Butyl hydroxytoluene (BHT)-induced oxidative stress: Effects on serum lipids and cardiac energy metabolism in rats

Experimental and Toxicologic Pathology

Volumn 57, Issue 3, 2006, Pages 221-226

  Faine, L A ^a   Rodrigues, H G ^a   Galhardi, C M ^a   Ebaid, G M X ^a   Diniz, Y S ^a   Fernandes, A A H ^a   Novelli, E L B ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Antioxidant enzymes; Butylated hydroxytoluene; Cholesterol; Energy metabolism; Heart; Lipid peroxidation; Oxidative stress; Serum lipids; Triacylglycerols

Indexed keywords

BUTYLCRESOL; HYDROPEROXIDE DERIVATIVE; LACTATE DEHYDROGENASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; ENERGY METABOLISM; ENZYME ACTIVITY; HEART; HEART MUSCLE METABOLISM; HEART WEIGHT; LIPID BLOOD LEVEL; LIPID PEROXIDATION; LIPOPROTEIN BLOOD LEVEL; MALE; NONHUMAN; OXIDATIVE STRESS; RAT; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT GAIN;

ANIMALIA; RATTUS NORVEGICUS;

EID: 30344482241     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etp.2005.10.001     Document Type: Article

References (42)

1. P.M. Abuja, and R. Albertini Methods for monitoring oxidative stress, lipid peroxidation and oxidation resistance of lipoproteins Clin Chim Acta 306 2001 1 17
2. H. Aebi H.V. Bergmeyer Methods of enzymatic analysis 1974 Verloy Chemia New York, Weinheim
3. Y.C. Awasthi, C.A. Partridge, and D.D. Dao Effect of butylated hydroxytoluene on glutathione-S-tranferase and glutathione peroxidase activities in rat liver Biochem Pharmacol 32 1983 1197 1200
4. A. Bass, P.E. Brdicka, P. Eyer, S. Hofer, and D. Pette Metabolic differentiation of distinct muscle types at the level of enzymatic organization Eur J Biochem 10 1969 198 206
5. J.L. Bolton, and J.A. Thompson Oxidation of butylated hydroxytoluene to toxic metabolites. Factors influencing hydroxylation and quinone methide formation by hepatic and pulmonary microsomes Drug Matabol Disp 19 1991 467 472
6. J.L. Bolton, H. Sevestre, B.O. Ibe, and J.A. Thompson Formation and reactivity of alternative quinone methides from butylated hydroxytoluene: possible explanation for species-specific pneumotoxicity Chem Res Toxicol 3 1990 65 70
7. P. Brizzi, G. Tonoio, F. Carusillo, M. Malaguarnera, M. Maioli, and S. Musumeci Plasma lipid composition and LDL oxidation Clin Chem Lab Med 41 2003 56 60
8. C. Ceconi, A. Boraso, A. Cargnoni, and R. Ferrari Oxidative stress in cardiovascular disease: myth or fact? Arch Biochem Biophys 420 2003 217 221
9. K. Chen, S.R. Thomas, and J.F. Keaney Jr. Beyond LDL oxidation: ROS in vascular signal transduction Free Rad Biol Med 35 2003 117 132
10. N. Cotelle Role of flavonoids in oxidative stress Curr Top Med Chem 1 2001 569 590
11. Y.S. Diniz, L.A. Faine, J.A. Almeida, M.D.P. Silva, B.O. Ribas, and E.L.B. Novelli Toxicity of dietary restriction of fat enriched diets on cardiac tissue Food Chem Toxicol 40 2002 1893 1899
12. K. Doi, F. Sawada, G. Toda, S. Yamachika, S. Seto, Y. Urata, Y. Ihara, N. Sakata, N. Taniguchi, T. Kondo, and K. Yano Alteration of antioxidants during the progression of heart disease in streptozotocin-induced diabetic rats Free Rad Res 34 2001 251 261
13. W. Droge Free radicals in the physiological control of cell function Physiol Rev 82 2002 47 95
14. L.A. Faine, Y.S. Diniz, J.A. Almeida, E.L.B. Novelli, and B.O. Ribas Toxicity of ad libitum overfeeding: effects on cardiac tissue Foof Chem Toxicol 40 2002 663 668
15. L.A. Faine, A.C. Cicogna, Y.S. Diniz, J.A. Almeida, R.C. Burneiko, H.G. Rodrigues, and E.L.B. Novelli Dietary restriction: metabolic shifting for cardiac health J Nutr Environ Med 13 2003 25 31
16. R.S. Farag, G.S. El-Baroty, and A.M. Basuny Safety evaluation of olive phenolic compounds as natural antioxidants Int J Food Sci Nutr 54 2003 159 174
17. T.M. Forte, G. Subbanagounder, J.A. Berliner, P.J. Blanche, A.O. Clermont, and Z. Jia Altered activities of anti-atherogenic enzymes LCAT, paraoxonase, and platelet-activating factor acetylhydrolase in atherosclerosis-susceptible mice J Lipid Res 43 2002 477 485
18. W.T. Friedewald, R.I. Levy, and S. Fredrickson D Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge Clin Chem 18 1972 499 502
19. Z.Y. Jiang, A.C.S. Woollard, and S. Wolf Lipid hydroperoxide measurement by oxidation of Fe2+ in the presence of xylenol orange. Comparison with TBA assay and on iodometric method Lipids 26 1991 853 856
20. S. Kawano, T. Nakao, and K. Hiraga Species and strain differences in the butylated hydroxytoluene (BHT)-producing induction of hepatic drug oxidation enzymes Jpn J Pharmacol 30 1980 861 870
21. L. Kisley, B.S. Barrett, L.D. Dwyer-Nield, A.K. Bauer, D.C. Thompson, and A.M. Malkinson Celecoxib reduces pulmonary inflammation but not lung tumorigenesis in mice Carcinogenesis 23 2002 1653 1660
22. T.M. Lewin, and R.A. Coleman Regulation of myocardial triacylglycerol synthesis and metabolism Biochim Biophys Acta 1694 2003 63 75
23. M. Lopes-Virella, P. Stone, S. Ellis, and J.A. Cowell Cholesterol determination in high-density lipoprotein separated by three methods Clin Chem 23 1977 882 884
24. O.H. Lowry, N.L. Rosebrough, A.L. Farr, and R.J. Randall Protein mensurement with the Folin-phenol reagent J Biol Chem 193 1951 265 275
25. P.L. Luz, and S.R. Coimbra Wine, alcohol and atherosclerosis: clinical evidences and mechanisms Braz J Med Biol Res 37 2004 1275 1295
26. R.A. Moura Técnicas de laboratório 1982 Atheneu Editora São Paulo
27. Y. Nakagawa Effects of buthionine sulfoximine and cysteine on the hepatotoxicity of butylated hydroxytoluene in rats Toxicol Lett 37 1987 251 256
28. Y. Nakagawa, and K. Tayama Nephrotoxicity of butylated hydroxytoluene in Phenobarbital-pretreated male rats Arch Toxicol 61 1988 359 365
29. W. Nakamura, S. Hojoda, and K. Hayashi Purification and properties of rat liver glutathione peroxidase Biochem Biophys Acta 358 1974 251 261
30. Y.I. Nishiyama, N. Haramaki, N. Yoshida, and T. Imaizumi Oxidative stress is related to exercise intolerance in patients with heart failure Am Heart J 135 1998 115 120
31. G.R. Norman, and D.L. Streiner Biostatistics - the bare essentials 1994 Mosby Book St. Louis
32. E.L.B. Novelli, A.A.H. Fernandes, Y.S. Diniz, J.A. Almeida, L.A. Faine, and B.O. Ribas The adverse effect of a high-energy dense diet on cardiac tissue J Nutr Environ Med 12 2002 287 294
33. S. Pucheu, C. Coudray, N. Tresallet, A. Favier, and J. Leiris Effect of dietary antioxidant trace element supply on cardiac tolerance to ischemia-reperfusion in the rat J Mol Cell Cardiol 27 1995 2303 2314
34. A.Z. Resnick, and L. Packer Oxidative damage to proteins: spectrophotometric method for carbonyl assay Methods Enzimol 233 1994 357 363
35. H.N. Sabbah, and C.W. Stanley Partial fatty acid oxidation inhibitors: a potentially new class of drugs for heart failure Eur J Heart Fail 4 2003 3 6 (Editorial)
36. K. Satoh Serum lipid peroxide in cerebrovascular disorders determined by a colorimetric method Clin Chim Acta 90 1978 37 43
37. C.M. Siman, and U.J. Eriksson Effect of butylated hydroxytoluene on alpha-tocopherol in livre and adipose tissue of rats Toxicol Lett 87 1996 103 108
38. R.S. Sohal, and R. Weindruch Oxidative stress, caloric restriction and aging Science 273 1996 59 63
39. R. Tamizhselvi, T. Samikkannu, and S. Niranjali Pulmonary phospholipids changes induced by butylated hydroxytoluene, an antioxidant, in rats Indian J Exp Biol 33 1995 796 797
40. P. Therond, D. Rousselot, A. Spraul, M. Conti, and A. Legrand Biomarkers of oxidative stress: an analytical approach Curr Opin Clin Nutr Met Care 3 2000 373 384
41. Z. Tu, and M.W. Anders Up-regulation of glutamate cysteine ligase gene expression by butylated hydroxytoluene is mediated by transcription factor AP-1 Biochem Biophys Res Comm 244 1998 801 805
42. H. Witschi, S. Kacew, B.K. Tsang, and D. Willianson Biochemical parameters of BHT-induced cell growth in mouse lung Chem-Biol Interactions 12 1976 29 40