Bithiazole correctors rescue CFTR mutants by two different mechanisms

Biochemistry

Volumn 52, Issue 31, 2013, Pages 5161-5163

  Loo, Tip W ^a   Claire Bartlett, M ^a   Clarke, David M ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BITHIAZOLE; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATORS; DIFFERENT MECHANISMS; NUCLEOTIDE-BINDING DOMAIN;

BIOCHEMISTRY; CHEMISTRY;

REPAIR;

BITHIAZOLE 15JF; BITHIAZOLE 4A; BITHIAZOLE 4D; BITHIAZOLE DERIVATIVE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; LUMACAFTOR; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; DRUG MECHANISM; DRUG PROTEIN BINDING; NUCLEOTIDE BINDING SITE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROCESSING; PROTEIN STRUCTURE;

CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; THIAZOLES;

EID: 84881262864     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi4008758     Document Type: Article

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