HHV-6 and EBV DNA quantitation in lymph nodes of 86 patients with Hodgkin's lymphoma

Journal of Medical Virology

Volumn 79, Issue 9, 2007, Pages 1349-1356

  Lacroix, Aurélie ^a,b   Jaccard, Arnaud ^b   Rouzioux, Christine ^c   Piguet, Christophe ^b   Petit, Barbara ^b   Bordessoule, Dominique ^b   Ranger Rogez, Sylvie ^a,b  

^a UNIVERSITY OF LIMOGES   (France)

^b DUPUYTREN UNIVERSITY HOSPITAL   (France)

^c HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

Epstein Barr virus (EBV); Hodgkin's lymphoma; Human herpesvirus 6 (HHV 6); LMP 1; Real time PCR

Indexed keywords

PROTEIN LMP1; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS PROTEIN;

ADOLESCENT; ADULT; AGED; ARTICLE; EPSTEIN BARR VIRUS; FEMALE; FOLLOW UP; HISTOPATHOLOGY; HODGKIN DISEASE; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 6; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE BIOPSY; MAJOR CLINICAL STUDY; MALE; NONHUMAN; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SCHOOL CHILD; STATISTICAL ANALYSIS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CHILD; DNA, VIRAL; FEMALE; FOLLOW-UP STUDIES; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 4, HUMAN; HERPESVIRUS 6, HUMAN; HODGKIN DISEASE; HUMANS; LYMPH NODES; MALE; MIDDLE AGED; VIRAL MATRIX PROTEINS;

HERPESVIRIDAE; HUMAN HERPESVIRUS 4; HUMAN HERPESVIRUS 6; SIMPLEXVIRUS;

EID: 34547129070     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.20868     Document Type: Article

References (39)

1. Ambinder RF. 2003. Epstein-Barr virus-associated lymphoproliferative disorders. Rev Clin Exp Hematol 7:362-374.
2. Braun DK, Dominguez G, Pellett PE. 1997. Human herpesvirus 6. Clin Microbiol Rev 10:521-567.
3. Brauninger A, Schmitz R, Bechtel D, Renne C, Hansmann ML, Kuppers R. 2006. Molecular biology of Hodgkin's and Reed/Sternberg cells in Hodgkin's lymphoma. Int J Cancer 118:1853-1861.
4. Campadelli-Fiume G, Mirandola P, Menotti L. 1999. Human herpes-virus 6: An emerging pathogen. Emerg Infect Dis 5:353-366.
5. Caserta MT, Mock DJ, Dewhurst S. 2001. Human herpesvirus 6. Clin Infect Dis 33:829-833.
6. Chan KH, Tam JS, Peiris JS, Seto WH, Ng MH. 2001. Epstein-Barr virus (EBV) infection in infancy. J Clin Virol 21:57-62.
7. Chang KC, Khen NT, Jones D, Su IJ. 2005. Epstein-Barr virus is associated with all histological subtypes of Hodgkin lymphoma in Vietnamese children with special emphasis on the entity of lymphocyte predominance subtype. Hum Pathol 36:747-755.
8. Claviez A, Tiemann M, Luders H, Krams M, Parwaresch R, Schellong G, Dorffel W. 2005. Impact of latent Epstein-Barr virus infection on outcome in children and adolescents with Hodgkin's lymphoma. J Clin Oncol 23:4048-4056.
9. Collot S, Petit B, Bordessoule D, Alain S, Touati M, Denis F, Ranger-Rogez S. 2002. Real-time PCR for quantification of human herpesvirus 6 DNA from lymph nodes and saliva. J Clin Microbiol 40:2445-2451.
10. De Bolle L, Van Loon J, De Clercq E, Naesens L. 2005. Quantitative analysis of human herpesvirus 6 cell tropism. J Med Virol 75:76-85.
11. Flano E, Jia Q, Moore J, Woodland DL, Sun R, Blackman MA. 2005. Early establishment of gamma-herpesvirus latency: Implications for immune control. J Immunol 174:4972-4978.
12. Harris NL, Jaffe ES, Diebold J, Flandrin G, Muller-Hermelink HK, Vardiman J, Lister TA, Bloomfield CD. 2000. The World Health Organization classification of neoplastic diseases of the haematopoietic and lymphoid tissues: Report of the clinical advisory committee meeting, Airlie House, Virginia, November 1997. Histopathology 36:69-86.
13. Hemsrichart V, Pintong J. 2005. Association of the Epstein-Barr viruses with Hodgkin lymphoma: An analysis of pediatric cases in Thailand. J Med Assoc Thai 88:782-787.
14. Herbst H, Dallenbach F, Hummel M, Niedobitek G, Pileri S, Muller-Lantzsch N, Stein H. 1991. Epstein-Barr virus latent membrane protein expression in Hodgkin and Reed-Sternberg cells. Proc Natl Acad Sci U S A 88:4766-4770.
15. Herling M, Rassidakis GZ, Medeiros LJ, Vassilakopoulos TP, Kliche KO, Nadali G, Viviani S, Bonfante V, Giardini R, Chilosi M, Kittas C, Gianni AM, Bonadonna G, Pizzolo G, Pangalis GA, Cabanillas F, Sarris AH. 2003. Expression of Epstein-Barr virus latent membrane protein-1 in Hodgkin and Reed-Sternberg cells of classical Hodgkin's lymphoma: Associations with presenting features, serum interleukin 10 levels, and clinical outcome. Clin Cancer Res 9:2114-2120.
16. Hsu JL, Glaser SL. 2000. Epstein-Barr virus-associated malignancies: Epidemiologic patterns and etiologic implications. Crit Rev Oncol Hematol 34:27-53.
17. Jarrett RF. 2002. Viruses and Hodgkin's lymphoma. Ann Oncol 13:23-29.
18. Jarrett RF, Stark GL, White J, Angus B, Alexander FE, Krajewski AS, Freeland J, Taylor GM, Taylor PR. 2005. Impact of tumor Epstein-Barr virus status on presenting features and outcome in age-defined subgroups of patients with classic Hodgkin lymphoma: A population-based study. Blood 106:2444-2451.
19. Joske DJ, Emery-Goodman A, Bachmann F, Odermatt B, Knecht H. 1992. Epstein-Barr virus burden in Hodgkin's disease is related to latent membrane protein gene expression but not to active viral replication. Blood 80:2610-2613.
20. Kashanchi F, Thompson J, Sadaie MR, Doniger J, Duvall J, Brady JN, Rosenthal LJ. 1994. Transcriptional activation of minimal HIV-1 promoter by ORF-1 protein expressed from the SalI-L fragment of human herpesvirus 6. Virology 201:95-106.
21. Keegan TH, Glaser SL, Clarke CA, Gulley ML, Craig FE, Digiuseppe JA, Dorfman RF, Mann RB, Ambinder RF. 2005. Epstein-Barr virus as a marker of survival after Hodgkin's lymphoma: A population-based study. J Clin Oncol 23:7604-7613.
22. Khan G, Norton AJ, Slavin G. 1993. Epstein-Barr virus in Hodgkin disease. Relation to age and subtype. Cancer 71:3124-3129.
23. Krueger GR, Guenther A, Knuefermann R, Kluppelberg U, Luka J, Pearson GR, Ablashi DV, Juecker M, Tesch H. 1994. Human herpesvirus-6 (HHV-6) in Hodgkin's disease: Cellular expression of viral antigens as compared to oncogenes met and fes, tumor suppressor gene product p53, and interleukins 2 and 6. In Vivo 8:501-516.
24. Krueger GR, Huetter ML, Rojo J, Romero M, Cruz-Ortiz H. 2001. Human herpesviruses HHV-4 (EBV) and HHV-6 in Hodgkin's and Kikuchi's diseases and their relation to proliferation and apoptosis. Anticancer Res 21:2155-2161.
25. Middleton T, Sugden B. 1994. Retention of plasmid DNA in mammalian cells is enhanced by binding of the Epstein-Barr virus replication protein EB NA1. J Virol 68:4067-4071.
26. Murray PG, Young LS, Rowe M, Crocker J. 1992. Immunohistochemical demonstration of the Epstein-Barr virus-encoded latent membrane protein in paraffin sections of Hodgkin's disease. J Pathol 166:1-5.
27. Okuno T, Takahashi K, Balachandra K, Shiraki K, Yamanishi K, Takahashi M, Baba K. 1989. Seroepidemiology of human herpes-virus 6 infection in normal children and adults. J Clin Microbiol 27:651-653.
28. Pallesen G, Hamilton-Dutoit SJ, Rowe M, Young LS. 1991. Expression of Epstein-Barr virus latent gene products in tumour cells of Hodgkin's disease. Lancet 337:320-322.
29. Parkin DM, Bray F, Ferlay J, Pisani P. 2001. Estimating the world cancer burden: Globocan 2000. Int J Cancer 94:153-156.
30. Ranger-Rogez S, Lacroix A, Denis F, Bordessoule D. 2006. HHV-6 and the lympho-hematopoietic system. In: Krueger GRF, Ablashi DV, editors. Human herpesvirus-6 - general virology, epidemiology and clinical pathology, 2nd ed. Amsterdam: Elsevier. p 185-200.
31. Sambrook J, Fritsh EF, Maniatis T, editors. 1989. Molecular cloning: A laboratory manual, 2nd ed. New York: Cold Spring Harbor Laboratory.
32. Schmidt CA, Oettle H, Peng R, Binder T, Wilborn F, Huhn D, Siegert W, Herbst H. 2000. Presence of human beta- and gamma-herpes virus DNA in Hodgkin's disease. Leuk Res 24:865-870.
33. Serraino D, Piselli P, Angeletti C, Scuderi M, Ippolito G, Capobianchi MR. 2005. Infection with Epstein-Barr virus and cancer: An epidemiological review. J Biol Regul Homeost Agents 19:63-70.
34. Sumiyoshi Y, Kikuchi M, Ohshima K, Takeshita M, Eizuru Y, Minamishima Y. 1993. Analysis of human herpes virus-6 genomes in lymphoid malignancy in Japan. J Clin Pathol 46:1137-1138.
35. Valente G, Secchiero P, Lusso P, Abete MC, Jemma C, Reato G, Kerim S, Gallo RC, Palestra G. 1996. Human herpesvirus 6 and Epstein-Barr virus in Hodgkin's disease: A controlled study by polymerase chain reaction and in situ hybridization. Am J Pathol 149:1501-1510.
36. Wagner HJ, Bein G, Bitsch A, Kirchner H. 1992. Detection and quantification of latently infected B lymphocytes in Epstein-Barr virus-seropositive, healthy individuals by polymerase chain reaction. J Clin Microbiol 30:2826-2829.
37. Ward KN, Gray JJ, Fotheringham MW, Sheldon MJ. 1993. IgG antibodies to human herpesvirus-6 in young children: Changes in avidity of antibody correlate with time after infection. J Med Virol 39:131-138.
38. Young LS, Rickinson AB. 2004. Epstein-Barr virus: 40 years on. Nat Rev Cancer 4:757-768.
39. Zerr DM. 2006. Human herpesvirus 6: A clinical update. Herpes 13:20-24.