메뉴 건너뛰기




Volumn 32, Issue 20, 2012, Pages 4237-4244

Heterogeneous nuclear ribonucleoprotein C1/C2 controls the metastatic potential of glioblastoma by Regulating PDCD4

Author keywords

[No Author keywords available]

Indexed keywords

ETOPOSIDE; MEMBRANE PROTEIN; MICRORNA; PROGRAMMED CELL DEATH 4; PROTEIN KINASE B; RIBONUCLEOPROTEIN; UNCLASSIFIED DRUG;

EID: 84868713197     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00443-12     Document Type: Article
Times cited : (108)

References (49)
  • 1
    • 41749113108 scopus 로고    scopus 로고
    • MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
    • Asangani IA, et al. 2008. MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 27:2128-2136.
    • (2008) Oncogene , vol.27 , pp. 2128-2136
    • Asangani, I.A.1
  • 2
    • 6344231276 scopus 로고    scopus 로고
    • Transformation suppressor protein Pdcd4 interferes with JNK-mediated phosphorylation of c-Jun and recruitment of the coactivator p300 by c-Jun
    • Bitomsky N, Bohm M, Klempnauer KH. 2004. Transformation suppressor protein Pdcd4 interferes with JNK-mediated phosphorylation of c-Jun and recruitment of the coactivator p300 by c-Jun. Oncogene 23:7484-7493.
    • (2004) Oncogene , vol.23 , pp. 7484-7493
    • Bitomsky, N.1    Bohm, M.2    Klempnauer, K.H.3
  • 3
    • 49649102818 scopus 로고    scopus 로고
    • siRNA-mediated knockdown of Pdcd4 expression causes upregulation of p21(Waf1/Cip1) expression
    • Bitomsky N, Wethkamp N, Marikkannu R, Klempnauer KH. 2008. siRNA-mediated knockdown of Pdcd4 expression causes upregulation of p21(Waf1/Cip1) expression. Oncogene 27:4820-4829.
    • (2008) Oncogene , vol.27 , pp. 4820-4829
    • Bitomsky, N.1    Wethkamp, N.2    Marikkannu, R.3    Klempnauer, K.H.4
  • 4
    • 60149088848 scopus 로고    scopus 로고
    • Origins and mechanisms of miRNAs and siRNAs
    • Carthew RW, Sontheimer EJ. 2009. Origins and mechanisms of miRNAs and siRNAs. Cell 136:642-655.
    • (2009) Cell , vol.136 , pp. 642-655
    • Carthew, R.W.1    Sontheimer, E.J.2
  • 5
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • Chan JA, Krichevsky AM, Kosik KS. 2005. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res. 65:6029-6033.
    • (2005) Cancer Res , vol.65 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 6
    • 0042524204 scopus 로고    scopus 로고
    • Loss of PDCD4 expression in human lung cancer correlates with tumour progression and prognosis
    • Chen Y, et al. 2003. Loss of PDCD4 expression in human lung cancer correlates with tumour progression and prognosis. J. Pathol. 200:640-646.
    • (2003) J. Pathol. , vol.200 , pp. 640-646
    • Chen, Y.1
  • 7
    • 82255185653 scopus 로고    scopus 로고
    • Identifying transcriptional start sites of human microRNAs based on high-throughput sequencing data
    • Chien CH, et al. 2011. Identifying transcriptional start sites of human microRNAs based on high-throughput sequencing data. Nucleic Acids Res. 39:9345-9356.
    • (2011) Nucleic Acids Res , vol.39 , pp. 9345-9356
    • Chien, C.H.1
  • 8
    • 0022520577 scopus 로고
    • Heterogeneous nuclear ribonucleoproteins, role inRNAsplicing
    • Choi YD, Grabowski PJ, Sharp PA, Dreyfuss G. 1986. Heterogeneous nuclear ribonucleoproteins: role inRNAsplicing. Science 231:1534-1539.
    • (1986) Science , vol.231 , pp. 1534-1539
    • Choi, Y.D.1    Grabowski, P.J.2    Sharp, P.A.3    Dreyfuss, G.4
  • 9
    • 42449086890 scopus 로고    scopus 로고
    • Interaction of heterogeneous nuclear ribonucleoprotein C1/C2 with a novel cis-regulatory element within p53 mRNA as a response to cytostatic drug treatment
    • Christian KJ, Lang MA, Raffalli-Mathieu F. 2008. Interaction of heterogeneous nuclear ribonucleoprotein C1/C2 with a novel cis-regulatory element within p53 mRNA as a response to cytostatic drug treatment. Mol. Pharmacol. 73:1558-1567.
    • (2008) Mol. Pharmacol. , vol.73 , pp. 1558-1567
    • Christian, K.J.1    Lang, M.A.2    Raffalli-Mathieu, F.3
  • 10
    • 0033598712 scopus 로고    scopus 로고
    • Differentially expressed protein Pdcd4 inhibits tumor promoter-induced neoplastic transformation
    • Cmarik JL, et al. 1999. Differentially expressed protein Pdcd4 inhibits tumor promoter-induced neoplastic transformation. Proc. Natl. Acad. Sci. U. S. A. 96:14037-14042.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 14037-14042
    • Cmarik, J.L.1
  • 11
    • 77952948062 scopus 로고    scopus 로고
    • Overexpression of miR-21 promotes an in vitro metastatic phenotype by targeting the tumor suppressor RHOB
    • Connolly EC, Van Doorslaer K, Rogler LE, Rogler CE. 2010. Overexpression of miR-21 promotes an in vitro metastatic phenotype by targeting the tumor suppressor RHOB. Mol. Cancer Res. 8:691-700.
    • (2010) Mol. Cancer Res. , vol.8 , pp. 691-700
    • Connolly, E.C.1    Van Doorslaer, K.2    Rogler, L.E.3    Rogler, C.E.4
  • 13
    • 33750325725 scopus 로고    scopus 로고
    • S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth
    • Dorrello NV, et al. 2006. S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth. Science 314:467-471.
    • (2006) Science , vol.314 , pp. 467-471
    • Dorrello, N.V.1
  • 14
    • 42249090353 scopus 로고    scopus 로고
    • miR-21 gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism
    • Fujita S, et al. 2008. miR-21 gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism. J. Mol. Biol. 378: 492-504.
    • (2008) J. Mol. Biol. , vol.378 , pp. 492-504
    • Fujita, S.1
  • 15
    • 77449149671 scopus 로고    scopus 로고
    • PDCD4 gene silencing in gliomas is associated with 5=CpG island methylation and unfavourable prognosis
    • Gao F, et al. 2009. PDCD4 gene silencing in gliomas is associated with 5=CpG island methylation and unfavourable prognosis. J. Cell. Mol. Med. 13:4257-4267.
    • (2009) J. Cell. Mol. Med. , vol.13 , pp. 4257-4267
    • Gao, F.1
  • 16
    • 38149139712 scopus 로고    scopus 로고
    • Frequent loss of PDCD4 expression in human glioma, possible role in the tumorigenesis of glioma
    • Gao F, et al. 2007. Frequent loss of PDCD4 expression in human glioma: possible role in the tumorigenesis of glioma. Oncol. Rep. 17:123-128.
    • (2007) Oncol. Rep. , vol.17 , pp. 123-128
    • Gao, F.1
  • 18
    • 79959977098 scopus 로고    scopus 로고
    • Downregulation of Pdcd4 by mir-21 facilitates glioblastoma proliferation in vivo
    • Gaur AB, Holbeck SL, Colburn NH, Israel MA. 2011. Downregulation of Pdcd4 by mir-21 facilitates glioblastoma proliferation in vivo. Neuro Oncol. 13:580-590.
    • (2011) Neuro Oncol , vol.13 , pp. 580-590
    • Gaur, A.B.1    Holbeck, S.L.2    Colburn, N.H.3    Israel, M.A.4
  • 19
    • 2342501442 scopus 로고    scopus 로고
    • Programmed cell death protein 4 (PDCD4) acts as a tumor suppressor in neuroendocrine tumor cells
    • Goke R, et al. 2004. Programmed cell death protein 4 (PDCD4) acts as a tumor suppressor in neuroendocrine tumor cells. Ann. N. Y. Acad. Sci. 1014:220-221.
    • (2004) Ann. N. Y. Acad. Sci. , vol.1014 , pp. 220-221
    • Goke, R.1
  • 20
    • 67650538055 scopus 로고    scopus 로고
    • Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion
    • Huang TH, et al. 2009. Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion. J. Biol. Chem. 284:18515-18524.
    • (2009) J. Biol. Chem. , vol.284 , pp. 18515-18524
    • Huang, T.H.1
  • 21
    • 23844555119 scopus 로고    scopus 로고
    • MicroRNA gene expression deregulation in human breast cancer
    • Iorio MV, et al. 2005. MicroRNA gene expression deregulation in human breast cancer. Cancer Res. 65:7065-7070.
    • (2005) Cancer Res , vol.65 , pp. 7065-7070
    • Iorio, M.V.1
  • 22
    • 79954575702 scopus 로고    scopus 로고
    • Frizzled 4 regulates stemness and invasiveness of migrating glioma cells established by serial intracranial transplantation
    • Jin X, et al. 2011. Frizzled 4 regulates stemness and invasiveness of migrating glioma cells established by serial intracranial transplantation. Cancer Res. 71:3066-3075.
    • (2011) Cancer Res , vol.71 , pp. 3066-3075
    • Jin, X.1
  • 23
    • 68149165414 scopus 로고    scopus 로고
    • HuR recruits let-7/RISC to repress c-Myc expression
    • Kim HH, et al. 2009. HuR recruits let-7/RISC to repress c-Myc expression. Genes Dev. 23:1743-1748.
    • (2009) Genes Dev , vol.23 , pp. 1743-1748
    • Kim, H.H.1
  • 24
    • 0037219006 scopus 로고    scopus 로고
    • Heterogeneous nuclear ribonucleoprotein C modulates translation of c-myc mRNA in a cell cycle phase-dependent manner
    • Kim JH, et al. 2003. Heterogeneous nuclear ribonucleoprotein C modulates translation of c-myc mRNA in a cell cycle phase-dependent manner. Mol. Cell. Biol. 23:708-720.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 708-720
    • Kim, J.H.1
  • 26
    • 67449104909 scopus 로고    scopus 로고
    • The tumour suppressor Pdcd4, recent advances in the elucidation of function and regulation
    • Lankat-Buttgereit B, Goke R. 2009. The tumour suppressor Pdcd4: recent advances in the elucidation of function and regulation. Biol. Cell 101:309-317.
    • (2009) Biol. Cell , vol.101 , pp. 309-317
    • Lankat-Buttgereit, B.1    Goke, R.2
  • 27
    • 1142273385 scopus 로고    scopus 로고
    • Pdcd4 inhibits growth of tumor cells by suppression of carbonic anhydrase type II
    • Lankat-Buttgereit B, et al. 2004. Pdcd4 inhibits growth of tumor cells by suppression of carbonic anhydrase type II. Mol. Cell. Endocrinol. 214: 149-153.
    • (2004) Mol. Cell. Endocrinol. , vol.214 , pp. 149-153
    • Lankat-Buttgereit, B.1
  • 28
    • 77953249227 scopus 로고    scopus 로고
    • hnRNP C promotes APP translation by competing with FMRP for APP mRNA recruitment to P bodies
    • Lee EK, et al. 2010. hnRNP C promotes APP translation by competing with FMRP for APP mRNA recruitment to P bodies. Nat. Struct. Mol. Biol. 17:732-739.
    • (2010) Nat. Struct. Mol. Biol. , vol.17 , pp. 732-739
    • Lee, E.K.1
  • 29
    • 34447270490 scopus 로고    scopus 로고
    • Tumor suppressor Pdcd4 inhibits invasion/ intravasation and regulates urokinase receptor (u-PAR) gene expression via Sp-transcription factors
    • Leupold JH, et al. 2007. Tumor suppressor Pdcd4 inhibits invasion/ intravasation and regulates urokinase receptor (u-PAR) gene expression via Sp-transcription factors. Oncogene 26:4550-4562.
    • (2007) Oncogene , vol.26 , pp. 4550-4562
    • Leupold, J.H.1
  • 30
    • 67849103555 scopus 로고    scopus 로고
    • MicroRNA-21 targets LRRFIP1 and contributes to VM-26 resistance in glioblastoma multiforme
    • Li Y, et al. 2009. MicroRNA-21 targets LRRFIP1 and contributes to VM-26 resistance in glioblastoma multiforme. Brain Res. 1286:13-18.
    • (2009) Brain Res , vol.1286 , pp. 13-18
    • Li, Y.1
  • 31
    • 33645732219 scopus 로고    scopus 로고
    • Molecular pathology of malignant gliomas
    • Louis DN. 2006. Molecular pathology of malignant gliomas. Annu. Rev. Pathol. 1:97-117.
    • (2006) Annu. Rev. Pathol. , vol.1 , pp. 97-117
    • Louis, D.N.1
  • 32
    • 34249316905 scopus 로고    scopus 로고
    • RNA-binding proteins, modular design for efficient function
    • Lunde BM, Moore C, Varani G. 2007. RNA-binding proteins: modular design for efficient function. Nat. Rev. Mol. Cell. Biol. 8:479-490.
    • (2007) Nat. Rev. Mol. Cell. Biol. , vol.8 , pp. 479-490
    • Lunde, B.M.1    Moore, C.2    Varani, G.3
  • 33
    • 77955425756 scopus 로고    scopus 로고
    • Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis
    • Michlewski G, Caceres JF. 2010. Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis. Nat. Struct. Mol. Biol. 17: 1011-1018.
    • (2010) Nat. Struct. Mol. Biol. , vol.17 , pp. 1011-1018
    • Michlewski, G.1    Caceres, J.F.2
  • 34
    • 55049119136 scopus 로고    scopus 로고
    • Posttranscriptional regulation of miRNAs harboring conserved terminal loops
    • Michlewski G, Guil S, Semple CA, Caceres JF. 2008. Posttranscriptional regulation of miRNAs harboring conserved terminal loops. Mol. Cell 32: 383-393.
    • (2008) Mol. Cell , vol.32 , pp. 383-393
    • Michlewski, G.1    Guil, S.2    Semple, C.A.3    Caceres, J.F.4
  • 35
    • 29244472037 scopus 로고    scopus 로고
    • Akt phosphorylates and regulates Pdcd4 tumor suppressor protein
    • Palamarchuk A, et al. 2005. Akt phosphorylates and regulates Pdcd4 tumor suppressor protein. Cancer Res. 65:11282-11286.
    • (2005) Cancer Res , vol.65 , pp. 11282-11286
    • Palamarchuk, A.1
  • 36
    • 0027411587 scopus 로고
    • hnRNP proteins, localization and transport between the nucleus and the cytoplasm
    • Pinol-Roma S, Dreyfuss G. 1993. hnRNP proteins: localization and transport between the nucleus and the cytoplasm. Trends Cell Biol. 3:151-155.
    • (1993) Trends Cell Biol , vol.3 , pp. 151-155
    • Pinol-Roma, S.1    Dreyfuss, G.2
  • 37
    • 77956453805 scopus 로고    scopus 로고
    • Programmed cell death 4 loss increases tumor cell invasion and is regulated by miR-21 in oral squamous cell carcinoma
    • Reis PP, et al. 2010. Programmed cell death 4 loss increases tumor cell invasion and is regulated by miR-21 in oral squamous cell carcinoma. Mol. Cancer 9:238.
    • (2010) Mol. Cancer , vol.9 , pp. 238
    • Reis, P.P.1
  • 38
    • 33750600178 scopus 로고    scopus 로고
    • MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior
    • Roldo C, et al. 2006. MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior. J. Clin. Oncol. 24:4677-4684.
    • (2006) J. Clin. Oncol. , vol.24 , pp. 4677-4684
    • Roldo, C.1
  • 39
    • 20944435993 scopus 로고    scopus 로고
    • Regulation of urokinase receptor mRNA stability by hnRNP C in lung epithelial cells
    • Shetty S. 2005. Regulation of urokinase receptor mRNA stability by hnRNP C in lung epithelial cells. Mol. Cell. Biochem. 272:107-118.
    • (2005) Mol. Cell. Biochem. , vol.272 , pp. 107-118
    • Shetty, S.1
  • 40
    • 34247495591 scopus 로고    scopus 로고
    • miR-21-mediated tumor growth
    • Si ML, et al. 2007. miR-21-mediated tumor growth. Oncogene 26:2799-2803.
    • (2007) Oncogene , vol.26 , pp. 2799-2803
    • Si, M.L.1
  • 41
    • 67649277689 scopus 로고    scopus 로고
    • The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs
    • Trabucchi M, et al. 2009. The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs. Nature 459:1010-1014.
    • (2009) Nature , vol.459 , pp. 1010-1014
    • Trabucchi, M.1
  • 42
    • 80052041185 scopus 로고    scopus 로고
    • MicroRNA regulation by RNA-binding proteins and its implications for cancer
    • van Kouwenhove M, Kedde M, Agami R. 2011. MicroRNA regulation by RNA-binding proteins and its implications for cancer. Nat. Rev. Cancer 11:644-656.
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 644-656
    • van Kouwenhove, M.1    Kedde, M.2    Agami, R.3
  • 43
    • 33144490646 scopus 로고    scopus 로고
    • A microRNA expression signature of human solid tumors defines cancer gene targets
    • Volinia S, et al. 2006. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc. Natl. Acad. Sci. U. S. A. 103: 2257-2261.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 2257-2261
    • Volinia, S.1
  • 44
    • 84855860369 scopus 로고    scopus 로고
    • Tumour suppressive function and modulation of programmed cell death 4 (PDCD4) in ovarian cancer
    • doi, 10.1371/journal.pone.0030311
    • Wei N, Liu SS, Chan KK, Ngan HY. 2012. Tumour suppressive function and modulation of programmed cell death 4 (PDCD4) in ovarian cancer. PLoS One 7:e30311. doi:10.1371/journal.pone.0030311.
    • (2012) PLoS One , vol.7
    • Wei, N.1    Liu, S.S.2    Chan, K.K.3    Ngan, H.Y.4
  • 45
    • 70350087561 scopus 로고    scopus 로고
    • Loss of programmed cell death 4 (Pdcd4) associates with the progression of ovarian cancer
    • Wei NA, et al. 2009. Loss of programmed cell death 4 (Pdcd4) associates with the progression of ovarian cancer. Mol. Cancer 8:70.
    • (2009) Mol. Cancer , vol.8 , pp. 70
    • Wei, N.A.1
  • 46
    • 32044459728 scopus 로고    scopus 로고
    • Tumorigenesis suppressor Pdcd4 down-regulates mitogen-activated protein kinase kinase kinase kinase 1 expression to suppress colon carcinoma cell invasion
    • Yang HS, et al. 2006. Tumorigenesis suppressor Pdcd4 down-regulates mitogen-activated protein kinase kinase kinase kinase 1 expression to suppress colon carcinoma cell invasion. Mol. Cell. Biol 26:1297-1306.
    • (2006) Mol. Cell. Biol , vol.26 , pp. 1297-1306
    • Yang, H.S.1
  • 47
    • 79951500251 scopus 로고    scopus 로고
    • The ATM kinase induces microRNA biogenesis in the DNA damage response
    • Zhang X, Wan G, Berger FG, He X, Lu X. 2011. The ATM kinase induces microRNA biogenesis in the DNA damage response. Mol. Cell 41:371-383.
    • (2011) Mol. Cell , vol.41 , pp. 371-383
    • Zhang, X.1    Wan, G.2    Berger, F.G.3    He, X.4    Lu, X.5
  • 48
    • 77952963826 scopus 로고    scopus 로고
    • Reduction of miR-21 induces glioma cell apoptosis via activating caspase 9 and 3
    • Zhou X, et al. 2010. Reduction of miR-21 induces glioma cell apoptosis via activating caspase 9 and 3. Oncol. Rep. 24:195-201.
    • (2010) Oncol. Rep. , vol.24 , pp. 195-201
    • Zhou, X.1
  • 49
    • 40249092910 scopus 로고    scopus 로고
    • MicroRNA-21 targets tumor suppressor genes in invasion and metastasis
    • Zhu S, et al. 2008. MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res. 18:350-359.
    • (2008) Cell Res , vol.18 , pp. 350-359
    • Zhu, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.