Regulation of multiple transcription factors by reactive oxygen species and effects of pro-inflammatory cytokines released during myocardial infarction on cardiac differentiation of embryonic stem cells

International Journal of Cardiology

Volumn 168, Issue 4, 2013, Pages 3458-3472

  Law, Sau Kwan ^a   Leung, Cecilia Sze Lee ^a   Yau, Ka Long ^a   Tse, Chi Lok ^a   Wong, Chun Kit ^a   Leung, Fung Ping ^a   Mascheck, Lena ^b   Huang, Yu ^a   Sauer, Heinrich ^b   Tsang, Suk Ying ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Cardiac differentiation; Cytokines; Embryonic stem cells; Reactive oxygen species; Transcriptional factors

Indexed keywords

CYTOKINE; HYDROGEN PEROXIDE; INTERLEUKIN 10; INTERLEUKIN 18; INTERLEUKIN 1BETA; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; SERUM RESPONSE FACTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOKINE RELEASE; EMBRYO; EMBRYOID BODY; EMBRYONIC STEM CELL; GENE EXPRESSION; HEART INFARCTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

CARDIAC DIFFERENTIATION; CYTOKINES; EMBRYONIC STEM CELLS; REACTIVE OXYGEN SPECIES; TRANSCRIPTIONAL FACTORS;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; CYTOKINES; EMBRYONIC STEM CELLS; INFLAMMATION MEDIATORS; MICE; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; REACTIVE OXYGEN SPECIES; TRANSCRIPTION FACTORS;

EID: 84886256432     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2013.04.178     Document Type: Article

References (68)

1. J.A. Thomson, J. Itskovitz-Eldor, and S.S. Shapiro Embryonic stem cell lines derived from human blastocysts Science 282 1998 1145 1147
2. T. Xue, H.C. Cho, and F.G. Akar Functional integration of electrically active cardiac derivatives from genetically engineered human embryonic stem cells with quiescent recipient ventricular cardiomyocytes: insights into the development of cell-based pacemakers Circulation 111 2005 11 20
3. M.A. Laflamme, K.Y. Chen, and A.V. Naumova Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts Nat Biotechnol 25 2007 1015 1024
4. Y. Yeghiazarians, M. Gaur, and Y. Zhang Myocardial improvement with human embryonic stem cell-derived cardiomyocytes enriched by p38MAPK inhibition Cytotherapy 14 2012 223 231
5. O. Caspi, I. Huber, and I. Kehat Transplantation of human embryonic stem cell-derived cardiomyocytes improves myocardial performance in infarcted rat hearts J Am Coll Cardiol 50 2007 1884 1893
6. L.W. van Laake, R. Passier, and J. Monshouwer-Kloots Human embryonic stem cell-derived cardiomyocytes survive and mature in the mouse heart and transiently improve function after myocardial infarction Stem Cell Res 1 2007 9 24
7. J. Li, M. Stouffs, and L. Serrander The NADPH oxidase NOX4 drives cardiac differentiation: role in regulating cardiac transcription factors and MAP kinase activation Mol Biol Cell 17 2006 3978 3988
8. M. Schmelter, B. Ateghang, S. Helmig, M. Wartenberg, and H. Sauer Embryonic stem cells utilize reactive oxygen species as transducers of mechanical strain-induced cardiovascular differentiation FASEB J 20 2006 1182 1184
9. H. Sauer, G. Rahimi, J. Hescheler, and M. Wartenberg Role of reactive oxygen species and phosphatidylinositol 3-kinase in cardiomyocyte differentiation of embryonic stem cells FEBS Lett 476 2000 218 223
10. F. Kosar, Y. Aksoy, G. Ozguntekin, I. Ozerol, and E. Varol Relationship between cytokines and tumour markers in patients with chronic heart failure Eur J Heart Fail 8 2006 270 274
11. A. Herskowitz, S. Choi, A.A. Ansari, and S. Wesselingh Cytokine mRNA expression in postischemic/reperfused myocardium Am J Pathol 146 1995 419 428
12. S.E. Francis, H. Holden, C.M. Holt, and G.W. Duff Interleukin-1 in myocardium and coronary arteries of patients with dilated cardiomyopathy J Mol Cell Cardiol 30 1998 215 223
13. F.J. Neumann, I. Ott, and M. Gawaz Cardiac release of cytokines and inflammatory responses in acute myocardial infarction Circulation 92 1995 748 755
14. K. Ono, A. Matsumori, T. Shioi, Y. Furukawa, and S. Sasayama Cytokine gene expression after myocardial infarction in rat hearts: possible implication in left ventricular remodeling Circulation 98 1998 149 156
15. H.K. Yip, A.A. Youssef, and L.T. Chang Association of interleukin-10 level with increased 30-day mortality in patients with ST-segment elevation acute myocardial infarction undergoing primary coronary intervention Circ J 71 2007 1086 1091
16. B.J. Pomerantz, L.L. Reznikov, A.H. Harken, and C.A. Dinarello Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1beta Proc Natl Acad Sci U S A 98 2001 2871 2876
17. A. Behfar, C. Perez-Terzic, and R.S. Faustino Cardiopoietic programming of embryonic stem cells for tumor-free heart repair J Exp Med 204 2007 405 420
18. S. Malek, E. Kaplan, and J.F. Wang Successful implantation of intravenously administered stem cells correlates with severity of inflammation in murine myocarditis Pflugers Arch 452 2006 268 275
19. J.Y. Min, X. Huang, and M. Xiang Homing of intravenously infused embryonic stem cell-derived cells to injured hearts after myocardial infarction J Thorac Cardiovasc Surg 131 2006 889 897
20. Y. Chen, Q. Ke, and Y. Yang Cardiomyocytes overexpressing TNF-alpha attract migration of embryonic stem cells via activation of p38 and c-Jun amino-terminal kinase FASEB J 17 2003 2231 2239
21. H. Ebelt, M. Jungblut, and Y. Zhang Cellular cardiomyoplasty: improvement of left ventricular function correlates with the release of cardioactive cytokines Stem Cells 25 2007 236 244
22. M. Nakano, A.A. Knowlton, Z. Dibbs, and D.L. Mann Tumor necrosis factor-alpha confers resistance to hypoxic injury in the adult mammalian cardiac myocyte Circulation 97 1998 1392 1400
23. N. Lopez, J. Diez, and M.A. Fortuno Characterization of the protective effects of cardiotrophin-1 against non-ischemic death stimuli in adult cardiomyocytes Cytokine 30 2005 282 292
24. T. Yokoyama, M. Nakano, J.L. Bednarczyk, B.W. McIntyre, M. Entman, and D.L. Mann Tumor necrosis factor-alpha provokes a hypertrophic growth response in adult cardiac myocytes Circulation 95 1997 1247 1252
25. T. Yokoyama, L. Vaca, R.D. Rossen, W. Durante, P. Hazarika, and D.L. Mann Cellular basis for the negative inotropic effects of tumor necrosis factor-alpha in the adult mammalian heart J Clin Invest 92 1993 2303 2312
26. T. Gulick, M.K. Chung, S.J. Pieper, L.G. Lange, and G.F. Schreiner Interleukin 1 and tumor necrosis factor inhibit cardiac myocyte beta-adrenergic responsiveness Proc Natl Acad Sci U S A 86 1989 6753 6757
27. S.Y. Tsang, J.C. Moore, R.V. Huizen, C.W. Chan, and R.A. Li Ectopic expression of systemic RNA interference defective protein in embryonic stem cells Biochem Biophys Res Commun 357 2007 480 486
28. S.Y. Ng, C.H. Chin, and Y.T. Lau Role of voltage-gated potassium channels in the fate determination of embryonic stem cells J Cell Physiol 224 2010 165 177
29. Y.T. Lau, C.K. Wong, and J. Luo Effects of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers on the proliferation and cell cycle progression of embryonic stem cells Pflugers Arch 461 2011 191 202
30. C.K. Wong, W.Y. So, and S.K. Law Estrogen controls embryonic stem cell proliferation via store-operated calcium entry & the nuclear factor of activated T-cells (NFAT) J Cell Physiol 227 2012 2519 2530
31. J.C. Moore, S.Y. Tsang, and S.N. Rushing Functional consequences of overexpressing the gap junction Cx43 in the cardiogenic potential of pluripotent human embryonic stem cells Biochem Biophys Res Commun 377 2008 46 51
32. K.R. Boheler, J. Czyz, D. Tweedie, H.T. Yang, S.V. Anisimov, and A.M. Wobus Differentiation of pluripotent embryonic stem cells into cardiomyocytes Circ Res 91 2002 189 201
33. P.R. Kemp, and J.C. Metcalfe Four isoforms of serum response factor that increase or inhibit smooth-muscle-specific promoter activity Biochem J 345 Pt 3 2000 445 451
34. J. Savickiene AP, G. Treigyte, and R. Navakauskiene AP-1 binding activity is modulated by post-translational modifications during granulocytic differentiation of HL-60 cells Biologija 3 2003 10 12
35. R. Janknecht, R.A. Hipskind, T. Houthaeve, A. Nordheim, and H.G. Stunnenberg Identification of multiple SRF N-terminal phosphorylation sites affecting DNA binding properties EMBO J 11 1992 1045 1054
36. R.P. Misra, V.M. Rivera, J.M. Wang, P.D. Fan, and M.E. Greenberg The serum response factor is extensively modified by phosphorylation following its synthesis in serum-stimulated fibroblasts Mol Cell Biol 11 1991 4545 4554
37. H. Sauer, G. Rahimi, J. Hescheler, and M. Wartenberg Effects of electrical fields on cardiomyocyte differentiation of embryonic stem cells J Cell Biochem 75 1999 710 723
38. J.Q. He, Y. Ma, Y. Lee, J.A. Thomson, and T.J. Kamp Human embryonic stem cells develop into multiple types of cardiac myocytes: action potential characterization Circ Res 93 2003 32 39
39. A. Bondue, S. Tannler, and G. Chiapparo Defining the earliest step of cardiovascular progenitor specification during embryonic stem cell differentiation J Cell Biol 192 2011 751 765
40. D.L. Hare, and M. Silverton Recovery from acute coronary syndromes. Hidden snares to resuming normality Aust Fam Physician 30 2001 959 963
41. K. Kuwahara, Y. Saito, and M. Takano NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function EMBO J 22 2003 6310 6321
42. M. Kawana, M.E. Lee, E.E. Quertermous, and T. Quertermous Cooperative interaction of GATA-2 and AP1 regulates transcription of the endothelin-1 gene Mol Cell Biol 15 1995 4225 4231
43. M. Seyed, and J.X. Dimario Sp1 is required for transcriptional activation of the fibroblast growth factor receptor 1 gene in neonatal cardiomyocytes Gene 400 2007 150 157
44. Z. Niu, W. Yu, and S.X. Zhang Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets J Biol Chem 280 2005 32531 32538
45. A.D. Mori, Y. Zhu, and I. Vahora Tbx5-dependent rheostatic control of cardiac gene expression and morphogenesis Dev Biol 297 2006 566 586
46. D. Yelon, B. Ticho, and M.E. Halpern The bHLH transcription factor hand2 plays parallel roles in zebrafish heart and pectoral fin development Development 127 2000 2573 2582
47. M. Tanaka, S.B. Wechsler, I.W. Lee, N. Yamasaki, J.A. Lawitts, and S. Izumo Complex modular cis-acting elements regulate expression of the cardiac specifying homeobox gene Csx/Nkx2.5 Development 126 1999 1439 1450
48. P.K. Bhavsar, K.A. Dellow, M.H. Yacoub, N.J. Brand, and P.J. Barton Identification of cis-acting DNA elements required for expression of the human cardiac troponin I gene promoter J Mol Cell Cardiol 32 2000 95 108
49. A.J. Watt, M.A. Battle, J. Li, and S.A. Duncan GATA4 is essential for formation of the proepicardium and regulates cardiogenesis Proc Natl Acad Sci U S A 101 2004 12573 12578
50. T.S.M. Bahorun, V. Luximon-Ramma, and O.I. Aruoma Free radicals and antioxidants in cardiovascular health and disease Internet J Med 1 Jul-Dec 2006 25 41 [Update]
51. F.L. Crespo, V.R. Sobrado, L. Gomez, A.M. Cervera, and K.J. McCreath Mitochondrial reactive oxygen species mediate cardiomyocyte formation from embryonic stem cells in high glucose Stem Cells 28 2010 1132 1142
52. L. Ding, X.G. Liang, Y. Hu, D.Y. Zhu, and Y.J. Lou Involvement of p38MAPK and reactive oxygen species in icariin-induced cardiomyocyte differentiation of murine embryonic stem cells in vitro Stem Cells Dev 17 2008 751 760
53. D. Srivastava, P. Cserjesi, and E.N. Olson A subclass of bHLH proteins required for cardiac morphogenesis Science 270 1995 1995 1999
54. Z. Niu, D. Iyer, and S.J. Conway Serum response factor orchestrates nascent sarcomerogenesis and silences the biomineralization gene program in the heart Proc Natl Acad Sci U S A 105 2008 17824 17829
55. N.G. Frangogiannis Targeting the inflammatory response in healing myocardial infarcts Curr Med Chem 13 2006 1877 1893
56. M. Bujak, M. Dobaczewski, and K. Chatila Interleukin-1 receptor type I signaling critically regulates infarct healing and cardiac remodeling Am J Pathol 173 2008 57 67
57. C. Bao, J. Guo, G. Lin, M. Hu, and Z. Hu TNFR gene-modified mesenchymal stem cells attenuate inflammation and cardiac dysfunction following MI Scand Cardiovasc J 42 2008 56 62
58. T. Kanda, and T. Takahashi Interleukin-6 and cardiovascular diseases Jpn Heart J 45 2004 183 193
59. A.A. Youssef, L.T. Chang, and C.L. Hang Level and value of interleukin-18 in patients with acute myocardial infarction undergoing primary coronary angioplasty Circ J 71 2007 703 708
60. K.G. Birukov Cyclic stretch, reactive oxygen species, and vascular remodeling Antioxid Redox Signal 11 2009 1651 1667
61. H. Sauer, W. Neukirchen, G. Rahimi, F. Grunheck, J. Hescheler, and M. Wartenberg Involvement of reactive oxygen species in cardiotrophin-1-induced proliferation of cardiomyocytes differentiated from murine embryonic stem cells Exp Cell Res 294 2004 313 324
62. H. Qiao, H. Zhang, and S. Yamanaka Long-term improvement in postinfarct left ventricular global and regional contractile function is mediated by embryonic stem cell-derived cardiomyocytes Circ Cardiovasc Imaging 4 2011 33 41
63. K. Matsuura, A. Honda, and T. Nagai Transplantation of cardiac progenitor cells ameliorates cardiac dysfunction after myocardial infarction in mice J Clin Invest 119 2009 2204 2217
64. N. Christoforou, B.N. Oskouei, and P. Esteso Implantation of mouse embryonic stem cell-derived cardiac progenitor cells preserves function of infarcted murine hearts PLoS One 5 2010 e11536
65. J.Y. Min, Y. Yang, and K.L. Converso Transplantation of embryonic stem cells improves cardiac function in postinfarcted rats J Appl Physiol 92 2002 288 296
66. S.Y. Liao, Y. Liu, and C.W. Siu Proarrhythmic risk of embryonic stem cell-derived cardiomyocyte transplantation in infarcted myocardium Heart Rhythm 7 2010 1852 1859
67. H. Hentze, P.L. Soong, S.T. Wang, B.W. Phillips, T.C. Putti, and N.R. Dunn Teratoma formation by human embryonic stem cells: evaluation of essential parameters for future safety studies Stem Cell Res 2 2009 198 210
68. Q. Lin, Q. Fu, and Y. Zhang Tumourigenesis in the infarcted rat heart is eliminated through differentiation and enrichment of the transplanted embryonic stem cells Eur J Heart Fail 12 2010 1179 1185