메뉴 건너뛰기




Volumn 448, Issue , 2014, Pages 33-42

Human herpesvirus-6B protein U19 contains a p53 BOX I homology motif for HDM2 binding and p53 stabilization

Author keywords

HDM2; Human herpesvirus 6B; P53; U19; Virus cell interactions

Indexed keywords

PROTEIN MDM2; PROTEIN P53; U19 PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN;

EID: 84886303984     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2013.10.002     Document Type: Article
Times cited : (2)

References (38)
  • 5
    • 35748977117 scopus 로고    scopus 로고
    • Stabilization of p53 in human cytomegalovirus-initiated cells is associated with sequestration of HDM2 and decreased p53 ubiquitination
    • Chen Z., Knutson E., Wang S., Martinez L.A., Albrecht T. Stabilization of p53 in human cytomegalovirus-initiated cells is associated with sequestration of HDM2 and decreased p53 ubiquitination. Journal of Biological Chemistry 2007, 282:29284-29295.
    • (2007) Journal of Biological Chemistry , vol.282 , pp. 29284-29295
    • Chen, Z.1    Knutson, E.2    Wang, S.3    Martinez, L.A.4    Albrecht, T.5
  • 7
    • 66149089877 scopus 로고    scopus 로고
    • The presence of p53 influences the expression of multiple human cytomegalovirus genes at early times postinfection
    • Hannemann H., Rosenke K., O'Dowd J.M., Fortunato E.A. The presence of p53 influences the expression of multiple human cytomegalovirus genes at early times postinfection. Journal of Virology 2009, 83:4316-4325.
    • (2009) Journal of Virology , vol.83 , pp. 4316-4325
    • Hannemann, H.1    Rosenke, K.2    O'Dowd, J.M.3    Fortunato, E.A.4
  • 10
    • 38349076013 scopus 로고    scopus 로고
    • Human herpesvirus 6B U19 protein is a PML-regulated transcriptional activator that localizes to nuclear foci in a PML-independent manner
    • Kofod-Olsen E., Ross-Hansen K., Mikkelsen J.G., Höllsberg P. Human herpesvirus 6B U19 protein is a PML-regulated transcriptional activator that localizes to nuclear foci in a PML-independent manner. Journal of General Virology 2008, 89:106-116.
    • (2008) Journal of General Virology , vol.89 , pp. 106-116
    • Kofod-Olsen, E.1    Ross-Hansen, K.2    Mikkelsen, J.G.3    Höllsberg, P.4
  • 16
    • 0348134742 scopus 로고    scopus 로고
    • Mono- versus polyubiquitination: differential control of p53 fate by Mdm2
    • Li M., Brooks C.L., Wu-Baer F., Chen D., Baer R., Gu W. Mono- versus polyubiquitination: differential control of p53 fate by Mdm2. Science 2003, 302:1972-1975.
    • (2003) Science , vol.302 , pp. 1972-1975
    • Li, M.1    Brooks, C.L.2    Wu-Baer, F.3    Chen, D.4    Baer, R.5    Gu, W.6
  • 19
    • 70449380737 scopus 로고    scopus 로고
    • Direct Repeat 6 from human herpesvirus-6B encodes a nuclear protein that forms a complex with the viral DNA processivity factor p41
    • Schleimann M.H., Møller J.M., Kofod-Olsen E., Höllsberg P. Direct Repeat 6 from human herpesvirus-6B encodes a nuclear protein that forms a complex with the viral DNA processivity factor p41. PLoS ONE 2009, 4:e7457.
    • (2009) PLoS ONE , vol.4
    • Schleimann, M.H.1    Møller, J.M.2    Kofod-Olsen, E.3    Höllsberg, P.4
  • 20
    • 65249100143 scopus 로고    scopus 로고
    • Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy
    • Shangary S., Wang S. Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy. Annual Review of Pharmacology and Toxicology 2009, 49:223-241.
    • (2009) Annual Review of Pharmacology and Toxicology , vol.49 , pp. 223-241
    • Shangary, S.1    Wang, S.2
  • 21
    • 0034142034 scopus 로고    scopus 로고
    • The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites
    • Shieh S.Y., Ahn J., Tamai K., Taya Y., Prives C. The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. Genes & Development 2000, 14:289-300.
    • (2000) Genes & Development , vol.14 , pp. 289-300
    • Shieh, S.Y.1    Ahn, J.2    Tamai, K.3    Taya, Y.4    Prives, C.5
  • 22
    • 0037047345 scopus 로고    scopus 로고
    • The conformationally flexible S9-S10 linker region in the core domain of p53 contains a novel MDM2 binding site whose mutation increases ubiquitination of p53 in vivo
    • Shimizu H., Burch L.R., Smith A.J., Dornan D., Wallace M., Ball K.L., Hupp T.R. The conformationally flexible S9-S10 linker region in the core domain of p53 contains a novel MDM2 binding site whose mutation increases ubiquitination of p53 in vivo. Journal of Biological Chemistry 2002, 277:28446-28458.
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 28446-28458
    • Shimizu, H.1    Burch, L.R.2    Smith, A.J.3    Dornan, D.4    Wallace, M.5    Ball, K.L.6    Hupp, T.R.7
  • 23
    • 26444620118 scopus 로고    scopus 로고
    • Human herpesvirus 6 open reading frame U14 protein and cellular p53 interact with each other and are contained in the virion
    • Takemoto M., Koike M., Mori Y., Yonemoto S., Sasamoto Y., Kondo K., Uchiyama Y., Yamanishi K. Human herpesvirus 6 open reading frame U14 protein and cellular p53 interact with each other and are contained in the virion. Journal of Virology 2005, 79:13037-13046.
    • (2005) Journal of Virology , vol.79 , pp. 13037-13046
    • Takemoto, M.1    Koike, M.2    Mori, Y.3    Yonemoto, S.4    Sasamoto, Y.5    Kondo, K.6    Uchiyama, Y.7    Yamanishi, K.8
  • 24
    • 1842854077 scopus 로고    scopus 로고
    • Productive human herpesvirus 6 infection causes aberrant accumulation of p53 and prevents apoptosis
    • Takemoto M., Mori Y., Ueda K., Kondo K., Yamanishi K. Productive human herpesvirus 6 infection causes aberrant accumulation of p53 and prevents apoptosis. Journal of General Virology 2004, 85:869-879.
    • (2004) Journal of General Virology , vol.85 , pp. 869-879
    • Takemoto, M.1    Mori, Y.2    Ueda, K.3    Kondo, K.4    Yamanishi, K.5
  • 26
    • 67949120312 scopus 로고    scopus 로고
    • Human herpesvirus-6B induces expression of the human endogenous retrovirus K18-encoded superantigen
    • Turcanova V.L., Bundgaard B., Höllsberg P. Human herpesvirus-6B induces expression of the human endogenous retrovirus K18-encoded superantigen. Journal of Clinical Virology 2009, 46:15-19.
    • (2009) Journal of Clinical Virology , vol.46 , pp. 15-19
    • Turcanova, V.L.1    Bundgaard, B.2    Höllsberg, P.3
  • 29
    • 65349103899 scopus 로고    scopus 로고
    • Blinded by the light: the growing complexity of p53
    • Vousden K.H., Prives C. Blinded by the light: the growing complexity of p53. Cell 2009, 137:413-431.
    • (2009) Cell , vol.137 , pp. 413-431
    • Vousden, K.H.1    Prives, C.2
  • 33
    • 0027403891 scopus 로고
    • IgG antibodies to human herpesvirus-6 in young children: changes in avidity of antibody correlate with time after infection
    • Ward K.N., Gray J.J., Fotheringham M.W., Sheldon M.J. IgG antibodies to human herpesvirus-6 in young children: changes in avidity of antibody correlate with time after infection. Journal of Medical Virology 1993, 39:131-138.
    • (1993) Journal of Medical Virology , vol.39 , pp. 131-138
    • Ward, K.N.1    Gray, J.J.2    Fotheringham, M.W.3    Sheldon, M.J.4
  • 35
    • 33645787830 scopus 로고    scopus 로고
    • Evidence that the human cytomegalovirus IE2-86 protein binds mdm2 and facilitates mdm2 degradation
    • Zhang Z., Evers D.L., McCarville J.F., Dantonel J.C., Huong S.M., Huang E.S. Evidence that the human cytomegalovirus IE2-86 protein binds mdm2 and facilitates mdm2 degradation. Journal of Virology 2006, 80:3833-3843.
    • (2006) Journal of Virology , vol.80 , pp. 3833-3843
    • Zhang, Z.1    Evers, D.L.2    McCarville, J.F.3    Dantonel, J.C.4    Huong, S.M.5    Huang, E.S.6
  • 36
    • 13744251701 scopus 로고    scopus 로고
    • Human herpesvirus 6B induces cell cycle arrest concomitant with p53 phosphorylation and accumulation in T cells
    • Øster B., Bundgaard B., Höllsberg P. Human herpesvirus 6B induces cell cycle arrest concomitant with p53 phosphorylation and accumulation in T cells. Journal of Virology 2005, 79:1961-1965.
    • (2005) Journal of Virology , vol.79 , pp. 1961-1965
    • Øster, B.1    Bundgaard, B.2    Höllsberg, P.3
  • 37
    • 0036317961 scopus 로고    scopus 로고
    • Viral gene expression patterns in human herpesvirus 6B-infected T cells
    • Øster B., Höllsberg P. Viral gene expression patterns in human herpesvirus 6B-infected T cells. Journal of Virology 2002, 76:7578-7586.
    • (2002) Journal of Virology , vol.76 , pp. 7578-7586
    • Øster, B.1    Höllsberg, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.