-
1
-
-
0024382416
-
Cleavage of parathyroid hormone in macrophage endosomes illustrates a novel pathway for intracellular processing of proteins
-
Diment S., Martin K.J., Stahl P.D. Cleavage of parathyroid hormone in macrophage endosomes illustrates a novel pathway for intracellular processing of proteins. J. Biol. Chem. 1989, 264:13403-13406.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 13403-13406
-
-
Diment, S.1
Martin, K.J.2
Stahl, P.D.3
-
2
-
-
0018903866
-
Biosynthesis of lysosomal enzymes in fibroblasts. Synthesis as precursors of higher molecular weight
-
Hasilik A., Neufeld E.F. Biosynthesis of lysosomal enzymes in fibroblasts. Synthesis as precursors of higher molecular weight. J. Biol. Chem. 1980, 255:4937-4945.
-
(1980)
J. Biol. Chem.
, vol.255
, pp. 4937-4945
-
-
Hasilik, A.1
Neufeld, E.F.2
-
3
-
-
18044383481
-
Identification of proteases employed by dendritic cells in the processing of protein purified derivative (PPD)
-
Mohamadzadeh M., Mohamadzadeh H., Brammer M., Sestak K., Luftig R.B. Identification of proteases employed by dendritic cells in the processing of protein purified derivative (PPD). J. Immune. Based Ther. Vaccines 2004, 2:8-10.
-
(2004)
J. Immune. Based Ther. Vaccines
, vol.2
, pp. 8-10
-
-
Mohamadzadeh, M.1
Mohamadzadeh, H.2
Brammer, M.3
Sestak, K.4
Luftig, R.B.5
-
4
-
-
0037194598
-
Cathepsin-D affects multiple tumor progression steps in vivo:proliferation, angiogenesis and apoptosis
-
Berchem G., Glondu M., Gleizes M., Brouillet J.P., Vignon F., Garcia M., Liaudet-Coopman E. Cathepsin-D affects multiple tumor progression steps in vivo:proliferation, angiogenesis and apoptosis. Oncogene 2002, 21:5951-5955.
-
(2002)
Oncogene
, vol.21
, pp. 5951-5955
-
-
Berchem, G.1
Glondu, M.2
Gleizes, M.3
Brouillet, J.P.4
Vignon, F.5
Garcia, M.6
Liaudet-Coopman, E.7
-
5
-
-
17744366777
-
Angiostatin generation by cathepsin D secreted by human prostate carcinoma cells
-
Morikawa W., Yamamoto K., Ishikawa S., Takemoto S., Ono M., Fukushi J., Naito S., Nozaki C., Iwanaga S., Kuwano M. Angiostatin generation by cathepsin D secreted by human prostate carcinoma cells. J. Biol. Chem. 2000, 275:38912-38920.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 38912-38920
-
-
Morikawa, W.1
Yamamoto, K.2
Ishikawa, S.3
Takemoto, S.4
Ono, M.5
Fukushi, J.6
Naito, S.7
Nozaki, C.8
Iwanaga, S.9
Kuwano, M.10
-
6
-
-
0029782494
-
Cathepsin D protease mediates programmed cell death induced by interferon-gamma, Fas/APO-1 and TNF-alpha
-
Deiss L.P., Galinka H., Berissi H., Cohen O., Kimchi A. Cathepsin D protease mediates programmed cell death induced by interferon-gamma, Fas/APO-1 and TNF-alpha. EMBO J. 1996, 15:3861-3870.
-
(1996)
EMBO J.
, vol.15
, pp. 3861-3870
-
-
Deiss, L.P.1
Galinka, H.2
Berissi, H.3
Cohen, O.4
Kimchi, A.5
-
8
-
-
0041912315
-
Stress-induced apoptosis is impaired in cells with a lysosomal targeting defect but is not affected in cells synthesizing a catalytically inactive cathepsin D
-
Tardy C., Tyynelä J., Hasilik A., Levade T., Andrieu-Abadie N. Stress-induced apoptosis is impaired in cells with a lysosomal targeting defect but is not affected in cells synthesizing a catalytically inactive cathepsin D. Cell Death Differ. 2003, 10:1090-1100.
-
(2003)
Cell Death Differ.
, vol.10
, pp. 1090-1100
-
-
Tardy, C.1
Tyynelä, J.2
Hasilik, A.3
Levade, T.4
Andrieu-Abadie, N.5
-
9
-
-
53349091482
-
Cathepsin D protects human neuroblastoma cells from doxorubicin-induced cell death
-
Sagulenko V., Muth D., Sagulenko E., Paffhausen T., Schwab M., Westermann F. Cathepsin D protects human neuroblastoma cells from doxorubicin-induced cell death. Carcinogenesis 2008, 29:1869-1877.
-
(2008)
Carcinogenesis
, vol.29
, pp. 1869-1877
-
-
Sagulenko, V.1
Muth, D.2
Sagulenko, E.3
Paffhausen, T.4
Schwab, M.5
Westermann, F.6
-
10
-
-
20344387475
-
Autophagy: dual roles in life and death?
-
Baehrecke E.H. Autophagy: dual roles in life and death?. Nat. Rev. Mol. Cell. Biol. 2005, 6:505-510.
-
(2005)
Nat. Rev. Mol. Cell. Biol.
, vol.6
, pp. 505-510
-
-
Baehrecke, E.H.1
-
11
-
-
8344242220
-
Autophagy in health and disease: a double-edged sword
-
Shintani T., Klionsky D.J. Autophagy in health and disease: a double-edged sword. Science 2004, 306:990-995.
-
(2004)
Science
, vol.306
, pp. 990-995
-
-
Shintani, T.1
Klionsky, D.J.2
-
12
-
-
11144245626
-
The role of autophagy during the early neonatal starvation period
-
Kuma A., Hatano M., Matsui M., Yamamoto A., Nakaya H., Yoshimori T., Ohsumi Y., Tokuhisa T., Mizushima N. The role of autophagy during the early neonatal starvation period. Nature 2004, 432:1032-1036.
-
(2004)
Nature
, vol.432
, pp. 1032-1036
-
-
Kuma, A.1
Hatano, M.2
Matsui, M.3
Yamamoto, A.4
Nakaya, H.5
Yoshimori, T.6
Ohsumi, Y.7
Tokuhisa, T.8
Mizushima, N.9
-
13
-
-
1542513774
-
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is required for induction of autophagy during lumen formation in vitro
-
Mills K.R., Reginato M., Debnath J., Queenan B., Brugge J.S. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is required for induction of autophagy during lumen formation in vitro. Proc. Natl. Acad. Sci. 2004, 101:3438-3443.
-
(2004)
Proc. Natl. Acad. Sci.
, vol.101
, pp. 3438-3443
-
-
Mills, K.R.1
Reginato, M.2
Debnath, J.3
Queenan, B.4
Brugge, J.S.5
-
14
-
-
0036775488
-
Role of mitochondrial inner membrane permeabilization in necrotic cell death, apoptosis, and autophagy
-
Lemasters J.J., Qian T., He L., Kim J.S., Elmore S.P., Cascio W.E., Brenner D.A. Role of mitochondrial inner membrane permeabilization in necrotic cell death, apoptosis, and autophagy. Antioxid. Redox. Signal. 2002, 4:769-781.
-
(2002)
Antioxid. Redox. Signal.
, vol.4
, pp. 769-781
-
-
Lemasters, J.J.1
Qian, T.2
He, L.3
Kim, J.S.4
Elmore, S.P.5
Cascio, W.E.6
Brenner, D.A.7
-
15
-
-
74849088209
-
Proteomic analysis in NSAIDs-treated primary cardiomyocytes
-
Baek S.M., Ahn J.S., Noh H.S., Park J., Kang S.S., Kim D.R. Proteomic analysis in NSAIDs-treated primary cardiomyocytes. J. Proteomics 2010, 73:721-732.
-
(2010)
J. Proteomics
, vol.73
, pp. 721-732
-
-
Baek, S.M.1
Ahn, J.S.2
Noh, H.S.3
Park, J.4
Kang, S.S.5
Kim, D.R.6
-
16
-
-
58149391026
-
The reduced catalase expression in TrkA-induced cells leads to autophagic cell death via ROS accumulation
-
Dadakhujaev S., Noh H.S., Jung E.J., Hah Y.S., Kim C.J., Kim D.R. The reduced catalase expression in TrkA-induced cells leads to autophagic cell death via ROS accumulation. Exp. Cell Res. 2008, 314:3094-3106.
-
(2008)
Exp. Cell Res.
, vol.314
, pp. 3094-3106
-
-
Dadakhujaev, S.1
Noh, H.S.2
Jung, E.J.3
Hah, Y.S.4
Kim, C.J.5
Kim, D.R.6
-
17
-
-
0036270993
-
DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis
-
Bernstein C., Bernstein H., Payne C.M., Garewal H. DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis. Mutat. Res. 2002, 511:145-178.
-
(2002)
Mutat. Res.
, vol.511
, pp. 145-178
-
-
Bernstein, C.1
Bernstein, H.2
Payne, C.M.3
Garewal, H.4
-
18
-
-
14744272755
-
Glioblastoma cells deficient in DNA-dependent protein kinase are resistant to cell death
-
Chen G.G., Sin F.L.F., Leung B.C.S., Ng H.K., Poon W.S. Glioblastoma cells deficient in DNA-dependent protein kinase are resistant to cell death. J. Cell. Physiol. 2005, 203:127-132.
-
(2005)
J. Cell. Physiol.
, vol.203
, pp. 127-132
-
-
Chen, G.G.1
Sin, F.L.F.2
Leung, B.C.S.3
Ng, H.K.4
Poon, W.S.5
-
19
-
-
0032563825
-
Doxorubicin-induced cardiomyopathy
-
Singal P.K., Iliskovic N. Doxorubicin-induced cardiomyopathy. N. Engl. J. Med. 1998, 339:900-905.
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 900-905
-
-
Singal, P.K.1
Iliskovic, N.2
-
20
-
-
0033557922
-
1,25-Dihydroxyvitamin D3 enhances the susceptibility of breast cancer cells to doxorubicin-induced oxidative damage
-
Ravid A., Rocker D., Machlenkin A., Rotem C., Hochman A., Kessler-Icekson G., Liberman U.A., Koren R. 1,25-Dihydroxyvitamin D3 enhances the susceptibility of breast cancer cells to doxorubicin-induced oxidative damage. Cancer Res. 1999, 59:862-867.
-
(1999)
Cancer Res.
, vol.59
, pp. 862-867
-
-
Ravid, A.1
Rocker, D.2
Machlenkin, A.3
Rotem, C.4
Hochman, A.5
Kessler-Icekson, G.6
Liberman, U.A.7
Koren, R.8
-
21
-
-
0035478732
-
Involvement of nitric oxide released from microglia-macrophages in pathological changes of cathepsin D-deficient mice
-
Nakanishi H., Zhang J., Koike M., Nishioku T., Okamoto Y., Kominami E., von Figura K., Peters C., Yamamoto K., Saftig P., Uchiyama Y. Involvement of nitric oxide released from microglia-macrophages in pathological changes of cathepsin D-deficient mice. J. Neurosci. 2001, 21:7526-7533.
-
(2001)
J. Neurosci.
, vol.21
, pp. 7526-7533
-
-
Nakanishi, H.1
Zhang, J.2
Koike, M.3
Nishioku, T.4
Okamoto, Y.5
Kominami, E.6
von Figura, K.7
Peters, C.8
Yamamoto, K.9
Saftig, P.10
Uchiyama, Y.11
-
22
-
-
33847215777
-
Cathepsin D deficiency induces persistent neurodegeneration in the absence of Bax-dependent apoptosis
-
Shacka J.J., Klocke B.J., Young C., Shibata M., Olney J.W., Uchiyama Y., Saftig P., Roth K.A. Cathepsin D deficiency induces persistent neurodegeneration in the absence of Bax-dependent apoptosis. J. Neurosci. 2007, 27:2081-2090.
-
(2007)
J. Neurosci.
, vol.27
, pp. 2081-2090
-
-
Shacka, J.J.1
Klocke, B.J.2
Young, C.3
Shibata, M.4
Olney, J.W.5
Uchiyama, Y.6
Saftig, P.7
Roth, K.A.8
-
23
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
Kabeya Y., Mizushima N., Ueno T., Yamamoto A., Kirisako T., Noda T., Kominami E., Ohsumi Y., Yoshimori T. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J. 2000, 19:5720-5728.
-
(2000)
EMBO J.
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
Mizushima, N.2
Ueno, T.3
Yamamoto, A.4
Kirisako, T.5
Noda, T.6
Kominami, E.7
Ohsumi, Y.8
Yoshimori, T.9
-
24
-
-
20144373772
-
Inhibition of the DNA-dependent protein kinase catalytic subunit radiosensitizes malignant glioma cells by inducing autophagy
-
Daido S., Yamamoto A., Fujiwara K., Sawaya R., Kondo S., Kondo Y. Inhibition of the DNA-dependent protein kinase catalytic subunit radiosensitizes malignant glioma cells by inducing autophagy. Cancer Res. 2005, 65:4368-4375.
-
(2005)
Cancer Res.
, vol.65
, pp. 4368-4375
-
-
Daido, S.1
Yamamoto, A.2
Fujiwara, K.3
Sawaya, R.4
Kondo, S.5
Kondo, Y.6
-
25
-
-
0032580334
-
Potential role for Cathepsin D in p53-dependent tumor suppression and chemosensitivity
-
Wu G.S., Saftig P., Peters C., El-Deiry W.S. Potential role for Cathepsin D in p53-dependent tumor suppression and chemosensitivity. Oncogene 1998, 16:2177-2183.
-
(1998)
Oncogene
, vol.16
, pp. 2177-2183
-
-
Wu, G.S.1
Saftig, P.2
Peters, C.3
El-Deiry, W.S.4
-
26
-
-
0029083689
-
Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells
-
Saftig P., Hetman M., Schmahl W., Weber K., Heine L., Mossmann H., Köster A., Hess B., Evers M., von Figura K. Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells. EMBO J. 1995, 14:3599-3608.
-
(1995)
EMBO J.
, vol.14
, pp. 3599-3608
-
-
Saftig, P.1
Hetman, M.2
Schmahl, W.3
Weber, K.4
Heine, L.5
Mossmann, H.6
Köster, A.7
Hess, B.8
Evers, M.9
von Figura, K.10
-
27
-
-
28244493702
-
Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease)
-
Koike M., Shibata M., Waguri S., Yoshimura K., Tanida I., Kominami E., Gotow T., Peters C., von Figura K., Mizushima N., Saftig P., Uchiyama Y. Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease). Am. J. Pathol. 2005, 167:1713-1728.
-
(2005)
Am. J. Pathol.
, vol.167
, pp. 1713-1728
-
-
Koike, M.1
Shibata, M.2
Waguri, S.3
Yoshimura, K.4
Tanida, I.5
Kominami, E.6
Gotow, T.7
Peters, C.8
von Figura, K.9
Mizushima, N.10
Saftig, P.11
Uchiyama, Y.12
-
28
-
-
28544435485
-
Lysosomes and autophagy in cell death control
-
Kroemer G., Jaattela M. Lysosomes and autophagy in cell death control. Nat. Rev. Cancer 2005, 5:886-897.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 886-897
-
-
Kroemer, G.1
Jaattela, M.2
-
29
-
-
33645512801
-
Bcl-2 inhibition of autophagy: a new route to cancer?
-
Pattingre S., Levine B. Bcl-2 inhibition of autophagy: a new route to cancer?. Cancer Res. 2006, 66:2885-2888.
-
(2006)
Cancer Res.
, vol.66
, pp. 2885-2888
-
-
Pattingre, S.1
Levine, B.2
|