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Volumn 42, Issue 5, 2013, Pages 1636-1643

The hepatitis B virus X protein downregulates NF-κB signaling pathways through decreasing the Notch signaling pathway in HBx-transformed L02 cells

Author keywords

Crosstalk; Hepatitis B virus X protein; Hepatocellular carcinoma; NF B; Notch

Indexed keywords

HEPATITIS B VIRUS X PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JAGGED1; NOTCH RECEPTOR; NOTCH1 RECEPTOR; PROTEIN P50; SMALL INTERFERING RNA; SYNAPTOTAGMIN I;

EID: 84876008146     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2013.1842     Document Type: Article
Times cited : (25)

References (34)
  • 2
    • 34250020201 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Epidemiology and molecular carcinogenesis
    • DOI 10.1053/j.gastro.2007.04.061, PII S0016508507007998
    • Hashem BE and Rudolph KL: Hepatocellular carcinoma epidemiology and molecular carcinogenesis. Gastroenterology 132: 2557-2576, 2007. (Pubitemid 46890874)
    • (2007) Gastroenterology , vol.132 , Issue.7 , pp. 2557-2576
    • El-Serag, H.B.1    Rudolph, K.L.2
  • 3
    • 0030902570 scopus 로고    scopus 로고
    • Hepatitis B virus X antigen in the pathogenesis of chronic infections and the development of hepatocellular carcinoma
    • Feitelson MA and Duan LX: Hepatitis B virus X antigen in the pathogenesis of chronic infections and the development of hepatocellular carcinoma. Am J Pathol 150: 1141-1157, 1997. (Pubitemid 27152632)
    • (1997) American Journal of Pathology , vol.150 , Issue.4 , pp. 1141-1157
    • Feitelson, M.A.1    Duan, L.-X.2
  • 4
    • 77956944503 scopus 로고    scopus 로고
    • Activated Notch signaling is required for hepatitis B virus X protein to promote proliferation and survival of human hepatic cells
    • Wang F, Zhou H, Xia X, et al: Activated Notch signaling is required for hepatitis B virus X protein to promote proliferation and survival of human hepatic cells. Cancer Lett 298: 64-73, 2010.
    • (2010) Cancer Lett , vol.298 , pp. 64-73
    • Wang, F.1    Zhou, H.2    Xia, X.3
  • 5
    • 1642382833 scopus 로고    scopus 로고
    • Notch signaling: Control of cell communication and cell fate
    • DOI 10.1242/dev.01074
    • Lai EC: Notch signaling: control of cell communication and cell fate. Development 131: 965-973, 2004. (Pubitemid 38380451)
    • (2004) Development , vol.131 , Issue.5 , pp. 965-973
    • Lai, E.C.1
  • 6
    • 33644752839 scopus 로고    scopus 로고
    • Notch signaling
    • DOI 10.1158/1078-0432.CCR-05-2570
    • Miele L: Notch signaling. Clin Cancer Res 12: 1074-1079, 2006. (Pubitemid 43342494)
    • (2006) Clinical Cancer Research , vol.12 , Issue.4 , pp. 1074-1079
    • Miele, L.1
  • 7
  • 8
    • 2942557122 scopus 로고    scopus 로고
    • Gamma-secretase: Proteasome of the membrane?
    • Kopan R and Ilagan MX: Gamma-secretase: proteasome of the membrane? Nat Rev Mol Cell Biol 5: 499-504, 2004.
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 499-504
    • Kopan, R.1    Ilagan, M.X.2
  • 9
    • 34447507691 scopus 로고    scopus 로고
    • Targeting transcription factors in acute leukemia in children
    • DOI 10.2174/138945007780830818
    • Berman JN and Look AT: Targeting transcription factors in acute leukemia in children. Curr Drug Targets 8: 727-737, 2007. (Pubitemid 47603402)
    • (2007) Current Drug Targets , vol.8 , Issue.6 , pp. 727-737
    • Berman, J.N.1    Look, A.T.2
  • 11
    • 0034902568 scopus 로고    scopus 로고
    • ic
    • DOI 10.1128/MCB.21.17.5925-5934.2001
    • Ronchini C and Capobianco AJ: Induction of cyclin D1 transcription and CDK2 activity by Notch(ic): implication for cell cycle disruption in transformation by Notch(ic). Mol Cell Biol 1: 5925-5934, 2001. (Pubitemid 32737809)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.17 , pp. 5925-5934
    • Ronchini, C.1    Capobianco, A.J.2
  • 12
    • 16244378910 scopus 로고    scopus 로고
    • Control of cell proliferation in the Drosophila eye by notch signaling
    • DOI 10.1016/j.devcel.2005.01.019, PII S1534580705000237
    • Baonza A and Freeman M: Control of cell proliferation in the Drosophila eye by Notch signaling. Dev Cell 8: 529-539, 2005. (Pubitemid 40450742)
    • (2005) Developmental Cell , vol.8 , Issue.4 , pp. 529-539
    • Baonza, A.1    Freeman, M.2
  • 15
    • 0034954277 scopus 로고    scopus 로고
    • X protein of hepatitis B virus modulates cytokine and growth factor related signal transduction pathways during the course of viral infections and hepatocarcinogenesis
    • DOI 10.1016/S1359-6101(00)00034-4, PII S1359610100000344
    • Diao J, Garces R and Richardson CD: X protein of hepatitis B virus modulates cytokine and growth factor related signal transduction pathways during the course of viral infections and hepatocarcinogenesis. Cytokine Growth Factor Rev 12: 189-205, 2001. (Pubitemid 32588145)
    • (2001) Cytokine and Growth Factor Reviews , vol.12 , Issue.2-3 , pp. 189-205
    • Diao, J.1    Garces, R.2    Richardson, C.D.3
  • 16
    • 0025176474 scopus 로고
    • Transactivation by the hepatitis B virus X protein depends on AP-2 and other transcription factors
    • Seto E, Mitchell PJ and Yen TS: Transactivation by the hepatitis B virus X protein depends on AP-2 and other transcription factors. Nature 344: 72-74, 1990.
    • (1990) Nature , vol.344 , pp. 72-74
    • Seto, E.1    Mitchell, P.J.2    Yen, T.S.3
  • 17
    • 0026526978 scopus 로고
    • Hepatitis B virus X protein activates transcription factor NF-kappa B without a requirement for protein kinase C
    • Lucito R and Schneider RJ: Hepatitis B virus X protein activates transcription factor NF-kappa B without a requirement for protein kinase C. J Virol 66: 983-991, 1992.
    • (1992) J Virol , vol.66 , pp. 983-991
    • Lucito, R.1    Schneider, R.J.2
  • 18
    • 0026623154 scopus 로고
    • Hepatitis B virus transactivator MHBst: Activation of NF-kappa B, selective inhibition by antioxidants and integral membrane localization
    • Meyer M, Caselmann WH, Schluter V, et al: Hepatitis B virus transactivator MHBst: activation of NF-kappa B, selective inhibition by antioxidants and integral membrane localization. EMBO J 11: 2991-3001, 1992.
    • (1992) EMBO J , vol.11 , pp. 2991-3001
    • Meyer, M.1    Caselmann, W.H.2    Schluter, V.3
  • 19
  • 20
    • 33845768987 scopus 로고    scopus 로고
    • Integrating cell-signalling pathways with NF-κB and IKK function
    • DOI 10.1038/nrm2083, PII NRM2083
    • Perkins ND: Integrating cell-signalling pathways with NF-kappaB and IKK function. Nat Rev Mol Cell Biol 8: 49-62, 2007. (Pubitemid 46012014)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.1 , pp. 49-62
    • Perkins, N.D.1
  • 21
    • 84055217307 scopus 로고    scopus 로고
    • Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits PPARγ expression and promotes pancreatic cancer progression in mice
    • Maniati E, Bossard M, Cook N, et al: Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits PPARγ expression and promotes pancreatic cancer progression in mice. J Clin Invest 121: 4685-4699, 2011.
    • (2011) J Clin Invest , vol.121 , pp. 4685-4699
    • Maniati, E.1    Bossard, M.2    Cook, N.3
  • 22
    • 84863553441 scopus 로고    scopus 로고
    • Genistein inhibits MDA-MB-231 triple-negative breast cancer cell growth by inhibiting NF-κB activity via the Notch-1 pathway
    • Pan H, Zhou W, He W, et al: Genistein inhibits MDA-MB-231 triple-negative breast cancer cell growth by inhibiting NF-κB activity via the Notch-1 pathway. Int J Mol Med 30: 337-343, 2012.
    • (2012) Int J Mol Med , vol.30 , pp. 337-343
    • Pan, H.1    Zhou, W.2    He, W.3
  • 23
    • 84859648359 scopus 로고    scopus 로고
    • Notch is an essential upstream regulator of NF-κB and is relevant for survival of Hodgkin and Reed-Sternberg cells
    • Schwarzer R, Dörken B and Jundt F: Notch is an essential upstream regulator of NF-κB and is relevant for survival of Hodgkin and Reed-Sternberg cells. Leukemia 26: 806-813, 2012.
    • (2012) Leukemia , vol.26 , pp. 806-813
    • Schwarzer, R.1    Dörken, B.2    Jundt, F.3
  • 24
    • 77950600868 scopus 로고    scopus 로고
    • Hepatitis B viral X protein alters the biological features and expressions of DNA repair enzymes in LO2 cells
    • Cheng B, Zheng Y, Guo XR, et al: Hepatitis B viral X protein alters the biological features and expressions of DNA repair enzymes in LO2 cells. Liver Int 30: 319-326, 2010.
    • (2010) Liver Int , vol.30 , pp. 319-326
    • Cheng, B.1    Zheng, Y.2    Guo, X.R.3
  • 25
    • 79958045469 scopus 로고    scopus 로고
    • Activated K-ras and INK4a/Arf deficiency cooperate during the development of pancreatic cancer by activation of Notch and NF-κB signaling pathways
    • Wang Z, Banerjee S, Ahmad A, et al: Activated K-ras and INK4a/Arf deficiency cooperate during the development of pancreatic cancer by activation of Notch and NF-κB signaling pathways. PLoS One 6: e20537, 2011.
    • (2011) PLoS One , vol.6
    • Wang, Z.1    Banerjee, S.2    Ahmad, A.3
  • 26
    • 61649106928 scopus 로고    scopus 로고
    • Infammation and liver cancer: New molecular links
    • Berasain C, Castillo J, Perugorria MJ, et al: Infammation and liver cancer: new molecular links. Ann NY Acad Sci 1155: 206-221, 2009.
    • (2009) Ann NY Acad Sci , vol.1155 , pp. 206-221
    • Berasain, C.1    Castillo, J.2    Perugorria, M.J.3
  • 27
    • 33846473749 scopus 로고    scopus 로고
    • Hepatitis B virus-induced concogenesis
    • Lupberger J and Hildt E: Hepatitis B virus-induced concogenesis. World J Gastroenterol 13: 74-81, 2007.
    • (2007) World J Gastroenterol , vol.13 , pp. 74-81
    • Lupberger, J.1    Hildt, E.2
  • 28
    • 33645457576 scopus 로고    scopus 로고
    • Constitutive activation of NF-kappaB in human hepatocellular carcinoma: Evidence of a cytoprotective role
    • Qiao L, Zhang H, Yu J, et al: Constitutive activation of NF-kappaB in human hepatocellular carcinoma: evidence of a cytoprotective role. Hum Gene Ther 17: 280-290, 2006.
    • (2006) Hum Gene Ther , vol.17 , pp. 280-290
    • Qiao, L.1    Zhang, H.2    Yu, J.3
  • 30
    • 33744978564 scopus 로고    scopus 로고
    • NF-kappaB and cancer: Mechanisms and targets
    • Karin M: NF-kappaB and cancer: mechanisms and targets. Mol Carcinog 45: 355-361, 2006.
    • (2006) Mol Carcinog , vol.45 , pp. 355-361
    • Karin, M.1
  • 31
    • 79751492851 scopus 로고    scopus 로고
    • NF-κB in the liver - Linking injury, fibrosis and hepatocellular carcinoma
    • Luedde T and Schwabe RF: NF-κB in the liver - linking injury, fibrosis and hepatocellular carcinoma. Nat Rev Gastroenterol Hepatol 8: 108-118, 2011.
    • (2011) Nat Rev Gastroenterol Hepatol , vol.8 , pp. 108-118
    • Luedde, T.1    Schwabe, R.F.2
  • 32
    • 0027332498 scopus 로고
    • The i kappa B proteins: Multifunctional regulators of Rel/NF-kappa B transcription factors
    • Beg AA and Baldwin JR: The I kappa B proteins: multifunctional regulators of Rel/NF-kappa B transcription factors. Genes Dev 7: 2064-2070, 1993.
    • (1993) Genes Dev , vol.7 , pp. 2064-2070
    • Beg, A.A.1    Baldwin, J.R.2
  • 33
    • 0043092181 scopus 로고    scopus 로고
    • Basal Expression of IκBα Is Controlled by the Mammalian Transcriptional Repressor RBP-J (CBF1) and Its Activator Notch1
    • DOI 10.1074/jbc.M211051200
    • Oakley F, Mann J, Ruddell RG, et al: Basal expression of IkappaBalpha is controlled by the mammalian transcriptional repressor RBP-J (CBF1) and its activator Notch1. J Biol Chem 278: 24359-24370, 2003. (Pubitemid 37548587)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.27 , pp. 24359-24370
    • Oakley, F.1    Mann, J.2    Ruddell, R.G.3    Pickford, J.4    Weinmaster, G.5    Mann, D.A.6
  • 34
    • 70349249979 scopus 로고    scopus 로고
    • Notch1 upregulates LPS-induced macrophage activation by increasing NF-kappaB activity
    • Monsalve E, Ruiz-García A, Baladrón V, et al: Notch1 upregulates LPS-induced macrophage activation by increasing NF-kappaB activity. Eur J Immunol 39: 2556-2570, 2009.
    • (2009) Eur J Immunol , vol.39 , pp. 2556-2570
    • Monsalve, E.1    Ruiz-García, A.2    Baladrón, V.3


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