Reactive oxygen species and mitochondria mediate the induction of apoptosis in human hepatoma HepG2 cells by the rodent peroxisome proliferator and hepatocarcinogen, perfluorooctanoic acid

Toxicology and Applied Pharmacology

Volumn 173, Issue 1, 2001, Pages 56-64

  Panaretakis, Theoharis ^a,b   Shabalina, Irina G ^a   Grandér, Dan ^b   Shoshan, Maria C ^b   Depierre, Joseph W ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Apoptosis; HepG2 cell line; Mitochondrial transmembrane potential; Perfluorooctanoic acid; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; CARCINOGEN; CASPASE 9; CYCLOSPORIN A; GLUTATHIONE; HYDROGEN PEROXIDE; PERFLUOROOCTANOIC ACID; PEROXISOME PROLIFERATOR; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

APOPTOSIS; ARTICLE; CELL STRAIN HEPG2; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MITOCHONDRION;

RODENTIA;

EID: 0035873322     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.2001.9159     Document Type: Article

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