Exendin-4 Protects Mitochondria from Reactive Oxygen Species Induced Apoptosis in Pancreatic Beta Cells

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Li, Zhen ^a   Zhou, Zhiguang ^a   Huang, Gan ^a   Hu, Fang ^a   Xiang, Yufei ^a   He, Lining ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM INDEPENDENT PHOSPHOLIPASE A2; CASPASE 3; CASPASE 8; CYTOCHROME C; EXENDIN 4; HYDROGEN PEROXIDE; MITOCHONDRIAL PROTEIN; PROTEIN DLAMO; REACTIVE OXYGEN METABOLITE; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; TERT BUTYL HYDROPEROXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL LINE; CELL PROTECTION; CONTROLLED STUDY; DNA DEGRADATION; ENZYME ACTIVITY; GLUCOTOXICITY; IN VITRO STUDY; LIPID OXIDATION; LIPOTOXICITY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL TUMOR; PROTEIN EXPRESSION; PROTEIN SECRETION;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASE 3; CELL LINE; DNA FRAGMENTATION; ENZYME ACTIVATION; FATTY ACIDS; GENE EXPRESSION REGULATION; GROUP VI PHOSPHOLIPASES A2; HYPOGLYCEMIC AGENTS; INSULIN-SECRETING CELLS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOCHONDRIA; OXIDATIVE STRESS; PEPTIDES; PHOSPHOLIPASES A2, CYTOSOLIC; REACTIVE OXYGEN SPECIES; TIME FACTORS; TRANSCRIPTION, GENETIC; VENOMS;

EID: 84886242581     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0076172     Document Type: Article

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