메뉴 건너뛰기




Volumn 402, Issue 4, 2010, Pages 762-766

Insulin metabolism in human adipocytes from subcutaneous and visceral depots

Author keywords

Human adipose tissue; Insulin degradation; Insulin degrading enzyme; Subcutaneous; Visceral

Indexed keywords

BACITRACIN; CHLOROQUINE; INSULIN; INSULINASE; LEUPEPTIN; PEPSTATIN;

EID: 78649448389     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.10.104     Document Type: Article
Times cited : (16)

References (37)
  • 1
    • 33750938649 scopus 로고    scopus 로고
    • Metabolic obesity: the paradox between visceral and subcutaneous fat
    • Hamdy O., Porramatikul S., Al-Ozairi E. Metabolic obesity: the paradox between visceral and subcutaneous fat. Curr. Diabetes Rev. 2006, 2:367-373.
    • (2006) Curr. Diabetes Rev. , vol.2 , pp. 367-373
    • Hamdy, O.1    Porramatikul, S.2    Al-Ozairi, E.3
  • 2
    • 0033824123 scopus 로고    scopus 로고
    • Obesity and cardiovascular disease. Pathogenetic role of the metabolic syndrome and therapeutic implications
    • Abate N. Obesity and cardiovascular disease. Pathogenetic role of the metabolic syndrome and therapeutic implications. J. Diabetes Complications 2000, 14:154-174.
    • (2000) J. Diabetes Complications , vol.14 , pp. 154-174
    • Abate, N.1
  • 3
    • 33847187395 scopus 로고    scopus 로고
    • Effect of insulin resistance, dyslipidemia, and intra-abdominal adiposity on the development of cardiovascular disease and diabetes mellitus
    • Rader D.J. Effect of insulin resistance, dyslipidemia, and intra-abdominal adiposity on the development of cardiovascular disease and diabetes mellitus. Am. J. Med. 2007, 120:S12-S18.
    • (2007) Am. J. Med. , vol.120
    • Rader, D.J.1
  • 4
    • 0034504237 scopus 로고    scopus 로고
    • Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome
    • Wajchenberg B.L. Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. Endocr. Rev. 2000, 21:697-738.
    • (2000) Endocr. Rev. , vol.21 , pp. 697-738
    • Wajchenberg, B.L.1
  • 5
    • 33846829811 scopus 로고    scopus 로고
    • Abdominal obesity: role in the pathophysiology of metabolic disease and cardiovascular risk
    • (discussion S29-S32)
    • Bergman R.N., Kim S.P., Hsu I.R., Catalano K.J., Chiu J.D., Kabir M., Richey J.M., Ader M. Abdominal obesity: role in the pathophysiology of metabolic disease and cardiovascular risk. Am. J. Med. 2007, 120:S3-S8. (discussion S29-S32).
    • (2007) Am. J. Med. , vol.120
    • Bergman, R.N.1    Kim, S.P.2    Hsu, I.R.3    Catalano, K.J.4    Chiu, J.D.5    Kabir, M.6    Richey, J.M.7    Ader, M.8
  • 6
    • 58049219012 scopus 로고    scopus 로고
    • Adipose tissue dysfunction in obesity, diabetes, and vascular diseases
    • Hajer G.R., van Haeften T.W., Visseren F.L. Adipose tissue dysfunction in obesity, diabetes, and vascular diseases,. Eur. Heart J. 2008, 29:2959-2971.
    • (2008) Eur. Heart J. , vol.29 , pp. 2959-2971
    • Hajer, G.R.1    van Haeften, T.W.2    Visseren, F.L.3
  • 7
    • 74049159942 scopus 로고    scopus 로고
    • Subcutaneous and visceral adipose tissue: structural and functional differences
    • Ibrahim M.M. Subcutaneous and visceral adipose tissue: structural and functional differences. Obes. Rev. 2009, 11:11-18.
    • (2009) Obes. Rev. , vol.11 , pp. 11-18
    • Ibrahim, M.M.1
  • 8
    • 0038341767 scopus 로고    scopus 로고
    • Do regional differences in adipocyte biology provide new pathophysiological insights?
    • Lafontan M., Berlan M. Do regional differences in adipocyte biology provide new pathophysiological insights?. Trends Pharmacol. Sci. 2003, 24:276-283.
    • (2003) Trends Pharmacol. Sci. , vol.24 , pp. 276-283
    • Lafontan, M.1    Berlan, M.2
  • 9
    • 0031739240 scopus 로고    scopus 로고
    • Regional difference in insulin inhibition of non-esterified fatty acid release from human adipocytes: relation to insulin receptor phosphorylation and intracellular signalling through the insulin receptor substrate-1 pathway
    • Zierath J.R., Livingston J.N., Thorne A., Bolinder J., Reynisdottir S., Lonnqvist F., Arner P. Regional difference in insulin inhibition of non-esterified fatty acid release from human adipocytes: relation to insulin receptor phosphorylation and intracellular signalling through the insulin receptor substrate-1 pathway. Diabetologia 1998, 41:1343-1354.
    • (1998) Diabetologia , vol.41 , pp. 1343-1354
    • Zierath, J.R.1    Livingston, J.N.2    Thorne, A.3    Bolinder, J.4    Reynisdottir, S.5    Lonnqvist, F.6    Arner, P.7
  • 10
    • 0020663046 scopus 로고
    • Differences at the receptor and postreceptor levels between human omental and subcutaneous adipose tissue in the action of insulin on lipolysis
    • Bolinder J., Kager L., Ostman J., Arner P. Differences at the receptor and postreceptor levels between human omental and subcutaneous adipose tissue in the action of insulin on lipolysis. Diabetes 1983, 32:117-123.
    • (1983) Diabetes , vol.32 , pp. 117-123
    • Bolinder, J.1    Kager, L.2    Ostman, J.3    Arner, P.4
  • 11
    • 84855624120 scopus 로고    scopus 로고
    • Glucocorticoid-induced insulin resistance in visceral but not subcutaneous human adipocytes
    • [Abs]
    • Lundgren M., Burén J., Myrnäs T., Ruge T., Eriksson J. Glucocorticoid-induced insulin resistance in visceral but not subcutaneous human adipocytes. Diabetes 2003, 52:A84. [Abs].
    • (2003) Diabetes , vol.52
    • Lundgren, M.1    Burén, J.2    Myrnäs, T.3    Ruge, T.4    Eriksson, J.5
  • 13
    • 0021225458 scopus 로고
    • Binding and molecular weight properties of the insulin receptor from omental and subcutaneous adipocytes in human obesity
    • Livingston J.N., Lerea K.M., Bolinder J., Kager L., Backman L., Arner P. Binding and molecular weight properties of the insulin receptor from omental and subcutaneous adipocytes in human obesity. Diabetologia 1984, 27:447-453.
    • (1984) Diabetologia , vol.27 , pp. 447-453
    • Livingston, J.N.1    Lerea, K.M.2    Bolinder, J.3    Kager, L.4    Backman, L.5    Arner, P.6
  • 15
    • 0032551258 scopus 로고    scopus 로고
    • Pathogenesis of HIV-1-protease inhibitor-associated peripheral lipodystrophy, hyperlipidaemia, and insulin resistance
    • Carr A., Samaras K., Chisholm D.J., Cooper D.A. Pathogenesis of HIV-1-protease inhibitor-associated peripheral lipodystrophy, hyperlipidaemia, and insulin resistance. Lancet 1998, 351:1881-1883.
    • (1998) Lancet , vol.351 , pp. 1881-1883
    • Carr, A.1    Samaras, K.2    Chisholm, D.J.3    Cooper, D.A.4
  • 16
    • 78649445928 scopus 로고    scopus 로고
    • Fat accumulation and HIV-1 protease inhibitors
    • Martinez E. Fat accumulation and HIV-1 protease inhibitors. Lancet 1998, 352:1392.
    • (1998) Lancet , vol.352 , pp. 1392
    • Martinez, E.1
  • 17
    • 0034617191 scopus 로고    scopus 로고
    • The mechanism of insulin resistance caused by HIV protease inhibitor therapy
    • Murata H., Hruz P.W., Mueckler M. The mechanism of insulin resistance caused by HIV protease inhibitor therapy. J. Biol. Chem. 2000, 275:20251-20254.
    • (2000) J. Biol. Chem. , vol.275 , pp. 20251-20254
    • Murata, H.1    Hruz, P.W.2    Mueckler, M.3
  • 20
    • 13244284831 scopus 로고    scopus 로고
    • Buffalo hump seen in HIV-associated lipodystrophy is associated with hyperinsulinemia but not dyslipidemia
    • Mallon P.W., Wand H., Law M., Miller J., Cooper D.A., Carr A. Buffalo hump seen in HIV-associated lipodystrophy is associated with hyperinsulinemia but not dyslipidemia. J. Acquir. Immune Defic. Syndr. 2005, 38:156-162.
    • (2005) J. Acquir. Immune Defic. Syndr. , vol.38 , pp. 156-162
    • Mallon, P.W.1    Wand, H.2    Law, M.3    Miller, J.4    Cooper, D.A.5    Carr, A.6
  • 21
    • 0034731520 scopus 로고    scopus 로고
    • Suppression of preadipocyte differentiation and promotion of adipocyte death by HIV protease inhibitors
    • Dowell P., Flexner C., Kwiterovich P.O., Lane M.D. Suppression of preadipocyte differentiation and promotion of adipocyte death by HIV protease inhibitors. J. Biol. Chem. 2000, 275:41325-41332.
    • (2000) J. Biol. Chem. , vol.275 , pp. 41325-41332
    • Dowell, P.1    Flexner, C.2    Kwiterovich, P.O.3    Lane, M.D.4
  • 23
    • 0036148177 scopus 로고    scopus 로고
    • The HIV protease inhibitor saquinavir impairs lipid metabolism and glucose transport in cultured adipocytes
    • Ranganathan S., Kern P.A. The HIV protease inhibitor saquinavir impairs lipid metabolism and glucose transport in cultured adipocytes. J. Endocrinol. 2002, 172:155-162.
    • (2002) J. Endocrinol. , vol.172 , pp. 155-162
    • Ranganathan, S.1    Kern, P.A.2
  • 25
    • 0032487042 scopus 로고    scopus 로고
    • Metabolic abnormalities and use of HIV-1 protease inhibitors
    • Martinez E., Gatell J. Metabolic abnormalities and use of HIV-1 protease inhibitors. Lancet 1998, 352:821-822.
    • (1998) Lancet , vol.352 , pp. 821-822
    • Martinez, E.1    Gatell, J.2
  • 26
    • 33749498028 scopus 로고    scopus 로고
    • Effect of nelfinavir on insulin metabolism, proteasome activity and protein degradation in HepG2 cells
    • Hamel F.G., Fawcett J., Tsui B.T., Bennett R.G., Duckworth W.C. Effect of nelfinavir on insulin metabolism, proteasome activity and protein degradation in HepG2 cells. Diabetes Obes. Metab. 2006, 8:661-668.
    • (2006) Diabetes Obes. Metab. , vol.8 , pp. 661-668
    • Hamel, F.G.1    Fawcett, J.2    Tsui, B.T.3    Bennett, R.G.4    Duckworth, W.C.5
  • 27
  • 28
    • 57249104708 scopus 로고    scopus 로고
    • Weight-dependent differential contribution of insulin secretion and clearance to hyperinsulinemia of obesity
    • Erdmann J., Mayr M., Oppel U., Sypchenko O., Wagenpfeil S., Schusdziarra V. Weight-dependent differential contribution of insulin secretion and clearance to hyperinsulinemia of obesity. Regul. Pept. 2009, 152:1-7.
    • (2009) Regul. Pept. , vol.152 , pp. 1-7
    • Erdmann, J.1    Mayr, M.2    Oppel, U.3    Sypchenko, O.4    Wagenpfeil, S.5    Schusdziarra, V.6
  • 32
    • 0035862174 scopus 로고    scopus 로고
    • Characterization of the inhibition of protein degradation by insulin in L6 cells
    • Fawcett J., Hamel F.G., Duckworth W.C. Characterization of the inhibition of protein degradation by insulin in L6 cells. Arch. Biochem. Biophys. 2001, 385:357-363.
    • (2001) Arch. Biochem. Biophys. , vol.385 , pp. 357-363
    • Fawcett, J.1    Hamel, F.G.2    Duckworth, W.C.3
  • 33
    • 0027983795 scopus 로고
    • Androgen and glucocorticoid receptors interact with insulin degrading enzyme
    • Kupfer S.R., Wilson E.M., French F.S. Androgen and glucocorticoid receptors interact with insulin degrading enzyme. J. Biol. Chem. 1994, 269:20622-20628.
    • (1994) J. Biol. Chem. , vol.269 , pp. 20622-20628
    • Kupfer, S.R.1    Wilson, E.M.2    French, F.S.3
  • 34
    • 0028102743 scopus 로고
    • A direct inhibitory effect of insulin on a cytosolic proteolytic complex containing insulin-degrading enzyme and multicatalytic proteinase
    • Duckworth W.C., Bennett R.G., Hamel F.G. A direct inhibitory effect of insulin on a cytosolic proteolytic complex containing insulin-degrading enzyme and multicatalytic proteinase. J. Biol. Chem. 1994, 269:24575-24580.
    • (1994) J. Biol. Chem. , vol.269 , pp. 24575-24580
    • Duckworth, W.C.1    Bennett, R.G.2    Hamel, F.G.3
  • 35
    • 0034457014 scopus 로고    scopus 로고
    • Insulin inhibits the ubiquitin-dependent degrading activity of the 26S proteasome
    • Bennett R.G., Hamel F.G., Duckworth W.C. Insulin inhibits the ubiquitin-dependent degrading activity of the 26S proteasome. Endocrinology 2000, 141:2508-2517.
    • (2000) Endocrinology , vol.141 , pp. 2508-2517
    • Bennett, R.G.1    Hamel, F.G.2    Duckworth, W.C.3
  • 36
    • 0035009436 scopus 로고    scopus 로고
    • Insulin inhibits peroxisomal fatty acid oxidation in isolated rat hepatocytes
    • Hamel F.G., Bennett R.G., Upward J.L., Duckworth W.C. Insulin inhibits peroxisomal fatty acid oxidation in isolated rat hepatocytes. Endocrinology 2001, 142:2702-2706.
    • (2001) Endocrinology , vol.142 , pp. 2702-2706
    • Hamel, F.G.1    Bennett, R.G.2    Upward, J.L.3    Duckworth, W.C.4
  • 37
    • 0037088652 scopus 로고    scopus 로고
    • Endosomal proteolysis of internalized insulin at the C-terminal region of the B chain by cathepsin D
    • Authier F., Metioui M., Fabrega S., Kouach M., Briand G. Endosomal proteolysis of internalized insulin at the C-terminal region of the B chain by cathepsin D. J. Biol. Chem. 2002, 277:9437-9446.
    • (2002) J. Biol. Chem. , vol.277 , pp. 9437-9446
    • Authier, F.1    Metioui, M.2    Fabrega, S.3    Kouach, M.4    Briand, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.