Hypertens 22(11):1160-1166.
    • (2009) Am J Hypertens , vol.22 , Issue.11 , pp. 1160-1166
    • Mason, R.P.1
  • 39
    • 80054763491 scopus 로고    scopus 로고
    • Association between serum nitric oxide metabolites and hypertension in a general population
    • Ghasemi A, Zahediasl S, Syedmoradi L, Azizi F (2011) Association between serum nitric oxide metabolites and hypertension in a general population. Int Angiol 30(4):380-387.
    • (2011) Int Angiol , vol.30 , Issue.4 , pp. 380-387
    • Ghasemi, A.1    Zahediasl, S.2    Syedmoradi, L.3    Azizi, F.4
  • 40
    • 82555170266 scopus 로고    scopus 로고
    • Effect of oral L-arginine supplementation on blood pressure: A meta-analysis of randomized, double-blind, placebo-controlled trials
    • Dong JY, et al. (2011) Effect of oral L-arginine supplementation on blood pressure: A meta-analysis of randomized, double-blind, placebo-controlled trials. Am Heart J 162(6):959-965.
    • (2011) Am Heart J , vol.162 , Issue.6 , pp. 959-965
    • Dong, J.Y.1
  • 41
    • 4744362273 scopus 로고    scopus 로고
    • L-arginine and hypertension
    • discussion 2818S-2819S
    • Gokce N (2004) L-arginine and hypertension. J Nutr 134(10 Suppl):2807S-2811S; discussion 2818S-2819S.
    • (2004) J Nutr , vol.134 , Issue.10 SUPPL.
    • Gokce, N.1
  • 42
    • 0003633755 scopus 로고
    • Committee on Care and Use of Laboratory Animals (Natl Inst Health, Bethesda), DHHS Publ No (NIH)
    • Committee on Care and Use of Laboratory Animals (1985) Guide for the Care and Use of Laboratory Animals (Natl Inst Health, Bethesda), DHHS Publ No (NIH) 85-23.
    • (1985) Guide for the Care and Use of Laboratory Animals , pp. 85-23
  • 43
    • 56549094724 scopus 로고    scopus 로고
    • Validation of volume-pressure recording tail-cuff blood pressure measurements
    • Feng M, et al. (2008) Validation of volume-pressure recording tail-cuff blood pressure measurements. Am J Hypertens 21(12):1288-1291.
    • (2008) Am J Hypertens , vol.21 , Issue.12 , pp. 1288-1291
    • Feng, M.1


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