Protective effects of vitamin E and selenium against dimethoate-induced cardiotoxicity in vivo: Biochemical and histological studies

Environmental Toxicology

Volumn 28, Issue 11, 2013, Pages 630-643

  Amara, Ibtissem Ben ^a   Soudani, Nejla ^a   Hakim, Ahmed ^b   Troudi, Afef ^a   Zeghal, Khaled Mounir ^b   Boudawara, Tahia ^c   Zeghal, Najiba ^a  

^a université de Sfax   (Tunisia)

^b UNIVERSITY OF SFAX   (Tunisia)

^c HABIB BOURGUIBA HOSPITAL   (Tunisia)

Author keywords

Antioxidant and lipid profiles; Cardiotoxicity; Dimethoate; Histopathological studies; Rats; Selenium; Vitamin E

Indexed keywords

CARDIOTOXICITY; DIMETHOATE; HISTOPATHOLOGICAL STUDIES; LIPID PROFILE; VITAMIN-E;

ANTIOXIDANTS; CHOLESTEROL; FREE RADICALS; LIPOPROTEINS; NUTRITION; OXYGEN; PEPTIDES; RATING; RATS;

SELENIUM;

ACETYLCHOLINESTERASE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ALPHA TOCOPHEROL; ASCORBIC ACID; CATALASE; CHOLESTEROL; DIMETHOATE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MALONALDEHYDE; SELENIUM; SUPEROXIDE DISMUTASE; THIOL; TRIACYLGLYCEROL;

ANTIOXIDANT; BIOCHEMISTRY; ENZYME ACTIVITY; ESTER; HISTOLOGY; HISTOPATHOLOGY; OXIDATION; POLLUTION EXPOSURE; PROTEIN; RODENT; SELENIUM; VITAMIN; XENOBIOTICS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOTOXICITY; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HEART PROTECTION; HISTOLOGY; HISTOPATHOLOGY; IN VIVO STUDY; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; TREATMENT OUTCOME; TRIACYLGLYCEROL BLOOD LEVEL;

ANTIOXIDANT AND LIPID PROFILES; CARDIOTOXICITY; DIMETHOATE; HISTOPATHOLOGICAL STUDIES; RATS; SELENIUM; VITAMIN E;

ACETYLCHOLINESTERASE; ADENOSINE TRIPHOSPHATASES; ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; CHOLESTEROL; DIMETHOATE; FEMALE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; LIPID PEROXIDATION; MALONDIALDEHYDE; MYOCARDIUM; OXIDATION-REDUCTION; OXIDATIVE STRESS; PESTICIDES; PROTEIN CARBONYLATION; RATS; RATS, WISTAR; SODIUM SELENITE; SUPEROXIDE DISMUTASE; TRIGLYCERIDES; VITAMIN E;

RATTUS; RATTUS NORVEGICUS;

EID: 84886305283     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.20759     Document Type: Article

References (99)

1. Abbas R, Hayton WL.1997.A physiologically based pharmacokinetic and pharmacodynamic model for paraoxon in rainbow trout.Toxicol Appl Pharmacol145:192-201.
2. Aebi H.1984.Catalase in vitro.Method Enzymol105:121-126.
3. Aggarwal M, Naraharisetti SB, Sarkar SN, Rao GS, Degen GH, Malik JK.2009.Effects of subchronic coexposure to arsenic and endosulfan on the erythrocytes of broiler chickens: A biochemical study.Arch Environ Contam Toxicol56:139-148.
4. Al-Haj M, Nasser A, Anis A.2005.Survey of pesticides used in Qat cultivation in Dhale and Yafe and their adverse effects.J Nat Appl Sci9:103-110.
5. Alissa EM, Bahijri SM, Ferns GA.2003.The controversy surrounding selenium and cardiovascular disease: A review of the evidence.Med Sci Monit9:RA9-RA18.
6. Andersen HM, Regueira HT, Leighton F.2006.Oxidative stress in critically ill patients.Rev Med Chil134:649-656.
7. Aslam F, Khan A, Khan MZ, Sharaf S, Gul ST, Saleemi MK.2009.Toxico-pathological changes induced by cypermethrin in broiler chicks: Their attenuation with vitamin E and selenium.Exp Toxicol Pathol62:441-450.
8. Attia AM, Nasr H.2009.Dimethoate-induced changes in biochemical parameters of experimental rat serum its neutralization by black seed (Nigella Sativa L.).Oil Slovak J Anim Sci42:87-94.
9. Beauchamp C, Fridovich I.1971.Superoxide dismutase: Improved assays and an assay applicable to acryl amide gels.Anal Biochem44:276-287.
10. Ben Amara I, Troudi A, Garoui E, Hakim A, Zeghal KM, Zeghal N.2010.Protective effects of selenium on methimazole nephrotoxicity in adult rats and their offspring.Exp Toxicol Pathol doi:10.1016/j.etp.2010.04.007.
11. Bendich A, Machlin LJ, Scandurra A, Burton GW, Wayner DDM.1986.The antioxidant role of vitamin C. Adv.Free Radic Biol Med2:419-444.
12. Brownlee M.2001.Biochemistry and molecular cell biology of diabetic complications.Nature414:813-820.
13. Bursell SE, King GL.1992.Can protein kinase C inhibition and vitamin E prevent the development of diabetic vascular complications?Diabetes Res Clin Pract45:169-182.
14. Burstein M, Scholnick HR, Morfin R.1970.Rapid method for the isolation of lipoproteins from human serum by precipitation with polyanions.J Lipid Res11:583-595.
15. Cai L, Wang Y, Zhou G, Chen T, Song Y, Li X, Kang YJ.2006.Attenuation by metallothionein of early cardiac cell death via suppression of mitochondrial oxidative stress results in a prevention of diabetic cardiomyopathy.J Am Coll Card48:1688-1697.
16. Chappuis P, Poupon J.1991.Le rôle de sélénium dans la défense du stress oxydatif.Cah Nutr Diet26:295-297.
17. Chen Z, Young TE, Ling J, Chang SC, Gallie DR.2003.Increasing vitamin C content of plants through enhanced ascorbate recycling.Proc Natl Acad Sci USA100:3525-3530.
18. Chow CK.1990.Effect of dietary vitamin E and selenium on rats: pyruvate kinase, glutathione peroxidase and oxidative damage.Nutr Res10:183-194.
19. Council of European Communities.1986.Council instructions about the protection of living animals used in scientific investigations.Official J Eur Communities (JO 86/609/CEE) L358:1-18.
20. Crespo AMV, Lanca MJ, Vasconcelos S, Andrade V, Rodrigues H, Santos MC.1995.Effect of selenium supplementation on some blood biochemical parameters in male rats.Biol Trace Element Res47:343-347.
21. De-Bleecker J, Van-Den-Neucker K, Colradyn F.1993.Intermediate syndrome in organophosphorus poisoning: A prospective study.Crit Care Med21:1706-1711.
22. Delwing-de Lima D, Wollinger LF, Casagrande AC, Delwing F, Da Cruz JG, Wyse AT, Delwing-Dal Magro D.2010.Guanidino compounds inhibit acetylcholinesterase and butyrylcholinesterase activities: Effect neuroprotector of vitamins E plus C.Int J Dev Neurosc28:465-473.
23. Dongren Y, Taol L, Fengsheng H.1999.Electrophysiological studies in rats of acute dimethoate poisoning.Toxico Lett107:1-3.
24. Draper HH, Hadley M.1990.Malondialdehyde determination as index of lipid peroxidation.Methods Enzymol186:421-431.
25. Ecobichon DJ.1991 Toxic effects of pesticides. In: Amdur MO, Doull J, Klaassen CD, editors.Cassarett and Doull's Toxicology, 4th ed.New York:Pergamon. pp.565-622.
26. Ellman GL.1959.Tissue sulfhydryl groups.Arch Biochem Biophys82:70-77.
27. Ellman GL, Courtney KD, Andres V, Featherstone R.1961.A new and rapid colorimetric determination of acetyl cholinesterase activity.Biochem Pharmacol7:88-95.
28. Faine LA, Rodrigues HG, Galhardi CM, Ebaid GMX, Diniz YS, Fernandes AAH, Novelli ELB.2006.Butyl hydroxytoluene (BHT)-induced oxidative stress: Effects on serum lipids and cardiac energy metabolism in rats.Exp Toxicol Pathol57:221-226.
29. Ferda DEA, Ugur S.2010.The effect of Dichlorvos on acetylcholinesterase activity in some tissues in rats.Acta Vet60:123-131.
30. Flohe L, Gunzler WA.1984.Assays of glutathione peroxidase.Method Enzymol105:114-121.
31. Fogg P, Boxall AB, Walker A, Jukes AA.2003.Pesticide degradation in a biobed composting substrate.Pest Manag Sci59:527-537.
32. Fossati P, Prencipe L.1982.Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide.Clin Chem28:2077-2080.
33. Friedewald WT.1972.Estimation of concentration of low-density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge.Clin Chem18:499-502.
34. Gallan PM, Carrascosa A, Gussinye M, Dominguez C.2003.Biomarkers of diabetes-associated oxidative stress and antioxidant status in young diabetic patients with or without subclinical complication.Free Radic Biol Med34:1563-1574.
35. Gan L, Liu Q, Xu HB, Zhu YS, Yang XL.2002.Effects of selenium overexposure on glutathione peroxidase and thioredoxin reductase gene expressions and activities.Biol Trace Elem Res89:165-175.
36. Gregus Z, Klaassen CD.2001. Mechanism of toxicity. In: Klaassen CD, editor.Casarett and Doull's Toxicology: The Basic Science of Poisons, 6th ed.McGraw-Hill:New York. pp35-81.
37. Halliwell B, Gutteridge JMC.2001. Oxidative stress: Adaptation, damage, repair and death. In: Halliwell B, Gutteridge J.M.C. (eds), Free Radicals in Biology and Medicine. 3rd Ed. Oxford, UK:Oxford University Press Oxford, . pp246-350.
38. Hayes WJ.1982.Pesticides Studied in Man.Baltimore, MD:Williams and Wilkins.
39. Hayes W, Laws E.1990.Handbook of Pesticide Toxicology, Classes of Pesticides.Academic Press:NY. p425.
40. Hong JH, Kim MJ, Park MR, Kwag OG, Lee IS, Byun BH, Lee SC, Lee KB, Rhee SJ.2004.Effects of vitamin E on oxidative stress and membrane fluidity in brain streptozotocin induced diabetic rats.Clin Chim Acta340:107-115.
41. Hsiao CT, Yang CC, Deng JF, Bullard MJ, Liaw SJ.1996.Acute pancreatitis following organophosphate intoxication.J Toxicol Clin Toxicol34:343-347.
42. Institoris L, Siroki O, Desi I, Undeger U.1999.Immunotoxicological examination of repeated dose combined exposure by dimethoate and two heavy metals in rats.Hum Exp Toxicol18:88-94.
43. Jacques-Silva MC, Nogueira CW, Broch LC.2001.Diphenyl diselenide and ascorbic acid changes deposition of selenium and ascorbic acid in liver and brain of mice.Pharm Toxicol88:119-25.
44. John S, Kale M, Rathore N, Bhatnagar D.2001.Protective effect of vitamin E in dimethoate and malathion induced oxidative stress in rat erythrocytes.J Nutr Biochem12:500-504.
45. Jollow DJ, Mitchell JR, Zampaglione N, Gillete JR.1974.Bromobenzene induced liver necrosis: Protective role of glutathione and evidence for 3, 4-bromobenzeneoxide as the hepatotoxic intermediate.Pharmacology11:151-169.
46. Kamath V, Rajini PS.2007.Altered glucose homeostasis and oxidative impairment in pancreas of rats subjected to dimethoate intoxication.Toxicology231:137-146.
47. Kang YJ.2001.Molecular and cellular mechanisms of cardiotoxicity.Environ Health Perspect109:27-34.
48. Katsanidis E, Addis PB.1999.Novel HPLC analysis of tocopherols, tocotrienols, and cholesterol in tissue.Free Radic Biol Med27:1137-1140.
49. Kawamoto EM, Munhoz CD, Glezer I, Bahia VS, Caramelli P, Nitrini R, Gorjao R, Curi R, Scavone C, Marcourakis T.2005.Oxidative state in platelets and erythrocytes in aging and Alzheimer's disease.Neurobiol Aging26:857-864.
50. Kayali R, Cakatay U, Akcay T, Altug T.2006.Effect of alpha-lipoic acid supplementation on markers of protein oxidation in post-mitotic tissues of ageing rat.Cell Biochem Funct24:79-85.
51. Lewin TM, Coleman RA.2003.Regulation of myocardial triacylglycerol synthesis and metabolism.Biochim Biophys Acta1694:63-75.
52. Li X, Hill KE, Burk RF, May JM.2001.Selenium spares ascorbate and K-tocopherol incultured liver cell lines under oxidant stress.FEBS Lett508:489-492.
53. Li S, Li X, Rozanski GJ.2003.Regulation of glutathione in cardiac myocytes.J Mol Cell Card35:1145-1152.
54. Lowry OH, Rosebrugh NJ, Farr AL, Randall RJ.1951.Protein measuremernt with the Folin phenol reagent.J Biol Chem193:265-275.
55. Lukaszewicz-Hussain A.2008.Subchronic intoxication with chlorfenvinphos, an organophosphate insecticide, affects rat brain antioxidative enzymes and glutathione level.Food Chem Toxicol46:82-86.
56. Lundebyel AK, Curtis TM, Braven J, Depledge MH.1997.Effects of the organophosphorous pesticide, dimethoate, on cardiac and acetylcholinesterase (AChE) activity in the shore crab Curcinus maenas.Aquatic Toxicol40:23-36.
57. Mahjoubi-Samet A, Fetoui H, Zeghal N.2008.Nephrotoxicity induced by dimethoate in adult rats and their suckling pups.Pesticide Biochem Physiol91:96-103.
58. Marrs TC.1993.Organophosphate poisoning.Pharmacol Therapeutics58:51-66.
59. McDonough KH.1999.The role of alcohol in the oxidant antioxidant balance in heart.Front Biosci4:601-606.
60. Meydani M.1995.Vitamin E.Lancet345:170-175.
61. 2+-ATPase activity, and EEG records in pentylentetrazol-induced seizures in rats.J Membr Biol225:39-49.
62. Ognjanovic BI, Markovic SD, Pavlovic SZ, Zikic RV, Stajn AS, Saicic ZS.2008.Effect of chronic cadmium exposure on antioxidant defense system in some tissues of rats: protective effect of selenium.Physiol Res57:403-411.
63. Ogutcu A, Uzunhisarcikli M, Kalender S, Durak D, Bayrakdar F, Kalender Y.2006.The effect of organophosphate insecticide diazinon on malaondialdehyde levels and myocardial cells in rat heart tissue and protective role of Vitamin E.Pest Biochem Physiol86:93-98.
64. 3+)-induced rainbow trout.Ecotoxicol Environ Saf71:71-75.
65. Othman AI, El Missiry MA.1998.Role of selenium against lead toxicity in male rats.J Biochem Mol Toxicol12:345-349.
66. Pascoe G, Olafsdottir K, Read DJ.1987.Vitamin E protection against chemical induced cell injury. I. Maintenance of cellular protein thiols as a cytoprotective mechanism.Arch Biochem Biophys256:150-158.
67. Poet TS, Kousba AA, Dennison SL, Timchalk C.2004.Physiologically based pharmacokinetic/pharmacodynamic model for the organophosphorus pesticide diazinon.Neurotoxicology25:1013-1030.
68. Pour ZM, Zal F, Monabati A, Vessal MO.2008.Protective effects of a combination of quercetin and vitamin E against cyclosporine A-induced oxidative stress and hepatotoxicity in rats.Hepatol Res38:385-392.
69. Prakasam A, Sethupathy S, Lalitha S.2001.Plasma and RBCs antioxidant status in occupational male pesticide sprayers.Clin Chim Acta310:107-112.
70. Priscilla D, Hansi Prince P.2009.Stanely Mainzen. Cardioprotective effect of gallic acid on cardiac troponin-T, cardiac marker enzymes, lipid peroxidation products and antioxidants in experimentally induced myocardial infarction in Wistar rats.Chem Biol Interact179:118-124.
71. Punithavathi VR, Prince SM.2009.Combined effects of quercetin and tocopherol on lipids and glycoprotein components in isoproterenol induced myocardial infarcted Wistar rats.Chem Biol Interact181:322-327.
72. Reznick AZ, Packer L.1994.Oxidative Damage to Proteins: Spectrophotometric Method for Carbonyl. Method Enzymol.Academic Press:New York. p357.
73. Richmond W.1973.Preparation and properties of a cholesterol oxidase from Nocardia sp. And its application to the enzymatic assay of total cholesterol in serum.Clin Chem19:1350-1356.
74. Sabbah HN, Stanley CW.2003.Partial fatty acid oxidation inhibitors: A potentially new class of drugs for heart failure.Eur J Heart Fail4:3-6.
75. Saito Y, Takahashi K.2002.Characterization of selenoprotein P as a selenium supply protein.Eur J Biochem269:5746-5751.
76. Sayim F.2007.Dimethoate-induced biochemical and histopathological changes in the liver of rats.Exp Toxicol Pathol59:237-243.
77. Schwenke DC, Behr SR.1998.Vitamin E combined with selenium inhibits atherosclerosis in hypercholesterolemic rabbits independently of effects on plasma cholesterol concentrations.Circ Res83:366-377.
78. Sengupta T, Chattopadhyay D, Ghosh N, Das M, Chatterjee GC.1990.Effect of chromium administration on glutathione cycle of rat intestinal epithelial cells.Ind J Exp Biol28:1132-1135.
79. Sharma Y, Bashir S, Irshad M, Gupta SD, Dogra TD.2005a.Effects of acute dimethoate administration on antioxidant status of liver and brain of experimental rats.Toxicology206:49-57.
80. Sharma Y, Bashir S, Irshad M, Nagc TC, Dogra TD.2005b.Dimethoate-induced effects on antioxidant status of liver and brain of rats following subchronic exposure.Toxicology215:173-181.
81. Shirpoor A, Salami S, Khadem-Ansari MH, Ilkhanizadeh B, Pakdel FG, Khademvatani K.2009.Cardioprotective effect of vitamin E: rescues of diabetes-induced cardiac malfunction, oxidative stress, and apoptosis in rat.J Diabetes Complications23:310-316.
82. Sohal RS, Weindruch R.1996.Oxidative stress, caloric restriction and aging.Science273:59-63.
83. Soudani N, Troudi A, Bouaziz H, Ben Amara I, Boudawara T, Zeghal N.2010.Cardioprotective effects of selenium on chromium (VI)-induced toxicity in female rats.Ecotoxicol Environ Saf74:513-520.
84. Sridevi N, Venkataraman P, Senthilkumar K, Krishnamoorthy G, Arunakaran J.2007.Oxidative stress modulates membrane bound ATPases in brain regions of PCB (Aroclor 1254) exposed rats: Protective role of α-tocopherol.Biomed Pharm61:435-440.
85. Steiner M.1991.Influence of vitamin E on platelet functions in humans.J Am Coll Nutr10:466-473.
86. Stenersen J.2004.Chemical Pesticides: Mode of Action and Toxicology.C.R.C. Press:Baca Ration, Florida.
87. Stohs SJ, Bagchi D.1995.Oxidative mechanisms in the toxicity of metal ions.Free Radic Biol Med18:321-336.
88. Swynghedauw B.1999.Molecular mechanisms of myocardial remodeling.Physiological Rev79:215-262.
89. Talas ZS, Ozdemir I, Yilmaz I, Gok Y, Veorun I.2008.The investigation of the antioxidative properties of the novel synthetic organoselenium compounds in some rat tissues.Exp Biol Med233:575-579.
90. Tuduri L, Harner T, Blanchard P, Li Y-F, Poissant L, Waite DT, Murphy C, Belzer W.2006.A review of currently used pesticides (CUPs) in Canadian air and precipitation. II. Regional information and perspectives.Atmos Environ40:1563-1578.
91. Upaganlawar A, Balaraman R.2010.Effect of vitamin E and green tea on hemodynamic, electrocardiographic and some biochemical alterations in experimentally induced myocardial infarction in rats.Europ J Integrat Med2:135-141.
92. Verlangieri AJ, Bush MJ.1992.Effects of d-alpha-tocopherol supplementation on experimentally induced primate atherosclerosis.J Am Coll Nutr11:131-138.
93. Warren S, Patel S, Kapron CM.2000.The effect of vitamin E exposure on cadmium toxicity in mouse embryo cells.Toxicology142:119-126.
94. Watson WA, Litovitz TL, Rodgers GCJr, Klein-Schwartz W, Youniss J, Rose SR, Borys D, May ME.2003.2002 annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System.Am J Emerg Med21:353-421.
95. WHO.2009. The WHP Recommended Classification of Pesticides by Hazard and Guidelines to Classification. World Health Organization Programme on Chemical Safety, Geneva.
96. WHO/IPCS.1996. Principles and methods for assessing direct immunotoxicity associated with exposure to chemicals. Environmental Health Criteria vol. 180. WHO, Geneva, 110-112.
97. Wojcicki J, Rozewicka L, Barcew-Wiszniewska B, Samochowiec L, Juzwiak S, Kadlubowska D, Tustanowski S, Juzyszyn Z.1991.Effect of selenium and vitamin E on the development of experimental atherosclerosis in rabbits.Atherosclerosis87:9-16.
98. Wu ML, Deng JF, Tsai WJ, Ger J, Wong SS, Li HP.2001.Food poisoning due to methamidophos-contaminated vegetables.J Toxicol Clin Toxicol39:333-336.
99. Yogeeta SK, Balaji HBR, Gnanapragasam A, Senthilkumar S, Subhashini R, Devaki T.2006.Attenuation of abnormalities in the lipid metabolism during experimental myocardial infarction induced by isoproterenol in rats-Beneficial effect of ferulic acid and ascorbic acid.Basic Clin Pharmacol Toxicol98:467-472.