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Although excess use of TMSOTf could afford 4 at -90 C in 99% yield, the consumption of starting material was irreproducible.
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Although excess use of TMSOTf could afford 4 at -90 C in 99% yield, the consumption of starting material was irreproducible.
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Triazolylalkanol by [3 + 2] (no Friedel-Crafts reaction) was not observed.
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Triazolylalkanol by [3 + 2] (no Friedel-Crafts reaction) was not observed.
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The regiochemistry of the resulting triazoles were determined by NOEs and/or X-ray crystallographic analyses. CIF files of triazoles 2b, 2h, 2j, 2q, 2s, 4, and 7d (CCDC 950501-950506 and 956342) are available free of charge from The Cambridge Crystallographic Data Centre via.
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The regiochemistry of the resulting triazoles were determined by NOEs and/or X-ray crystallographic analyses. CIF files of triazoles 2b, 2h, 2j, 2q, 2s, 4, and 7d (CCDC 950501-950506 and 956342) are available free of charge from The Cambridge Crystallographic Data Centre via www.ccdc.cam.ac.uk/data-request/ cif.
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