Decreased Insulin Clearance in Individuals with Elevated 1-h Post-Load Plasma Glucose Levels

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Marini, Maria Adelaide ^a   Frontoni, Simona ^a   Succurro, Elena ^b   Arturi, Franco ^b   Van Fiorentino, Teresaessa ^b   Sciacqua, Angela ^b   Hribal, Marta Letizia ^b   Perticone, Francesco ^b   Sesti, Giorgio ^b  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; BIOLOGICAL MARKER; GLUCOSE BLOOD LEVEL;

ADULT; ARTICLE; BODY MASS; BODY WEIGHT; CONTROLLED STUDY; DIET RESTRICTION; FAT MASS; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HUMAN; HYPERINSULINEMIA; INSULIN CLEARANCE; INSULIN SENSITIVITY; MAJOR CLINICAL STUDY; MALE; ORAL GLUCOSE TOLERANCE TEST; WAIST CIRCUMFERENCE; AGE; BLOOD; DIABETES MELLITUS, TYPE 2; GLUCOSE TOLERANCE TEST; ITALY; METABOLISM; PHYSIOLOGY; POSTPRANDIAL STATE; SEX DIFFERENCE; STANDARDS; STATISTICAL MODEL; TIME;

AGE FACTORS; BIOLOGICAL MARKERS; BLOOD GLUCOSE; BODY MASS INDEX; BODY WEIGHT; DIABETES MELLITUS, TYPE 2; FEMALE; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN; ITALY; LINEAR MODELS; MALE; POSTPRANDIAL PERIOD; SEX FACTORS; TIME FACTORS;

EID: 84886042353     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0077440     Document Type: Article

References (36)

1. Tuomilehto J, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, et al. (2001) Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med 344: 1343-1350.
2. Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, et al. (2002) Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 346: 393-403.
3. Chiasson JL, Josse RG, Gomis R, Hanefeld M, Karasik A, et al. (2002) Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial. Lancet 359: 2072-2077.
4. DeFronzo RA, Tripathy D, Schwenke DC, Banerji M, Bray GA, et al. (2011) Pioglitazone for diabetes prevention in impaired glucose tolerance. N Engl J Med 364: 1104-1115.
5. Unwin N, Shaw J, Zimmet P, Alberti KGMM, (2002) Impaired glucose tolerance and impaired fasting glycemia: the current status on definition and intervention. Diabet Med 19: 708-723.
6. Gerstein HC, Santaguida P, Raina P, Morrison KM, Balion C, et al. (2007) Annual incidence and relative risk of diabetes in people with various categories of dysglycemia: a systematic overview and meta-analysis of prospective studies. Diabetes Res Clin Pract 78: 305-312.
7. Abdul-Ghani MA, Abdul-Ghani T, Ali N, Defronzo RA, (2008) One-hour plasma glucose concentration and the metabolic syndrome identify subjects at high risk for future type 2 diabetes. Diabetes Care 31: 1650-1655.
8. Abdul-Ghani MA, Lyssenko V, Tuomi T, Defronzo RA, Groop L, (2009) Fasting versus post-load plasma glucose concentration and the risk for future type 2 diabetes: results from the Botnia study. Diabetes Care 32: 281-286.
9. Marini MA, Succurro E, Frontoni S, Mastroianni S, Arturi F, et al. (2012) Insulin sensitivity, β-cell function, and incretin effect in individuals with elevated 1-h postload plasma glucose levels. Diabetes Care 35: 868-872.
10. Bardini G, Dicembrini I, Cresci B, Rotella CM, (2010) Inflammation markers and metabolic characteristics of subjects with 1-h plasma glucose levels. Diabetes Care 33: 411-413.
11. Succurro E, Arturi F, Grembiale A, Iorio F, Fiorentino TV, et al. (2011) One-hour post-load plasma glucose levels are associated with elevated liver enzymes. Nutr Metab Cardiovasc Dis 21: 713-718.
12. Perticone F, Sciacqua A, Tassone EJ, Miceli S, Maio R, et al. (2012) One-hour post-load plasma glucose and IGF-1 in hypertensive patients. Eur J Clin Invest 42: 1325-31.
13. Perticone F, Sciacqua A, Perticone M, Arturi F, Scarpino PE, et al. (2012) Serum uric acid and 1-h postload glucose in essential hypertension. Diabetes Care 2012 35: 153-157.
14. Succurro E, Marini MA, Arturi F, Grembiale A, Lugarà M, et al. (2009) Elevated one-hour post-load plasma glucose levels identifies subjects with normal glucose tolerance but early carotid atherosclerosis. Atherosclerosis 207: 245-249.
15. Sciacqua A, Maio R, Miceli S, Pascale A, Carullo G, et al. (2012) Association between one-hour post-load plasma glucose levels and vascular stiffness in essential hypertension. PLoS One 7: e44470.
16. Succurro E, Arturi F, Lugarà M, Grembiale A, Fiorentino TV, et al. (2010) One-hour postload plasma glucose levels are associated with kidney dysfunction. Clin J Am Soc Nephrol0 5: 1922-1927.
17. Sciacqua A, Miceli S, Carullo G, Greco L, Succurro E, et al. (2011) One-hour post-load plasma glucose levels and left ventricular mass in hypertensive patients. Diabetes Care 34: 1406-1411.
18. Sciacqua A, Miceli S, Greco L, Arturi F, Naccarato P, et al. (2011) One-hour post-load plasma glucose levels and diastolic function in hypertensive patients. Diabetes Care 34: 2291-2296.
19. Duckworth WC, Bennett RG, Hamel FG, (1997) The significance of intracellular insulin to insulin action. J Investig Med 45: 20-27.
20. Duckworth WC, Bennett RG, Hamel FG, (1998) Insulin degradation: progress and potential. Endocr Rev 19: 608-624.
21. Farris W, Mansourian S, Chang Y, Lindsley L, Eckman EA, et al. (2003) Insulin degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo. Proc Natl Acad Sci U S A 100: 4162-4167.
22. Abdul-Hay SO, Kang D, McBride M, Li L, Zhao J, et al. (2011) Deletion of insulin-degrading enzyme elicits antipodal, age-dependent effects on glucose and insulin tolerance. PLoS One 6: e20818.
23. Hribal ML, D'Alfonso R, Giovannone B, Lauro D, Liu YY, et al. (2001) The sulfonylurea glimepiride regulates intracellular routing of the insulin-receptor complexes through their interaction with specific protein kinase C isoforms. Mol Pharmacol 59: 322-330.
24. Sesti G, D'Alfonso R, Vargas Punti MD, Tullio AN, Liu YY, et al. (1996) Delayed intracellular dissociation of the insulin-receptor complex impairs receptor recycling and insulin processing in cultured EBV-transformed lymphocytes from insulin-resistant subjects. Diabetologia 39: 289-297.
25. Bonora E, Zavaroni I, Coscelli C, Butturini U, (1983) Decreased hepatic insulin extraction in subjects with mild glucose intolerance. Metabolism 32: 438-446.
26. Lee CC, Haffner SM, Wagenknecht LE, Lorenzo C, Norris JM, et al. (2013) Insulin Clearance and the Incidence of Type 2 Diabetes in Hispanics and African Americans: The IRAS Family Study. Diabetes Care 36: 901-7.
27. Mittelman SD, Van Citters GW, Kim SP, Davis DA, Dea MK, et al. (2000) Longitudinal compensation for fat-induced insulin resistance includes reduced insulin clearance and enhanced β cell response. Diabetes 49: 2116-2125.
28. Laakso M, Zilinskaite J, Hansen T, Boesgaard TW, Vänttinen M, et al. (2008) Insulin sensitivity, insulin release and GLP-1 levels in subjects with IFG and/or IGT in the EUGENE2 study. Diabetologia 51: 502-511.
29. Marini MA, Frontoni S, Mineo D, Bracaglia D, Cardellini M, et al. (2003) The Arg972variant in insulin receptor substrate-1 is associated with an atherogenic profile in offspring of type 2 diabetic patients. J Clin Endocrinol Metab 88: 3368-3371.
30. DeFronzo RA, Tobin JD, Andres R, (1979) Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol Endocrinol Metab Gastrointest Physiol 237: E214-E223.
31. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, et al. (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28: 412-419.
32. Bonora E, Zavaroni I, Bruschi F, Alpi O, Pezzarossa A, et al. (1984) Peripheral hyperinsulinemia of simple obesity: pancreatic hypersecretion or impaired insulin metabolism? J Clin Endocrinol Metab 59: 1121-1127.
33. Jones CN, Abbasi F, Carantoni M, Polonsky KS, Reaven GM, (2000) Roles of insulin resistance and obesity in regulation of plasma insulin concentrations. Am J Physiol Endocrinol Metab 278: E501-508.
34. Fawcett J, Sang H, Permana PA, Levy JL, Duckworth WC, (2010) Insulin metabolism in human adipocytes from subcutaneous and visceral depots. Biochem Biophys Res Commun 402: 762-766.
35. Castaldo E, Sabato D, Lauro D, Sesti G, Marini MA, (2011) Hypoglycemia assessed by continuous glucose monitoring is associated with preclinical atherosclerosis in individuals with impaired glucose tolerance. PLoS One 12: e28312.
36. Osei K, Gaillard T, Schuster D, (2007) Thiazolidinediones increase hepatic insulin extraction in African Americans with impaired glucose tolerance and type 2 diabetes mellitus. A pilot study of rosiglitazone. Metabolism 56: 24-9.