Glucose induces expression of rat pyruvate carboxylase through a carbohydrate response element in the distal gene promoter

Biochemical Journal

Volumn 426, Issue 2, 2010, Pages 159-170

  Pedersen, Kim B ^a   Buckley, Rebecca S ^a   Scioneaux, Ray ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Carbohydrate response element (ChoRE); Carbohydrate response element binding protein (ChREBP); E box; insulinoma; Max like protein X (Mlx); Pyruvate carboxylase

Indexed keywords

GENE PROMOTER; GLUCOSE CONCENTRATION; GLUCOSE RESPONSE; GLUCOSE-STIMULATED INSULIN SECRETIONS; HETEROLOGOUS GENES; IN-SITU; IN-VITRO; INSULINOMA CELLS; OVER-EXPRESSION; PROMOTER REGION; PYRUVATE CARBOXYLASE; PYRUVATES; RESPONSE ELEMENTS; TRANSCRIPTION FACTOR-3; TRANSCRIPTION START SITE;

CARBOHYDRATES; CELL CULTURE; GLUCOSE; TRANSCRIPTION FACTORS;

TRANSCRIPTION;

BINDING PROTEIN; CARBOHYDRATE RESPONSE ELEMENT BINDING PROTEIN; GLUCOSE; PYRUVATE CARBOXYLASE; UNCLASSIFIED DRUG; UPSTREAM STIMULATORY FACTOR 1; UPSTREAM STIMULATORY FACTOR 2;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE DELETION; GENE EXPRESSION; IN VITRO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; RAT; TRANSCRIPTION INITIATION SITE; UPREGULATION;

ANIMALS; BASE SEQUENCE; BINDING SITES; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCOSE; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PYRUVATE CARBOXYLASE; RATS; RESPONSE ELEMENTS; SEQUENCE DELETION; TRANSCRIPTIONAL ACTIVATION;

RATTUS;

EID: 76549095463     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20091266     Document Type: Article

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