메뉴 건너뛰기




Volumn 17, Issue 4, 2013, Pages 370-377

Expression of CTLA-4 and Foxp3 in peripheral blood T cells of patients with squamous cell laryngeal carcinoma

Author keywords

CTLA 4 (CD152); Foxp3; Laryngeal carcinoma; Mode and depth of invasion; Peripheral blood T cells

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; MESSENGER RNA; TRANSCRIPTION FACTOR FOXP3;

EID: 84886054768     PISSN: 14282526     EISSN: None     Source Type: Journal    
DOI: 10.5114/wo.2013.37219     Document Type: Article
Times cited : (7)

References (40)
  • 2
    • 84869443740 scopus 로고    scopus 로고
    • Functional tumor infiltrating TH1 and TH2 effectors in large early-stage cervical cancer are suppressed by regulatory T cells
    • Adurthi S, Mukherjee G, Krishnamurthy H, Sudhir K, Bafna UD, Umadevi K, Jayshree RS. Functional tumor infiltrating TH1 and TH2 effectors in large early-stage cervical cancer are suppressed by regulatory T cells. Int J Gynecol Cancer 2012; 22: 1130-7.
    • (2012) Int J Gynecol Cancer , vol.22 , pp. 1130-1137
    • Adurthi, S.1    Mukherjee, G.2    Krishnamurthy, H.3    Sudhir, K.4    Bafna, U.D.5    Umadevi, K.6    Jayshree, R.S.7
  • 3
    • 84863087679 scopus 로고    scopus 로고
    • Hepatocellular carcinoma and macrophage interaction induced tumor immunosuppression via Treg requires TLR4 signaling
    • Yang J, Zhang JX, Wang H, Wang GL, Hu QG, Zheng QC. Hepatocellular carcinoma and macrophage interaction induced tumor immunosuppression via Treg requires TLR4 signaling. World J Gastroenterol 2012; 18: 2938-47.
    • (2012) World J Gastroenterol , vol.18 , pp. 2938-2947
    • Yang, J.1    Zhang, J.X.2    Wang, H.3    Wang, G.L.4    Hu, Q.G.5    Zheng, Q.C.6
  • 4
    • 79959605064 scopus 로고    scopus 로고
    • Increased frequency of CD4+ CD25(high)FoxP3+ regulatory T cells in patients with hepatocellular carcinoma
    • Feng X, Li B, Ye H, Long D. Increased frequency of CD4+ CD25(high)FoxP3+ regulatory T cells in patients with hepatocellular carcinoma. Arch Immunol Ther Exp 2011; 59: 309-14.
    • (2011) Arch Immunol Ther Exp , vol.59 , pp. 309-314
    • Feng, X.1    Li, B.2    Ye, H.3    Long, D.4
  • 5
    • 78149411580 scopus 로고    scopus 로고
    • Increased CTLA-4 and FOXP3 transcripts in peripheral blood mononuclear cells of patients with breast cancer
    • Jaberipour M, Habibagahi M, Hosseini A, Habibabad SR, Talei A, Ghaderi A. Increased CTLA-4 and FOXP3 transcripts in peripheral blood mononuclear cells of patients with breast cancer. Pathol Oncol Res 2010; 16: 547-51.
    • (2010) Pathol Oncol Res , vol.16 , pp. 547-551
    • Jaberipour, M.1    Habibagahi, M.2    Hosseini, A.3    Habibabad, S.R.4    Talei, A.5    Ghaderi, A.6
  • 6
    • 77949425341 scopus 로고    scopus 로고
    • Regulatory T cells and immune tolerance to tumors
    • Cao X. Regulatory T cells and immune tolerance to tumors. Immunol Res 2010; 46: 79-93.
    • (2010) Immunol Res , vol.46 , pp. 79-93
    • Cao, X.1
  • 8
    • 68449099413 scopus 로고    scopus 로고
    • Regulatory T cells: Major players in the tumor microenvironment
    • Beyer M, Schultze JL. Regulatory T cells: major players in the tumor microenvironment. Curr Pharm Des 2009; 15: 1879-92.
    • (2009) Curr Pharm des , vol.15 , pp. 1879-1892
    • Beyer, M.1    Schultze, J.L.2
  • 9
    • 77951641002 scopus 로고    scopus 로고
    • Significance of immunoregulatory T cells in different stages of breast cancer patients
    • Abo-Elenein A, Elgohary SE, Hashish A, El-Halaby E. Significance of immunoregulatory T cells in different stages of breast cancer patients. Egypt J Immunol 2008; 15: 145-52.
    • (2008) Egypt J Immunol , vol.15 , pp. 145-152
    • Abo-Elenein, A.1    Elgohary, S.E.2    Hashish, A.3    El-Halaby, E.4
  • 10
    • 52449125138 scopus 로고    scopus 로고
    • T regulatory type 1 cells in squamous cell carcinoma of the head and neck: Mechanisms of suppression and expansion in advanced disease
    • Bergmann C, Strauss L, Wang Y, Szczepanski MJ, Lang S, Johnson JT, Whiteside TL. T regulatory type 1 cells in squamous cell carcinoma of the head and neck: mechanisms of suppression and expansion in advanced disease. Clin Cancer Res 2008; 14: 3706-15.
    • (2008) Clin Cancer Res , vol.14 , pp. 3706-3715
    • Bergmann, C.1    Strauss, L.2    Wang, Y.3    Szczepanski, M.J.4    Lang, S.5    Johnson, J.T.6    Whiteside, T.L.7
  • 11
    • 35648983897 scopus 로고    scopus 로고
    • + Treg clones obtained from peripheral blood of patients with cancer
    • DOI 10.1002/ijc.23001
    • Strauss L, Bergmann C, Whiteside TL. Functional and phenotypic characteristics of CD4+CD25highFoxp3+ Treg clones obtained from peripheral blood of patients with cancer. Int J Cancer 2007; 121: 2473-83. (Pubitemid 350022417)
    • (2007) International Journal of Cancer , vol.121 , Issue.11 , pp. 2473-2483
    • Strauss, L.1    Bergmann, C.2    Whiteside, T.L.3
  • 12
    • 34547655923 scopus 로고    scopus 로고
    • + T cells secreting interleukin-10 and transforming growth factor-β1 mediates suppression in the tumor microenvironment
    • DOI 10.1158/1078-0432.CCR-07-0472
    • Strauss L, Bergmann C, Szczepanski M, Gooding W, Johnson JT, Whiteside TL. A unique subset of CD4+CD25highFoxp3+ T cells secreting interleukin-10 and transforming growth factor-beta1 mediates suppression in the tumor microenvironment. Clin Cancer Res 2007; 13: 4345-54. (Pubitemid 47219698)
    • (2007) Clinical Cancer Research , vol.13 , Issue.15 , pp. 4345-4354
    • Strauss, L.1    Bergmann, C.2    Szczepanski, M.3    Gooding, W.4    Johnson, J.T.5    Whiteside, T.L.6
  • 13
    • 35948952840 scopus 로고    scopus 로고
    • + T cells in the circulation of patients with squamous cell carcinoma of the head and neck
    • DOI 10.1158/1078-0432.CCR-07-1403
    • Strauss L, Bergmann C, Gooding W, Johnson JT, Whiteside TL. The frequency and suppressor function of CD4+CD25highFoxp3+ T cells in the circulation of patients with squamous cell carcinoma of the head and neck. Clin Cancer Res 2007; 13: 6301-11. (Pubitemid 350075018)
    • (2007) Clinical Cancer Research , vol.13 , Issue.21 , pp. 6301-6311
    • Strauss, L.1    Bergmann, C.2    Gooding, W.3    Johnson, J.T.4    Whiteside, T.L.5
  • 14
    • 38449110163 scopus 로고    scopus 로고
    • The characterization and role of regulatory T cells in immune reactions
    • DOI 10.2741/2840
    • Wilczynski JR, Radwan M, Kalinka J. The characterization and role of regulatory T cells in immune reactions. Front Biosci 2008; 13: 2266-74. (Pubitemid 351589251)
    • (2008) Frontiers in Bioscience , vol.13 , Issue.6 , pp. 2266-2274
    • Wilczynski, J.R.1    Radwan, M.2    Kalinka, J.3
  • 15
    • 84870050796 scopus 로고    scopus 로고
    • Skewed immunological balance between Th17 (CD4(+)IL17A (+)) and Treg (CD4 (+)CD25 (+)FOXP3 (+)) cells in human oral squamous cell carcinoma
    • Gaur P, Qadir GA, Upadhyay S, Singh AK, Shukla NK, Das SN. Skewed immunological balance between Th17 (CD4(+)IL17A (+)) and Treg (CD4 (+)CD25 (+)FOXP3 (+)) cells in human oral squamous cell carcinoma. Cell Oncol (Dordr) 2012; 35: 335-43.
    • (2012) Cell Oncol (Dordr) , vol.35 , pp. 335-343
    • Gaur, P.1    Qadir, G.A.2    Upadhyay, S.3    Singh, A.K.4    Shukla, N.K.5    Das, S.N.6
  • 17
    • 77449101222 scopus 로고    scopus 로고
    • Homeostasis of peripheral FoxP3(+) CD4 (+) regulatory T cells in patients with early and late stage breast cancer
    • Rech AJ, Mick R, Kaplan DE, Chang KM, Domchek SM, Vonderheide RH. Homeostasis of peripheral FoxP3(+) CD4 (+) regulatory T cells in patients with early and late stage breast cancer. Cancer Immunol Immunother 2010; 59: 599-607.
    • (2010) Cancer Immunol Immunother , vol.59 , pp. 599-607
    • Rech, A.J.1    Mick, R.2    Kaplan, D.E.3    Chang, K.M.4    Domchek, S.M.5    Vonderheide, R.H.6
  • 18
    • 80053925077 scopus 로고    scopus 로고
    • Expansion of peripheral and intratumoral regulatory T-cells in hepatocellular carcinoma: A case-control study
    • Thakur S, Singla A, Chawla Y, Rajwanshi A, Kalra N, Arora SK. Expansion of peripheral and intratumoral regulatory T-cells in hepatocellular carcinoma: a case-control study. Indian J Pathol Microbiol 2011; 54: 448-53.
    • (2011) Indian J Pathol Microbiol , vol.54 , pp. 448-453
    • Thakur, S.1    Singla, A.2    Chawla, Y.3    Rajwanshi, A.4    Kalra, N.5    Arora, S.K.6
  • 19
    • 77957607351 scopus 로고    scopus 로고
    • Increased prevalence of regulatory T cells in the tumor microenvironment and its correlation with TNM stage of hepatocellular carcinoma
    • Shen X, Li N, Li H, Zhang T, Wang F, Li Q. Increased prevalence of regulatory T cells in the tumor microenvironment and its correlation with TNM stage of hepatocellular carcinoma. J Cancer Res Clin Oncol 2010; 136: 1745-54.
    • (2010) J Cancer Res Clin Oncol , vol.136 , pp. 1745-1754
    • Shen, X.1    Li, N.2    Li, H.3    Zhang, T.4    Wang, F.5    Li, Q.6
  • 20
    • 84863911981 scopus 로고    scopus 로고
    • Foxp3 expression is associated with aggressiveness in differentiated thyroid carcinomas
    • Cunha LL, Morari EC, Nonogaki S, Soares FA, Vassallo J, Ward LS. Foxp3 expression is associated with aggressiveness in differentiated thyroid carcinomas. Clinics 2012; 67: 483-8.
    • (2012) Clinics , vol.67 , pp. 483-488
    • Cunha, L.L.1    Morari, E.C.2    Nonogaki, S.3    Soares, F.A.4    Vassallo, J.5    Ward, L.S.6
  • 21
    • 84871684240 scopus 로고    scopus 로고
    • Presence of tumour-infiltrating FOXP3+ lymphocytes correlates with immature tumour angiogenesis in renal cell carcinomas
    • Zhan HL, Gao X, Zhou XF, Pu XY, Wang DJ. Presence of tumour-infiltrating FOXP3+ lymphocytes correlates with immature tumour angiogenesis in renal cell carcinomas. Asian Pac J Cancer Prev 2012; 13: 867-72.
    • (2012) Asian Pac J Cancer Prev , vol.13 , pp. 867-872
    • Zhan, H.L.1    Gao, X.2    Zhou, X.F.3    Pu, X.Y.4    Wang, D.J.5
  • 22
    • 84860766933 scopus 로고    scopus 로고
    • Expression of Forkhead box P3 in tumour cells causes immunoregulatory function of signet ring cell carcinoma of the stomach
    • Yoshii M, Tanaka H, Ohira M, et al. Expression of Forkhead box P3 in tumour cells causes immunoregulatory function of signet ring cell carcinoma of the stomach. Br J Cancer 2012; 106: 1668-74.
    • (2012) Br J Cancer , vol.106 , pp. 1668-1674
    • Yoshii, M.1    Tanaka, H.2    Ohira, M.3
  • 23
    • 78650611297 scopus 로고    scopus 로고
    • Correlation between elevated FOXP3 expression and increased lymph node metastasis of gastric cancer
    • Wang LH, Su L, Wang JT. Correlation between elevated FOXP3 expression and increased lymph node metastasis of gastric cancer. Chin Med J (Engl) 2010; 123: 3545-9.
    • (2010) Chin Med J (Engl) , vol.123 , pp. 3545-3549
    • Wang, L.H.1    Su, L.2    Wang, J.T.3
  • 24
    • 76049117928 scopus 로고    scopus 로고
    • Elevated expression of Foxp3 in tumorinfiltrating Treg cells suppresses T-cell proliferation and contributes to gastric cancer progression in a COX-2-dependent manner
    • Yuan XL, Chen L, Li MX, et al. Elevated expression of Foxp3 in tumorinfiltrating Treg cells suppresses T-cell proliferation and contributes to gastric cancer progression in a COX-2-dependent manner. Clin Immunol 2010; 134: 277-88.
    • (2010) Clin Immunol , vol.134 , pp. 277-288
    • Yuan, X.L.1    Chen, L.2    Li, M.X.3
  • 25
    • 84863783251 scopus 로고    scopus 로고
    • Increase of regulatory T cells in metastatic stage and CTLA-4 over expression in lymphocytes of patients with nonsmall cell lung cancer (NSCLC)
    • Erfani N, Mehrabadi SM, Ghayumi MA, Haghshenas MR, Mojtahedi Z, Ghaderi A, Amani D. Increase of regulatory T cells in metastatic stage and CTLA-4 over expression in lymphocytes of patients with nonsmall cell lung cancer (NSCLC). Lung Cancer 2012; 77: 306-11.
    • (2012) Lung Cancer , vol.77 , pp. 306-311
    • Erfani, N.1    Mehrabadi, S.M.2    Ghayumi, M.A.3    Haghshenas, M.R.4    Mojtahedi, Z.5    Ghaderi, A.6    Amani, D.7
  • 26
    • 69249229779 scopus 로고    scopus 로고
    • CD13+CD4+CD25hi regulatory T cells exhibit higher suppressive function and increase with tumor stage in nonsmall cell lung cancer patients
    • Ju S, Qiu H, Zhou X, et al. CD13+CD4+CD25hi regulatory T cells exhibit higher suppressive function and increase with tumor stage in nonsmall cell lung cancer patients. Cell Cycle 2009; 8: 2578-85.
    • (2009) Cell Cycle , vol.8 , pp. 2578-2585
    • Ju, S.1    Qiu, H.2    Zhou, X.3
  • 27
    • 84856471270 scopus 로고    scopus 로고
    • Accumulation of CCR4+CTLA-4 FOXP3+CD25(hi) regulatory T cells in colon adenocarcinomas correlate to reduced activation of conventional T cells
    • Svensson H, Olofsson V, Lundin S, Yakkala C, Björck S, Börjesson L, Gustavsson B, Quiding-Järbrink M. Accumulation of CCR4+CTLA-4 FOXP3+CD25(hi) regulatory T cells in colon adenocarcinomas correlate to reduced activation of conventional T cells. PLoS One 2012; 7: e30695.
    • (2012) PLoS One , vol.7
    • Svensson, H.1    Olofsson, V.2    Lundin, S.3    Yakkala, C.4    Björck, S.5    Börjesson, L.6    Gustavsson, B.7    Quiding-Järbrink, M.8
  • 28
    • 84863437838 scopus 로고    scopus 로고
    • Dysregulated expression of both the costimulatory CD28 and inhibitory CTLA-4 molecules in PB T cells of advanced cervical cancer patients suggests systemic immunosuppression related to disease progression
    • Kosmaczewska A, Bocko D, Ciszak L, Wlodarska-Polinska I, Kornafel J, Szteblich A, Masternak A, Frydecka I. Dysregulated expression of both the costimulatory CD28 and inhibitory CTLA-4 molecules in PB T cells of advanced cervical cancer patients suggests systemic immunosuppression related to disease progression. Pathol Oncol Res 2012; 18: 479-89.
    • (2012) Pathol Oncol Res , vol.18 , pp. 479-489
    • Kosmaczewska, A.1    Bocko, D.2    Ciszak, L.3    Wlodarska-Polinska, I.4    Kornafel, J.5    Szteblich, A.6    Masternak, A.7    Frydecka, I.8
  • 29
    • 36048939615 scopus 로고    scopus 로고
    • Association of CTLA-4 gene polymorphisms with sporadic breast cancer in Chinese Han population
    • Wang L, Li D, Fu Z, Li H, Jiang W, Li D. Association of CTLA-4 gene polymorphisms with sporadic breast cancer in Chinese Han population. BMC Cancer 2007; 7: 173-6.
    • (2007) BMC Cancer , vol.7 , pp. 173-176
    • Wang, L.1    Li, D.2    Fu, Z.3    Li, H.4    Jiang, W.5    Li, D.6
  • 30
    • 84867791009 scopus 로고    scopus 로고
    • Strong Association of CTLA-4 Variation (CT60A/G) and CTLA-4 Haplotypes with Predisposition of Iranians to Head and Neck Cancer
    • Erfani N, Haghshenas MR, Hoseini MA, Hashemi SB, Khademi B, Ghaderi A. Strong Association of CTLA-4 Variation (CT60A/G) and CTLA-4 Haplotypes with Predisposition of Iranians to Head and Neck Cancer. Iran J Immunol 2012; 9: 188-98.
    • (2012) Iran J Immunol , vol.9 , pp. 188-198
    • Erfani, N.1    Haghshenas, M.R.2    Hoseini, M.A.3    Hashemi, S.B.4    Khademi, B.5    Ghaderi, A.6
  • 31
    • 84866694932 scopus 로고    scopus 로고
    • CD4+CD25+ Treg derived from hepatocellular carcinoma mice inhibits tumor immunity
    • Chen X, Du Y, Huang Z. CD4+CD25+ Treg derived from hepatocellular carcinoma mice inhibits tumor immunity. Immunol Lett 2012; 148: 83-9.
    • (2012) Immunol Lett , vol.148 , pp. 83-89
    • Chen, X.1    Du, Y.2    Huang, Z.3
  • 32
    • 58149114537 scopus 로고    scopus 로고
    • Clinical significance of the proportion of CD4+CD25+ regulatory T cells in peripheral blood of hepatocellular carcinoma patients: A report of 117 cases
    • Peng QQ, Li SP, Xu L, Li JQ. Clinical significance of the proportion of CD4+CD25+ regulatory T cells in peripheral blood of hepatocellular carcinoma patients: a report of 117 cases. Ai Zheng 2007; 26: 748- 51.
    • (2007) Ai Zheng , vol.26 , pp. 748-751
    • Peng, Q.Q.1    Li, S.P.2    Xu, L.3    Li, J.Q.4
  • 34
    • 77956637830 scopus 로고    scopus 로고
    • Circulating soluble CTLA4 (sCTLA4) is elevated in patients with breast cancer
    • Erfani N, Razmkhah M, Ghaderi A. Circulating soluble CTLA4 (sCTLA4) is elevated in patients with breast cancer. Cancer Invest 2010; 28: 828-32.
    • (2010) Cancer Invest , vol.28 , pp. 828-832
    • Erfani, N.1    Razmkhah, M.2    Ghaderi, A.3
  • 35
    • 84867154990 scopus 로고    scopus 로고
    • Cancer immunotherapy - novel perspectives
    • Rothschild S, Zippelius A. Cancer immunotherapy - novel perspectives. Ther Umsch 2012; 69: 559-63.
    • (2012) Ther Umsch , vol.69 , pp. 559-563
    • Rothschild, S.1    Zippelius, A.2
  • 36
    • 0141790076 scopus 로고    scopus 로고
    • New TNM staging criteria for head and neck tumors
    • DOI 10.1002/ssu.10019
    • O'Sullivan B, Shah J. New TNM staging criteria for head and neck tumors. Semin Surg Oncol 2003; 21: 30-42. (Pubitemid 37127472)
    • (2003) Seminars in Surgical Oncology , vol.21 , Issue.1 , pp. 30-42
    • O'Sullivan, B.1    Shah, J.2
  • 37
    • 34347403941 scopus 로고    scopus 로고
    • Tumor front grading in prediction of survival and lymph node metastases in patients with laryngeal carcinoma
    • Starska K, Kulig A, Lukomski M. Tumor front grading in prediction of survival and lymph node metastases in patients with laryngeal carcinoma. Adv Med Sci 2006; 51: 200-4.
    • (2006) Adv Med Sci , vol.51 , pp. 200-204
    • Starska, K.1    Kulig, A.2    Lukomski, M.3
  • 38
    • 0018363158 scopus 로고
    • Determination of protein by a modified Lowry procedure in the presence of some commonly used detergents
    • DOI 10.1016/0003-2697(79)90548-7
    • Cadman E, Bostwick JR, Eichberg J. Determination of protein by a modified Lowry procedure in the presence of some commonly used detergents. Anal Biochem 1979; 96: 21-3. (Pubitemid 9196886)
    • (1979) Analytical Biochemistry , vol.96 , Issue.1 , pp. 21-23
    • Cadman, E.1    Bostwick, J.R.2    Eichberg, J.3
  • 39
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680-5.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 40
    • 0025274731 scopus 로고
    • Important parameters in semi-dry electrophoretic transfer
    • Jacobson G, Kårsnäs P. Important parameters in semi-dry electrophoretic transfer. Electrophoresis 1990; 11: 46-52. (Pubitemid 20109548)
    • (1990) Electrophoresis , vol.11 , Issue.1 , pp. 46-52
    • Jacobson, G.1    Karsnas, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.