Perfluorooctanoic acid induces apoptosis through the p53-dependent mitochondrial pathway in human hepatic cells: A proteomic study

Toxicology Letters

Volumn 223, Issue 2, 2013, Pages 211-220

  Huang, Qingyu ^a   Zhang, Jie ^a   Martin, Francis L ^b   Peng, Siyuan ^a   Tian, Meiping ^a   Mu, Xiaoli ^a   Shen, Heqing ^a  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^b LANCASTER UNIVERSITY   (United Kingdom)

Author keywords

Apoptosis; Human hepatic cells; Mitochondrial pathway; P53; Perfluorooctanoic acid; Proteomics

Indexed keywords

ACTIN; ALPHA ACTIN; CATHEPSIN D; CYTOKERATIN 1; CYTOKERATIN 10; FK 506 BINDING PROTEIN; GLUCOSE REGULATED PROTEIN; GLUCOSE REGULATED PROTEIN 78; HEAT SHOCK PROTEIN 27; ISOCITRATE DEHYDROGENASE; KARYOPHERIN ALPHA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PERFLUOROOCTANOIC ACID; PROTEIN BAX; PROTEIN P53; RADIXIN; STAT3 PROTEIN; UBIQUINOL CYTOCHROME C REDUCTASE;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE M PHASE; CELL PROLIFERATION; CONTROLLED STUDY; FLOW CYTOMETRY; GEL ELECTROPHORESIS; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL; LIVER CELL CARCINOMA; LIVER TOXICITY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEOMICS; RISK ASSESSMENT; UPREGULATION; WESTERN BLOTTING;

APOPTOSIS; HUMAN HEPATIC CELLS; MITOCHONDRIAL PATHWAY; P53; PERFLUOROOCTANOIC ACID; PROTEOMICS;

APOPTOSIS; CAPRYLATES; CELL CYCLE CHECKPOINTS; CELL PROLIFERATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FLUOROCARBONS; GENE EXPRESSION PROFILING; HEPATOCYTES; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; LIVER; MITOCHONDRIA; OXIDATIVE STRESS; PROTEOME; PROTEOMICS; TUMOR SUPPRESSOR PROTEIN P53; TWO-DIMENSIONAL DIFFERENCE GEL ELECTROPHORESIS;

EID: 84886303120     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2013.09.002     Document Type: Article

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